SPASCER Logo

Home

Download & Upload

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Fxyd6 (spascer ID:59095)

Gene summary for Fxyd6

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Fxyd6

Gene ID

59095

Gene nameFXYD domain-containing ion transport regulator 6
Synonyms0610030I18Rik|Php
Cytomap9|9 A5.2
Type of geneprotein-coding
DescriptionFXYD domain-containing ion transport regulator 6PLM-like proteinphosphohippolin
Modification date20220510
UniProtAcc

Q9D164


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Fxyd6

GO:0017080

sodium channel regulator activity

21873635

Function
Fxyd6

GO:2000649

regulation of sodium ion transmembrane transporter activity

21873635

Process

Top

Spatial pattern events for Fxyd6

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Fxyd6MouseBrainS1 344135152.07e-15
Fxyd6MouseBrainS2 344135151.56e-15
Fxyd6MouseBrainS3 344135151.64e-15
Fxyd6MouseBrainS4 344135151.37e-15
Fxyd6MouseBrainS6 344135151.46e-15
Fxyd6MouseBrainS7 344135151.55e-15
Fxyd6MouseBrain03A 326376221.43e-09
Fxyd6MouseBrain03B 326376222.48e-06
Fxyd6MouseBrain04A 326376222.60e-10
Fxyd6MouseBrain04B 326376225.48e-14
Fxyd6MouseBrain05A 326376228.61e-14
Fxyd6MouseBrain05B 326376228.27e-12
Fxyd6MouseBrain06A 326376222.92e-06
Fxyd6MouseBrain06B 326376222.80e-14
Fxyd6MouseBrain07A 326376229.92e-07
Fxyd6MouseBrain07B 326376221.68e-08
Fxyd6MouseBrain09B 326376221.67e-06
Fxyd6MouseBrain10A 326376226.96e-06
Fxyd6MouseBrain11A 326376221.61e-14
Fxyd6MouseBrain12B 326376223.24e-07
Fxyd6MouseBrain13B 326376222.65e-07
Fxyd6MouseBrain14A 326376221.14e-08
Fxyd6MouseBrain14B 326376226.74e-09
Fxyd6MouseBrain15A 326376228.91e-07
Fxyd6MouseBrain17A 326376221.19e-14
Fxyd6MouseBrain17B 326376225.57e-10
Fxyd6MouseBrain18A 326376224.70e-07
Fxyd6MouseBrain18B 326376221.51e-11
Fxyd6MouseBrain19A 326376224.85e-10
Fxyd6MouseBrain19B 326376221.30e-11
Fxyd6MouseBrain20A 326376221.22e-10
Fxyd6MouseBrain20B 326376221.25e-10
Fxyd6MouseBrain21A 326376228.88e-11
Fxyd6MouseBrain21B 326376223.45e-08
Fxyd6MouseBrain22A 326376228.87e-15
Fxyd6MouseBrain22B 326376222.80e-14
Fxyd6MouseBrain23A 326376229.32e-11
Fxyd6MouseBrain23B 326376223.84e-12
Fxyd6MouseBrain24A 326376222.42e-09
Fxyd6MouseBrain24B 326376224.90e-11
Fxyd6MouseBrain25A 326376222.39e-06
Fxyd6MouseBrain26A 326376221.29e-08
Fxyd6MouseBrain26B 326376228.89e-06
Fxyd6MouseBrain27A 326376221.74e-14
Fxyd6MouseBrain27B 326376223.63e-09
Fxyd6MouseBrain28B 326376221.88e-07
Fxyd6MouseBrain29B 326376222.44e-09
Fxyd6MouseBrain34A 326376228.55e-13
Fxyd6MouseBrain34B 326376222.76e-06
Fxyd6MouseBrain36A 326376222.20e-06
Fxyd6MouseBrain38B 326376221.37e-06
Fxyd6MouseBrainrep_1 351413742.02e-15
Fxyd6MouseBrainrep_2 351413741.69e-15
Fxyd6MouseBrainrep_3 351413741.64e-15
Fxyd6MouseBrainrep_4 351413741.57e-15
Fxyd6MouseBrainrep_5 351413741.47e-15
Fxyd6MouseBrainrep_6 351413741.73e-15
Fxyd6MouseEmbryo1E 342108873.32e-07
Fxyd6MouseEmbryo1G 342108871.32e-07
Fxyd6MouseEmbryo2H 342108875.31e-15
Fxyd6MouseEmbryo3F 342108879.72e-10
Fxyd6MouseEmbryo4D 342108874.16e-07
Fxyd6MouseEmbryo4E 342108874.53e-15
Fxyd6MouseEmbryorep_4 331887762.26e-11
Fxyd6MouseKidneyCLP 340037972.19e-15
Fxyd6MouseKidneyIRI 340037976.29e-12
Fxyd6MouseKidneySham 340037972.58e-15
Fxyd6MouseBrainrep_1 334690251.30e-15
Fxyd6MouseBrainrep_1 350277291.66e-15
Fxyd6MouseBrainrep_2 350277291.57e-15
Fxyd6MouseBrainrep_3 350277291.32e-15
Fxyd6MouseBrainrep_4 350277291.76e-15
Fxyd6MouseBrainrep_5 350277291.46e-15
Fxyd6MouseIntestinerep_1 351497211.81e-14
Fxyd6MouseIntestinerep_2 351497213.44e-15
Fxyd6MouseIntestinerep_3 351497213.25e-15
Fxyd6MouseBrainB02_D1 327023142.50e-14
Fxyd6MouseBrainB02_E1 327023141.22e-13
Fxyd6MouseBrainB03_C2 327023141.59e-09
Fxyd6MouseBrainB03_D2 327023143.09e-06
Fxyd6MouseBrainB04_E1 327023141.33e-06
Fxyd6MouseBrainN02_C1 327023148.89e-14
Fxyd6MouseBrainN02_D1 327023141.64e-08
Fxyd6MouseBrainN03_C2 327023142.98e-13
Fxyd6MouseBrainN03_D2 327023141.38e-14
Fxyd6MouseBrainN05_C2 327023141.77e-11
Fxyd6MouseBrainN05_D2 327023141.92e-11
Fxyd6MouseLungrep_1 352908012.54e-10
Fxyd6MouseLungrep_3 352908015.26e-15
Fxyd6MouseBrainrep_1 352106241.74e-15
Fxyd6MouseBrainrep_2 352106241.74e-15
Fxyd6MouseBrainrep_3 352106241.82e-15
Fxyd6MouseBrainrep_4 352106242.34e-15
Fxyd6MouseBrainrep_5 352106242.07e-15
Fxyd6MouseBrainrep_6 352106242.05e-15
Fxyd6MouseBrainrep_7 352106241.87e-15
Fxyd6MouseBrainOFB_wt_rep5 330837254.67e-05

