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Spatial pattern gene: Nsa2 (spascer ID:59050) |
Gene summary for Nsa2 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Nsa2 | Gene ID | 59050 |
| Gene name | NSA2 ribosome biogenesis homolog |
| Synonyms | 5730427N09Rik|LNR42|Nsa2p|Tinp1|Yr29 |
| Cytomap | 13|13 D1 |
| Type of gene | protein-coding |
| Description | ribosome biogenesis protein NSA2 homologL-name related proteinL-name-related protein 42TGF-beta-inducible nuclear protein 1 |
| Modification date | 20220424 |
| UniProtAcc | Q9CR47 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Nsa2 | GO:0000460 | maturation of 5.8S rRNA | 21873635 | Process |
| Nsa2 | GO:0000470 | maturation of LSU-rRNA | 21873635 | Process |
| Nsa2 | GO:0030687 | preribosome, large subunit precursor | 21873635 | Component |
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Spatial pattern events for Nsa2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Nsa2 | Mouse | Brain | S1 | 34413515 | 5.51e-08 |
| Nsa2 | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Nsa2 | Mouse | Brain | S4 | 34413515 | 1.22e-07 |
| Nsa2 | Mouse | Brain | S6 | 34413515 | 8.34e-14 |
| Nsa2 | Mouse | Brain | S7 | 34413515 | 2.85e-15 |
| Nsa2 | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Nsa2 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Nsa2 | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Nsa2 | Mouse | Kidney | Sham | 34003797 | 1.50e-06 |
| Nsa2 | Mouse | Kidney | rep_1 | 34853151 | 6.58e-09 |
| Nsa2 | Mouse | Kidney | rep_5 | 34853151 | 3.11e-08 |
| Nsa2 | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Nsa2 | Mouse | Liver | rep_23 | 35021063 | 1.19e-08 |
| Nsa2 | Mouse | Intestine | rep_3 | 35149721 | 1.67e-06 |
| Nsa2 | Mouse | Intestine | rep_4 | 35149721 | 4.70e-06 |
| Nsa2 | Mouse | Lung | rep_1 | 35290801 | 1.80e-08 |
| Nsa2 | Mouse | Lung | rep_4 | 35290801 | 5.40e-15 |
| Nsa2 | Mouse | Brain | rep_5 | 35210624 | 1.02e-07 |
| Nsa2 | Mouse | Brain | rep_6 | 35210624 | 2.71e-14 |
| Nsa2 | Mouse | Brain | rep_7 | 35210624 | 6.25e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Liver_rep_23_H&E  | |
Lung_rep_1_H&E  |  |
Lung_rep_4_H&E  |  |
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Spatial pattern pathway has Nsa2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Nsa2 | GOBP_Ncrna_Metabolic_Process | Mouse | Spinal cord | L7CN45_C1 | 1.5e-07 |
| Nsa2 | GOBP_Ncrna_Processing | Mouse | Spinal cord | L7CN45_C1 | 1.4e-06 |
| Nsa2 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Mouse | Spinal cord | L7CN45_C1 | 1.4e-06 |
| Nsa2 | GOBP_Ribosomal_Large_Subunit_Biogenesis | Mouse | Spinal cord | L7CN45_C1 | 5.4e-07 |
| Nsa2 | GOBP_Ribosome_Biogenesis | Mouse | Spinal cord | L7CN45_C1 | 1.4e-06 |
| Nsa2 | GOBP_Rna_Processing | Mouse | Spinal cord | L7CN45_C1 | 2.2e-09 |
| Nsa2 | GOBP_Rrna_Metabolic_Process | Mouse | Spinal cord | L7CN45_C1 | 6.3e-07 |
| Nsa2 | GOBP_Maturation_Of_5_8s_Rrna | Mouse | Spinal cord | L7CN47_D1 | 1.7e-07 |
| Nsa2 | GOBP_Maturation_Of_5_8s_Rrna | Mouse | Brain | rep_27 | 4.2e-07 |
| Nsa2 | GOBP_Maturation_Of_5_8s_Rrna | Mouse | Brain | rep_3 | 4.7e-18 |
| Nsa2 | GOBP_Maturation_Of_Lsu_Rrna | Mouse | Brain | rep_3 | 1.0e-150 |
| Nsa2 | GOBP_Ncrna_Metabolic_Process | Mouse | Brain | rep_3 | 1.8e-46 |
| Nsa2 | GOBP_Ncrna_Processing | Mouse | Brain | rep_3 | 5.1e-21 |
| Nsa2 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Mouse | Brain | rep_3 | 5.6e-32 |
| Nsa2 | GOBP_Ribosomal_Large_Subunit_Biogenesis | Mouse | Brain | rep_3 | 2.0e-16 |
