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Spatial pattern gene: Commd6 (spascer ID:66200) |
Gene summary for Commd6 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Commd6 | Gene ID | 66200 |
| Gene name | COMM domain containing 6 |
| Synonyms | 1110059J08Rik|1700063H17Rik |
| Cytomap | 14|14 E2.3 |
| Type of gene | protein-coding |
| Description | COMM domain-containing protein 6 |
| Modification date | 20220424 |
| UniProtAcc | Q3V4B5 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Commd6 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 21873635 | Process |
| Commd6 | GO:0051059 | NF-kappaB binding | 21873635 | Function |
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Spatial pattern events for Commd6 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Commd6 | Mouse | Brain | S4 | 34413515 | 4.67e-06 |
| Commd6 | Mouse | Brain | S7 | 34413515 | 2.75e-06 |
| Commd6 | Mouse | Brain | rep_6 | 35141374 | 7.51e-09 |
| Commd6 | Mouse | Kidney | Sham | 34003797 | 4.36e-10 |
| Commd6 | Mouse | Liver | rep_20 | 35021063 | 5.05e-07 |
| Commd6 | Mouse | Brain | rep_3 | 35027729 | 5.81e-10 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_6_H&E  |  |
Kidney_Sham_H&E  |  |
Liver_rep_20_H&E  | |
Brain_rep_3_H&E  |  |
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Spatial pattern pathway has Commd6 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Commd6 | GOBP_Negative_Regulation_Of_Molecular_Function | Mouse | Spinal cord | L7CN45_C1 | 1.1e-06 |
| Commd6 | GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_Activity | Mouse | Spinal cord | L7CN45_C1 | 2.0e-06 |
| Commd6 | GOBP_Negative_Regulation_Of_Molecular_Function | Mouse | Brain | rep_1 | 1.0e-08 |
| Commd6 | GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_Activity | Mouse | Brain | rep_1 | 1.0e-06 |
| Commd6 | GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_Activity | Mouse | Brain | rep_3 | 4.3e-75 |
| Commd6 | GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity | Mouse | Brain | rep_3 | 1.8e-138 |
| Commd6 | GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_Activity | Mouse | Embryo | rep_6 | 1.4e-07 |
| Commd6 | GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_Activity | Mouse | Embryo | rep_6 | 9.0e-09 |
| Commd6 | GOBP_Negative_Regulation_Of_Molecular_Function | Mouse | Kidney | Nep | 8.3e-23 |
| Commd6 | GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_Activity | Mouse | Kidney | rep_2 | 3.3e-62 |
| Commd6 | GOBP_Negative_Regulation_Of_Molecular_Function | Mouse | Kidney | rep_2 | 2.5e-99 |
| Commd6 | GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_Activity | Mouse | Kidney | rep_2 | 1.5e-50 |
| Commd6 | GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity | Mouse | Kidney | rep_2 | 2.6e-30 |
| Commd6 | GOBP_Negative_Regulation_Of_Molecular_Function | Mouse | Liver | CN73-C1 | 9.9e-07 |
| Commd6 | GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_Activity | Mouse | Lymph | MS-1 | 3.0e-08 |
| Commd6 | GOBP_Negative_Regulation_Of_Molecular_Function | Mouse | Lymph | MS-1 | 6.9e-11 |
| Commd6 | GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_Activity | Mouse | Lymph | MS-1 | 2.7e-08 |
| Commd6 | GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity | Mouse | Lymph | MS-1 | 8.0e-12 |
| Commd6 | GOBP_Negative_Regulation_Of_Molecular_Function | Mouse | Lung | rep_1 | 9.4e-15 |
| Commd6 | GOBP_Negative_Regulation_Of_Molecular_Function | Mouse | Brain | HP_ad_rep7 | 3.4e-10 |
| Commd6 | GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_Activity | Mouse | Brain | HP_polb_rep9 | 2.1e-11 |
| Commd6 | GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_Activity | Mouse | Brain | HP_polb_rep9 | 6.3e-08 |
| Commd6 | GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_Activity | Mouse | Brain | HP_polb_rep9 | 7.0e-08 |
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Commd6 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Commd6 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Commd6 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Commd6 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Commd6 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
