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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Cox7b (spascer ID:66142)

Gene summary for Cox7b

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Cox7b
	Gene ID	66142
	Gene name	cytochrome c oxidase subunit 7B
	Synonyms	1110004F07Rik\|C80563
	Cytomap	X\|X D
	Type of gene	protein-coding
	Description	cytochrome c oxidase subunit 7B, mitochondrialcytochrome c oxidase polypeptide VIIbcytochrome c oxidase subunit VIIb
	Modification date	20220424
	UniProtAcc	P56393

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Cox7b	GO:0005739	mitochondrion	21873635	Component
Cox7b	GO:0045277	respiratory chain complex IV	21873635	Component

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Spatial pattern events for Cox7b

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Cox7b	Mouse	Brain	S1	34413515	2.07e-15
Cox7b	Mouse	Brain	S2	34413515	1.56e-15
Cox7b	Mouse	Brain	S3	34413515	1.64e-15
Cox7b	Mouse	Brain	S4	34413515	1.37e-15
Cox7b	Mouse	Brain	S6	34413515	1.46e-15
Cox7b	Mouse	Brain	S7	34413515	1.55e-15
Cox7b	Mouse	Brain	08A	32637622	2.31e-06
Cox7b	Mouse	Brain	18A	32637622	1.80e-07
Cox7b	Mouse	Brain	18B	32637622	4.45e-06
Cox7b	Mouse	Brain	21A	32637622	3.33e-06
Cox7b	Mouse	Brain	22A	32637622	8.87e-15
Cox7b	Mouse	Brain	22B	32637622	1.63e-06
Cox7b	Mouse	Brain	23A	32637622	2.52e-07
Cox7b	Mouse	Brain	25A	32637622	3.33e-10
Cox7b	Mouse	Brain	27A	32637622	3.25e-08
Cox7b	Mouse	Brain	27B	32637622	4.63e-12
Cox7b	Mouse	Brain	28A	32637622	1.06e-14
Cox7b	Mouse	Brain	28B	32637622	1.24e-14
Cox7b	Mouse	Brain	29A	32637622	1.82e-14
Cox7b	Mouse	Brain	29B	32637622	1.08e-14
Cox7b	Mouse	Brain	30A	32637622	6.45e-09
Cox7b	Mouse	Brain	31A	32637622	2.62e-06
Cox7b	Mouse	Brain	36B	32637622	1.18e-06
Cox7b	Mouse	Brain	37B	32637622	4.72e-06
Cox7b	Mouse	Brain	38B	32637622	1.01e-06
Cox7b	Mouse	Brain	rep_1	35141374	3.58e-15
Cox7b	Mouse	Brain	rep_2	35141374	1.69e-15
Cox7b	Mouse	Brain	rep_3	35141374	1.64e-15
Cox7b	Mouse	Brain	rep_4	35141374	1.57e-15
Cox7b	Mouse	Brain	rep_5	35141374	1.47e-15
Cox7b	Mouse	Brain	rep_6	35141374	1.73e-15
Cox7b	Mouse	Embryo	rep_12	33188776	3.81e-09
Cox7b	Mouse	Embryo	rep_13	33188776	4.49e-15
Cox7b	Mouse	Embryo	rep_15	33188776	6.73e-11
Cox7b	Mouse	Kidney	CLP	34003797	2.19e-15
Cox7b	Mouse	Kidney	IRI	34003797	2.29e-15
Cox7b	Mouse	Kidney	Sham	34003797	2.58e-15
Cox7b	Mouse	Kidney	rep_1	34853151	2.42e-15
Cox7b	Mouse	Kidney	rep_2	34853151	3.38e-15
Cox7b	Mouse	Kidney	rep_3	34853151	2.94e-15
Cox7b	Mouse	Kidney	rep_4	34853151	6.41e-06
Cox7b	Mouse	Kidney	rep_5	34853151	5.45e-15
Cox7b	Mouse	Brain	rep_1	33469025	1.30e-15
Cox7b	Mouse	Liver	rep_17	35021063	4.77e-14
Cox7b	Mouse	Liver	rep_21	35021063	9.92e-06
Cox7b	Mouse	Liver	rep_22	35021063	2.31e-06
Cox7b	Mouse	Liver	rep_23	35021063	4.15e-11
Cox7b	Mouse	Brain	rep_1	35027729	1.66e-15
Cox7b	Mouse	Brain	rep_2	35027729	1.57e-15
Cox7b	Mouse	Brain	rep_3	35027729	1.32e-15
Cox7b	Mouse	Brain	rep_4	35027729	1.76e-15
Cox7b	Mouse	Brain	rep_5	35027729	1.46e-15
Cox7b	Mouse	Intestine	rep_1	35149721	1.03e-14
Cox7b	Mouse	Intestine	rep_2	35149721	3.44e-15
