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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Ppih (spascer ID:66101)

Gene summary for Ppih

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Ppih
	Gene ID	66101
	Gene name	peptidyl prolyl isomerase H
	Synonyms	1100001J08Rik\|2010111B15Rik\|4833408F11Rik\|AI464484\|CYP-20\|CYPH\|D4Wsu43e
	Cytomap	4 D2.1\|4 55.34 cM
	Type of gene	protein-coding
	Description	peptidyl-prolyl cis-trans isomerase HPPIase Hcyclophilin Hrotamase H
	Modification date	20220424
	UniProtAcc	Q9D868

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Ppih	GO:0000413	protein peptidyl-prolyl isomerization	21873635	Process
Ppih	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	21873635	Function
Ppih	GO:0005737	cytoplasm	21873635	Component
Ppih	GO:0006457	protein folding	21873635	Process
Ppih	GO:0016018	cyclosporin A binding	21873635	Function
Ppih	GO:0043231	intracellular membrane-bounded organelle	21873635	Component

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Spatial pattern events for Ppih

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Ppih	Mouse	Kidney	rep_5	34853151	8.82e-13
Ppih	Mouse	Brain	rep_1	33469025	1.30e-15
Ppih	Mouse	Testicle	rep_4	34731600	1.37e-15
Ppih	Mouse	Lymph	A1	0	3.29e-15
Ppih	Mouse	Lymph	B1	0	3.66e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_5_H&E
Brain_rep_1_H&E