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
boxplot
boxplot
Brain_rep_2_H&E
boxplot
boxplot
Brain_rep_3_H&E
boxplot
boxplot
Brain_rep_4_H&E
boxplot
boxplot
Brain_rep_5_H&E
boxplot
boxplot
Brain_rep_6_H&E
boxplot
boxplot
Kidney_CLP_H&E
boxplot
boxplot
Kidney_IRI_H&E
boxplot
boxplot
Kidney_Sham_H&E
boxplot
boxplot
Brain_rep_1_H&E
boxplot
Brain_rep_1_H&E
boxplot
boxplot
Brain_rep_2_H&E
boxplot
boxplot
Brain_rep_3_H&E
boxplot
boxplot
Brain_rep_4_H&E
boxplot
boxplot
Brain_rep_5_H&E
boxplot
boxplot
Brain_B02_D1_H&E
boxplot
boxplot
Brain_B02_E1_H&E
boxplot
boxplot
Brain_B03_C2_H&E
boxplot
boxplot
Brain_B03_D2_H&E
boxplot
boxplot
Brain_B04_E1_H&E
boxplot
boxplot
Brain_N02_C1_H&E
boxplot
boxplot
Brain_N02_D1_H&E
boxplot
boxplot
Brain_N03_C2_H&E
boxplot
boxplot
Brain_N03_D2_H&E
boxplot
boxplot
Brain_N05_C2_H&E
boxplot
boxplot
Brain_N05_D2_H&E
boxplot
boxplot
Lung_rep_1_H&E
boxplot
boxplot
Lung_rep_3_H&E
boxplot
boxplot
Brain_OFB_wt_rep5_H&E
boxplot


