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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Lage3 (spascer ID:66192)

Gene summary for Lage3

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Lage3
	Gene ID	66192
	Gene name	L antigen family, member 3
	Synonyms	1110049G11Rik\|Eso3\|Itba2
	Cytomap	X\|X A7.3
	Type of gene	protein-coding
	Description	EKC/KEOPS complex subunit Lage3ITBA2 protein homolog
	Modification date	20220424
	UniProtAcc	Q9CR70

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Lage3	GO:0000408	EKC/KEOPS complex	21873635	Component
Lage3	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	21873635	Process

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Spatial pattern events for Lage3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Lage3	Mouse	Brain	S2	34413515	1.09e-14
Lage3	Mouse	Brain	S4	34413515	1.37e-15
Lage3	Mouse	Brain	S6	34413515	2.04e-09
Lage3	Mouse	Brain	S7	34413515	3.53e-08
Lage3	Mouse	Brain	rep_2	35141374	7.43e-11
Lage3	Mouse	Brain	rep_3	35141374	5.89e-10
Lage3	Mouse	Brain	rep_4	35141374	1.73e-09
Lage3	Mouse	Kidney	rep_1	34853151	6.06e-13
Lage3	Mouse	Brain	rep_1	33469025	2.37e-15
Lage3	Mouse	Brain	rep_2	35027729	6.58e-08
Lage3	Mouse	Brain	rep_3	35027729	7.15e-09
Lage3	Mouse	Intestine	rep_4	35149721	4.22e-14
Lage3	Mouse	Brain	rep_2	35210624	3.88e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E

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Spatial pattern pathway has Lage3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Lage3	GOBP_Trna_Threonylcarbamoyladenosine_Metabolic_Process	Mouse	Spinal cord	L7CN30_D2	9.6e-06
Lage3	GOBP_Ncrna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.5e-07
Lage3	GOBP_Ncrna_Processing	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Lage3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Lage3	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Lage3	GOBP_Trna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Lage3	GOBP_Trna_Processing	Mouse	Spinal cord	L7CN47_C1	3.7e-07
Lage3	GOBP_Trna_Processing	Mouse	Brain	rep_27	1.9e-07
Lage3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_1	2.5e-12
Lage3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_1	1.6e-17
Lage3	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	rep_3	1.8e-46
Lage3	GOBP_Ncrna_Processing	Mouse	Brain	rep_3	5.1e-21
Lage3	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Lage3	GOBP_Trna_Metabolic_Process	Mouse	Brain	rep_3	2.5e-229
Lage3	GOBP_Trna_Processing	Mouse	Brain	rep_3	7.2e-211
Lage3	GOBP_Trna_Threonylcarbamoyladenosine_Metabolic_Process	Mouse	Brain	rep_3	4.7e-97
Lage3	GOBP_Ncrna_Processing	Mouse	Embryo	rep_14	2.7e-41
Lage3	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Lage3	GOBP_Trna_Processing	Mouse	Embryo	rep_14	1.5e-48
Lage3	GOBP_Trna_Threonylcarbamoyladenosine_Metabolic_Process	Mouse	Embryo	rep_14	2.1e-15
Lage3	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Lage3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Lage3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Lage3	GOBP_Ncrna_Metabolic_Process	Mouse	Kidney	rep_2	6.2e-81
Lage3	GOBP_Ncrna_Processing	Mouse	Kidney	rep_2	5.7e-81
Lage3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	4.5e-10
Lage3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	8.3e-40
Lage3	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Lage3	GOBP_Trna_Metabolic_Process	Mouse	Kidney	rep_2	1.9e-92
Lage3	GOBP_Trna_Processing	Mouse	Kidney	rep_2	1.3e-62
Lage3	GOBP_Trna_Threonylcarbamoyladenosine_Metabolic_Process	Mouse	Kidney	rep_2	1.6e-54
Lage3	GOBP_Trna_Threonylcarbamoyladenosine_Metabolic_Process	Mouse	Liver	CN16-E1	2.2e-09
Lage3	GOBP_Ncrna_Metabolic_Process	Mouse	Liver	CN73-C1	1.4e-08
Lage3	GOBP_Trna_Threonylcarbamoyladenosine_Metabolic_Process	Mouse	Liver	rep_23	6.3e-12
Lage3	GOBP_Ncrna_Metabolic_Process	Mouse	Lymph	MS-1	1.4e-09
Lage3	GOBP_Ncrna_Processing	Mouse	Lymph	MS-1	7.2e-09
Lage3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Lage3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	1.7e-12
Lage3	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Lage3	GOBP_Trna_Metabolic_Process	Mouse	Lymph	MS-1	1.0e-08
Lage3	GOBP_Trna_Processing	Mouse	Lymph	MS-1	7.9e-12
Lage3	GOBP_Trna_Threonylcarbamoyladenosine_Metabolic_Process	Mouse	Lymph	MS-1	4.3e-08
Lage3	GOBP_Trna_Metabolic_Process	Mouse	Brain	rep_4	2.6e-107
Lage3	GOBP_Trna_Processing	Mouse	Brain	rep_7	2.4e-14
Lage3	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-10
Lage3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-11
Lage3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.3e-11
Lage3	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Lage3	GOBP_Ncrna_Processing	Mouse	Brain	HP_adpolb_rep1	3.5e-08
Lage3	GOBP_Trna_Metabolic_Process	Mouse	Brain	HP_adpolb_rep5	9.9e-10
Lage3	GOBP_Trna_Threonylcarbamoyladenosine_Metabolic_Process	Mouse	Brain	HP_polb_rep9	3.5e-08

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Lage3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Lage3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Lage3 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Lage3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Lage3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source