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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Smarce1 (spascer ID:57376)

Gene summary for Smarce1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Smarce1
	Gene ID	57376
	Gene name	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
	Synonyms	2810417B20Rik\|5830412H02Rik\|9030408N19Rik\|Baf27
	Cytomap	11\|11 D
	Type of gene	protein-coding
	Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1BAF57BRG1-associated factor 57SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1
	Modification date	20220424
	UniProtAcc	O54941

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Smarce1	GO:0016514	SWI/SNF complex	21873635	Component
Smarce1	GO:0016922	nuclear receptor binding	21873635	Function
Smarce1	GO:0045892	negative regulation of transcription, DNA-templated	21873635	Process

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Spatial pattern events for Smarce1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Smarce1	Mouse	Embryo	rep_4	33188776	9.44e-11
Smarce1	Mouse	Embryo	rep_5	33188776	3.86e-14
Smarce1	Mouse	Brain	rep_1	33469025	1.30e-15
Smarce1	Mouse	Intestine	rep_4	35149721	2.30e-15
Smarce1	Mouse	Testicle	rep_4	34731600	1.62e-14
Smarce1	Mouse	Lymph	A1	0	3.03e-08
Smarce1	Mouse	Lymph	B1	0	7.43e-14
Smarce1	Mouse	Lung	rep_2	35290801	1.05e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Lung_rep_2_H&E

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Spatial pattern pathway has Smarce1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Smarce1	GOBP_Chromatin_Disassembly	Mouse	Spinal cord	CN94_E1	1.9e-06
Smarce1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	1.6e-06
Smarce1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	CN94_E1	6.2e-07
Smarce1	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Spinal cord	CN94_E1	5.8e-06
Smarce1	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Spinal cord	CN94_E1	4.2e-07
Smarce1	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Spinal cord	L7bCN02_E1	3.4e-06
Smarce1	GOBP_Cellular_Component_Disassembly	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Smarce1	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Smarce1	GOBP_Chromatin_Organization	Mouse	Spinal cord	L7CN45_C1	3.5e-07
Smarce1	GOBP_Chromatin_Remodeling	Mouse	Spinal cord	L7CN45_C1	4.5e-06
Smarce1	GOBP_Chromosome_Organization	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Smarce1	GOBP_Neurogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Smarce1	GOBP_Nucleosome_Organization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Smarce1	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Brain	rep_19	1.5e-05
Smarce1	GOBP_Nucleosome_Organization	Mouse	Brain	rep_19	1.2e-06
Smarce1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_27	7.2e-05
Smarce1	GOBP_Cellular_Component_Disassembly	Mouse	Brain	rep_1	1.5e-15
Smarce1	GOBP_Chromatin_Disassembly	Mouse	Brain	rep_1	1.1e-08
Smarce1	GOBP_Chromosome_Organization	Mouse	Brain	rep_1	3.9e-07
Smarce1	GOBP_Neurogenesis	Mouse	Brain	rep_1	6.4e-19
Smarce1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_1	2.5e-12
Smarce1	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Brain	rep_1	4.1e-29
Smarce1	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Brain	rep_3	1.7e-35
Smarce1	GOBP_Chromatin_Organization	Mouse	Brain	rep_3	5.1e-215
Smarce1	GOBP_Chromatin_Remodeling	Mouse	Brain	rep_3	4.4e-194
Smarce1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_3	1.4e-196
Smarce1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_3	9.4e-206
Smarce1	GOBP_Nucleosome_Organization	Mouse	Brain	rep_3	1.5e-62
Smarce1	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Brain	rep_3	1.4e-131
Smarce1	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Brain	rep_3	5.3e-122
Smarce1	GOBP_Chromatin_Disassembly	Mouse	Embryo	rep_14	7.8e-13
Smarce1	GOBP_Nucleosome_Organization	Mouse	Embryo	rep_14	1.7e-10
Smarce1	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Embryo	rep_14	1.2e-31
Smarce1	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Embryo	rep_14	2.2e-11
Smarce1	GOBP_Neurogenesis	Mouse	Embryo	rep_1	8.2e-08
Smarce1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Embryo	rep_2	8.0e-13
Smarce1	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Embryo	rep_3	4.5e-65
Smarce1	GOBP_Chromatin_Organization	Mouse	Embryo	rep_3	2.9e-87
Smarce1	GOBP_Chromosome_Organization	Mouse	Embryo	rep_3	1.4e-57
Smarce1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	1.5e-267
Smarce1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Smarce1	GOBP_Neurogenesis	Mouse	Kidney	Nep	4.6e-22
Smarce1	GOBP_Cellular_Component_Disassembly	Mouse	Kidney	rep_2	4.2e-70
Smarce1	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Kidney	rep_2	1.1e-38
Smarce1	GOBP_Chromatin_Disassembly	Mouse	Kidney	rep_2	2.2e-34
Smarce1	GOBP_Chromatin_Organization	Mouse	Kidney	rep_2	3.0e-63
Smarce1	GOBP_Chromosome_Organization	Mouse	Kidney	rep_2	1.0e-14
Smarce1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Kidney	rep_2	7.3e-42
Smarce1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	7.7e-30
Smarce1	GOBP_Neurogenesis	Mouse	Kidney	rep_2	2.4e-78
Smarce1	GOBP_Nucleosome_Organization	Mouse	Kidney	rep_2	4.7e-25
Smarce1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	4.5e-10
Smarce1	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Kidney	rep_2	1.4e-54
Smarce1	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Kidney	rep_2	1.6e-30
Smarce1	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Kidney	rep_2	1.1e-35
Smarce1	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Liver	CN16-D1	9.0e-08
Smarce1	GOBP_Nucleosome_Organization	Mouse	Liver	CN65-C1	1.6e-09
Smarce1	GOBP_Chromatin_Disassembly	Mouse	Liver	rep_15	8.9e-26
Smarce1	GOBP_Cellular_Component_Disassembly	Mouse	Lymph	MS-1	2.4e-16
Smarce1	GOBP_Chromatin_Organization	Mouse	Lymph	MS-1	9.1e-11
Smarce1	GOBP_Chromosome_Organization	Mouse	Lymph	MS-1	3.5e-09
Smarce1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-11
Smarce1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	1.8e-10
Smarce1	GOBP_Neurogenesis	Mouse	Lymph	MS-1	4.1e-08
Smarce1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Smarce1	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Lymph	MS-1	5.5e-11
Smarce1	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Lymph	MS-1	2.3e-07
Smarce1	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Lymph	MS-1	2.3e-09
Smarce1	GOBP_Chromatin_Disassembly	Mouse	Lymph	PBS	6.0e-07
Smarce1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lung	rep_1	7.5e-20
Smarce1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lung	rep_1	5.8e-10
Smarce1	GOBP_Chromatin_Assembly_Or_Disassembly	Mouse	Brain	HP_ad_rep7	6.7e-07
Smarce1	GOBP_Chromatin_Disassembly	Mouse	Brain	HP_ad_rep7	3.1e-08
Smarce1	GOBP_Chromatin_Organization	Mouse	Brain	HP_ad_rep7	7.6e-11
Smarce1	GOBP_Chromatin_Remodeling	Mouse	Brain	HP_ad_rep7	5.3e-11
Smarce1	GOBP_Chromosome_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Smarce1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.3e-12
Smarce1	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-11
Smarce1	GOBP_Neurogenesis	Mouse	Brain	HP_ad_rep7	3.9e-07
Smarce1	GOBP_Nucleosome_Organization	Mouse	Brain	HP_ad_rep7	6.7e-07
Smarce1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-11
Smarce1	GOBP_Protein_Dna_Complex_Subunit_Organization	Mouse	Brain	HP_ad_rep7	9.8e-13
Smarce1	GOBP_Protein_Dna_Complex_Disassembly	Mouse	Brain	HP_adpolb_rep5	3.5e-12
Smarce1	GOBP_Cellular_Component_Disassembly	Mouse	Brain	HP_polb_rep9	3.4e-08
Smarce1	GOBP_Protein_Containing_Complex_Disassembly	Mouse	Brain	HP_polb_rep9	1.8e-08

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Smarce1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Smarce1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Smarce1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Smarce1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Smarce1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Smarce1	C0265338	Coffin-Siris syndrome	3	CTD_human;GENOMICS_ENGLAND;ORPHANET
Smarce1	C4310788	COFFIN-SIRIS SYNDROME 5	2	UNIPROT
Smarce1	C0010606	Adenoid Cystic Carcinoma	1	CTD_human
Smarce1	C1333989	Familial meningioma	1	CTD_human
Smarce1	C3281201	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	1	GENOMICS_ENGLAND