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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Ndufs5 (spascer ID:595136)

Gene summary for Ndufs5

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Ndufs5

Gene ID

595136

Gene nameNADH:ubiquinone oxidoreductase core subunit S5
SynonymsAI256693
Cytomap4|4 D2.2
Type of geneprotein-coding
DescriptionNADH dehydrogenase [ubiquinone] iron-sulfur protein 5CI-15 kDaNADH dehydrogenase (ubiquinone) Fe-S protein 5NADH-ubiquinone oxidoreductase 15 kDa subunitcomplex I-15 kDa
Modification date20220424
UniProtAcc

Q99LY9


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Ndufs5

GO:0005747

mitochondrial respiratory chain complex I

21873635

Component
Ndufs5

GO:0032981

mitochondrial respiratory chain complex I assembly

21873635

Process

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Spatial pattern events for Ndufs5

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Ndufs5MouseBrainS1 344135158.60e-08
Ndufs5MouseBrainS2 344135151.56e-15
Ndufs5MouseBrainS3 344135151.64e-15
Ndufs5MouseBrainS4 344135151.37e-15
Ndufs5MouseBrainS6 344135151.46e-15
Ndufs5MouseBrainS7 344135151.55e-15
Ndufs5MouseBrainrep_1 351413742.02e-15
Ndufs5MouseBrainrep_2 351413741.69e-15
Ndufs5MouseBrainrep_3 351413741.64e-15
Ndufs5MouseBrainrep_4 351413741.57e-15
Ndufs5MouseBrainrep_5 351413741.47e-15
Ndufs5MouseBrainrep_6 351413741.73e-15
Ndufs5MouseEmbryorep_5 331887763.55e-11
Ndufs5MouseEmbryorep_13 331887768.84e-06
Ndufs5MouseKidneyCLP 340037972.19e-15
Ndufs5MouseKidneyIRI 340037972.29e-15
Ndufs5MouseKidneySham 340037972.58e-15
Ndufs5MouseKidneyrep_1 348531512.42e-15
Ndufs5MouseKidneyrep_3 348531512.94e-15
Ndufs5MouseKidneyrep_5 348531513.18e-15
Ndufs5MouseBrainrep_1 334690251.30e-15
Ndufs5MouseLiverrep_23 350210632.21e-07
Ndufs5MouseIntestinerep_2 351497219.37e-10
Ndufs5MouseIntestinerep_3 351497211.66e-13
Ndufs5MouseIntestinerep_4 351497212.83e-14
Ndufs5MouseLymphA1 03.29e-15
Ndufs5MouseLymphB1 03.66e-15
Ndufs5MouseBrainrep_1 352106246.02e-15
Ndufs5MouseBrainrep_2 352106246.09e-08
Ndufs5MouseBrainrep_3 352106245.15e-07
Ndufs5MouseBrainrep_6 352106245.53e-13
Ndufs5MouseBrainrep_7 352106249.32e-07

