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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Mbnl1 (spascer ID:56758)

Gene summary for Mbnl1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Mbnl1
	Gene ID	56758
	Gene name	muscleblind like splicing factor 1
	Synonyms	Mbnl\|mKIAA0428
	Cytomap	3\|3 D
	Type of gene	protein-coding
	Description	muscleblind-like protein 1muscleblind-like 1triplet-expansion RNA-binding protein
	Modification date	20220503
	UniProtAcc	Q9JKP5

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Mbnl1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	21873635	Process
Mbnl1	GO:0003723	RNA binding	21873635	Function
Mbnl1	GO:0005654	nucleoplasm	21873635	Component
Mbnl1	GO:0005737	cytoplasm	21873635	Component

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Spatial pattern events for Mbnl1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Mbnl1	Mouse	Brain	S1	34413515	6.94e-06
Mbnl1	Mouse	Brain	S4	34413515	4.95e-10
Mbnl1	Mouse	Brain	05A	32637622	4.27e-06
Mbnl1	Mouse	Brain	06B	32637622	8.00e-07
Mbnl1	Mouse	Brain	29A	32637622	5.07e-08
Mbnl1	Mouse	Brain	29B	32637622	1.10e-06
Mbnl1	Mouse	Brain	30A	32637622	3.53e-11
Mbnl1	Mouse	Embryo	1E	34210887	3.01e-09
Mbnl1	Mouse	Embryo	1F	34210887	9.86e-11
Mbnl1	Mouse	Embryo	2G	34210887	4.93e-09
Mbnl1	Mouse	Embryo	3D	34210887	6.70e-08
Mbnl1	Mouse	Embryo	3F	34210887	1.68e-09
Mbnl1	Mouse	Embryo	4E	34210887	3.83e-11
Mbnl1	Mouse	Embryo	rep_1	33188776	9.94e-15
Mbnl1	Mouse	Embryo	rep_4	33188776	5.08e-15
Mbnl1	Mouse	Embryo	rep_5	33188776	5.51e-08
Mbnl1	Mouse	Embryo	rep_7	33188776	4.51e-06
Mbnl1	Mouse	Embryo	rep_12	33188776	4.84e-15
Mbnl1	Mouse	Embryo	rep_13	33188776	4.49e-15
Mbnl1	Mouse	Embryo	rep_15	33188776	2.44e-08
Mbnl1	Mouse	Kidney	rep_1	34853151	1.45e-11
Mbnl1	Mouse	Kidney	rep_5	34853151	1.95e-07
Mbnl1	Mouse	Brain	rep_1	33469025	1.30e-15
Mbnl1	Mouse	Brain	rep_1	35027729	6.92e-10
Mbnl1	Mouse	Brain	rep_2	35027729	2.83e-15
Mbnl1	Mouse	Brain	rep_3	35027729	1.32e-15
Mbnl1	Mouse	Brain	rep_5	35027729	1.53e-11
Mbnl1	Mouse	Intestine	rep_1	35149721	1.81e-14
Mbnl1	Mouse	Intestine	rep_2	35149721	5.49e-15
Mbnl1	Mouse	Intestine	rep_3	35149721	3.25e-15
Mbnl1	Mouse	Intestine	rep_4	35149721	2.30e-15
Mbnl1	Mouse	Testicle	rep_4	34731600	1.38e-14
Mbnl1	Mouse	Lymph	A1	0	3.30e-07
Mbnl1	Mouse	Lymph	B1	0	7.24e-10
Mbnl1	Mouse	Lung	rep_1	35290801	4.52e-15
Mbnl1	Mouse	Lung	rep_2	35290801	7.23e-15
Mbnl1	Mouse	Lung	rep_3	35290801	8.40e-15
Mbnl1	Mouse	Lung	rep_4	35290801	3.04e-15
Mbnl1	Mouse	Brain	OFB_polb_rep7	33083725	7.93e-03

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_1_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E
Brain_OFB_polb_rep7_H&E

