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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Iqgap2 (spascer ID:544963)

Gene summary for Iqgap2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Iqgap2
	Gene ID	544963
	Gene name	IQ motif containing GTPase activating protein 2
	Synonyms	4933417J23Rik\|A630053O10\|AI788777
	Cytomap	13 D1\|13 50.26 cM
	Type of gene	protein-coding
	Description	ras GTPase-activating-like protein IQGAP2
	Modification date	20220424
	UniProtAcc	Q3UQ44

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Iqgap2	GO:0005096	GTPase activator activity	21873635	Function
Iqgap2	GO:0005516	calmodulin binding	21873635	Function
Iqgap2	GO:0005737	cytoplasm	21873635	Component
Iqgap2	GO:0032956	regulation of actin cytoskeleton organization	21873635	Process
Iqgap2	GO:0051015	actin filament binding	21873635	Function

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Spatial pattern events for Iqgap2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Iqgap2	Mouse	Brain	S1	34413515	2.07e-15
Iqgap2	Mouse	Brain	S2	34413515	1.56e-15
Iqgap2	Mouse	Brain	S3	34413515	1.64e-15
Iqgap2	Mouse	Brain	S4	34413515	1.37e-15
Iqgap2	Mouse	Brain	S6	34413515	1.46e-15
Iqgap2	Mouse	Brain	S7	34413515	1.55e-15
Iqgap2	Mouse	Brain	17A	32637622	5.20e-08
Iqgap2	Mouse	Brain	19A	32637622	6.79e-08
Iqgap2	Mouse	Brain	19B	32637622	6.44e-09
Iqgap2	Mouse	Brain	21A	32637622	2.45e-07
Iqgap2	Mouse	Brain	21B	32637622	2.26e-14
Iqgap2	Mouse	Brain	22A	32637622	1.50e-14
Iqgap2	Mouse	Brain	22B	32637622	2.80e-14
Iqgap2	Mouse	Brain	23A	32637622	3.96e-10
Iqgap2	Mouse	Brain	23B	32637622	1.19e-07
Iqgap2	Mouse	Brain	24A	32637622	1.91e-07
Iqgap2	Mouse	Brain	24B	32637622	1.23e-10
Iqgap2	Mouse	Brain	26A	32637622	1.39e-11
Iqgap2	Mouse	Brain	26B	32637622	2.61e-09
Iqgap2	Mouse	Brain	27A	32637622	1.74e-14
Iqgap2	Mouse	Brain	27B	32637622	1.80e-14
Iqgap2	Mouse	Brain	28A	32637622	1.86e-14
Iqgap2	Mouse	Brain	28B	32637622	1.24e-14
Iqgap2	Mouse	Brain	29A	32637622	1.82e-14
Iqgap2	Mouse	Brain	29B	32637622	3.56e-14
Iqgap2	Mouse	Brain	30A	32637622	5.30e-07
Iqgap2	Mouse	Brain	31A	32637622	1.59e-14
Iqgap2	Mouse	Embryo	4E	34210887	7.66e-08
Iqgap2	Mouse	Embryo	rep_4	33188776	3.72e-12
Iqgap2	Mouse	Kidney	CLP	34003797	2.19e-15
Iqgap2	Mouse	Kidney	IRI	34003797	2.29e-15
Iqgap2	Mouse	Kidney	Sham	34003797	2.58e-15
Iqgap2	Mouse	Kidney	rep_1	34853151	6.28e-06
Iqgap2	Mouse	Kidney	rep_3	34853151	2.79e-07
Iqgap2	Mouse	Kidney	rep_4	34853151	1.26e-09
Iqgap2	Mouse	Kidney	rep_5	34853151	4.37e-13
Iqgap2	Mouse	Brain	rep_1	33469025	1.30e-15
Iqgap2	Mouse	Brain	rep_1	35027729	1.66e-15
Iqgap2	Mouse	Brain	rep_2	35027729	1.57e-15
Iqgap2	Mouse	Brain	rep_3	35027729	1.32e-15
Iqgap2	Mouse	Brain	rep_4	35027729	1.76e-15
Iqgap2	Mouse	Brain	rep_5	35027729	1.46e-15
Iqgap2	Mouse	Intestine	rep_1	35149721	6.08e-06
Iqgap2	Mouse	Intestine	rep_2	35149721	1.00e-14
Iqgap2	Mouse	Intestine	rep_3	35149721	3.25e-15
Iqgap2	Mouse	Intestine	rep_4	35149721	7.23e-15
Iqgap2	Mouse	Brain	B02_D1	32702314	2.21e-13
Iqgap2	Mouse	Brain	B02_E1	32702314	1.33e-14
Iqgap2	Mouse	Brain	B03_C2	32702314	9.29e-11
Iqgap2	Mouse	Brain	B03_D2	32702314	5.47e-07
Iqgap2	Mouse	Brain	B04_D1	32702314	2.29e-09
Iqgap2	Mouse	Brain	B06_E1	32702314	5.03e-06
Iqgap2	Mouse	Brain	N02_C1	32702314	4.03e-08
Iqgap2	Mouse	Brain	N02_D1	32702314	2.09e-13
Iqgap2	Mouse	Brain	N03_C2	32702314	3.29e-12
Iqgap2	Mouse	Brain	N03_D2	32702314	4.96e-13
Iqgap2	Mouse	Brain	N04_D1	32702314	2.72e-07
Iqgap2	Mouse	Brain	N05_C2	32702314	5.03e-11
Iqgap2	Mouse	Brain	N05_D2	32702314	1.93e-14
Iqgap2	Mouse	Lung	rep_3	35290801	2.20e-12

