Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Nop10 (spascer ID:66181)

Gene summary for Nop10

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Nop10
	Gene ID	66181
	Gene name	NOP10 ribonucleoprotein
	Synonyms	1110036B12Rik\|NOP10P\|Nola3
	Cytomap	2\|2 E3
	Type of gene	protein-coding
	Description	H/ACA ribonucleoprotein complex subunit 3H/ACA small nucleolar RNPsNOP10 ribonucleoprotein homolognucleolar protein 10nucleolar protein family A, member 3snoRNP protein NOP10
	Modification date	20220424
	UniProtAcc	Q9CQS2

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Nop10	GO:0031118	rRNA pseudouridine synthesis	21873635	Process
Nop10	GO:0031120	snRNA pseudouridine synthesis	21873635	Process
Nop10	GO:0031429	box H/ACA snoRNP complex	21873635	Component
Nop10	GO:0034513	box H/ACA snoRNA binding	21873635	Function
Nop10	GO:0070034	telomerase RNA binding	21873635	Function
Nop10	GO:0090661	box H/ACA telomerase RNP complex	21873635	Component

Top

Spatial pattern events for Nop10

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Nop10	Mouse	Brain	S1	34413515	2.07e-15
Nop10	Mouse	Brain	S2	34413515	1.56e-15
Nop10	Mouse	Brain	S3	34413515	1.64e-15
Nop10	Mouse	Brain	S4	34413515	1.37e-15
Nop10	Mouse	Brain	S6	34413515	1.46e-15
Nop10	Mouse	Brain	S7	34413515	1.55e-15
Nop10	Mouse	Brain	rep_1	35141374	2.22e-09
Nop10	Mouse	Brain	rep_2	35141374	1.69e-15
Nop10	Mouse	Brain	rep_3	35141374	1.64e-15
Nop10	Mouse	Brain	rep_4	35141374	1.57e-15
Nop10	Mouse	Brain	rep_5	35141374	1.47e-15
Nop10	Mouse	Brain	rep_6	35141374	5.96e-15
Nop10	Mouse	Embryo	rep_12	33188776	4.79e-06
Nop10	Mouse	Kidney	CLP	34003797	2.19e-15
Nop10	Mouse	Kidney	IRI	34003797	6.07e-09
Nop10	Mouse	Kidney	Sham	34003797	2.58e-15
Nop10	Mouse	Kidney	rep_1	34853151	2.42e-15
Nop10	Mouse	Kidney	rep_3	34853151	4.93e-15
Nop10	Mouse	Kidney	rep_4	34853151	1.26e-14
Nop10	Mouse	Kidney	rep_5	34853151	3.18e-15
Nop10	Mouse	Brain	rep_1	33469025	1.30e-15
Nop10	Mouse	Liver	rep_19	35021063	1.49e-08
Nop10	Mouse	Liver	rep_20	35021063	5.41e-12
Nop10	Mouse	Liver	rep_21	35021063	8.03e-15
Nop10	Mouse	Liver	rep_22	35021063	1.74e-14
Nop10	Mouse	Liver	rep_23	35021063	2.29e-14
Nop10	Mouse	Brain	rep_1	35027729	1.66e-15
Nop10	Mouse	Brain	rep_2	35027729	1.57e-15
Nop10	Mouse	Brain	rep_3	35027729	1.32e-15
Nop10	Mouse	Brain	rep_4	35027729	1.76e-15
Nop10	Mouse	Brain	rep_5	35027729	1.46e-15
Nop10	Mouse	Intestine	rep_2	35149721	1.34e-07
Nop10	Mouse	Intestine	rep_3	35149721	9.60e-15
Nop10	Mouse	Intestine	rep_4	35149721	1.11e-09
Nop10	Mouse	Brain	B05_D2	32702314	1.34e-06
Nop10	Mouse	Testicle	rep_1	34731600	3.23e-15
Nop10	Mouse	Lymph	A1	0	3.29e-15
Nop10	Mouse	Lymph	B1	0	1.86e-11
Nop10	Mouse	Lung	rep_1	35290801	3.28e-13
Nop10	Mouse	Lung	rep_2	35290801	7.23e-15
Nop10	Mouse	Lung	rep_3	35290801	8.40e-15
Nop10	Mouse	Lung	rep_4	35290801	1.02e-14
Nop10	Mouse	Brain	rep_1	35210624	1.74e-15
Nop10	Mouse	Brain	rep_2	35210624	1.74e-15
Nop10	Mouse	Brain	rep_3	35210624	1.82e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_19_H&E
Liver_rep_20_H&E
Liver_rep_21_H&E
Liver_rep_22_H&E
Liver_rep_23_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B05_D2_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E

