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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Ska2 (spascer ID:66140)

Gene summary for Ska2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Ska2
	Gene ID	66140
	Gene name	spindle and kinetochore associated complex subunit 2
	Synonyms	1110001A07Rik\|C78640\|Fam33a
	Cytomap	11\|11 C
	Type of gene	protein-coding
	Description	spindle and kinetochore-associated protein 2family with sequence similarity 33, member A
	Modification date	20220424
	UniProtAcc	Q9CR46

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Ska2	GO:0000278	mitotic cell cycle	21873635	Process
Ska2	GO:0000940	outer kinetochore	21873635	Component
Ska2	GO:0005876	spindle microtubule	21873635	Component
Ska2	GO:0007059	chromosome segregation	21873635	Process
Ska2	GO:0008017	microtubule binding	21873635	Function

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Spatial pattern events for Ska2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Ska2	Mouse	Kidney	CLP	34003797	4.96e-12
Ska2	Mouse	Brain	rep_1	33469025	5.56e-12
Ska2	Mouse	Testicle	rep_4	34731600	1.99e-11
Ska2	Mouse	Lymph	A1	0	1.70e-07
Ska2	Mouse	Lymph	B1	0	6.08e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Brain_rep_1_H&E

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Spatial pattern pathway has Ska2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Ska2	GOBP_Cell_Cycle	Mouse	Spinal cord	CN94_E1	1.1e-06
Ska2	GOBP_Microtubule_Based_Process	Mouse	Spinal cord	CN94_E1	2.4e-06
Ska2	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Ska2	GOBP_Cell_Division	Mouse	Spinal cord	L7CN45_C1	2.6e-06
Ska2	GOBP_Chromosome_Segregation	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Ska2	GOBP_Mitotic_Cell_Cycle	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Ska2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Spinal cord	L7CN45_C1	1.5e-07
Ska2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Spinal cord	L7CN45_C1	8.1e-06
Ska2	GOBP_Cell_Cycle	Mouse	Brain	rep_27	8.4e-07
Ska2	GOBP_Cell_Division	Mouse	Brain	rep_27	3.6e-05
Ska2	GOBP_Mitotic_Cell_Cycle	Mouse	Brain	rep_27	1.1e-05
Ska2	GOBP_Cell_Cycle	Mouse	Brain	rep_1	7.0e-10
Ska2	GOBP_Cell_Division	Mouse	Brain	rep_1	9.7e-23
Ska2	GOBP_Chromosome_Segregation	Mouse	Brain	rep_1	6.3e-08
Ska2	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Ska2	GOBP_Microtubule_Based_Process	Mouse	Brain	rep_1	1.6e-07
Ska2	GOBP_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	rep_1	6.8e-20
Ska2	GOBP_Mitotic_Cell_Cycle	Mouse	Brain	rep_1	1.5e-25
Ska2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-40
Ska2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Brain	rep_1	2.0e-17
Ska2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Brain	rep_1	4.8e-24
Ska2	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	rep_1	7.9e-26
Ska2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	rep_1	7.9e-20
Ska2	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Brain	rep_3	8.5e-140
Ska2	GOBP_Cell_Division	Mouse	Embryo	rep_1	0.0e+00
Ska2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Embryo	rep_1	2.6e-63
Ska2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Embryo	rep_3	1.3e-27
Ska2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Embryo	rep_5	4.2e-125
Ska2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Embryo	rep_5	4.2e-125
Ska2	GOBP_Cell_Cycle	Mouse	Kidney	rep_2	1.0e-24
Ska2	GOBP_Cell_Division	Mouse	Kidney	rep_2	5.3e-77
Ska2	GOBP_Chromosome_Segregation	Mouse	Kidney	rep_2	8.3e-67
Ska2	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Ska2	GOBP_Mitotic_Cell_Cycle	Mouse	Kidney	rep_2	1.1e-15
Ska2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.8e-22
Ska2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Kidney	rep_2	6.7e-77
Ska2	GOBP_Microtubule_Based_Process	Mouse	Liver	CN16-D2	1.8e-11
Ska2	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Liver	CN16-D2	2.8e-10
Ska2	GOBP_Microtubule_Polymerization_Or_Depolymerization	Mouse	Liver	CN65-C1	6.4e-09
Ska2	GOBP_Microtubule_Polymerization_Or_Depolymerization	Mouse	Liver	rep_16	7.4e-11
Ska2	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Liver	rep_16	7.8e-13
Ska2	GOBP_Cell_Cycle	Mouse	Lymph	MS-1	1.3e-07
Ska2	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Ska2	GOBP_Microtubule_Based_Process	Mouse	Lymph	MS-1	1.5e-08
Ska2	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Lymph	MS-1	7.6e-07
Ska2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Lymph	MS-1	8.4e-09
Ska2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Lymph	MS-1	1.4e-10
Ska2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Brain	rep_4	2.3e-16
Ska2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Brain	rep_4	2.6e-09
Ska2	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	rep_4	3.0e-27
Ska2	GOBP_Cell_Cycle	Mouse	Brain	HP_ad_rep7	6.6e-08
Ska2	GOBP_Cell_Division	Mouse	Brain	HP_ad_rep7	2.6e-09
Ska2	GOBP_Chromosome_Segregation	Mouse	Brain	HP_ad_rep7	4.9e-08
Ska2	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Ska2	GOBP_Microtubule_Based_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Ska2	GOBP_Microtubule_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	3.8e-13
Ska2	GOBP_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	HP_ad_rep7	7.6e-16
Ska2	GOBP_Regulation_Of_Microtubule_Based_Process	Mouse	Brain	HP_ad_rep7	3.2e-13
Ska2	GOBP_Regulation_Of_Microtubule_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	8.7e-15
Ska2	GOBP_Regulation_Of_Microtubule_Polymerization_Or_Depolymerization	Mouse	Brain	HP_ad_rep7	5.7e-18
Ska2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	HP_ad_rep7	8.1e-07
Ska2	GOBP_Mitotic_Cell_Cycle	Mouse	Brain	HP_polb_rep9	1.6e-10
Ska2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	HP_polb_rep9	1.1e-07

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Ska2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Ska2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Ska2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Ska2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Ska2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source