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Spatial pattern pathway has Mbnl1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Mbnl1	GOBP_Mrna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.9e-06
Mbnl1	GOBP_Muscle_Structure_Development	Mouse	Spinal cord	CN94_E1	7.5e-07
Mbnl1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.8e-06
Mbnl1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Spinal cord	L7bCN01_D2	2.0e-06
Mbnl1	GOBP_Mrna_Processing	Mouse	Spinal cord	L7bCN02_E1	5.5e-06
Mbnl1	GOBP_Appendage_Development	Mouse	Spinal cord	L7CN45_C1	2.2e-06
Mbnl1	GOBP_Appendage_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	9.0e-08
Mbnl1	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Mbnl1	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Spinal cord	L7CN45_C1	3.9e-07
Mbnl1	GOBP_Embryonic_Appendage_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	6.5e-06
Mbnl1	GOBP_Embryonic_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Mbnl1	GOBP_Regulation_Of_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Spinal cord	L7CN45_C1	7.2e-06
Mbnl1	GOBP_Regulation_Of_Mrna_Processing	Mouse	Spinal cord	L7CN45_C1	3.9e-07
Mbnl1	GOBP_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Mouse	Spinal cord	L7CN45_C1	8.6e-06
Mbnl1	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Mbnl1	GOBP_Rna_Splicing	Mouse	Spinal cord	L7CN45_C1	3.7e-08
Mbnl1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Spinal cord	L7CN45_C1	1.8e-09
Mbnl1	GOBP_Regulation_Of_Rna_Splicing	Mouse	Spinal cord	L7CN47_C1	7.2e-06
Mbnl1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Brain	rep_1	1.8e-13
Mbnl1	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	rep_1	1.0e-08
Mbnl1	GOBP_In_Utero_Embryonic_Development	Mouse	Brain	rep_1	1.0e-19
Mbnl1	GOBP_Regulation_Of_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Brain	rep_1	1.5e-20
Mbnl1	GOBP_Appendage_Development	Mouse	Brain	rep_3	9.3e-152
Mbnl1	GOBP_Appendage_Morphogenesis	Mouse	Brain	rep_3	1.8e-121
Mbnl1	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
Mbnl1	GOBP_Embryonic_Appendage_Morphogenesis	Mouse	Brain	rep_3	1.2e-95
Mbnl1	GOBP_Embryonic_Morphogenesis	Mouse	Brain	rep_3	5.0e-165
Mbnl1	GOBP_Mrna_Metabolic_Process	Mouse	Brain	rep_3	3.9e-221
Mbnl1	GOBP_Mrna_Processing	Mouse	Brain	rep_3	4.7e-219
Mbnl1	GOBP_Muscle_Structure_Development	Mouse	Brain	rep_3	3.3e-77
Mbnl1	GOBP_Myoblast_Differentiation	Mouse	Brain	rep_3	4.8e-60
Mbnl1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Brain	rep_3	9.2e-182
Mbnl1	GOBP_Regulation_Of_Mrna_Processing	Mouse	Brain	rep_3	4.6e-195
Mbnl1	GOBP_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Mouse	Brain	rep_3	4.4e-174
Mbnl1	GOBP_Regulation_Of_Rna_Splicing	Mouse	Brain	rep_3	6.3e-171
Mbnl1	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Mbnl1	GOBP_Rna_Splicing	Mouse	Brain	rep_3	2.2e-224
Mbnl1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	rep_3	1.8e-234
Mbnl1	GOBP_Appendage_Development	Mouse	Embryo	rep_4	2.9e-07
Mbnl1	GOBP_Embryonic_Appendage_Morphogenesis	Mouse	Embryo	rep_14	2.4e-19
Mbnl1	GOBP_Myoblast_Differentiation	Mouse	Embryo	rep_14	5.0e-09
Mbnl1	GOBP_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Mouse	Embryo	rep_14	2.7e-08
Mbnl1	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Mbnl1	GOBP_Mrna_Metabolic_Process	Mouse	Embryo	rep_1	5.8e-21
Mbnl1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Embryo	rep_1	5.8e-21
Mbnl1	GOBP_Appendage_Development	Mouse	Embryo	rep_2	7.3e-30
Mbnl1	GOBP_Appendage_Morphogenesis	Mouse	Embryo	rep_2	7.3e-30
Mbnl1	GOBP_Embryonic_Appendage_Morphogenesis	Mouse	Embryo	rep_2	2.3e-43
Mbnl1	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Mbnl1	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
Mbnl1	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Embryo	rep_3	0.0e+00
Mbnl1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Kidney	rep_2	1.8e-64
Mbnl1	GOBP_Appendage_Development	Mouse	Kidney	rep_2	7.9e-84
Mbnl1	GOBP_Appendage_Morphogenesis	Mouse	Kidney	rep_2	6.0e-39
Mbnl1	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
Mbnl1	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Kidney	rep_2	9.8e-28
Mbnl1	GOBP_Embryonic_Appendage_Morphogenesis	Mouse	Kidney	rep_2	1.0e-52
Mbnl1	GOBP_Embryonic_Morphogenesis	Mouse	Kidney	rep_2	7.3e-66
Mbnl1	GOBP_In_Utero_Embryonic_Development	Mouse	Kidney	rep_2	7.1e-20
Mbnl1	GOBP_Mrna_Metabolic_Process	Mouse	Kidney	rep_2	3.1e-08
Mbnl1	GOBP_Mrna_Processing	Mouse	Kidney	rep_2	5.0e-53