Top

Spatial pattern pathway has Fxyd6 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Fxyd6GOBP_Cardiac_ConductionMouseSpinal cordCN94_E1 1.2e-06
Fxyd6GOBP_Cation_TransportMouseSpinal cordCN94_E1 5.8e-06
Fxyd6GOBP_Heart_ProcessMouseSpinal cordCN94_E1 1.2e-06
Fxyd6GOBP_Multicellular_Organismal_SignalingMouseSpinal cordCN94_E1 3.0e-07
Fxyd6GOBP_Regulation_Of_Blood_CirculationMouseSpinal cordCN94_E1 5.0e-06
Fxyd6GOBP_Regulation_Of_Cardiac_ConductionMouseSpinal cordCN94_E1 9.0e-06
Fxyd6GOBP_Regulation_Of_Cation_Transmembrane_TransportMouseSpinal cordCN94_E1 4.6e-06
Fxyd6GOBP_Regulation_Of_Heart_ContractionMouseSpinal cordCN94_E1 5.0e-06
Fxyd6GOBP_Regulation_Of_TransportMouseSpinal cordCN94_E1 5.3e-07
Fxyd6GOBP_Regulation_Of_Transporter_ActivityMouseSpinal cordCN94_E1 1.7e-06
Fxyd6GOBP_Cation_Transmembrane_TransportMouseSpinal cordL7CN45_C1 1.3e-08
Fxyd6GOBP_Inorganic_Ion_Transmembrane_TransportMouseSpinal cordL7CN45_C1 6.6e-07
Fxyd6GOBP_Regulation_Of_Ion_TransportMouseSpinal cordL7CN45_C1 3.6e-07
Fxyd6GOBP_Regulation_Of_Sodium_Ion_Transmembrane_TransportMouseSpinal cordL7CN45_C1 1.6e-07
Fxyd6GOBP_Regulation_Of_Sodium_Ion_TransportMouseSpinal cordL7CN45_C1 6.8e-06
Fxyd6GOBP_Regulation_Of_Transmembrane_TransportMouseSpinal cordL7CN45_C1 8.8e-08
Fxyd6GOBP_Sodium_Ion_Transmembrane_TransportMouseSpinal cordL7CN45_C1 6.8e-06
Fxyd6GOBP_Sodium_Ion_TransportMouseSpinal cordL7CN45_C1 7.7e-06
Fxyd6GOBP_Transmembrane_TransportMouseSpinal cordL7CN45_C1 3.5e-08
Fxyd6GOBP_Circulatory_System_ProcessMouseSpinal cordL8CN17_E1 2.2e-06
Fxyd6GOBP_Regulation_Of_System_ProcessMouseSpinal cordL8CN17_E1 7.2e-06
Fxyd6GOBP_Cardiac_ConductionMouseBrainrep_1 1.4e-81
Fxyd6GOBP_Cation_Transmembrane_TransportMouseBrainrep_1 4.4e-30
Fxyd6GOBP_Cation_TransportMouseBrainrep_1 1.5e-22
Fxyd6GOBP_Inorganic_Ion_Transmembrane_TransportMouseBrainrep_1 8.6e-24
Fxyd6GOBP_Multicellular_Organismal_SignalingMouseBrainrep_1 1.2e-19
Fxyd6GOBP_Regulation_Of_Cardiac_ConductionMouseBrainrep_1 1.5e-59
Fxyd6GOBP_Regulation_Of_Cation_Transmembrane_TransportMouseBrainrep_1 1.9e-25
Fxyd6GOBP_Regulation_Of_Heart_ContractionMouseBrainrep_1 1.5e-10
Fxyd6GOBP_Regulation_Of_Ion_TransportMouseBrainrep_1 8.9e-34
Fxyd6GOBP_Regulation_Of_Sodium_Ion_Transmembrane_TransportMouseBrainrep_1 2.5e-48
Fxyd6GOBP_Regulation_Of_Sodium_Ion_TransportMouseBrainrep_1 5.5e-53
Fxyd6GOBP_Regulation_Of_System_ProcessMouseBrainrep_1 4.2e-15
Fxyd6GOBP_Regulation_Of_Transmembrane_TransportMouseBrainrep_1 1.4e-17
Fxyd6GOBP_Regulation_Of_TransportMouseBrainrep_1 3.9e-15
Fxyd6GOBP_Regulation_Of_Transporter_ActivityMouseBrainrep_1 3.9e-25
Fxyd6GOBP_Sodium_Ion_Transmembrane_TransportMouseBrainrep_1 6.8e-45
Fxyd6GOBP_Sodium_Ion_TransportMouseBrainrep_1 4.4e-33
Fxyd6GOBP_Transmembrane_TransportMouseBrainrep_1 3.1e-23
