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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Astn2 (spascer ID:56079)

Gene summary for Astn2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Astn2
	Gene ID	56079
	Gene name	astrotactin 2
	Synonyms	1d8\|Astnl\|bM452J22.1
	Cytomap	4\|4 C1
	Type of gene	protein-coding
	Description	astrotactin-2bM243L4.1 (astrotactin 2)bM264P11.1 (astrotactin 2)bM383P24.1 (astrotactin 2)bM423P8.1 (astrotactin 2)bM468K2.1 (astrotactin 2)
	Modification date	20220424
	UniProtAcc	Q80Z10

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Astn2	GO:0001764	neuron migration	21873635	Process
Astn2	GO:0005768	endosome	21873635	Component
Astn2	GO:0007158	neuron cell-cell adhesion	21873635	Process
Astn2	GO:0016021	integral component of membrane	21873635	Component
Astn2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding	21873635	Function

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Spatial pattern events for Astn2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Astn2	Mouse	Brain	S1	34413515	2.79e-14
Astn2	Mouse	Brain	S2	34413515	2.85e-15
Astn2	Mouse	Brain	S6	34413515	1.94e-10
Astn2	Mouse	Embryo	1D	34210887	1.85e-08
Astn2	Mouse	Embryo	1E	34210887	3.33e-09
Astn2	Mouse	Embryo	1G	34210887	6.91e-14
Astn2	Mouse	Embryo	2G	34210887	3.68e-07
Astn2	Mouse	Embryo	2H	34210887	5.69e-09
Astn2	Mouse	Embryo	3G	34210887	2.85e-14
Astn2	Mouse	Embryo	4D	34210887	7.75e-15
Astn2	Mouse	Embryo	4E	34210887	4.53e-15
Astn2	Mouse	Brain	rep_1	35027729	8.60e-11
Astn2	Mouse	Brain	rep_2	35027729	2.13e-14
Astn2	Mouse	Brain	rep_3	35027729	4.57e-15
Astn2	Mouse	Brain	rep_4	35027729	9.80e-06
Astn2	Mouse	Brain	rep_5	35027729	3.53e-11

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Astn2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Astn2	GOBP_Regulation_Of_Cellular_Localization	Mouse	Spinal cord	CN94_E1	8.4e-06
Astn2	GOBP_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Spinal cord	CN94_E1	2.9e-06
Astn2	GOBP_Neuron_Cell_Cell_Adhesion	Mouse	Spinal cord	L7bCN02_E1	1.0e-06
Astn2	GOBP_Biological_Adhesion	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Astn2	GOBP_Cell_Cell_Adhesion	Mouse	Spinal cord	L7CN45_C1	6.8e-10
Astn2	GOBP_Cellular_Macromolecule_Localization	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Astn2	GOBP_Epithelium_Development	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Astn2	GOBP_Establishment_Of_Protein_Localization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Astn2	GOBP_Establishment_Of_Tissue_Polarity	Mouse	Spinal cord	L7CN45_C1	6.3e-09
Astn2	GOBP_Morphogenesis_Of_A_Polarized_Epithelium	Mouse	Spinal cord	L7CN45_C1	3.6e-06
Astn2	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Spinal cord	L7CN45_C1	8.3e-08
