|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: Ier3ip1 (spascer ID:66191) |
Gene summary for Ier3ip1 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Ier3ip1 | Gene ID | 66191 |
| Gene name | immediate early response 3 interacting protein 1 |
| Synonyms | 1110057H19Rik|AI644142|AL022842|AL022863|AV026606 |
| Cytomap | 18|18 E3 |
| Type of gene | protein-coding |
| Description | immediate early response 3-interacting protein 1 |
| Modification date | 20220424 |
| UniProtAcc | Q9CR20 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Ier3ip1 | GO:0005789 | endoplasmic reticulum membrane | 21873635 | Component |
| Ier3ip1 | GO:0006888 | endoplasmic reticulum to Golgi vesicle-mediated transport | 21873635 | Process |
| Ier3ip1 | GO:0030134 | COPII-coated ER to Golgi transport vesicle | 21873635 | Component |
| Ier3ip1 | GO:0030173 | integral component of Golgi membrane | 21873635 | Component |
Top |
Spatial pattern events for Ier3ip1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Ier3ip1 | Mouse | Kidney | IRI | 34003797 | 7.97e-08 |
| Ier3ip1 | Mouse | Brain | rep_1 | 33469025 | 5.79e-07 |
| Ier3ip1 | Mouse | Intestine | rep_4 | 35149721 | 2.30e-15 |
| Ier3ip1 | Mouse | Lung | rep_4 | 35290801 | 1.02e-14 |
| Ier3ip1 | Mouse | Brain | rep_7 | 35210624 | 2.52e-11 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_IRI_H&E  |  |
Brain_rep_1_H&E  | |
Lung_rep_4_H&E  |  |
Top |
Spatial pattern pathway has Ier3ip1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Ier3ip1 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Spinal cord | L7CN45_C1 | 7.4e-08 |
| Ier3ip1 | GOBP_Fibroblast_Apoptotic_Process | Mouse | Spinal cord | L7CN45_C1 | 9.8e-07 |
| Ier3ip1 | GOBP_Golgi_Vesicle_Transport | Mouse | Spinal cord | L7CN45_C1 | 3.6e-07 |
| Ier3ip1 | GOBP_Intracellular_Transport | Mouse | Spinal cord | L7CN45_C1 | 4.4e-06 |
| Ier3ip1 | GOBP_Golgi_Vesicle_Transport | Mouse | Brain | rep_27 | 5.1e-06 |
| Ier3ip1 | GOBP_Regulation_Of_Cell_Death | Mouse | Brain | rep_27 | 6.3e-05 |
| Ier3ip1 | GOBP_Golgi_Vesicle_Transport | Mouse | Brain | rep_1 | 1.2e-15 |
| Ier3ip1 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Brain | rep_3 | 7.6e-183 |
| Ier3ip1 | GOBP_Fibroblast_Apoptotic_Process | Mouse | Brain | rep_3 | 6.9e-154 |
| Ier3ip1 | GOBP_Intracellular_Transport | Mouse | Brain | rep_3 | 1.0e-102 |
| Ier3ip1 | GOBP_Regulation_Of_Cell_Death | Mouse | Brain | rep_3 | 7.6e-107 |
| Ier3ip1 | GOBP_Fibroblast_Apoptotic_Process | Mouse | Embryo | rep_6 | 3.0e-17 |
| Ier3ip1 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Embryo | rep_14 | 4.4e-33 |
| Ier3ip1 | GOBP_Golgi_Vesicle_Transport | Mouse | Embryo | rep_14 | 5.7e-09 |
| Ier3ip1 | GOBP_Regulation_Of_Cell_Death | Mouse | Embryo | rep_1 | 8.4e-30 |
| Ier3ip1 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Kidney | rep_2 | 1.8e-93 |
| Ier3ip1 | GOBP_Fibroblast_Apoptotic_Process | Mouse | Kidney | rep_2 | 2.1e-40 |
| Ier3ip1 | GOBP_Golgi_Vesicle_Transport | Mouse | Kidney | rep_2 | 6.5e-131 |
| Ier3ip1 | GOBP_Intracellular_Transport | Mouse | Kidney | rep_2 | 7.9e-80 |
| Ier3ip1 | GOBP_Fibroblast_Apoptotic_Process | Mouse | Liver | CN16-D2 | 1.9e-07 |
| Ier3ip1 | GOBP_Regulation_Of_Cell_Death | Mouse | Liver | rep_16 | 2.0e-13 |
| Ier3ip1 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Lymph | MS-1 | 4.3e-11 |
| Ier3ip1 | GOBP_Fibroblast_Apoptotic_Process | Mouse | Lymph | MS-1 | 3.3e-11 |
| Ier3ip1 | GOBP_Golgi_Vesicle_Transport | Mouse | Lymph | MS-1 | 5.2e-08 |
| Ier3ip1 | GOBP_Intracellular_Transport | Mouse | Lymph | MS-1 | 3.3e-11 |
| Ier3ip1 | GOBP_Regulation_Of_Cell_Death | Mouse | Lymph | MS-1 | 1.9e-12 |
| Ier3ip1 | GOBP_Endoplasmic_Reticulum_To_Golgi_Vesicle_Mediated_Transport | Mouse | Brain | HP_ad_rep7 | 6.3e-08 |
| Ier3ip1 | GOBP_Golgi_Vesicle_Transport | Mouse | Brain | HP_ad_rep7 | 1.1e-09 |
| Ier3ip1 | GOBP_Intracellular_Transport | Mouse | Brain | HP_ad_rep7 | 3.1e-08 |
| Ier3ip1 | GOBP_Regulation_Of_Cell_Death | Mouse | Brain | HP_ad_rep7 | 1.6e-07 |
| Ier3ip1 | GOBP_Fibroblast_Apoptotic_Process | Mouse | Brain | HP_adpolb_rep1 | 7.1e-07 |
Top |
Ier3ip1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
Ier3ip1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for Ier3ip1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for Ier3ip1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for Ier3ip1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Ier3ip1 | C3280240 | MICROCEPHALY, EPILEPSY, AND DIABETES SYNDROME | 3 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
| Ier3ip1 | C0158981 | Neonatal diabetes mellitus | 1 | GENOMICS_ENGLAND |
| Ier3ip1 | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND |
| Ier3ip1 | C4229700 | Microcephaly (-3 to -9 SD) | 1 | GENOMICS_ENGLAND |