Fxyd6GOBP_Regulation_Of_Blood_CirculationMouseBrainrep_2 1.1e-09
Fxyd6GOBP_Circulatory_System_ProcessMouseBrainrep_3 2.0e-61
Fxyd6GOBP_Heart_ProcessMouseBrainrep_3 1.6e-34
Fxyd6GOBP_Regulation_Of_Cardiac_ConductionMouseEmbryorep_14 2.3e-15
Fxyd6GOBP_Circulatory_System_ProcessMouseKidneyIRI 1.5e-08
Fxyd6GOBP_Regulation_Of_Blood_CirculationMouseKidneyIRI 1.6e-07
Fxyd6GOBP_Regulation_Of_Heart_ContractionMouseKidneyIRI 3.6e-08
Fxyd6GOBP_Regulation_Of_Transmembrane_TransportMouseKidneyNep 4.2e-26
Fxyd6GOBP_Regulation_Of_TransportMouseKidneyNep 2.6e-47
Fxyd6GOBP_Transmembrane_TransportMouseKidneyNep 4.2e-26
Fxyd6GOBP_Cardiac_ConductionMouseKidneyrep_2 6.2e-85
Fxyd6GOBP_Cation_Transmembrane_TransportMouseKidneyrep_2 7.3e-17
Fxyd6GOBP_Cation_TransportMouseKidneyrep_2 5.9e-23
Fxyd6GOBP_Circulatory_System_ProcessMouseKidneyrep_21.4e-100
Fxyd6GOBP_Heart_ProcessMouseKidneyrep_29.4e-105
Fxyd6GOBP_Inorganic_Ion_Transmembrane_TransportMouseKidneyrep_2 2.4e-15
Fxyd6GOBP_Multicellular_Organismal_SignalingMouseKidneyrep_21.9e-111
Fxyd6GOBP_Regulation_Of_Blood_CirculationMouseKidneyrep_23.3e-107
Fxyd6GOBP_Regulation_Of_Cation_Transmembrane_TransportMouseKidneyrep_2 1.0e-96
Fxyd6GOBP_Regulation_Of_Heart_ContractionMouseKidneyrep_23.8e-105
Fxyd6GOBP_Regulation_Of_Ion_TransportMouseKidneyrep_25.5e-106
Fxyd6GOBP_Regulation_Of_Sodium_Ion_Transmembrane_TransportMouseKidneyrep_2 2.4e-76
Fxyd6GOBP_Regulation_Of_Sodium_Ion_TransportMouseKidneyrep_2 1.0e-86
Fxyd6GOBP_Regulation_Of_System_ProcessMouseKidneyrep_2 3.2e-62
Fxyd6GOBP_Regulation_Of_Transmembrane_TransportMouseKidneyrep_22.0e-115
Fxyd6GOBP_Regulation_Of_TransportMouseKidneyrep_2 2.4e-58
Fxyd6GOBP_Regulation_Of_Transporter_ActivityMouseKidneyrep_2 4.8e-85
Fxyd6GOBP_Sodium_Ion_Transmembrane_TransportMouseKidneyrep_22.6e-108
Fxyd6GOBP_Sodium_Ion_TransportMouseKidneyrep_2 2.5e-82
Fxyd6GOBP_Transmembrane_TransportMouseKidneyrep_2 2.7e-23
Fxyd6GOBP_Regulation_Of_Heart_ContractionMouseLiverCN16-E1 2.4e-08
Fxyd6GOBP_Cardiac_ConductionMouseLiverCN65-C1 4.7e-07
Fxyd6GOBP_Multicellular_Organismal_SignalingMouseLiverCN65-C1 1.0e-07
Fxyd6GOBP_Regulation_Of_TransportMouseLiverCN73-C1 1.8e-07
Fxyd6GOBP_Cation_Transmembrane_TransportMouseLiverrep_15 8.9e-14
Fxyd6GOBP_Inorganic_Ion_Transmembrane_TransportMouseLiverrep_15 2.4e-07
Fxyd6GOBP_Regulation_Of_Cation_Transmembrane_TransportMouseLiverrep_15 5.9e-09
Fxyd6GOBP_Cardiac_ConductionMouseLiverrep_16 5.5e-07
Fxyd6GOBP_Cation_TransportMouseLiverrep_16 1.2e-18
Fxyd6GOBP_Multicellular_Organismal_SignalingMouseLiverrep_16 5.2e-24
Fxyd6GOBP_Regulation_Of_Blood_CirculationMouseLiverrep_16 5.6e-22
Fxyd6GOBP_Regulation_Of_Cardiac_ConductionMouseLiverrep_16 1.4e-33
Fxyd6GOBP_Regulation_Of_Sodium_Ion_TransportMouseLiverrep_16 1.2e-10
Fxyd6GOBP_Sodium_Ion_Transmembrane_TransportMouseLiverrep_16 6.2e-12
Fxyd6GOBP_Sodium_Ion_TransportMouseLiverrep_16 5.5e-14