Top

Spatial pattern pathway has Nop10 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Nop10	GOBP_Anatomical_Structure_Homeostasis	Mouse	Spinal cord	CN94_E1	6.4e-06
Nop10	GOBP_Dna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	2.7e-06
Nop10	GOBP_Rna_Localization	Mouse	Spinal cord	CN94_E1	3.7e-06
Nop10	GOBP_Telomere_Maintenance_Via_Telomere_Lengthening	Mouse	Spinal cord	CN94_E1	3.9e-06
Nop10	GOBP_Snrna_Modification	Mouse	Spinal cord	L7CN30_D2	4.1e-07
Nop10	GOBP_Pseudouridine_Synthesis	Mouse	Spinal cord	L7CN44_C1	7.0e-08
Nop10	GOBP_Chromosome_Organization	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Nop10	GOBP_Homeostatic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Nop10	GOBP_Ncrna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.5e-07
Nop10	GOBP_Ncrna_Processing	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Nop10	GOBP_Positive_Regulation_Of_Telomerase_Rna_Localization_To_Cajal_Body	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Nop10	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Nop10	GOBP_Ribosome_Biogenesis	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Nop10	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Nop10	GOBP_Rrna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.3e-07
Nop10	GOBP_Rrna_Modification	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Nop10	GOBP_Rrna_Pseudouridine_Synthesis	Mouse	Spinal cord	L7CN45_C1	6.3e-07
Nop10	GOBP_Snrna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	7.1e-06
Nop10	GOBP_Telomerase_Rna_Localization	Mouse	Spinal cord	L7CN45_C1	3.0e-08
Nop10	GOBP_Rna_Modification	Mouse	Spinal cord	L8CN17_E1	4.8e-08
Nop10	GOBP_Pseudouridine_Synthesis	Mouse	Brain	rep_27	1.6e-05
Nop10	GOBP_Rna_Dependent_Dna_Biosynthetic_Process	Mouse	Brain	rep_27	2.1e-06
Nop10	GOBP_Rrna_Modification	Mouse	Brain	rep_27	3.6e-05
Nop10	GOBP_Rrna_Pseudouridine_Synthesis	Mouse	Brain	rep_27	3.6e-09
Nop10	GOBP_Telomere_Maintenance_Via_Telomere_Lengthening	Mouse	Brain	rep_75	7.7e-05
Nop10	GOBP_Chromosome_Organization	Mouse	Brain	rep_1	3.9e-07
Nop10	GOBP_Dna_Metabolic_Process	Mouse	Brain	rep_1	1.1e-07
Nop10	GOBP_Pseudouridine_Synthesis	Mouse	Brain	rep_1	1.6e-10
Nop10	GOBP_Rna_Dependent_Dna_Biosynthetic_Process	Mouse	Brain	rep_1	7.3e-12
Nop10	GOBP_Rrna_Modification	Mouse	Brain	rep_1	6.7e-09
Nop10	GOBP_Rrna_Pseudouridine_Synthesis	Mouse	Brain	rep_1	8.1e-10
Nop10	GOBP_Snrna_Metabolic_Process	Mouse	Brain	rep_1	5.9e-22
Nop10	GOBP_Telomere_Maintenance_Via_Telomere_Lengthening	Mouse	Brain	rep_1	5.7e-08
Nop10	GOBP_Telomere_Organization	Mouse	Brain	rep_1	8.3e-12