Mbnl1	GOBP_Muscle_Structure_Development	Mouse	Kidney	rep_2	2.7e-36
Mbnl1	GOBP_Myoblast_Differentiation	Mouse	Kidney	rep_2	3.8e-48
Mbnl1	GOBP_Regulation_Of_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Kidney	rep_2	2.1e-76
Mbnl1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Kidney	rep_2	1.1e-20
Mbnl1	GOBP_Regulation_Of_Mrna_Processing	Mouse	Kidney	rep_2	2.1e-13
Mbnl1	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Mbnl1	GOBP_Rna_Splicing	Mouse	Kidney	rep_2	1.1e-33
Mbnl1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Kidney	rep_2	8.8e-36
Mbnl1	GOBP_In_Utero_Embryonic_Development	Mouse	Liver	CN16-D2	6.4e-07
Mbnl1	GOBP_Mrna_Metabolic_Process	Mouse	Liver	CN16-D2	5.2e-07
Mbnl1	GOBP_Mrna_Processing	Mouse	Liver	CN16-D2	4.8e-09
Mbnl1	GOBP_Regulation_Of_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Liver	CN16-D2	5.1e-07
Mbnl1	GOBP_Rna_Splicing	Mouse	Liver	CN16-D2	2.4e-07
Mbnl1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Liver	CN16-D2	2.0e-09
Mbnl1	GOBP_Appendage_Development	Mouse	Liver	CN16-E1	2.0e-11
Mbnl1	GOBP_Embryonic_Appendage_Morphogenesis	Mouse	Liver	CN65-C1	5.6e-08
Mbnl1	GOBP_Appendage_Development	Mouse	Liver	rep_15	1.7e-18
Mbnl1	GOBP_Embryonic_Appendage_Morphogenesis	Mouse	Liver	rep_15	1.5e-10
Mbnl1	GOBP_In_Utero_Embryonic_Development	Mouse	Liver	rep_16	7.6e-16
Mbnl1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Lymph	MS-1	2.8e-07
Mbnl1	GOBP_Appendage_Development	Mouse	Lymph	MS-1	2.7e-13
Mbnl1	GOBP_Appendage_Morphogenesis	Mouse	Lymph	MS-1	2.7e-10
Mbnl1	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
Mbnl1	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Lymph	MS-1	4.0e-11
Mbnl1	GOBP_Embryonic_Appendage_Morphogenesis	Mouse	Lymph	MS-1	4.4e-08
Mbnl1	GOBP_Embryonic_Morphogenesis	Mouse	Lymph	MS-1	5.6e-07
Mbnl1	GOBP_In_Utero_Embryonic_Development	Mouse	Lymph	MS-1	5.3e-13
Mbnl1	GOBP_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	3.2e-11
Mbnl1	GOBP_Muscle_Structure_Development	Mouse	Lymph	MS-1	3.8e-09
Mbnl1	GOBP_Myoblast_Differentiation	Mouse	Lymph	MS-1	1.3e-17
Mbnl1	GOBP_Regulation_Of_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Lymph	MS-1	4.3e-09
Mbnl1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	3.3e-08
Mbnl1	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Mbnl1	GOBP_Appendage_Morphogenesis	Mouse	Lung	rep_1	1.5e-07
Mbnl1	GOBP_Embryonic_Appendage_Morphogenesis	Mouse	Lung	rep_1	9.0e-11
Mbnl1	GOBP_Myoblast_Differentiation	Mouse	Lung	rep_1	3.3e-09
Mbnl1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Brain	HP_ad_rep7	6.7e-08
Mbnl1	GOBP_Appendage_Development	Mouse	Brain	HP_ad_rep7	5.7e-10
Mbnl1	GOBP_Appendage_Morphogenesis	Mouse	Brain	HP_ad_rep7	4.6e-07
Mbnl1	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	HP_ad_rep7	7.5e-07
Mbnl1	GOBP_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-09
Mbnl1	GOBP_Mrna_Processing	Mouse	Brain	HP_ad_rep7	2.3e-09
Mbnl1	GOBP_Regulation_Of_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Brain	HP_ad_rep7	9.3e-14
Mbnl1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	9.2e-08
Mbnl1	GOBP_Regulation_Of_Mrna_Processing	Mouse	Brain	HP_ad_rep7	2.2e-11
Mbnl1	GOBP_Regulation_Of_Mrna_Splicing_Via_Spliceosome	Mouse	Brain	HP_ad_rep7	2.3e-11
Mbnl1	GOBP_Regulation_Of_Rna_Splicing	Mouse	Brain	HP_ad_rep7	5.9e-11
Mbnl1	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Mbnl1	GOBP_Rna_Splicing	Mouse	Brain	HP_ad_rep7	5.3e-10
Mbnl1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	HP_ad_rep7	2.3e-11
Mbnl1	GOBP_Myoblast_Differentiation	Mouse	Brain	HP_adpolb_rep5	2.1e-07
Mbnl1	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
Mbnl1	GOBP_Embryonic_Morphogenesis	Mouse	Brain	HP_polb_rep9	3.7e-09
Mbnl1	GOBP_In_Utero_Embryonic_Development	Mouse	Brain	HP_polb_rep9	2.4e-10

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Mbnl1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Mbnl1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Mbnl1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Mbnl1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Mbnl1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Mbnl1	C3250443	MYOTONIC DYSTROPHY 1	2	UNIPROT
Mbnl1	C0027125	Myotonia	1	CTD_human
Mbnl1	C0036341	Schizophrenia	1	PSYGENET
Mbnl1	C0751358	Myotonic Phenomenon	1	CTD_human
Mbnl1	C0751359	Percussion Myotonia	1	CTD_human
Mbnl1	C2931456	Prostate cancer, familial	1	CTD_human
Mbnl1	C4722327	PROSTATE CANCER, HEREDITARY, 1	1	CTD_human