Cox7b	Mouse	Intestine	rep_3	35149721	3.25e-15
Cox7b	Mouse	Intestine	rep_4	35149721	3.90e-15
Cox7b	Mouse	Brain	B04_E1	32702314	8.88e-12
Cox7b	Mouse	Brain	B05_D2	32702314	2.54e-14
Cox7b	Mouse	Brain	B05_E2	32702314	3.51e-08
Cox7b	Mouse	Brain	N03_D2	32702314	7.88e-12
Cox7b	Mouse	Brain	N07_C1	32702314	7.03e-13
Cox7b	Mouse	Lymph	A1	0	5.84e-15
Cox7b	Mouse	Lymph	B1	0	3.66e-15
Cox7b	Mouse	Lung	rep_1	35290801	4.52e-15
Cox7b	Mouse	Lung	rep_2	35290801	8.75e-15
Cox7b	Mouse	Lung	rep_3	35290801	5.26e-15
Cox7b	Mouse	Lung	rep_4	35290801	3.04e-15
Cox7b	Mouse	Brain	rep_1	35210624	1.74e-15
Cox7b	Mouse	Brain	rep_2	35210624	1.74e-15
Cox7b	Mouse	Brain	rep_3	35210624	1.82e-15
Cox7b	Mouse	Brain	rep_4	35210624	6.63e-14
Cox7b	Mouse	Brain	rep_5	35210624	2.07e-15
Cox7b	Mouse	Brain	rep_6	35210624	2.45e-13
Cox7b	Mouse	Brain	rep_7	35210624	1.87e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_17_H&E
Liver_rep_21_H&E
Liver_rep_22_H&E
Liver_rep_23_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B04_E1_H&E
Brain_B05_D2_H&E
Brain_B05_E2_H&E
Brain_N03_D2_H&E
Brain_N07_C1_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Cox7b envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Cox7b	GOBP_Cation_Transport	Mouse	Spinal cord	CN94_E1	5.8e-06
Cox7b	GOBP_Cation_Transmembrane_Transport	Mouse	Spinal cord	L7CN45_C1	1.3e-08
Cox7b	GOBP_Cellular_Respiration	Mouse	Spinal cord	L7CN45_C1	7.0e-07
Cox7b	GOBP_Central_Nervous_System_Development	Mouse	Spinal cord	L7CN45_C1	5.5e-10
Cox7b	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Spinal cord	L7CN45_C1	6.8e-07
Cox7b	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Spinal cord	L7CN45_C1	2.2e-08
Cox7b	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Spinal cord	L7CN45_C1	6.6e-07
Cox7b	GOBP_Oxidative_Phosphorylation	Mouse	Spinal cord	L7CN45_C1	5.1e-07
Cox7b	GOBP_Proton_Transmembrane_Transport	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Cox7b	GOBP_Transmembrane_Transport	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Cox7b	GOBP_Mitochondrial_Electron_Transport_Cytochrome_C_To_Oxygen	Mouse	Spinal cord	L7CN47_C1	7.0e-06
Cox7b	GOBP_Atp_Metabolic_Process	Mouse	Spinal cord	L7CN47_D1	3.0e-06
Cox7b	GOBP_Aerobic_Respiration	Mouse	Brain	rep_71	1.9e-06
Cox7b	GOBP_Atp_Metabolic_Process	Mouse	Brain	rep_71	2.7e-06
Cox7b	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Mouse	Brain	rep_71	1.2e-05
Cox7b	GOBP_Cellular_Respiration	Mouse	Brain	rep_71	1.7e-06
Cox7b	GOBP_Electron_Transport_Chain	Mouse	Brain	rep_71	2.4e-06
Cox7b	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Brain	rep_71	3.4e-07
Cox7b	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	rep_71	2.1e-06
Cox7b	GOBP_Oxidative_Phosphorylation	Mouse	Brain	rep_71	5.5e-06
Cox7b	GOBP_Proton_Transmembrane_Transport	Mouse	Brain	rep_71	1.6e-05
Cox7b	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Brain	rep_71	1.2e-05
Cox7b	GOBP_Aerobic_Respiration	Mouse	Brain	rep_1	5.5e-37
Cox7b	GOBP_Atp_Metabolic_Process	Mouse	Brain	rep_1	2.0e-14
Cox7b	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Mouse	Brain	rep_1	7.9e-39
