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Spatial pattern gene: Necap2 (spascer ID:66147) |
Gene summary for Necap2 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Necap2 | Gene ID | 66147 |
| Gene name | NECAP endocytosis associated 2 |
| Synonyms | 1110005F07Rik|AA409105|C78898|NECAP-2 |
| Cytomap | 4|4 D3 |
| Type of gene | protein-coding |
| Description | adaptin ear-binding coat-associated protein 2NECAP endocytosis-associated protein 2clathrin-coated vesicle coat proteinlikely ortholog of H. sapiens adaptin-ear-binding coat-associated protein 2 (NECAP2) |
| Modification date | 20220424 |
| UniProtAcc | Q9D1J1 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Necap2 | GO:0016192 | vesicle-mediated transport | 21873635 | Process |
| Necap2 | GO:0030125 | clathrin vesicle coat | 21873635 | Component |
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Spatial pattern events for Necap2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Necap2 | Mouse | Brain | S4 | 34413515 | 2.43e-15 |
| Necap2 | Mouse | Brain | S6 | 34413515 | 6.59e-10 |
| Necap2 | Mouse | Brain | rep_1 | 35141374 | 2.67e-06 |
| Necap2 | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Necap2 | Mouse | Brain | rep_3 | 35141374 | 3.61e-10 |
| Necap2 | Mouse | Brain | rep_4 | 35141374 | 1.40e-12 |
| Necap2 | Mouse | Brain | rep_5 | 35141374 | 4.19e-13 |
| Necap2 | Mouse | Kidney | CLP | 34003797 | 3.77e-15 |
| Necap2 | Mouse | Kidney | rep_1 | 34853151 | 1.05e-10 |
| Necap2 | Mouse | Brain | rep_1 | 33469025 | 5.21e-08 |
| Necap2 | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Necap2 | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Necap2 | Mouse | Brain | rep_3 | 35027729 | 2.38e-15 |
| Necap2 | Mouse | Brain | rep_5 | 35027729 | 2.62e-15 |
| Necap2 | Mouse | Intestine | rep_2 | 35149721 | 5.07e-06 |
| Necap2 | Mouse | Lymph | A1 | 0 | 6.91e-10 |
| Necap2 | Mouse | Brain | rep_1 | 35210624 | 6.90e-06 |
| Necap2 | Mouse | Brain | rep_2 | 35210624 | 2.32e-10 |
| Necap2 | Mouse | Brain | rep_3 | 35210624 | 8.02e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_rep_1_H&E  |  |
Brain_rep_1_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_5_H&E  |  |
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Spatial pattern pathway has Necap2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Necap2 | GOBP_Endocytosis | Mouse | Spinal cord | CN94_E1 | 8.2e-06 |
| Necap2 | GOBP_Establishment_Of_Protein_Localization | Mouse | Spinal cord | L7CN45_C1 | 4.4e-06 |
| Necap2 | GOBP_Establishment_Of_Protein_Localization | Mouse | Brain | rep_1 | 6.6e-07 |
| Necap2 | GOBP_Endocytosis | Mouse | Brain | rep_3 | 2.6e-20 |
| Necap2 | GOBP_Endocytosis | Mouse | Kidney | Nep | 8.3e-23 |
| Necap2 | GOBP_Endocytosis | Mouse | Kidney | rep_2 | 1.4e-132 |
| Necap2 | GOBP_Establishment_Of_Protein_Localization | Mouse | Kidney | rep_2 | 9.8e-86 |
| Necap2 | GOBP_Endocytosis | Mouse | Lymph | MS-1 | 1.8e-21 |
| Necap2 | GOBP_Establishment_Of_Protein_Localization | Mouse | Lymph | MS-1 | 2.5e-11 |
| Necap2 | GOBP_Establishment_Of_Protein_Localization | Mouse | Brain | HP_ad_rep7 | 8.7e-10 |
| Necap2 | GOBP_Endocytosis | Mouse | Brain | HP_polb_rep9 | 3.2e-09 |
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Necap2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Necap2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Necap2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Necap2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Necap2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