Fxyd6GOBP_Transmembrane_TransportMouseLiverrep_16 1.4e-13
Fxyd6GOBP_Regulation_Of_Transporter_ActivityMouseLiverrep_23 4.6e-19
Fxyd6GOBP_Circulatory_System_ProcessMouseLymphMS-1 3.9e-08
Fxyd6GOBP_Heart_ProcessMouseLymphMS-1 1.3e-13
Fxyd6GOBP_Multicellular_Organismal_SignalingMouseLymphMS-1 1.0e-09
Fxyd6GOBP_Regulation_Of_Blood_CirculationMouseLymphMS-1 3.2e-09
Fxyd6GOBP_Regulation_Of_Cation_Transmembrane_TransportMouseLymphMS-1 1.1e-12
Fxyd6GOBP_Regulation_Of_Ion_TransportMouseLymphMS-1 1.5e-09
Fxyd6GOBP_Regulation_Of_Sodium_Ion_TransportMouseLymphMS-1 2.8e-07
Fxyd6GOBP_Regulation_Of_System_ProcessMouseLymphMS-1 1.8e-07
Fxyd6GOBP_Regulation_Of_Transmembrane_TransportMouseLymphMS-1 3.3e-13
Fxyd6GOBP_Regulation_Of_TransportMouseLymphMS-1 1.4e-12
Fxyd6GOBP_Regulation_Of_Transporter_ActivityMouseLymphMS-1 3.9e-12
Fxyd6GOBP_Sodium_Ion_TransportMouseLymphMS-1 2.5e-07
Fxyd6GOBP_Regulation_Of_Cardiac_ConductionMouseLymphMS-2 5.3e-10
Fxyd6GOBP_Regulation_Of_Blood_CirculationMouseBrainrep_4 2.3e-07
Fxyd6GOBP_Regulation_Of_Cardiac_ConductionMouseBrainrep_4 2.4e-50
Fxyd6GOBP_Regulation_Of_Sodium_Ion_Transmembrane_TransportMouseBrainrep_4 4.5e-65
Fxyd6GOBP_Regulation_Of_Sodium_Ion_TransportMouseBrainrep_4 5.1e-42
Fxyd6GOBP_Sodium_Ion_Transmembrane_TransportMouseBrainrep_4 5.0e-57
Fxyd6GOBP_Sodium_Ion_TransportMouseBrainrep_4 1.4e-55
Fxyd6GOBP_Cation_TransportMouseBrainHP_ad_rep7 7.5e-07
Fxyd6GOBP_Regulation_Of_Transmembrane_TransportMouseBrainHP_ad_rep7 1.5e-07
Fxyd6GOBP_Regulation_Of_TransportMouseBrainHP_ad_rep7 9.2e-09
Fxyd6GOBP_Transmembrane_TransportMouseBrainHP_ad_rep7 3.4e-07
Fxyd6GOBP_Cation_Transmembrane_TransportMouseBrainHP_polb_rep9 1.4e-07
Fxyd6GOBP_Circulatory_System_ProcessMouseBrainHP_polb_rep9 5.3e-09
Fxyd6GOBP_Heart_ProcessMouseBrainHP_polb_rep9 9.9e-09
Fxyd6GOBP_Inorganic_Ion_Transmembrane_TransportMouseBrainHP_polb_rep9 1.1e-07
Fxyd6GOBP_Regulation_Of_Heart_ContractionMouseBrainHP_polb_rep9 8.6e-07
Fxyd6GOBP_Regulation_Of_Sodium_Ion_Transmembrane_TransportMouseBrainHP_polb_rep9 3.9e-07
Fxyd6GOBP_Regulation_Of_System_ProcessMouseBrainHP_polb_rep9 9.3e-08
Fxyd6GOBP_Sodium_Ion_Transmembrane_TransportMouseBrainHP_polb_rep9 3.5e-08

Top

Fxyd6 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

Top

Fxyd6 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

Top

Transcription factor for Fxyd6 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

Top

Related Drugs for Fxyd6

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for Fxyd6

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Fxyd6C0036341Schizophrenia5PSYGENET
Fxyd6C0023467Leukemia, Myelocytic, Acute1CTD_human
Fxyd6C0023893Liver Cirrhosis, Experimental1CTD_human
Fxyd6C0026998Acute Myeloid Leukemia, M11CTD_human
Fxyd6C1879321Acute Myeloid Leukemia (AML-M2)1CTD_human