Nop10	GOBP_Anatomical_Structure_Homeostasis	Mouse	Brain	rep_3	1.8e-76
Nop10	GOBP_Dna_Biosynthetic_Process	Mouse	Brain	rep_3	1.9e-141
Nop10	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	rep_3	1.8e-46
Nop10	GOBP_Ncrna_Processing	Mouse	Brain	rep_3	5.1e-21
Nop10	GOBP_Positive_Regulation_Of_Telomerase_Rna_Localization_To_Cajal_Body	Mouse	Brain	rep_3	2.0e-196
Nop10	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Brain	rep_3	5.6e-32
Nop10	GOBP_Ribosome_Biogenesis	Mouse	Brain	rep_3	1.8e-14
Nop10	GOBP_Rna_Localization	Mouse	Brain	rep_3	6.0e-194
Nop10	GOBP_Rna_Modification	Mouse	Brain	rep_3	1.8e-211
Nop10	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Nop10	GOBP_Rrna_Metabolic_Process	Mouse	Brain	rep_3	1.7e-24
Nop10	GOBP_Snrna_Modification	Mouse	Brain	rep_3	1.7e-191
Nop10	GOBP_Telomerase_Rna_Localization	Mouse	Brain	rep_3	5.6e-168
Nop10	GOBP_Homeostatic_Process	Mouse	Brain	rep_7	2.5e-13
Nop10	GOBP_Pseudouridine_Synthesis	Mouse	Embryo	rep_6	2.7e-07
Nop10	GOBP_Rrna_Pseudouridine_Synthesis	Mouse	Embryo	rep_6	1.5e-09
Nop10	GOBP_Snrna_Modification	Mouse	Embryo	rep_6	5.2e-21
Nop10	GOBP_Dna_Biosynthetic_Process	Mouse	Embryo	rep_14	9.7e-10
Nop10	GOBP_Ncrna_Processing	Mouse	Embryo	rep_14	2.7e-41
Nop10	GOBP_Positive_Regulation_Of_Telomerase_Rna_Localization_To_Cajal_Body	Mouse	Embryo	rep_14	5.2e-89
Nop10	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Embryo	rep_14	2.1e-33
Nop10	GOBP_Ribosome_Biogenesis	Mouse	Embryo	rep_14	2.1e-33
Nop10	GOBP_Rna_Dependent_Dna_Biosynthetic_Process	Mouse	Embryo	rep_14	2.7e-25
Nop10	GOBP_Rna_Localization	Mouse	Embryo	rep_14	4.6e-13
Nop10	GOBP_Rna_Modification	Mouse	Embryo	rep_14	3.1e-46
Nop10	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Nop10	GOBP_Rrna_Metabolic_Process	Mouse	Embryo	rep_14	2.2e-54
Nop10	GOBP_Rrna_Modification	Mouse	Embryo	rep_14	1.3e-64
Nop10	GOBP_Snrna_Metabolic_Process	Mouse	Embryo	rep_14	1.2e-45
Nop10	GOBP_Telomerase_Rna_Localization	Mouse	Embryo	rep_14	2.4e-63
Nop10	GOBP_Telomere_Maintenance_Via_Telomere_Lengthening	Mouse	Embryo	rep_14	5.5e-08
Nop10	GOBP_Telomere_Organization	Mouse	Embryo	rep_14	1.1e-09
Nop10	GOBP_Homeostatic_Process	Mouse	Embryo	rep_1	2.0e-30
Nop10	GOBP_Telomere_Organization	Mouse	Embryo	rep_1	9.8e-111
Nop10	GOBP_Dna_Metabolic_Process	Mouse	Embryo	rep_2	7.2e-216
Nop10	GOBP_Rna_Localization	Mouse	Embryo	rep_2	4.2e-15
Nop10	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Nop10	GOBP_Chromosome_Organization	Mouse	Embryo	rep_3	1.4e-57
Nop10	GOBP_Anatomical_Structure_Homeostasis	Mouse	Kidney	rep_2	8.4e-22
Nop10	GOBP_Chromosome_Organization	Mouse	Kidney	rep_2	1.0e-14
