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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Med11 (spascer ID:66172)

Gene summary for Med11

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Med11

Gene ID

66172

Gene namemediator complex subunit 11
Synonyms1110030J09Rik|AI465144|AW545069
Cytomap11|11 B3
Type of geneprotein-coding
Descriptionmediator of RNA polymerase II transcription subunit 11mediator of RNA polymerase II transcription, subunit 11 homolog
Modification date20220424
UniProtAcc

Q9D8C6


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Med11

GO:0016592

mediator complex

21873635

Component

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Spatial pattern events for Med11

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Med11MouseKidneyCLP 340037972.19e-15
Med11MouseKidneySham 340037977.70e-12
Med11MouseLymphA1 01.50e-09
Med11MouseLymphB1 06.08e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_CLP_H&E
boxplot

boxplot
Kidney_Sham_H&E
boxplot

boxplot


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Spatial pattern pathway has Med11 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Med11GOBP_Protein_Modification_By_Small_Protein_ConjugationMouseSpinal cordL7CN45_C1 2.2e-07
Med11GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_RemovalMouseSpinal cordL7CN45_C1 1.4e-06
Med11GOBP_Protein_Modification_By_Small_Protein_ConjugationMouseBrainrep_31.4e-184
Med11GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_RemovalMouseBrainrep_36.3e-190
Med11GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_RemovalMouseEmbryorep_1 4.4e-16
Med11GOBP_Protein_Modification_By_Small_Protein_ConjugationMouseEmbryorep_3 4.2e-21
Med11GOBP_Protein_Modification_By_Small_Protein_ConjugationMouseLymphMS-1 1.4e-09
Med11GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_RemovalMouseLymphMS-1 1.4e-09
Med11GOBP_Protein_Modification_By_Small_Protein_ConjugationMouseBrainHP_ad_rep7 1.7e-09
Med11GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_RemovalMouseBrainHP_ad_rep7 6.9e-09

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Med11 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Med11 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Med11 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Med11

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Med11

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource