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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Rnf130 (spascer ID:59044)

Gene summary for Rnf130

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Rnf130
	Gene ID	59044
	Gene name	ring finger protein 130
	Synonyms	2510042A13Rik\|G1RZFP\|G1rp\|GOLIATH\|GP
	Cytomap	11\|11 B1.3
	Type of gene	protein-coding
	Description	E3 ubiquitin-protein ligase RNF130RING-type E3 ubiquitin transferase RNF130g1-related zinc finger proteingoliath homolog
	Modification date	20220424
	UniProtAcc	Q8VEM1

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Rnf130	GO:0005737	cytoplasm	21873635	Component
Rnf130	GO:0006511	ubiquitin-dependent protein catabolic process	21873635	Process
Rnf130	GO:0061630	ubiquitin protein ligase activity	21873635	Function

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Spatial pattern events for Rnf130

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Rnf130	Mouse	Brain	S1	34413515	2.07e-15
Rnf130	Mouse	Brain	S2	34413515	1.56e-15
Rnf130	Mouse	Brain	S3	34413515	1.64e-15
Rnf130	Mouse	Brain	S4	34413515	1.37e-15
Rnf130	Mouse	Brain	S6	34413515	1.46e-15
Rnf130	Mouse	Brain	S7	34413515	1.55e-15
Rnf130	Mouse	Brain	12B	32637622	2.64e-11
Rnf130	Mouse	Brain	14A	32637622	3.58e-07
Rnf130	Mouse	Brain	22B	32637622	2.05e-07
Rnf130	Mouse	Brain	27A	32637622	1.23e-09
Rnf130	Mouse	Brain	27B	32637622	6.70e-09
Rnf130	Mouse	Brain	28A	32637622	8.87e-08
Rnf130	Mouse	Brain	28B	32637622	2.22e-07
Rnf130	Mouse	Brain	29A	32637622	1.74e-09
Rnf130	Mouse	Brain	29B	32637622	7.34e-11
Rnf130	Mouse	Brain	32A	32637622	1.11e-06
Rnf130	Mouse	Brain	33A	32637622	6.94e-09
Rnf130	Mouse	Brain	34B	32637622	2.83e-06
Rnf130	Mouse	Brain	35A	32637622	4.25e-09
Rnf130	Mouse	Brain	rep_1	35141374	1.89e-08
Rnf130	Mouse	Brain	rep_2	35141374	1.69e-15
Rnf130	Mouse	Brain	rep_3	35141374	3.00e-15
Rnf130	Mouse	Brain	rep_4	35141374	1.36e-06
Rnf130	Mouse	Brain	rep_5	35141374	1.47e-15
Rnf130	Mouse	Brain	rep_6	35141374	1.73e-15
Rnf130	Mouse	Kidney	CLP	34003797	2.19e-15
Rnf130	Mouse	Kidney	Sham	34003797	2.20e-09
Rnf130	Mouse	Brain	rep_1	33469025	7.50e-13
Rnf130	Mouse	Brain	rep_1	35027729	1.66e-15
Rnf130	Mouse	Brain	rep_2	35027729	1.57e-15
Rnf130	Mouse	Brain	rep_3	35027729	1.32e-15
Rnf130	Mouse	Brain	rep_4	35027729	1.76e-15
Rnf130	Mouse	Brain	rep_5	35027729	1.46e-15
Rnf130	Mouse	Testicle	rep_3	34731600	3.25e-15
Rnf130	Mouse	Lymph	A1	0	5.06e-12
Rnf130	Mouse	Lymph	B1	0	7.43e-14
Rnf130	Mouse	Lung	rep_3	35290801	5.03e-06
Rnf130	Mouse	Brain	rep_1	35210624	3.17e-15
Rnf130	Mouse	Brain	rep_2	35210624	1.74e-15
Rnf130	Mouse	Brain	rep_3	35210624	1.82e-15
Rnf130	Mouse	Brain	rep_5	35210624	2.07e-15
Rnf130	Mouse	Brain	rep_6	35210624	2.05e-15
Rnf130	Mouse	Brain	rep_7	35210624	1.87e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_Sham_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_3_H&E

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Spatial pattern pathway has Rnf130 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Rnf130	GOBP_Macromolecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	7.5e-06
Rnf130	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Rnf130	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Rnf130	GOBP_Protein_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Rnf130	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Rnf130	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Brain	rep_3	2.9e-162
Rnf130	GOBP_Macromolecule_Catabolic_Process	Mouse	Brain	rep_3	1.7e-159
Rnf130	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Brain	rep_3	8.7e-167
Rnf130	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	rep_3	7.1e-166
Rnf130	GOBP_Protein_Catabolic_Process	Mouse	Brain	rep_3	3.0e-174
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Brain	rep_3	1.4e-184
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Brain	rep_3	6.3e-190
Rnf130	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
Rnf130	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Embryo	rep_1	7.5e-10
Rnf130	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Embryo	rep_1	5.7e-21
Rnf130	GOBP_Protein_Catabolic_Process	Mouse	Embryo	rep_1	4.1e-19
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Embryo	rep_1	4.4e-16
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Embryo	rep_3	4.2e-21
Rnf130	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
Rnf130	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Kidney	rep_2	3.2e-21
Rnf130	GOBP_Macromolecule_Catabolic_Process	Mouse	Kidney	rep_2	7.0e-40
Rnf130	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Kidney	rep_2	1.0e-26
Rnf130	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Kidney	rep_2	1.2e-14
Rnf130	GOBP_Protein_Catabolic_Process	Mouse	Kidney	rep_2	7.3e-30
Rnf130	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
Rnf130	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
Rnf130	GOBP_Macromolecule_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Rnf130	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
Rnf130	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Rnf130	GOBP_Protein_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Lymph	MS-1	1.4e-09
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Lymph	MS-1	1.4e-09
Rnf130	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
Rnf130	GOBP_Macromolecule_Catabolic_Process	Mouse	Lung	rep_1	2.0e-21
Rnf130	GOBP_Macromolecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-09
Rnf130	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-08
Rnf130	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Rnf130	GOBP_Protein_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Brain	HP_ad_rep7	1.7e-09
Rnf130	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Brain	HP_ad_rep7	6.9e-09
Rnf130	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
Rnf130	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Brain	HP_adpolb_rep1	7.2e-07

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Rnf130 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Rnf130 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Rnf130 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Rnf130

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Rnf130

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Rnf130	C0033578	Prostatic Neoplasms	1	CTD_human
Rnf130	C0376358	Malignant neoplasm of prostate	1	CTD_human