Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Pgls (spascer ID:66171)

Gene summary for Pgls

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Pgls
	Gene ID	66171
	Gene name	6-phosphogluconolactonase
	Synonyms	1110030K05Rik\|AI447866\|Plgs
	Cytomap	8 B3.3\|8
	Type of gene	protein-coding
	Description	6-phosphogluconolactonase6PGL
	Modification date	20220424
	UniProtAcc	Q9CQ60

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Pgls	GO:0005737	cytoplasm	21873635	Component
Pgls	GO:0009051	pentose-phosphate shunt, oxidative branch	21873635	Process
Pgls	GO:0017057	6-phosphogluconolactonase activity	21873635	Function

Top

Spatial pattern events for Pgls

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Pgls	Mouse	Brain	S2	34413515	6.58e-13
Pgls	Mouse	Brain	S4	34413515	7.57e-09
Pgls	Mouse	Brain	rep_1	35141374	2.70e-09
Pgls	Mouse	Brain	rep_2	35141374	6.26e-10
Pgls	Mouse	Brain	rep_4	35141374	5.42e-15
Pgls	Mouse	Brain	rep_5	35141374	2.68e-15
Pgls	Mouse	Brain	rep_6	35141374	5.02e-08
Pgls	Mouse	Kidney	IRI	34003797	1.52e-07
Pgls	Mouse	Kidney	Sham	34003797	5.68e-09
Pgls	Mouse	Kidney	rep_1	34853151	2.42e-15
Pgls	Mouse	Kidney	rep_2	34853151	1.04e-07
Pgls	Mouse	Kidney	rep_4	34853151	4.07e-15
Pgls	Mouse	Kidney	rep_5	34853151	5.84e-09
Pgls	Mouse	Brain	rep_1	33469025	2.37e-15
Pgls	Mouse	Brain	rep_3	35027729	1.32e-15
Pgls	Mouse	Brain	rep_4	35027729	5.17e-08
Pgls	Mouse	Brain	rep_5	35027729	9.18e-13
Pgls	Mouse	Intestine	rep_2	35149721	9.49e-07
Pgls	Mouse	Intestine	rep_3	35149721	5.21e-15
Pgls	Mouse	Intestine	rep_4	35149721	2.30e-15
Pgls	Mouse	Lymph	A1	0	3.29e-15
Pgls	Mouse	Lymph	B1	0	3.66e-15
Pgls	Mouse	Lung	rep_1	35290801	4.52e-15
Pgls	Mouse	Lung	rep_2	35290801	2.44e-11
Pgls	Mouse	Brain	rep_1	35210624	1.74e-15
Pgls	Mouse	Brain	rep_2	35210624	8.75e-11
Pgls	Mouse	Brain	rep_3	35210624	1.82e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E

Top

Spatial pattern pathway has Pgls envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Pgls	GOBP_Glucose_6_Phosphate_Metabolic_Process	Mouse	Spinal cord	L7bCN01_D2	1.1e-06
Pgls	GOBP_Nadph_Regeneration	Mouse	Spinal cord	L7CN32_C1	3.0e-07
Pgls	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Pgls	GOBP_Carbohydrate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-08
Pgls	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Spinal cord	L7CN45_C1	2.2e-08
Pgls	GOBP_Nadp_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.5e-06
Pgls	GOBP_Organophosphate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Pgls	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	rep_71	2.1e-06
Pgls	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	rep_1	5.4e-15
Pgls	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Pgls	GOBP_Carbohydrate_Metabolic_Process	Mouse	Brain	rep_3	1.4e-74
Pgls	GOBP_Glucose_6_Phosphate_Metabolic_Process	Mouse	Brain	rep_3	4.8e-142
Pgls	GOBP_Nadp_Metabolic_Process	Mouse	Brain	rep_3	2.7e-81
Pgls	GOBP_Nadph_Regeneration	Mouse	Brain	rep_3	2.4e-69
Pgls	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	rep_3	8.1e-43
Pgls	GOBP_Carbohydrate_Metabolic_Process	Mouse	Embryo	rep_14	1.1e-08
Pgls	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Embryo	rep_14	2.9e-37
Pgls	GOBP_Glucose_6_Phosphate_Metabolic_Process	Mouse	Embryo	rep_14	1.1e-75
Pgls	GOBP_Nadp_Metabolic_Process	Mouse	Embryo	rep_14	1.1e-63
Pgls	GOBP_Nadph_Regeneration	Mouse	Embryo	rep_14	2.0e-59
Pgls	GOBP_Organophosphate_Metabolic_Process	Mouse	Embryo	rep_14	2.0e-09
Pgls	GOBP_Carbohydrate_Metabolic_Process	Mouse	Embryo	rep_1	5.6e-24
Pgls	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Pgls	GOBP_Carbohydrate_Metabolic_Process	Mouse	Kidney	rep_2	5.2e-99
Pgls	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Kidney	rep_2	3.3e-14
Pgls	GOBP_Glucose_6_Phosphate_Metabolic_Process	Mouse	Kidney	rep_2	3.6e-131
Pgls	GOBP_Nadp_Metabolic_Process	Mouse	Kidney	rep_2	1.3e-104
Pgls	GOBP_Nadph_Regeneration	Mouse	Kidney	rep_2	1.4e-88
Pgls	GOBP_Organophosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-41
Pgls	GOBP_Nadp_Metabolic_Process	Mouse	Liver	CN16-E1	1.9e-08
Pgls	GOBP_Nadph_Regeneration	Mouse	Liver	CN65-C1	6.3e-07
Pgls	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Pgls	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Liver	rep_16	7.4e-11
Pgls	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Pgls	GOBP_Carbohydrate_Metabolic_Process	Mouse	Lymph	MS-1	5.9e-10
Pgls	GOBP_Organophosphate_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-07
Pgls	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Pgls	GOBP_Carbohydrate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.6e-09
Pgls	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	HP_polb_rep9	5.4e-11
Pgls	GOBP_Glucose_6_Phosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.2e-10
Pgls	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	7.1e-09

Top

Pgls function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

Pgls function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for Pgls envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for Pgls

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for Pgls

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Pgls	C0001787	Osteoporosis, Age-Related	1	CTD_human
Pgls	C0029456	Osteoporosis	1	CTD_human
Pgls	C0029459	Osteoporosis, Senile	1	CTD_human
Pgls	C0751406	Post-Traumatic Osteoporosis	1	CTD_human