Cox7b	GOBP_Cation_Transmembrane_Transport	Mouse	Brain	rep_1	4.4e-30
Cox7b	GOBP_Cation_Transport	Mouse	Brain	rep_1	1.5e-22
Cox7b	GOBP_Cellular_Respiration	Mouse	Brain	rep_1	9.5e-36
Cox7b	GOBP_Central_Nervous_System_Development	Mouse	Brain	rep_1	8.6e-30
Cox7b	GOBP_Electron_Transport_Chain	Mouse	Brain	rep_1	1.3e-47
Cox7b	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Brain	rep_1	1.1e-29
Cox7b	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	rep_1	5.4e-15
Cox7b	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Brain	rep_1	8.6e-24
Cox7b	GOBP_Mitochondrial_Electron_Transport_Cytochrome_C_To_Oxygen	Mouse	Brain	rep_1	5.4e-41
Cox7b	GOBP_Oxidative_Phosphorylation	Mouse	Brain	rep_1	7.5e-43
Cox7b	GOBP_Proton_Transmembrane_Transport	Mouse	Brain	rep_1	2.0e-34
Cox7b	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Brain	rep_1	4.5e-44
Cox7b	GOBP_Transmembrane_Transport	Mouse	Brain	rep_1	3.1e-23
Cox7b	GOBP_Cellular_Respiration	Mouse	Embryo	rep_6	3.9e-08
Cox7b	GOBP_Aerobic_Respiration	Mouse	Embryo	rep_14	4.2e-31
Cox7b	GOBP_Atp_Metabolic_Process	Mouse	Embryo	rep_14	3.7e-37
Cox7b	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Mouse	Embryo	rep_14	3.4e-58
Cox7b	GOBP_Electron_Transport_Chain	Mouse	Embryo	rep_14	5.7e-46
Cox7b	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Embryo	rep_14	2.3e-31
Cox7b	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Embryo	rep_14	2.9e-37
Cox7b	GOBP_Mitochondrial_Electron_Transport_Cytochrome_C_To_Oxygen	Mouse	Embryo	rep_14	2.1e-62
Cox7b	GOBP_Oxidative_Phosphorylation	Mouse	Embryo	rep_14	7.0e-41
Cox7b	GOBP_Proton_Transmembrane_Transport	Mouse	Embryo	rep_14	6.6e-33
Cox7b	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Embryo	rep_14	8.9e-41
Cox7b	GOBP_Central_Nervous_System_Development	Mouse	Embryo	rep_1	3.0e-261
Cox7b	GOBP_Electron_Transport_Chain	Mouse	Embryo	rep_3	3.7e-124
Cox7b	GOBP_Central_Nervous_System_Development	Mouse	Kidney	Nep	4.2e-26
Cox7b	GOBP_Transmembrane_Transport	Mouse	Kidney	Nep	4.2e-26
Cox7b	GOBP_Cation_Transmembrane_Transport	Mouse	Kidney	rep_2	7.3e-17
Cox7b	GOBP_Cation_Transport	Mouse	Kidney	rep_2	5.9e-23
Cox7b	GOBP_Central_Nervous_System_Development	Mouse	Kidney	rep_2	1.3e-23
Cox7b	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Kidney	rep_2	3.3e-14
Cox7b	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Kidney	rep_2	2.4e-15
Cox7b	GOBP_Proton_Transmembrane_Transport	Mouse	Kidney	rep_2	1.5e-08
Cox7b	GOBP_Transmembrane_Transport	Mouse	Kidney	rep_2	2.7e-23
Cox7b	GOBP_Mitochondrial_Electron_Transport_Cytochrome_C_To_Oxygen	Mouse	Liver	CN16-D1	1.1e-11
Cox7b	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Mouse	Liver	CN65-C1	1.6e-09
Cox7b	GOBP_Cation_Transmembrane_Transport	Mouse	Liver	rep_15	8.9e-14
Cox7b	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Liver	rep_15	2.4e-07
Cox7b	GOBP_Mitochondrial_Electron_Transport_Cytochrome_C_To_Oxygen	Mouse	Liver	rep_15	2.0e-25
Cox7b	GOBP_Proton_Transmembrane_Transport	Mouse	Liver	rep_15	8.1e-10
Cox7b	GOBP_Aerobic_Respiration	Mouse	Liver	rep_16	2.7e-35
Cox7b	GOBP_Atp_Metabolic_Process	Mouse	Liver	rep_16	1.2e-30
