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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Tmem126a (spascer ID:66271)

Gene summary for Tmem126a

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Tmem126a
	Gene ID	66271
	Gene name	transmembrane protein 126A
	Synonyms	1810020E01Rik
	Cytomap	7\|7 E1
	Type of gene	protein-coding
	Description	transmembrane protein 126A
	Modification date	20220424
	UniProtAcc	Q9D8Y1

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Tmem126a	GO:0005739	mitochondrion	21873635	Component
Tmem126a	GO:0032981	mitochondrial respiratory chain complex I assembly	21873635	Process

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Spatial pattern events for Tmem126a

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Tmem126a	Mouse	Brain	S2	34413515	1.06e-11
Tmem126a	Mouse	Brain	S4	34413515	2.12e-07
Tmem126a	Mouse	Kidney	IRI	34003797	2.51e-13
Tmem126a	Mouse	Brain	rep_1	33469025	3.61e-09
Tmem126a	Mouse	Brain	rep_1	35027729	3.15e-10
Tmem126a	Mouse	Brain	rep_2	35027729	4.48e-14
Tmem126a	Mouse	Brain	rep_3	35027729	1.20e-08
Tmem126a	Mouse	Brain	rep_4	35027729	5.87e-15
Tmem126a	Mouse	Brain	rep_5	35027729	3.84e-10
Tmem126a	Mouse	Lymph	A1	0	8.76e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_IRI_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Tmem126a envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Tmem126a	GOBP_Cranial_Nerve_Development	Mouse	Spinal cord	L7CN45_C1	5.4e-06
Tmem126a	GOBP_Mitochondrion_Organization	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Tmem126a	GOBP_Nerve_Development	Mouse	Spinal cord	L7CN45_C1	2.2e-06
Tmem126a	GOBP_Optic_Nerve_Development	Mouse	Spinal cord	L7CN45_C1	4.1e-06
Tmem126a	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Mouse	Spinal cord	L7CN47_D1	3.7e-06
Tmem126a	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Mouse	Spinal cord	L7CN47_D1	2.6e-06
Tmem126a	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Mouse	Brain	rep_71	2.8e-06
Tmem126a	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Mouse	Brain	rep_71	3.5e-06
Tmem126a	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Mouse	Brain	rep_1	5.0e-26
Tmem126a	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Mouse	Brain	rep_1	9.2e-45
Tmem126a	GOBP_Cranial_Nerve_Development	Mouse	Brain	rep_3	1.5e-52
Tmem126a	GOBP_Mitochondrion_Organization	Mouse	Brain	rep_3	1.3e-89
Tmem126a	GOBP_Nerve_Development	Mouse	Brain	rep_3	2.0e-115
Tmem126a	GOBP_Optic_Nerve_Development	Mouse	Brain	rep_3	9.6e-105
Tmem126a	GOBP_Cranial_Nerve_Development	Mouse	Embryo	rep_14	3.9e-20
Tmem126a	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Mouse	Embryo	rep_14	5.0e-27
Tmem126a	GOBP_Mitochondrion_Organization	Mouse	Embryo	rep_14	1.8e-11
Tmem126a	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Mouse	Embryo	rep_14	2.8e-58
Tmem126a	GOBP_Nerve_Development	Mouse	Embryo	rep_14	3.1e-30
Tmem126a	GOBP_Optic_Nerve_Development	Mouse	Embryo	rep_14	7.6e-27
Tmem126a	GOBP_Cranial_Nerve_Development	Mouse	Embryo	rep_1	1.3e-81
Tmem126a	GOBP_Nerve_Development	Mouse	Embryo	rep_1	5.5e-32
Tmem126a	GOBP_Mitochondrion_Organization	Mouse	Embryo	rep_3	4.0e-48
Tmem126a	GOBP_Cranial_Nerve_Development	Mouse	Kidney	rep_2	4.8e-22
Tmem126a	GOBP_Mitochondrion_Organization	Mouse	Kidney	rep_2	1.7e-21
Tmem126a	GOBP_Nerve_Development	Mouse	Kidney	rep_2	4.3e-44
Tmem126a	GOBP_Optic_Nerve_Development	Mouse	Kidney	rep_2	1.8e-11
Tmem126a	GOBP_Optic_Nerve_Development	Mouse	Liver	CN65-C1	4.2e-09
Tmem126a	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Mouse	Liver	rep_16	4.3e-23
Tmem126a	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Mouse	Liver	rep_16	3.7e-23
Tmem126a	GOBP_Cranial_Nerve_Development	Mouse	Lymph	MS-1	2.3e-14
Tmem126a	GOBP_Mitochondrion_Organization	Mouse	Lymph	MS-1	4.2e-09
Tmem126a	GOBP_Nerve_Development	Mouse	Lymph	MS-1	2.7e-14
Tmem126a	GOBP_Optic_Nerve_Development	Mouse	Lymph	MS-1	2.2e-11
Tmem126a	GOBP_Cranial_Nerve_Development	Mouse	Brain	HP_ad_rep7	5.0e-12
Tmem126a	GOBP_Optic_Nerve_Development	Mouse	Brain	HP_adpolb_rep1	7.2e-12
Tmem126a	GOBP_Mitochondrial_Respiratory_Chain_Complex_Assembly	Mouse	Brain	HP_polb_rep9	7.2e-14
Tmem126a	GOBP_Mitochondrion_Organization	Mouse	Brain	HP_polb_rep9	1.2e-11
Tmem126a	GOBP_Nadh_Dehydrogenase_Complex_Assembly	Mouse	Brain	HP_polb_rep9	1.3e-07

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Tmem126a function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Tmem126a function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand	Receptor	LR pair	Tissue	Replication
Tnfsf9	Tmem126a	Tnfsf9_Tmem126a	Brain	rep_3

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Transcription factor for Tmem126a envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Tmem126a

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Tmem126a

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Tmem126a	C2751812	OPTIC ATROPHY 7 (disorder)	3	CTD_human;GENOMICS_ENGLAND;ORPHANET