Nop10	GOBP_Dna_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-12
Nop10	GOBP_Homeostatic_Process	Mouse	Kidney	rep_2	2.2e-10
Nop10	GOBP_Ncrna_Metabolic_Process	Mouse	Kidney	rep_2	6.2e-81
Nop10	GOBP_Ncrna_Processing	Mouse	Kidney	rep_2	5.7e-81
Nop10	GOBP_Positive_Regulation_Of_Telomerase_Rna_Localization_To_Cajal_Body	Mouse	Kidney	rep_2	6.5e-59
Nop10	GOBP_Pseudouridine_Synthesis	Mouse	Kidney	rep_2	7.2e-31
Nop10	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Kidney	rep_2	1.3e-69
Nop10	GOBP_Ribosome_Biogenesis	Mouse	Kidney	rep_2	2.5e-90
Nop10	GOBP_Rna_Localization	Mouse	Kidney	rep_2	1.1e-66
Nop10	GOBP_Rna_Modification	Mouse	Kidney	rep_2	7.1e-48
Nop10	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Nop10	GOBP_Rrna_Metabolic_Process	Mouse	Kidney	rep_2	6.8e-87
Nop10	GOBP_Rrna_Modification	Mouse	Kidney	rep_2	5.6e-14
Nop10	GOBP_Rrna_Pseudouridine_Synthesis	Mouse	Kidney	rep_2	9.3e-31
Nop10	GOBP_Snrna_Metabolic_Process	Mouse	Kidney	rep_2	1.1e-47
Nop10	GOBP_Telomerase_Rna_Localization	Mouse	Kidney	rep_2	2.1e-45
Nop10	GOBP_Positive_Regulation_Of_Telomerase_Rna_Localization_To_Cajal_Body	Mouse	Liver	CN16-D1	1.9e-09
Nop10	GOBP_Dna_Metabolic_Process	Mouse	Liver	CN16-D2	2.6e-07
Nop10	GOBP_Telomerase_Rna_Localization	Mouse	Liver	CN16-D2	7.3e-10
Nop10	GOBP_Pseudouridine_Synthesis	Mouse	Liver	CN16-E1	3.6e-09
Nop10	GOBP_Ncrna_Metabolic_Process	Mouse	Liver	CN73-C1	1.4e-08
Nop10	GOBP_Anatomical_Structure_Homeostasis	Mouse	Liver	rep_16	8.1e-23
Nop10	GOBP_Pseudouridine_Synthesis	Mouse	Liver	rep_23	7.0e-08
Nop10	GOBP_Rrna_Pseudouridine_Synthesis	Mouse	Liver	rep_23	6.5e-25
Nop10	GOBP_Rrna_Pseudouridine_Synthesis	Mouse	Intestine	rep_3	4.6e-19
Nop10	GOBP_Anatomical_Structure_Homeostasis	Mouse	Lymph	MS-1	1.1e-14
Nop10	GOBP_Chromosome_Organization	Mouse	Lymph	MS-1	3.5e-09
Nop10	GOBP_Dna_Metabolic_Process	Mouse	Lymph	MS-1	6.8e-10
Nop10	GOBP_Homeostatic_Process	Mouse	Lymph	MS-1	2.3e-12
Nop10	GOBP_Ncrna_Metabolic_Process	Mouse	Lymph	MS-1	1.4e-09
Nop10	GOBP_Ncrna_Processing	Mouse	Lymph	MS-1	7.2e-09
Nop10	GOBP_Positive_Regulation_Of_Telomerase_Rna_Localization_To_Cajal_Body	Mouse	Lymph	MS-1	5.2e-08
Nop10	GOBP_Pseudouridine_Synthesis	Mouse	Lymph	MS-1	2.2e-08
Nop10	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Lymph	MS-1	1.7e-07
Nop10	GOBP_Ribosome_Biogenesis	Mouse	Lymph	MS-1	8.8e-09
Nop10	GOBP_Rna_Dependent_Dna_Biosynthetic_Process	Mouse	Lymph	MS-1	3.4e-09
Nop10	GOBP_Rna_Modification	Mouse	Lymph	MS-1	9.8e-15
Nop10	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Nop10	GOBP_Rrna_Metabolic_Process	Mouse	Lymph	MS-1	7.1e-07
Nop10	GOBP_Rrna_Pseudouridine_Synthesis	Mouse	Lymph	MS-1	1.5e-08