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_6_H&E
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Kidney_CLP_H&E
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Kidney_IRI_H&E
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Kidney_Sham_H&E
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Kidney_rep_1_H&E
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Kidney_rep_3_H&E
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Kidney_rep_5_H&E
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Brain_rep_1_H&E
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Liver_rep_23_H&E
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Spatial pattern pathway has Ndufs5 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Ndufs5GOBP_Cellular_RespirationMouseSpinal cordL7CN45_C1 7.0e-07
Ndufs5GOBP_Energy_Derivation_By_Oxidation_Of_Organic_CompoundsMouseSpinal cordL7CN45_C1 6.8e-07
Ndufs5GOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseSpinal cordL7CN45_C1 2.2e-08
Ndufs5GOBP_Mitochondrion_OrganizationMouseSpinal cordL7CN45_C1 3.6e-07
Ndufs5GOBP_Oxidative_PhosphorylationMouseSpinal cordL7CN45_C1 5.1e-07
Ndufs5GOBP_Atp_Metabolic_ProcessMouseSpinal cordL7CN47_D1 3.0e-06
Ndufs5GOBP_Mitochondrial_Respiratory_Chain_Complex_AssemblyMouseSpinal cordL7CN47_D1 3.7e-06
Ndufs5GOBP_Nadh_Dehydrogenase_Complex_AssemblyMouseSpinal cordL7CN47_D1 2.6e-06
Ndufs5GOBP_Atp_Metabolic_ProcessMouseBrainrep_71 2.7e-06
Ndufs5GOBP_Atp_Synthesis_Coupled_Electron_TransportMouseBrainrep_71 1.2e-05
Ndufs5GOBP_Cellular_RespirationMouseBrainrep_71 1.7e-06
Ndufs5GOBP_Electron_Transport_ChainMouseBrainrep_71 2.4e-06
Ndufs5GOBP_Energy_Derivation_By_Oxidation_Of_Organic_CompoundsMouseBrainrep_71 3.4e-07
Ndufs5GOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseBrainrep_71 2.1e-06
Ndufs5GOBP_Mitochondrial_Electron_Transport_Nadh_To_UbiquinoneMouseBrainrep_71 2.1e-06
Ndufs5GOBP_Mitochondrial_Respiratory_Chain_Complex_AssemblyMouseBrainrep_71 2.8e-06
Ndufs5GOBP_Nadh_Dehydrogenase_Complex_AssemblyMouseBrainrep_71 3.5e-06
Ndufs5GOBP_Oxidative_PhosphorylationMouseBrainrep_71 5.5e-06
Ndufs5GOBP_Respiratory_Electron_Transport_ChainMouseBrainrep_71 1.2e-05
Ndufs5GOBP_Atp_Metabolic_ProcessMouseBrainrep_1 2.0e-14
Ndufs5GOBP_Atp_Synthesis_Coupled_Electron_TransportMouseBrainrep_1 7.9e-39
Ndufs5GOBP_Cellular_RespirationMouseBrainrep_1 9.5e-36
Ndufs5GOBP_Electron_Transport_ChainMouseBrainrep_1 1.3e-47
Ndufs5GOBP_Energy_Derivation_By_Oxidation_Of_Organic_CompoundsMouseBrainrep_1 1.1e-29
Ndufs5GOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseBrainrep_1 5.4e-15
Ndufs5GOBP_Mitochondrial_Electron_Transport_Nadh_To_UbiquinoneMouseBrainrep_1 1.2e-28
Ndufs5GOBP_Mitochondrial_Respiratory_Chain_Complex_AssemblyMouseBrainrep_1 5.0e-26
Ndufs5GOBP_Nadh_Dehydrogenase_Complex_AssemblyMouseBrainrep_1 9.2e-45
Ndufs5GOBP_Oxidative_PhosphorylationMouseBrainrep_1 7.5e-43
Ndufs5GOBP_Respiratory_Electron_Transport_ChainMouseBrainrep_1 4.5e-44
Ndufs5GOBP_Mitochondrion_OrganizationMouseBrainrep_3 1.3e-89
Ndufs5GOBP_Cellular_RespirationMouseEmbryorep_6 3.9e-08
Ndufs5GOBP_Atp_Metabolic_ProcessMouseEmbryorep_14 3.7e-37
Ndufs5GOBP_Atp_Synthesis_Coupled_Electron_TransportMouseEmbryorep_14 3.4e-58
Ndufs5GOBP_Electron_Transport_ChainMouseEmbryorep_14 5.7e-46
Ndufs5GOBP_Energy_Derivation_By_Oxidation_Of_Organic_CompoundsMouseEmbryorep_14 2.3e-31
