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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Bola2 (spascer ID:66162)

Gene summary for Bola2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Bola2
	Gene ID	66162
	Gene name	bolA-like 2 (E. coli)
	Synonyms	1110025L05Rik\|BolA-2
	Cytomap	7\|7 F3
	Type of gene	protein-coding
	Description	bolA-like protein 2
	Modification date	20220424
	UniProtAcc	Q8BGS2

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Bola2	GO:0005634	nucleus	21873635	Component
Bola2	GO:0005829	cytosol	21873635	Component
Bola2	GO:0006879	cellular iron ion homeostasis	21873635	Process
Bola2	GO:0051536	iron-sulfur cluster binding	21873635	Function

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Spatial pattern events for Bola2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Bola2	Mouse	Brain	S1	34413515	7.10e-15
Bola2	Mouse	Brain	S3	34413515	2.96e-15
Bola2	Mouse	Brain	S4	34413515	2.43e-15
Bola2	Mouse	Brain	S6	34413515	1.46e-15
Bola2	Mouse	Brain	S7	34413515	1.55e-15
Bola2	Mouse	Brain	28B	32637622	5.61e-11
Bola2	Mouse	Brain	rep_1	35141374	1.18e-12
Bola2	Mouse	Brain	rep_2	35141374	1.69e-15
Bola2	Mouse	Brain	rep_3	35141374	1.64e-15
Bola2	Mouse	Brain	rep_4	35141374	1.57e-15
Bola2	Mouse	Brain	rep_5	35141374	1.47e-15
Bola2	Mouse	Brain	rep_6	35141374	1.73e-15
Bola2	Mouse	Embryo	rep_12	33188776	8.89e-10
Bola2	Mouse	Kidney	IRI	34003797	3.92e-15
Bola2	Mouse	Kidney	Sham	34003797	2.58e-15
Bola2	Mouse	Kidney	rep_1	34853151	2.42e-15
Bola2	Mouse	Kidney	rep_4	34853151	1.28e-10
Bola2	Mouse	Kidney	rep_5	34853151	6.41e-08
Bola2	Mouse	Brain	rep_1	33469025	4.48e-08
Bola2	Mouse	Liver	rep_21	35021063	8.55e-11
Bola2	Mouse	Brain	rep_1	35027729	1.91e-11
Bola2	Mouse	Brain	rep_2	35027729	1.57e-15
Bola2	Mouse	Brain	rep_3	35027729	1.32e-15
Bola2	Mouse	Brain	rep_4	35027729	1.20e-08
Bola2	Mouse	Brain	rep_5	35027729	1.52e-12
Bola2	Mouse	Lymph	A1	0	1.88e-08
Bola2	Mouse	Lung	rep_1	35290801	1.94e-13
Bola2	Mouse	Lung	rep_2	35290801	8.75e-15
Bola2	Mouse	Lung	rep_3	35290801	5.16e-07
Bola2	Mouse	Brain	rep_3	35210624	1.56e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_21_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E