Nop10	GOBP_Snrna_Metabolic_Process	Mouse	Lymph	MS-1	2.5e-07
Nop10	GOBP_Snrna_Modification	Mouse	Lymph	MS-1	1.4e-11
Nop10	GOBP_Telomerase_Rna_Localization	Mouse	Lymph	MS-1	3.0e-07
Nop10	GOBP_Telomere_Maintenance_Via_Telomere_Lengthening	Mouse	Lymph	MS-1	3.1e-07
Nop10	GOBP_Telomere_Organization	Mouse	Lymph	MS-1	1.9e-10
Nop10	GOBP_Rna_Modification	Mouse	Brain	rep_7	3.9e-16
Nop10	GOBP_Rrna_Modification	Mouse	Brain	rep_7	2.4e-36
Nop10	GOBP_Snrna_Metabolic_Process	Mouse	Brain	rep_7	2.0e-29
Nop10	GOBP_Snrna_Modification	Mouse	Brain	HP_ad_rep3	1.1e-08
Nop10	GOBP_Chromosome_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Nop10	GOBP_Dna_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	1.2e-12
Nop10	GOBP_Dna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-11
Nop10	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-10
Nop10	GOBP_Pseudouridine_Synthesis	Mouse	Brain	HP_ad_rep7	9.9e-08
Nop10	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Brain	HP_ad_rep7	7.9e-07
Nop10	GOBP_Ribosome_Biogenesis	Mouse	Brain	HP_ad_rep7	1.6e-08
Nop10	GOBP_Rna_Dependent_Dna_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	1.0e-07
Nop10	GOBP_Rna_Localization	Mouse	Brain	HP_ad_rep7	8.4e-16
Nop10	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Nop10	GOBP_Rrna_Modification	Mouse	Brain	HP_ad_rep7	3.0e-08
Nop10	GOBP_Snrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.2e-13
Nop10	GOBP_Telomerase_Rna_Localization	Mouse	Brain	HP_ad_rep7	1.5e-07
Nop10	GOBP_Telomere_Organization	Mouse	Brain	HP_ad_rep7	9.3e-09
Nop10	GOBP_Rrna_Pseudouridine_Synthesis	Mouse	Brain	HP_ad_rep8	8.5e-11
Nop10	GOBP_Ncrna_Processing	Mouse	Brain	HP_adpolb_rep1	3.5e-08
Nop10	GOBP_Positive_Regulation_Of_Telomerase_Rna_Localization_To_Cajal_Body	Mouse	Brain	HP_adpolb_rep1	1.3e-10
Nop10	GOBP_Rna_Modification	Mouse	Brain	HP_adpolb_rep1	5.1e-09
Nop10	GOBP_Rrna_Metabolic_Process	Mouse	Brain	HP_adpolb_rep1	2.6e-13
Nop10	GOBP_Telomere_Maintenance_Via_Telomere_Lengthening	Mouse	Brain	HP_adpolb_rep1	1.6e-08
Nop10	GOBP_Homeostatic_Process	Mouse	Brain	HP_polb_rep9	6.4e-11

Top

Nop10 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

Nop10 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for Nop10 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for Nop10

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for Nop10

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Nop10	C0265965	Dyskeratosis Congenita	3	GENOMICS_ENGLAND
Nop10	C1846142	HOYERAAL-HREIDARSSON SYNDROME	1	GENOMICS_ENGLAND
Nop10	C1857144	DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE 1	1	GENOMICS_ENGLAND;UNIPROT