Ndufs5GOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseEmbryorep_14 2.9e-37
Ndufs5GOBP_Mitochondrial_Electron_Transport_Nadh_To_UbiquinoneMouseEmbryorep_14 2.4e-71
Ndufs5GOBP_Mitochondrial_Respiratory_Chain_Complex_AssemblyMouseEmbryorep_14 5.0e-27
Ndufs5GOBP_Mitochondrion_OrganizationMouseEmbryorep_14 1.8e-11
Ndufs5GOBP_Nadh_Dehydrogenase_Complex_AssemblyMouseEmbryorep_14 2.8e-58
Ndufs5GOBP_Oxidative_PhosphorylationMouseEmbryorep_14 7.0e-41
Ndufs5GOBP_Respiratory_Electron_Transport_ChainMouseEmbryorep_14 8.9e-41
Ndufs5GOBP_Electron_Transport_ChainMouseEmbryorep_33.7e-124
Ndufs5GOBP_Mitochondrion_OrganizationMouseEmbryorep_3 4.0e-48
Ndufs5GOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseKidneyrep_2 3.3e-14
Ndufs5GOBP_Mitochondrion_OrganizationMouseKidneyrep_2 1.7e-21
Ndufs5GOBP_Mitochondrial_Electron_Transport_Nadh_To_UbiquinoneMouseLiverCN16-D1 1.6e-07
Ndufs5GOBP_Atp_Synthesis_Coupled_Electron_TransportMouseLiverCN65-C1 1.6e-09
Ndufs5GOBP_Atp_Metabolic_ProcessMouseLiverrep_16 1.2e-30
Ndufs5GOBP_Atp_Synthesis_Coupled_Electron_TransportMouseLiverrep_16 4.4e-24
Ndufs5GOBP_Cellular_RespirationMouseLiverrep_16 8.0e-25
Ndufs5GOBP_Electron_Transport_ChainMouseLiverrep_16 1.7e-16
Ndufs5GOBP_Energy_Derivation_By_Oxidation_Of_Organic_CompoundsMouseLiverrep_16 2.0e-28
Ndufs5GOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseLiverrep_16 7.4e-11
Ndufs5GOBP_Mitochondrial_Electron_Transport_Nadh_To_UbiquinoneMouseLiverrep_16 1.4e-13
Ndufs5GOBP_Mitochondrial_Respiratory_Chain_Complex_AssemblyMouseLiverrep_16 4.3e-23
Ndufs5GOBP_Nadh_Dehydrogenase_Complex_AssemblyMouseLiverrep_16 3.7e-23
Ndufs5GOBP_Oxidative_PhosphorylationMouseLiverrep_16 1.4e-27
Ndufs5GOBP_Respiratory_Electron_Transport_ChainMouseLiverrep_16 2.4e-29
Ndufs5GOBP_Atp_Synthesis_Coupled_Electron_TransportMouseIntestinerep_2 3.8e-16
Ndufs5GOBP_Electron_Transport_ChainMouseIntestinerep_2 8.8e-09
Ndufs5GOBP_Respiratory_Electron_Transport_ChainMouseIntestinerep_2 2.9e-16
Ndufs5GOBP_Mitochondrion_OrganizationMouseLymphMS-1 4.2e-09
Ndufs5GOBP_Atp_Synthesis_Coupled_Electron_TransportMouseLymphMS-2 8.2e-07
Ndufs5GOBP_Atp_Metabolic_ProcessMouseBrainHP_polb_rep9 1.0e-11
Ndufs5GOBP_Atp_Synthesis_Coupled_Electron_TransportMouseBrainHP_polb_rep9 4.5e-08
Ndufs5GOBP_Cellular_RespirationMouseBrainHP_polb_rep9 2.1e-07
Ndufs5GOBP_Electron_Transport_ChainMouseBrainHP_polb_rep9 5.9e-10
Ndufs5GOBP_Energy_Derivation_By_Oxidation_Of_Organic_CompoundsMouseBrainHP_polb_rep9 3.0e-10
Ndufs5GOBP_Generation_Of_Precursor_Metabolites_And_EnergyMouseBrainHP_polb_rep9 5.4e-11
Ndufs5GOBP_Mitochondrial_Electron_Transport_Nadh_To_UbiquinoneMouseBrainHP_polb_rep9 1.9e-08
Ndufs5GOBP_Mitochondrial_Respiratory_Chain_Complex_AssemblyMouseBrainHP_polb_rep9 7.2e-14
Ndufs5GOBP_Mitochondrion_OrganizationMouseBrainHP_polb_rep9 1.2e-11
Ndufs5GOBP_Nadh_Dehydrogenase_Complex_AssemblyMouseBrainHP_polb_rep9 1.3e-07
Ndufs5GOBP_Oxidative_PhosphorylationMouseBrainHP_polb_rep9 9.8e-11
Ndufs5GOBP_Respiratory_Electron_Transport_ChainMouseBrainHP_polb_rep9 1.8e-08

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Ndufs5 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Ndufs5 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Ndufs5 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Ndufs5

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Ndufs5

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource