|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: Eif1ax (spascer ID:66235) |
Gene summary for Eif1ax |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Eif1ax | Gene ID | 66235 |
| Gene name | eukaryotic translation initiation factor 1A, X-linked |
| Synonyms | 1500010B24Rik|AI426898|Eif1ay|eIF-4C |
| Cytomap | X|X F4 |
| Type of gene | protein-coding |
| Description | eukaryotic translation initiation factor 1A, X-chromosomaleukaryotic translation initiation factor 1A, Y-linkedeukaryotic translation initiation factor 4C |
| Modification date | 20220424 |
| UniProtAcc | Q8BMJ3 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Eif1ax | GO:0003743 | translation initiation factor activity | 21873635 | Function |
| Eif1ax | GO:0005737 | cytoplasm | 21873635 | Component |
| Eif1ax | GO:0006413 | translational initiation | 21873635 | Process |
Top |
Spatial pattern events for Eif1ax |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Eif1ax | Mouse | Brain | S1 | 34413515 | 3.73e-15 |
| Eif1ax | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Eif1ax | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Eif1ax | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Eif1ax | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Eif1ax | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Eif1ax | Mouse | Brain | rep_1 | 35141374 | 3.58e-15 |
| Eif1ax | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Eif1ax | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Eif1ax | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Eif1ax | Mouse | Brain | rep_5 | 35141374 | 2.68e-15 |
| Eif1ax | Mouse | Brain | rep_6 | 35141374 | 2.34e-14 |
| Eif1ax | Mouse | Embryo | rep_3 | 33188776 | 4.27e-10 |
| Eif1ax | Mouse | Embryo | rep_13 | 33188776 | 3.31e-08 |
| Eif1ax | Mouse | Kidney | IRI | 34003797 | 5.55e-12 |
| Eif1ax | Mouse | Kidney | rep_5 | 34853151 | 1.25e-10 |
| Eif1ax | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Eif1ax | Mouse | Brain | rep_1 | 35027729 | 5.64e-15 |
| Eif1ax | Mouse | Brain | rep_2 | 35027729 | 1.11e-11 |
| Eif1ax | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Eif1ax | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Eif1ax | Mouse | Brain | rep_5 | 35027729 | 2.62e-15 |
| Eif1ax | Mouse | Intestine | rep_4 | 35149721 | 1.25e-06 |
| Eif1ax | Mouse | Testicle | rep_5 | 34731600 | 2.03e-14 |
| Eif1ax | Mouse | Lung | rep_1 | 35290801 | 9.34e-12 |
| Eif1ax | Mouse | Lung | rep_2 | 35290801 | 8.75e-15 |
| Eif1ax | Mouse | Lung | rep_3 | 35290801 | 1.52e-14 |
| Eif1ax | Mouse | Lung | rep_4 | 35290801 | 5.40e-15 |
| Eif1ax | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Eif1ax | Mouse | Brain | rep_2 | 35210624 | 1.74e-15 |
| Eif1ax | Mouse | Brain | rep_3 | 35210624 | 1.82e-15 |
| Eif1ax | Mouse | Brain | rep_5 | 35210624 | 2.07e-10 |
| Eif1ax | Mouse | Brain | rep_6 | 35210624 | 5.98e-08 |
| Eif1ax | Mouse | Brain | rep_7 | 35210624 | 3.31e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
Lung_rep_3_H&E  |  |
Lung_rep_4_H&E  |  |
Top |
Spatial pattern pathway has Eif1ax envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Eif1ax | GOBP_Amide_Biosynthetic_Process | Mouse | Spinal cord | L7CN45_C1 | 2.2e-09 |
| Eif1ax | GOBP_Cellular_Amide_Metabolic_Process | Mouse | Spinal cord | L7CN45_C1 | 3.4e-09 |