| Nsa2 | GOBP_Ribosome_Biogenesis | Mouse | Brain | rep_3 | 1.8e-14 |
| Nsa2 | GOBP_Rna_Processing | Mouse | Brain | rep_3 | 4.3e-140 |
| Nsa2 | GOBP_Rrna_Metabolic_Process | Mouse | Brain | rep_3 | 1.7e-24 |
| Nsa2 | GOBP_Maturation_Of_5_8s_Rrna | Mouse | Embryo | rep_14 | 4.0e-23 |
| Nsa2 | GOBP_Maturation_Of_Lsu_Rrna | Mouse | Embryo | rep_14 | 1.4e-39 |
| Nsa2 | GOBP_Ncrna_Processing | Mouse | Embryo | rep_14 | 2.7e-41 |
| Nsa2 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Mouse | Embryo | rep_14 | 2.1e-33 |
| Nsa2 | GOBP_Ribosomal_Large_Subunit_Biogenesis | Mouse | Embryo | rep_14 | 3.3e-47 |
| Nsa2 | GOBP_Ribosome_Biogenesis | Mouse | Embryo | rep_14 | 2.1e-33 |
| Nsa2 | GOBP_Rna_Processing | Mouse | Embryo | rep_14 | 3.5e-14 |
| Nsa2 | GOBP_Rrna_Metabolic_Process | Mouse | Embryo | rep_14 | 2.2e-54 |
| Nsa2 | GOBP_Rna_Processing | Mouse | Embryo | rep_2 | 2.4e-14 |
| Nsa2 | GOBP_Maturation_Of_5_8s_Rrna | Mouse | Kidney | rep_2 | 4.9e-67 |
| Nsa2 | GOBP_Maturation_Of_Lsu_Rrna | Mouse | Kidney | rep_2 | 1.8e-61 |
| Nsa2 | GOBP_Ncrna_Metabolic_Process | Mouse | Kidney | rep_2 | 6.2e-81 |
| Nsa2 | GOBP_Ncrna_Processing | Mouse | Kidney | rep_2 | 5.7e-81 |
| Nsa2 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Mouse | Kidney | rep_2 | 1.3e-69 |
| Nsa2 | GOBP_Ribosomal_Large_Subunit_Biogenesis | Mouse | Kidney | rep_2 | 5.3e-71 |
| Nsa2 | GOBP_Ribosome_Biogenesis | Mouse | Kidney | rep_2 | 2.5e-90 |
| Nsa2 | GOBP_Rna_Processing | Mouse | Kidney | rep_2 | 1.1e-71 |
| Nsa2 | GOBP_Rrna_Metabolic_Process | Mouse | Kidney | rep_2 | 6.8e-87 |
| Nsa2 | GOBP_Ncrna_Metabolic_Process | Mouse | Liver | CN73-C1 | 1.4e-08 |
| Nsa2 | GOBP_Maturation_Of_5_8s_Rrna | Mouse | Lymph | MS-1 | 2.6e-10 |
| Nsa2 | GOBP_Maturation_Of_Lsu_Rrna | Mouse | Lymph | MS-1 | 1.3e-08 |
| Nsa2 | GOBP_Ncrna_Metabolic_Process | Mouse | Lymph | MS-1 | 1.4e-09 |
| Nsa2 | GOBP_Ncrna_Processing | Mouse | Lymph | MS-1 | 7.2e-09 |
| Nsa2 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Mouse | Lymph | MS-1 | 1.7e-07 |
| Nsa2 | GOBP_Ribosome_Biogenesis | Mouse | Lymph | MS-1 | 8.8e-09 |
| Nsa2 | GOBP_Rna_Processing | Mouse | Lymph | MS-1 | 2.0e-09 |
| Nsa2 | GOBP_Rrna_Metabolic_Process | Mouse | Lymph | MS-1 | 7.1e-07 |
| Nsa2 | GOBP_Maturation_Of_5_8s_Rrna | Mouse | Brain | HP_ad_rep7 | 4.7e-08 |
| Nsa2 | GOBP_Ncrna_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 5.9e-10 |
| Nsa2 | GOBP_Ribonucleoprotein_Complex_Biogenesis | Mouse | Brain | HP_ad_rep7 | 7.9e-07 |
| Nsa2 | GOBP_Ribosomal_Large_Subunit_Biogenesis | Mouse | Brain | HP_ad_rep7 | 7.8e-07 |
| Nsa2 | GOBP_Ribosome_Biogenesis | Mouse | Brain | HP_ad_rep7 | 1.6e-08 |
| Nsa2 | GOBP_Rna_Processing | Mouse | Brain | HP_ad_rep7 | 2.7e-09 |
| Nsa2 | GOBP_Ncrna_Processing | Mouse | Brain | HP_adpolb_rep1 | 3.5e-08 |
| Nsa2 | GOBP_Rrna_Metabolic_Process | Mouse | Brain | HP_adpolb_rep1 | 2.6e-13 |
| Nsa2 | GOBP_Maturation_Of_Lsu_Rrna | Mouse | Brain | HP_adpolb_rep6 | 7.9e-09 |
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Nsa2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Nsa2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Nsa2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Nsa2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Nsa2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Nsa2 | C0008312 | Primary biliary cirrhosis | 1 | CTD_human |
| Nsa2 | C0023892 | Biliary cirrhosis | 1 | CTD_human |
| Nsa2 | C0238065 | Secondary Biliary Cholangitis | 1 | CTD_human |
| Nsa2 | C4551595 | Biliary Cirrhosis, Primary, 1 | 1 | CTD_human |