Cox7b	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Mouse	Liver	rep_16	4.4e-24
Cox7b	GOBP_Cation_Transport	Mouse	Liver	rep_16	1.2e-18
Cox7b	GOBP_Cellular_Respiration	Mouse	Liver	rep_16	8.0e-25
Cox7b	GOBP_Central_Nervous_System_Development	Mouse	Liver	rep_16	8.2e-15
Cox7b	GOBP_Electron_Transport_Chain	Mouse	Liver	rep_16	1.7e-16
Cox7b	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Liver	rep_16	2.0e-28
Cox7b	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Liver	rep_16	7.4e-11
Cox7b	GOBP_Oxidative_Phosphorylation	Mouse	Liver	rep_16	1.4e-27
Cox7b	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Liver	rep_16	2.4e-29
Cox7b	GOBP_Transmembrane_Transport	Mouse	Liver	rep_16	1.4e-13
Cox7b	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Mouse	Intestine	rep_2	3.8e-16
Cox7b	GOBP_Electron_Transport_Chain	Mouse	Intestine	rep_2	8.8e-09
Cox7b	GOBP_Mitochondrial_Electron_Transport_Cytochrome_C_To_Oxygen	Mouse	Intestine	rep_2	1.7e-60
Cox7b	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Intestine	rep_2	2.9e-16
Cox7b	GOBP_Central_Nervous_System_Development	Mouse	Lymph	MS-1	3.8e-07
Cox7b	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Mouse	Lymph	MS-2	8.2e-07
Cox7b	GOBP_Mitochondrial_Electron_Transport_Cytochrome_C_To_Oxygen	Mouse	Lymph	MS-2	2.3e-09
Cox7b	GOBP_Cation_Transport	Mouse	Brain	HP_ad_rep7	7.5e-07
Cox7b	GOBP_Central_Nervous_System_Development	Mouse	Brain	HP_ad_rep7	2.3e-07
Cox7b	GOBP_Transmembrane_Transport	Mouse	Brain	HP_ad_rep7	3.4e-07
Cox7b	GOBP_Aerobic_Respiration	Mouse	Brain	HP_polb_rep9	1.4e-09
Cox7b	GOBP_Atp_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.0e-11
Cox7b	GOBP_Atp_Synthesis_Coupled_Electron_Transport	Mouse	Brain	HP_polb_rep9	4.5e-08
Cox7b	GOBP_Cation_Transmembrane_Transport	Mouse	Brain	HP_polb_rep9	1.4e-07
Cox7b	GOBP_Cellular_Respiration	Mouse	Brain	HP_polb_rep9	2.1e-07
Cox7b	GOBP_Electron_Transport_Chain	Mouse	Brain	HP_polb_rep9	5.9e-10
Cox7b	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Brain	HP_polb_rep9	3.0e-10
Cox7b	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	HP_polb_rep9	5.4e-11
Cox7b	GOBP_Inorganic_Ion_Transmembrane_Transport	Mouse	Brain	HP_polb_rep9	1.1e-07
Cox7b	GOBP_Mitochondrial_Electron_Transport_Cytochrome_C_To_Oxygen	Mouse	Brain	HP_polb_rep9	1.3e-07
Cox7b	GOBP_Oxidative_Phosphorylation	Mouse	Brain	HP_polb_rep9	9.8e-11
Cox7b	GOBP_Proton_Transmembrane_Transport	Mouse	Brain	HP_polb_rep9	1.5e-08
Cox7b	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Brain	HP_polb_rep9	1.8e-08

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Cox7b function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Cox7b function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Cox7b envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Cox7b

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Cox7b

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Cox7b	C3550921	LINEAR SKIN DEFECTS WITH MULTIPLE CONGENITAL ANOMALIES 2	3	CTD_human;GENOMICS_ENGLAND
Cox7b	C0796070	MICROPHTHALMIA, SYNDROMIC 7	1	CTD_human;ORPHANET