| Eif1ax | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Spinal cord | L7CN45_C1 | 5.6e-08 |
| Eif1ax | GOBP_Peptide_Biosynthetic_Process | Mouse | Spinal cord | L7CN45_C1 | 3.5e-08 |
| Eif1ax | GOBP_Peptide_Metabolic_Process | Mouse | Spinal cord | L7CN45_C1 | 3.4e-09 |
| Eif1ax | GOBP_Translational_Initiation | Mouse | Spinal cord | L7CN45_C1 | 1.6e-08 |
| Eif1ax | GOBP_Amide_Biosynthetic_Process | Mouse | Brain | rep_3 | 2.5e-86 |
| Eif1ax | GOBP_Cellular_Amide_Metabolic_Process | Mouse | Brain | rep_3 | 2.1e-87 |
| Eif1ax | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Brain | rep_3 | 2.9e-144 |
| Eif1ax | GOBP_Peptide_Biosynthetic_Process | Mouse | Brain | rep_3 | 2.1e-69 |
| Eif1ax | GOBP_Peptide_Metabolic_Process | Mouse | Brain | rep_3 | 1.3e-86 |
| Eif1ax | GOBP_Translational_Initiation | Mouse | Brain | rep_3 | 1.2e-197 |
| Eif1ax | GOBP_Amide_Biosynthetic_Process | Mouse | Embryo | rep_14 | 3.7e-18 |
| Eif1ax | GOBP_Cellular_Amide_Metabolic_Process | Mouse | Embryo | rep_14 | 4.7e-16 |
| Eif1ax | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Embryo | rep_14 | 2.4e-12 |
| Eif1ax | GOBP_Peptide_Biosynthetic_Process | Mouse | Embryo | rep_14 | 2.8e-15 |
| Eif1ax | GOBP_Peptide_Metabolic_Process | Mouse | Embryo | rep_14 | 4.7e-16 |
| Eif1ax | GOBP_Translational_Initiation | Mouse | Embryo | rep_14 | 1.2e-37 |
| Eif1ax | GOBP_Amide_Biosynthetic_Process | Mouse | Kidney | rep_2 | 1.9e-84 |
| Eif1ax | GOBP_Cellular_Amide_Metabolic_Process | Mouse | Kidney | rep_2 | 2.5e-85 |
| Eif1ax | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Kidney | rep_2 | 8.9e-78 |
| Eif1ax | GOBP_Peptide_Biosynthetic_Process | Mouse | Kidney | rep_2 | 2.9e-85 |
| Eif1ax | GOBP_Peptide_Metabolic_Process | Mouse | Kidney | rep_2 | 1.4e-80 |
| Eif1ax | GOBP_Translational_Initiation | Mouse | Kidney | rep_2 | 1.3e-103 |
| Eif1ax | GOBP_Amide_Biosynthetic_Process | Mouse | Lymph | MS-1 | 1.3e-09 |
| Eif1ax | GOBP_Cellular_Amide_Metabolic_Process | Mouse | Lymph | MS-1 | 5.8e-11 |
| Eif1ax | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Lymph | MS-1 | 1.4e-09 |
| Eif1ax | GOBP_Peptide_Biosynthetic_Process | Mouse | Lymph | MS-1 | 7.1e-07 |
| Eif1ax | GOBP_Peptide_Metabolic_Process | Mouse | Lymph | MS-1 | 5.8e-11 |
| Eif1ax | GOBP_Translational_Initiation | Mouse | Lymph | MS-1 | 7.5e-07 |
| Eif1ax | GOBP_Amide_Biosynthetic_Process | Mouse | Brain | HP_ad_rep7 | 8.0e-10 |
| Eif1ax | GOBP_Cellular_Amide_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 5.6e-11 |
| Eif1ax | GOBP_Organonitrogen_Compound_Biosynthetic_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-08 |
| Eif1ax | GOBP_Peptide_Biosynthetic_Process | Mouse | Brain | HP_ad_rep7 | 4.4e-10 |
| Eif1ax | GOBP_Peptide_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-10 |
| Eif1ax | GOBP_Translational_Initiation | Mouse | Brain | HP_ad_rep7 | 6.9e-08 |
Top |
Eif1ax function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
Eif1ax function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for Eif1ax envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for Eif1ax |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for Eif1ax |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Eif1ax | C0027627 | Neoplasm Metastasis | 1 | CTD_human |
| Eif1ax | C0220633 | Uveal melanoma | 1 | CTD_human |
| Eif1ax | C0238463 | Papillary thyroid carcinoma | 1 | ORPHANET |