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Spatial pattern pathway has Bola2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Bola2	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	3.0e-06
Bola2	GOBP_Protein_Maturation	Mouse	Spinal cord	CN94_E1	2.2e-06
Bola2	GOBP_Cellular_Homeostasis	Mouse	Spinal cord	L7CN45_C1	5.7e-08
Bola2	GOBP_Cellular_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	3.1e-08
Bola2	GOBP_Cellular_Iron_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	1.2e-06
Bola2	GOBP_Chemical_Homeostasis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Bola2	GOBP_Homeostatic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Bola2	GOBP_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	1.4e-08
Bola2	GOBP_Iron_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	1.2e-06
Bola2	GOBP_Metal_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	3.0e-08
Bola2	GOBP_Response_To_Cytokine	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Bola2	GOBP_Response_To_Interleukin_12	Mouse	Spinal cord	L7CN45_C1	4.7e-06
Bola2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.4e-07
Bola2	GOBP_2fe_2s_Cluster_Assembly	Mouse	Spinal cord	L7CN47_D1	4.9e-06
Bola2	GOBP_Protein_Maturation_By_Iron_Sulfur_Cluster_Transfer	Mouse	Spinal cord	L7CN47_D1	1.1e-06
Bola2	GOBP_Cellular_Homeostasis	Mouse	Brain	rep_71	6.9e-06
Bola2	GOBP_Cellular_Ion_Homeostasis	Mouse	Brain	rep_71	9.0e-05
Bola2	GOBP_Chemical_Homeostasis	Mouse	Brain	rep_71	8.4e-05
Bola2	GOBP_Ion_Homeostasis	Mouse	Brain	rep_71	9.0e-05
Bola2	GOBP_Metal_Ion_Homeostasis	Mouse	Brain	rep_71	4.0e-05
Bola2	GOBP_Protein_Maturation_By_Iron_Sulfur_Cluster_Transfer	Mouse	Brain	rep_71	8.1e-05
Bola2	GOBP_Response_To_Interleukin_12	Mouse	Brain	rep_1	9.0e-22
Bola2	GOBP_2fe_2s_Cluster_Assembly	Mouse	Brain	rep_3	1.1e-61
Bola2	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	rep_3	4.9e-10
Bola2	GOBP_Iron_Sulfur_Cluster_Assembly	Mouse	Brain	rep_3	2.0e-131
Bola2	GOBP_Protein_Maturation	Mouse	Brain	rep_3	1.1e-160
Bola2	GOBP_Protein_Maturation_By_Iron_Sulfur_Cluster_Transfer	Mouse	Brain	rep_3	4.9e-74
Bola2	GOBP_Response_To_Cytokine	Mouse	Brain	rep_3	1.2e-08
Bola2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Brain	rep_3	1.4e-160
Bola2	GOBP_Homeostatic_Process	Mouse	Brain	rep_7	2.5e-13
Bola2	GOBP_Iron_Sulfur_Cluster_Assembly	Mouse	Embryo	rep_6	9.3e-08
Bola2	GOBP_Response_To_Interleukin_12	Mouse	Embryo	rep_6	4.6e-07
Bola2	GOBP_2fe_2s_Cluster_Assembly	Mouse	Embryo	rep_14	9.2e-17
Bola2	GOBP_Cellular_Iron_Ion_Homeostasis	Mouse	Embryo	rep_14	7.8e-57
Bola2	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Mouse	Embryo	rep_14	3.2e-34
Bola2	GOBP_Iron_Ion_Homeostasis	Mouse	Embryo	rep_14	2.7e-38
Bola2	GOBP_Protein_Maturation	Mouse	Embryo	rep_14	6.3e-10
Bola2	GOBP_Protein_Maturation_By_Iron_Sulfur_Cluster_Transfer	Mouse	Embryo	rep_14	2.2e-21
Bola2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Embryo	rep_14	5.8e-13
Bola2	GOBP_Transition_Metal_Ion_Homeostasis	Mouse	Embryo	rep_14	2.1e-32
Bola2	GOBP_Homeostatic_Process	Mouse	Embryo	rep_1	2.0e-30
Bola2	GOBP_Response_To_Cytokine	Mouse	Embryo	rep_1	8.2e-211
Bola2	GOBP_Metal_Ion_Homeostasis	Mouse	Embryo	rep_3	2.5e-10
Bola2	GOBP_Protein_Maturation	Mouse	Kidney	IRI	2.5e-33
Bola2	GOBP_2fe_2s_Cluster_Assembly	Mouse	Kidney	rep_2	1.3e-79
Bola2	GOBP_Cellular_Iron_Ion_Homeostasis	Mouse	Kidney	rep_2	2.5e-29
Bola2	GOBP_Homeostatic_Process	Mouse	Kidney	rep_2	2.2e-10
Bola2	GOBP_Iron_Ion_Homeostasis	Mouse	Kidney	rep_2	8.4e-17
Bola2	GOBP_Iron_Sulfur_Cluster_Assembly	Mouse	Kidney	rep_2	8.3e-88
Bola2	GOBP_Protein_Maturation	Mouse	Kidney	rep_2	5.4e-103