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Spatial pattern pathway has Ppih envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Ppih	GOBP_Mrna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.9e-06
Ppih	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Spinal cord	CN94_E1	5.5e-06
Ppih	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Spinal cord	L7bCN01_D2	4.3e-06
Ppih	GOBP_Mrna_Processing	Mouse	Spinal cord	L7bCN02_E1	5.5e-06
Ppih	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Ppih	GOBP_Peptidyl_Proline_Modification	Mouse	Spinal cord	L7CN45_C1	1.3e-07
Ppih	GOBP_Positive_Regulation_Of_Viral_Process	Mouse	Spinal cord	L7CN45_C1	3.8e-07
Ppih	GOBP_Protein_Peptidyl_Prolyl_Isomerization	Mouse	Spinal cord	L7CN45_C1	1.3e-07
Ppih	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Ppih	GOBP_Rna_Splicing	Mouse	Spinal cord	L7CN45_C1	3.7e-08
Ppih	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Spinal cord	L7CN45_C1	1.8e-09
Ppih	GOBP_Viral_Genome_Replication	Mouse	Spinal cord	L7CN45_C1	5.2e-06
Ppih	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Spinal cord	L7CN97_E2	6.8e-06
Ppih	GOBP_Positive_Regulation_Of_Viral_Genome_Replication	Mouse	Spinal cord	L7CN97_E2	1.6e-06
Ppih	GOBP_Viral_Life_Cycle	Mouse	Spinal cord	L7CN97_E2	7.3e-06
Ppih	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Brain	rep_1	9.0e-07
Ppih	GOBP_Peptidyl_Proline_Modification	Mouse	Brain	rep_1	1.4e-09
Ppih	GOBP_Protein_Peptidyl_Prolyl_Isomerization	Mouse	Brain	rep_1	6.0e-11
Ppih	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	rep_3	1.9e-146
Ppih	GOBP_Mrna_Metabolic_Process	Mouse	Brain	rep_3	3.9e-221
Ppih	GOBP_Mrna_Processing	Mouse	Brain	rep_3	4.7e-219
Ppih	GOBP_Positive_Regulation_Of_Viral_Genome_Replication	Mouse	Brain	rep_3	3.4e-164
Ppih	GOBP_Positive_Regulation_Of_Viral_Process	Mouse	Brain	rep_3	1.5e-168
Ppih	GOBP_Protein_Folding	Mouse	Brain	rep_3	5.7e-177
Ppih	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Brain	rep_3	1.1e-144
Ppih	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Ppih	GOBP_Rna_Splicing	Mouse	Brain	rep_3	2.2e-224
Ppih	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	rep_3	1.8e-234
Ppih	GOBP_Viral_Genome_Replication	Mouse	Brain	rep_3	9.0e-141
Ppih	GOBP_Viral_Life_Cycle	Mouse	Brain	rep_3	8.3e-131
Ppih	GOBP_Positive_Regulation_Of_Viral_Genome_Replication	Mouse	Embryo	rep_6	1.6e-12
Ppih	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Embryo	rep_6	2.4e-10
Ppih	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Embryo	rep_6	1.2e-12
Ppih	GOBP_Peptidyl_Proline_Modification	Mouse	Embryo	rep_14	4.8e-45
Ppih	GOBP_Protein_Folding	Mouse	Embryo	rep_14	3.2e-12
Ppih	GOBP_Protein_Peptidyl_Prolyl_Isomerization	Mouse	Embryo	rep_14	3.6e-34
Ppih	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Ppih	GOBP_Viral_Genome_Replication	Mouse	Embryo	rep_14	3.7e-09
Ppih	GOBP_Mrna_Metabolic_Process	Mouse	Embryo	rep_1	5.8e-21
Ppih	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Embryo	rep_1	0.0e+00
Ppih	GOBP_Viral_Genome_Replication	Mouse	Embryo	rep_1	0.0e+00
Ppih	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Embryo	rep_2	7.4e-121
Ppih	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Ppih	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Embryo	rep_3	0.0e+00
Ppih	GOBP_Viral_Life_Cycle	Mouse	Embryo	rep_4	5.2e-15
Ppih	GOBP_Mrna_Metabolic_Process	Mouse	Kidney	rep_2	3.1e-08
Ppih	GOBP_Mrna_Processing	Mouse	Kidney	rep_2	5.0e-53
Ppih	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Kidney	rep_2	6.9e-23
Ppih	GOBP_Peptidyl_Proline_Modification	Mouse	Kidney	rep_2	1.2e-44
Ppih	GOBP_Positive_Regulation_Of_Viral_Genome_Replication	Mouse	Kidney	rep_2	2.3e-66
Ppih	GOBP_Positive_Regulation_Of_Viral_Process	Mouse	Kidney	rep_2	7.0e-40
Ppih	GOBP_Protein_Peptidyl_Prolyl_Isomerization	Mouse	Kidney	rep_2	2.7e-54
Ppih	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Kidney	rep_2	2.5e-65
Ppih	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Kidney	rep_2	2.2e-44
Ppih	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Ppih	GOBP_Rna_Splicing	Mouse	Kidney	rep_2	1.1e-33
Ppih	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Kidney	rep_2	8.8e-36
Ppih	GOBP_Viral_Genome_Replication	Mouse	Kidney	rep_2	4.6e-17
Ppih	GOBP_Peptidyl_Proline_Modification	Mouse	Liver	CN16-D1	6.1e-09
Ppih	GOBP_Positive_Regulation_Of_Viral_Genome_Replication	Mouse	Liver	CN16-D1	5.4e-07
Ppih	GOBP_Mrna_Metabolic_Process	Mouse	Liver	CN16-D2	5.2e-07
Ppih	GOBP_Mrna_Processing	Mouse	Liver	CN16-D2	4.8e-09
Ppih	GOBP_Positive_Regulation_Of_Viral_Process	Mouse	Liver	CN16-D2	4.2e-07
Ppih	GOBP_Rna_Splicing	Mouse	Liver	CN16-D2	2.4e-07
Ppih	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Liver	CN16-D2	2.0e-09
Ppih	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Lymph	MS-1	4.6e-18
Ppih	GOBP_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	3.2e-11
Ppih	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Lymph	MS-1	1.2e-13
Ppih	GOBP_Peptidyl_Proline_Modification	Mouse	Lymph	MS-1	2.7e-10
Ppih	GOBP_Positive_Regulation_Of_Viral_Process	Mouse	Lymph	MS-1	6.7e-22
Ppih	GOBP_Protein_Folding	Mouse	Lymph	MS-1	1.6e-14
Ppih	GOBP_Protein_Peptidyl_Prolyl_Isomerization	Mouse	Lymph	MS-1	7.8e-09
Ppih	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Lymph	MS-1	3.1e-25
Ppih	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Ppih	GOBP_Viral_Genome_Replication	Mouse	Lymph	MS-1	6.0e-11
Ppih	GOBP_Viral_Life_Cycle	Mouse	Lymph	MS-1	5.7e-13
Ppih	GOBP_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-09
Ppih	GOBP_Mrna_Processing	Mouse	Brain	HP_ad_rep7	2.3e-09
Ppih	GOBP_Peptidyl_Amino_Acid_Modification	Mouse	Brain	HP_ad_rep7	3.2e-08
Ppih	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	HP_ad_rep7	6.6e-21
Ppih	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Ppih	GOBP_Rna_Splicing	Mouse	Brain	HP_ad_rep7	5.3e-10
Ppih	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	HP_ad_rep7	2.3e-11
Ppih	GOBP_Protein_Folding	Mouse	Brain	HP_adpolb_rep1	5.2e-07
Ppih	GOBP_Positive_Regulation_Of_Viral_Process	Mouse	Brain	HP_adpolb_rep3	6.6e-07
Ppih	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	HP_polb_rep9	1.1e-12
Ppih	GOBP_Peptidyl_Proline_Modification	Mouse	Brain	HP_polb_rep9	1.3e-15
Ppih	GOBP_Positive_Regulation_Of_Viral_Genome_Replication	Mouse	Brain	HP_polb_rep9	2.3e-07
Ppih	GOBP_Protein_Peptidyl_Prolyl_Isomerization	Mouse	Brain	HP_polb_rep9	9.4e-11
Ppih	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Brain	HP_polb_rep9	2.7e-08
Ppih	GOBP_Viral_Genome_Replication	Mouse	Brain	HP_polb_rep9	9.1e-08
Ppih	GOBP_Viral_Life_Cycle	Mouse	Brain	HP_polb_rep9	5.6e-08

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Ppih function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Ppih function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Ppih envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Ppih

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Ppih

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source