Astn2	GOBP_Neurogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Astn2	GOBP_Neuron_Migration	Mouse	Spinal cord	L7CN45_C1	5.7e-08
Astn2	GOBP_Tissue_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.3e-08
Astn2	GOBP_Cell_Migration	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Astn2	GOBP_Locomotion	Mouse	Spinal cord	L8CN11_D1	8.5e-06
Astn2	GOBP_Regulation_Of_Protein_Localization	Mouse	Spinal cord	L8CN14_E2	3.4e-12
Astn2	GOBP_Regulation_Of_Cellular_Localization	Mouse	Brain	rep_27	5.0e-06
Astn2	GOBP_Neuron_Cell_Cell_Adhesion	Mouse	Brain	rep_37	9.9e-06
Astn2	GOBP_Negative_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Brain	rep_71	1.4e-05
Astn2	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	rep_1	6.6e-07
Astn2	GOBP_Neurogenesis	Mouse	Brain	rep_1	6.4e-19
Astn2	GOBP_Neuron_Cell_Cell_Adhesion	Mouse	Brain	rep_1	2.1e-87
Astn2	GOBP_Neuron_Migration	Mouse	Brain	rep_1	1.6e-55
Astn2	GOBP_Protein_Localization_To_Cell_Surface	Mouse	Brain	rep_1	1.8e-13
Astn2	GOBP_Regulation_Of_Cellular_Localization	Mouse	Brain	rep_1	3.0e-15
Astn2	GOBP_Regulation_Of_Protein_Localization	Mouse	Brain	rep_1	2.2e-07
Astn2	GOBP_Biological_Adhesion	Mouse	Brain	rep_3	4.3e-106
Astn2	GOBP_Cell_Cell_Adhesion	Mouse	Brain	rep_3	5.2e-118
Astn2	GOBP_Cell_Migration	Mouse	Brain	rep_3	4.9e-108
Astn2	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	rep_3	1.6e-125
Astn2	GOBP_Epithelium_Development	Mouse	Brain	rep_3	8.3e-102
Astn2	GOBP_Establishment_Of_Tissue_Polarity	Mouse	Brain	rep_3	8.0e-91
Astn2	GOBP_Locomotion	Mouse	Brain	rep_3	5.4e-74
Astn2	GOBP_Morphogenesis_Of_A_Polarized_Epithelium	Mouse	Brain	rep_3	3.1e-46
Astn2	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Brain	rep_3	2.2e-135
Astn2	GOBP_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Brain	rep_3	7.0e-69
Astn2	GOBP_Tissue_Morphogenesis	Mouse	Brain	rep_3	4.8e-136
Astn2	GOBP_Establishment_Of_Tissue_Polarity	Mouse	Embryo	rep_14	5.6e-11
Astn2	GOBP_Morphogenesis_Of_A_Polarized_Epithelium	Mouse	Embryo	rep_14	2.1e-19
Astn2	GOBP_Negative_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Embryo	rep_14	1.0e-07
Astn2	GOBP_Neuron_Cell_Cell_Adhesion	Mouse	Embryo	rep_14	4.2e-101
Astn2	GOBP_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Embryo	rep_14	2.7e-09
Astn2	GOBP_Biological_Adhesion	Mouse	Embryo	rep_1	2.2e-19
Astn2	GOBP_Cell_Migration	Mouse	Embryo	rep_1	7.4e-36
Astn2	GOBP_Epithelium_Development	Mouse	Embryo	rep_1	1.7e-09
Astn2	GOBP_Locomotion	Mouse	Embryo	rep_1	1.7e-10
Astn2	GOBP_Neurogenesis	Mouse	Embryo	rep_1	8.2e-08
Astn2	GOBP_Cellular_Macromolecule_Localization	Mouse	Embryo	rep_2	5.5e-15
Astn2	GOBP_Establishment_Of_Tissue_Polarity	Mouse	Embryo	rep_3	0.0e+00
Astn2	GOBP_Morphogenesis_Of_A_Polarized_Epithelium	Mouse	Embryo	rep_3	3.7e-167