Bola2	GOBP_Protein_Maturation_By_Iron_Sulfur_Cluster_Transfer	Mouse	Kidney	rep_2	1.9e-82
Bola2	GOBP_Response_To_Cytokine	Mouse	Kidney	rep_2	3.1e-14
Bola2	GOBP_Response_To_Interleukin_12	Mouse	Kidney	rep_2	4.1e-43
Bola2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Kidney	rep_2	8.6e-17
Bola2	GOBP_Response_To_Interleukin_12	Mouse	Liver	CN16-D2	2.0e-07
Bola2	GOBP_2fe_2s_Cluster_Assembly	Mouse	Liver	CN65-C1	7.6e-08
Bola2	GOBP_2fe_2s_Cluster_Assembly	Mouse	Liver	rep_15	3.7e-19
Bola2	GOBP_Cellular_Iron_Ion_Homeostasis	Mouse	Liver	rep_16	4.6e-14
Bola2	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Mouse	Liver	rep_16	9.9e-21
Bola2	GOBP_Protein_Maturation	Mouse	Liver	rep_16	4.5e-09
Bola2	GOBP_Response_To_Cytokine	Mouse	Liver	rep_16	1.4e-13
Bola2	GOBP_Transition_Metal_Ion_Homeostasis	Mouse	Liver	rep_16	5.7e-28
Bola2	GOBP_Cellular_Iron_Ion_Homeostasis	Mouse	Intestine	rep_2	1.2e-20
Bola2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Intestine	rep_2	7.1e-07
Bola2	GOBP_2fe_2s_Cluster_Assembly	Mouse	Lymph	MS-1	1.0e-08
Bola2	GOBP_Cellular_Homeostasis	Mouse	Lymph	MS-1	8.2e-11
Bola2	GOBP_Cellular_Ion_Homeostasis	Mouse	Lymph	MS-1	4.0e-14
Bola2	GOBP_Cellular_Iron_Ion_Homeostasis	Mouse	Lymph	MS-1	4.2e-14
Bola2	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Mouse	Lymph	MS-1	2.9e-14
Bola2	GOBP_Chemical_Homeostasis	Mouse	Lymph	MS-1	8.2e-11
Bola2	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	6.7e-17
Bola2	GOBP_Homeostatic_Process	Mouse	Lymph	MS-1	2.3e-12
Bola2	GOBP_Ion_Homeostasis	Mouse	Lymph	MS-1	7.3e-10
Bola2	GOBP_Iron_Ion_Homeostasis	Mouse	Lymph	MS-1	4.1e-12
Bola2	GOBP_Iron_Sulfur_Cluster_Assembly	Mouse	Lymph	MS-1	8.0e-11
Bola2	GOBP_Metal_Ion_Homeostasis	Mouse	Lymph	MS-1	4.9e-13
Bola2	GOBP_Response_To_Cytokine	Mouse	Lymph	MS-1	5.7e-15
Bola2	GOBP_Response_To_Interleukin_12	Mouse	Lymph	MS-1	8.3e-11
Bola2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Lymph	MS-1	7.8e-10
Bola2	GOBP_Transition_Metal_Ion_Homeostasis	Mouse	Lymph	MS-1	6.0e-11
Bola2	GOBP_Protein_Maturation_By_Iron_Sulfur_Cluster_Transfer	Mouse	Lymph	MS-2	5.3e-07
Bola2	GOBP_Response_To_Cytokine	Mouse	Lung	rep_1	1.2e-17
Bola2	GOBP_Iron_Sulfur_Cluster_Assembly	Mouse	Brain	rep_7	3.2e-09
Bola2	GOBP_2fe_2s_Cluster_Assembly	Mouse	Brain	HP_ad_rep3	3.5e-15
Bola2	GOBP_Iron_Sulfur_Cluster_Assembly	Mouse	Brain	HP_ad_rep3	2.8e-11
Bola2	GOBP_Protein_Maturation_By_Iron_Sulfur_Cluster_Transfer	Mouse	Brain	HP_ad_rep3	3.1e-10
Bola2	GOBP_Response_To_Cytokine	Mouse	Brain	HP_ad_rep7	2.1e-08
Bola2	GOBP_Response_To_Interleukin_12	Mouse	Brain	HP_ad_rep7	1.2e-14
Bola2	GOBP_Cellular_Homeostasis	Mouse	Brain	HP_polb_rep9	1.2e-09
Bola2	GOBP_Cellular_Ion_Homeostasis	Mouse	Brain	HP_polb_rep9	1.5e-09
Bola2	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Mouse	Brain	HP_polb_rep9	8.3e-08
Bola2	GOBP_Chemical_Homeostasis	Mouse	Brain	HP_polb_rep9	9.6e-10
Bola2	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	5.5e-07
Bola2	GOBP_Homeostatic_Process	Mouse	Brain	HP_polb_rep9	6.4e-11
Bola2	GOBP_Ion_Homeostasis	Mouse	Brain	HP_polb_rep9	1.5e-08
Bola2	GOBP_Metal_Ion_Homeostasis	Mouse	Brain	HP_polb_rep9	1.2e-07
Bola2	GOBP_Protein_Maturation	Mouse	Brain	HP_polb_rep9	9.1e-14
Bola2	GOBP_Sulfur_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-08

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Bola2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Bola2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Bola2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Bola2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Bola2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source