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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Sec11c (spascer ID:66286)

Gene summary for Sec11c

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Sec11c
	Gene ID	66286
	Gene name	SEC11 homolog C, signal peptidase complex subunit
	Synonyms	1810029G24Rik\|Sec11l3
	Cytomap	18\|18 E1
	Type of gene	protein-coding
	Description	signal peptidase complex catalytic subunit SEC11CSEC11-like protein 3SPC21SPase 21 kDa subunitSec11-like 3microsomal signal peptidase 21 kDa subunit
	Modification date	20220424
	UniProtAcc	Q9D8V7

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Sec11c	GO:0005787	signal peptidase complex	21873635	Component
Sec11c	GO:0006465	signal peptide processing	21873635	Process
Sec11c	GO:0008233	peptidase activity	21873635	Function

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Spatial pattern events for Sec11c

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Sec11c	Mouse	Brain	S1	34413515	2.45e-06
Sec11c	Mouse	Brain	S2	34413515	1.56e-15
Sec11c	Mouse	Brain	S3	34413515	1.64e-15
Sec11c	Mouse	Brain	S4	34413515	1.37e-15
Sec11c	Mouse	Brain	S6	34413515	2.66e-15
Sec11c	Mouse	Brain	S7	34413515	1.55e-15
Sec11c	Mouse	Brain	12B	32637622	6.70e-13
Sec11c	Mouse	Brain	22B	32637622	2.14e-10
Sec11c	Mouse	Brain	24B	32637622	2.66e-06
Sec11c	Mouse	Brain	27A	32637622	1.65e-07
Sec11c	Mouse	Brain	28A	32637622	5.64e-09
Sec11c	Mouse	Brain	29A	32637622	7.97e-09
Sec11c	Mouse	Brain	30A	32637622	9.25e-10
Sec11c	Mouse	Brain	32A	32637622	7.07e-12
Sec11c	Mouse	Brain	33A	32637622	8.22e-08
Sec11c	Mouse	Brain	33B	32637622	2.12e-06
Sec11c	Mouse	Brain	34A	32637622	3.34e-10
Sec11c	Mouse	Brain	34B	32637622	3.07e-14
Sec11c	Mouse	Brain	35A	32637622	5.66e-07
Sec11c	Mouse	Brain	35B	32637622	3.15e-08
Sec11c	Mouse	Brain	36B	32637622	6.45e-07
Sec11c	Mouse	Brain	38B	32637622	5.40e-13
Sec11c	Mouse	Brain	rep_1	35141374	2.02e-15
Sec11c	Mouse	Brain	rep_2	35141374	1.69e-15
Sec11c	Mouse	Brain	rep_3	35141374	1.64e-15
Sec11c	Mouse	Brain	rep_4	35141374	1.57e-15
Sec11c	Mouse	Brain	rep_5	35141374	1.47e-15
Sec11c	Mouse	Brain	rep_6	35141374	1.73e-15
Sec11c	Mouse	Kidney	IRI	34003797	9.04e-08
Sec11c	Mouse	Brain	rep_1	33469025	1.30e-15
Sec11c	Mouse	Brain	rep_1	35027729	1.66e-15
Sec11c	Mouse	Brain	rep_2	35027729	1.57e-15
Sec11c	Mouse	Brain	rep_3	35027729	1.32e-15
Sec11c	Mouse	Brain	rep_4	35027729	1.76e-15
Sec11c	Mouse	Brain	rep_5	35027729	1.46e-15
Sec11c	Mouse	Intestine	rep_3	35149721	5.21e-15
Sec11c	Mouse	Intestine	rep_4	35149721	2.30e-15
Sec11c	Mouse	Brain	B05_D2	32702314	1.27e-07
Sec11c	Mouse	Lymph	A1	0	3.29e-15
Sec11c	Mouse	Lymph	B1	0	3.66e-15
Sec11c	Mouse	Lung	rep_1	35290801	6.56e-15
Sec11c	Mouse	Lung	rep_2	35290801	3.54e-14
Sec11c	Mouse	Lung	rep_3	35290801	8.40e-15
Sec11c	Mouse	Lung	rep_4	35290801	9.78e-06
Sec11c	Mouse	Brain	rep_1	35210624	1.19e-06
Sec11c	Mouse	Brain	rep_2	35210624	1.59e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_IRI_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B05_D2_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Sec11c envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Sec11c	GOBP_Protein_Maturation	Mouse	Spinal cord	CN94_E1	2.2e-06
Sec11c	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Sec11c	GOBP_Peptide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Sec11c	GOBP_Protein_Processing	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Sec11c	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Sec11c	GOBP_Signal_Peptide_Processing	Mouse	Spinal cord	L7CN45_C1	4.9e-08
Sec11c	GOBP_Signal_Peptide_Processing	Mouse	Brain	rep_41	1.4e-08
Sec11c	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Sec11c	GOBP_Peptide_Metabolic_Process	Mouse	Brain	rep_3	1.3e-86
Sec11c	GOBP_Protein_Maturation	Mouse	Brain	rep_3	1.1e-160
Sec11c	GOBP_Protein_Processing	Mouse	Brain	rep_3	2.3e-168
Sec11c	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
Sec11c	GOBP_Signal_Peptide_Processing	Mouse	Brain	rep_3	3.0e-189
Sec11c	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Sec11c	GOBP_Peptide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Sec11c	GOBP_Protein_Maturation	Mouse	Embryo	rep_14	6.3e-10
Sec11c	GOBP_Protein_Processing	Mouse	Embryo	rep_14	4.6e-22
Sec11c	GOBP_Signal_Peptide_Processing	Mouse	Embryo	rep_14	3.4e-49
Sec11c	GOBP_Protein_Maturation	Mouse	Kidney	IRI	2.5e-33
Sec11c	GOBP_Protein_Processing	Mouse	Kidney	IRI	4.8e-57
Sec11c	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
Sec11c	GOBP_Protein_Processing	Mouse	Kidney	rep_1	8.0e-08
Sec11c	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Sec11c	GOBP_Peptide_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-80
Sec11c	GOBP_Protein_Maturation	Mouse	Kidney	rep_2	5.4e-103
Sec11c	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
Sec11c	GOBP_Signal_Peptide_Processing	Mouse	Kidney	rep_2	8.7e-112
Sec11c	GOBP_Signal_Peptide_Processing	Mouse	Liver	CN16-D2	6.5e-08
Sec11c	GOBP_Protein_Maturation	Mouse	Liver	rep_16	4.5e-09
Sec11c	GOBP_Protein_Processing	Mouse	Liver	rep_16	3.8e-09
Sec11c	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Sec11c	GOBP_Peptide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Sec11c	GOBP_Protein_Processing	Mouse	Lymph	MS-1	8.5e-10
Sec11c	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
Sec11c	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Sec11c	GOBP_Peptide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Sec11c	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
Sec11c	GOBP_Signal_Peptide_Processing	Mouse	Brain	HP_adpolb_rep6	1.2e-07
Sec11c	GOBP_Protein_Maturation	Mouse	Brain	HP_polb_rep9	9.1e-14
Sec11c	GOBP_Protein_Processing	Mouse	Brain	HP_polb_rep9	1.6e-12

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Sec11c function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Sec11c function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Sec11c envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Sec11c

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Sec11c

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source