Astn2	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Embryo	rep_3	2.1e-14
Astn2	GOBP_Neuron_Migration	Mouse	Embryo	rep_3	1.8e-306
Astn2	GOBP_Cell_Migration	Mouse	Kidney	Nep	5.3e-07
Astn2	GOBP_Locomotion	Mouse	Kidney	Nep	5.3e-07
Astn2	GOBP_Neurogenesis	Mouse	Kidney	Nep	4.6e-22
Astn2	GOBP_Regulation_Of_Protein_Localization	Mouse	Kidney	Nep	1.1e-16
Astn2	GOBP_Biological_Adhesion	Mouse	Kidney	rep_2	1.3e-48
Astn2	GOBP_Cell_Cell_Adhesion	Mouse	Kidney	rep_2	1.1e-24
Astn2	GOBP_Cell_Migration	Mouse	Kidney	rep_2	4.7e-40
Astn2	GOBP_Cellular_Macromolecule_Localization	Mouse	Kidney	rep_2	3.5e-61
Astn2	GOBP_Epithelium_Development	Mouse	Kidney	rep_2	3.5e-92
Astn2	GOBP_Establishment_Of_Protein_Localization	Mouse	Kidney	rep_2	9.8e-86
Astn2	GOBP_Establishment_Of_Tissue_Polarity	Mouse	Kidney	rep_2	8.5e-64
Astn2	GOBP_Locomotion	Mouse	Kidney	rep_2	2.1e-43
Astn2	GOBP_Morphogenesis_Of_A_Polarized_Epithelium	Mouse	Kidney	rep_2	8.1e-21
Astn2	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Kidney	rep_2	8.3e-27
Astn2	GOBP_Negative_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Kidney	rep_2	1.2e-75
Astn2	GOBP_Neurogenesis	Mouse	Kidney	rep_2	2.4e-78
Astn2	GOBP_Neuron_Migration	Mouse	Kidney	rep_2	6.9e-61
Astn2	GOBP_Protein_Localization_To_Cell_Surface	Mouse	Kidney	rep_2	4.2e-10
Astn2	GOBP_Regulation_Of_Cellular_Localization	Mouse	Kidney	rep_2	2.8e-40
Astn2	GOBP_Regulation_Of_Protein_Localization	Mouse	Kidney	rep_2	1.5e-38
Astn2	GOBP_Tissue_Morphogenesis	Mouse	Kidney	rep_2	2.3e-21
Astn2	GOBP_Negative_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Liver	CN16-D2	3.4e-07
Astn2	GOBP_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Liver	CN16-D2	4.3e-12
Astn2	GOBP_Morphogenesis_Of_A_Polarized_Epithelium	Mouse	Liver	rep_15	3.0e-17
Astn2	GOBP_Neuron_Cell_Cell_Adhesion	Mouse	Liver	rep_15	2.3e-29
Astn2	GOBP_Biological_Adhesion	Mouse	Liver	rep_16	2.1e-07
Astn2	GOBP_Cell_Cell_Adhesion	Mouse	Liver	rep_16	1.4e-11
Astn2	GOBP_Cell_Migration	Mouse	Liver	rep_26	1.6e-10
Astn2	GOBP_Locomotion	Mouse	Liver	rep_26	1.6e-10
Astn2	GOBP_Neuron_Cell_Cell_Adhesion	Mouse	Intestine	rep_3	2.6e-33
Astn2	GOBP_Biological_Adhesion	Mouse	Lymph	MS-1	8.0e-14
Astn2	GOBP_Cell_Cell_Adhesion	Mouse	Lymph	MS-1	1.9e-13
Astn2	GOBP_Cell_Migration	Mouse	Lymph	MS-1	5.7e-13
Astn2	GOBP_Cellular_Macromolecule_Localization	Mouse	Lymph	MS-1	1.1e-11
Astn2	GOBP_Epithelium_Development	Mouse	Lymph	MS-1	8.5e-09
Astn2	GOBP_Establishment_Of_Protein_Localization	Mouse	Lymph	MS-1	2.5e-11
Astn2	GOBP_Establishment_Of_Tissue_Polarity	Mouse	Lymph	MS-1	1.5e-11
Astn2	GOBP_Locomotion	Mouse	Lymph	MS-1	1.2e-12
Astn2	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Lymph	MS-1	4.1e-10
Astn2	GOBP_Negative_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Lymph	MS-1	3.3e-27
Astn2	GOBP_Neurogenesis	Mouse	Lymph	MS-1	4.1e-08
Astn2	GOBP_Neuron_Migration	Mouse	Lymph	MS-1	1.7e-08
Astn2	GOBP_Protein_Localization_To_Cell_Surface	Mouse	Lymph	MS-1	5.4e-13
Astn2	GOBP_Regulation_Of_Cellular_Localization	Mouse	Lymph	MS-1	1.5e-07
Astn2	GOBP_Regulation_Of_Protein_Localization	Mouse	Lymph	MS-1	1.3e-07
Astn2	GOBP_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Lymph	MS-1	1.6e-07
Astn2	GOBP_Tissue_Morphogenesis	Mouse	Lymph	MS-1	1.4e-12
Astn2	GOBP_Biological_Adhesion	Mouse	Lung	rep_1	3.0e-22
Astn2	GOBP_Cell_Cell_Adhesion	Mouse	Lung	rep_1	2.9e-07
Astn2	GOBP_Neuron_Cell_Cell_Adhesion	Mouse	Brain	rep_4	3.8e-191
Astn2	GOBP_Neuron_Migration	Mouse	Brain	rep_4	1.6e-41
Astn2	GOBP_Neuron_Cell_Cell_Adhesion	Mouse	Brain	HP_ad_rep3	8.1e-09
Astn2	GOBP_Cell_Migration	Mouse	Brain	HP_ad_rep7	2.2e-07
Astn2	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	HP_ad_rep7	6.6e-10
Astn2	GOBP_Epithelium_Development	Mouse	Brain	HP_ad_rep7	2.8e-08
Astn2	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	HP_ad_rep7	8.7e-10
Astn2	GOBP_Locomotion	Mouse	Brain	HP_ad_rep7	3.8e-07
Astn2	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Brain	HP_ad_rep7	8.4e-09
Astn2	GOBP_Neurogenesis	Mouse	Brain	HP_ad_rep7	3.9e-07
Astn2	GOBP_Neuron_Migration	Mouse	Brain	HP_ad_rep7	5.0e-14
Astn2	GOBP_Regulation_Of_Cellular_Localization	Mouse	Brain	HP_ad_rep7	2.0e-07
Astn2	GOBP_Regulation_Of_Protein_Localization	Mouse	Brain	HP_ad_rep7	1.1e-09
Astn2	GOBP_Biological_Adhesion	Mouse	Brain	HP_polb_rep9	1.5e-07
Astn2	GOBP_Cell_Cell_Adhesion	Mouse	Brain	HP_polb_rep9	3.6e-11
Astn2	GOBP_Establishment_Of_Tissue_Polarity	Mouse	Brain	HP_polb_rep9	1.5e-14
Astn2	GOBP_Negative_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Brain	HP_polb_rep9	5.3e-07
Astn2	GOBP_Protein_Localization_To_Cell_Surface	Mouse	Brain	HP_polb_rep9	8.4e-13
Astn2	GOBP_Regulation_Of_Protein_Localization_To_Cell_Surface	Mouse	Brain	HP_polb_rep9	1.8e-11
Astn2	GOBP_Tissue_Morphogenesis	Mouse	Brain	HP_polb_rep9	1.2e-10

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Astn2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Astn2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Astn2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Astn2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Astn2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Astn2	C0036341	Schizophrenia	2	PSYGENET
Astn2	C0004352	Autistic Disorder	1	CTD_human
Astn2	C0005586	Bipolar Disorder	1	PSYGENET
Astn2	C0029410	Osteoarthritis of hip	1	CTD_human
Astn2	C0236733	Amphetamine-Related Disorders	1	CTD_human
Astn2	C0236804	Amphetamine Addiction	1	CTD_human
Astn2	C0236807	Amphetamine Abuse	1	CTD_human
Astn2	C0338480	Common Migraine	1	CTD_human