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_D1_H&E
Brain_B02_E1_H&E
Brain_B03_C2_H&E
Brain_B03_D2_H&E
Brain_B04_D1_H&E
Brain_B06_E1_H&E
Brain_N02_C1_H&E
Brain_N02_D1_H&E
Brain_N03_C2_H&E
Brain_N03_D2_H&E
Brain_N04_D1_H&E
Brain_N05_C2_H&E
Brain_N05_D2_H&E
Lung_rep_3_H&E

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Spatial pattern pathway has Iqgap2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Spinal cord	CN94_E1	4.2e-06
Iqgap2	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Iqgap2	GOBP_Thrombin_Activated_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN44_C1	5.6e-06
Iqgap2	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Iqgap2	GOBP_Arp2_3_Complex_Mediated_Actin_Nucleation	Mouse	Spinal cord	L7CN45_C1	8.1e-06
Iqgap2	GOBP_Cell_Activation	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Iqgap2	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Spinal cord	L7CN45_C1	9.9e-07
Iqgap2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	8.8e-08
Iqgap2	GOBP_Immune_Effector_Process	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Iqgap2	GOBP_Leukocyte_Mediated_Immunity	Mouse	Spinal cord	L7CN45_C1	2.4e-06
Iqgap2	GOBP_Myeloid_Leukocyte_Activation	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Spinal cord	L7CN45_C1	6.7e-06
Iqgap2	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Iqgap2	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Iqgap2	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Iqgap2	GOBP_Positive_Regulation_Of_Actin_Filament_Polymerization	Mouse	Spinal cord	L7CN45_C1	1.4e-08
Iqgap2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Spinal cord	L7CN45_C1	4.1e-06
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Spinal cord	L7CN45_C1	3.0e-06
Iqgap2	GOBP_Positive_Regulation_Of_Cytoskeleton_Organization	Mouse	Spinal cord	L7CN45_C1	4.5e-06
Iqgap2	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Spinal cord	L7CN45_C1	7.5e-06
Iqgap2	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	1.8e-08
Iqgap2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Iqgap2	GOBP_Regulation_Of_Anatomical_Structure_Size	Mouse	Spinal cord	L7CN45_C1	2.5e-06
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Size	Mouse	Spinal cord	L7CN45_C1	2.5e-06
Iqgap2	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	2.3e-07
Iqgap2	GOBP_Secretion	Mouse	Spinal cord	L7CN45_C1	8.1e-09
Iqgap2	GOBP_Actin_Filament_Based_Process	Mouse	Spinal cord	L7CN47_C1	3.4e-06
Iqgap2	GOBP_Exocytosis	Mouse	Spinal cord	L7CN47_C1	7.4e-07
Iqgap2	GOBP_Negative_Regulation_Of_Gtpase_Activity	Mouse	Spinal cord	L7CN47_D1	3.1e-06
Iqgap2	GOBP_Actin_Nucleation	Mouse	Spinal cord	L7CN60_D1	6.1e-06
Iqgap2	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Mouse	Spinal cord	L7CN97_E2	3.9e-07
Iqgap2	GOBP_Actin_Filament_Organization	Mouse	Spinal cord	L8CN17_E1	2.1e-07
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Spinal cord	L8CN17_E1	1.5e-07
Iqgap2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_27	8.0e-06
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_27	3.0e-05
Iqgap2	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_27	8.1e-06
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Brain	rep_27	1.1e-05
Iqgap2	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_27	4.2e-05
Iqgap2	GOBP_Secretion	Mouse	Brain	rep_27	8.9e-05
Iqgap2	GOBP_Cell_Activation	Mouse	Brain	rep_72	4.6e-06
Iqgap2	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Mouse	Brain	rep_75	1.0e-05
Iqgap2	GOBP_Actin_Filament_Based_Process	Mouse	Brain	rep_1	2.1e-24
Iqgap2	GOBP_Actin_Filament_Organization	Mouse	Brain	rep_1	4.6e-31
Iqgap2	GOBP_Actin_Nucleation	Mouse	Brain	rep_1	2.9e-32
Iqgap2	GOBP_Actin_Polymerization_Or_Depolymerization	Mouse	Brain	rep_1	2.4e-29
Iqgap2	GOBP_Arp2_3_Complex_Mediated_Actin_Nucleation	Mouse	Brain	rep_1	1.1e-20
Iqgap2	GOBP_Cell_Activation	Mouse	Brain	rep_1	1.8e-07
Iqgap2	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	rep_1	2.6e-13
Iqgap2	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Iqgap2	GOBP_Exocytosis	Mouse	Brain	rep_1	3.4e-73
Iqgap2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	4.5e-16
Iqgap2	GOBP_Immune_Effector_Process	Mouse	Brain	rep_1	1.5e-12
Iqgap2	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	rep_1	2.1e-07
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_1	1.3e-13
Iqgap2	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Brain	rep_1	1.0e-08
Iqgap2	GOBP_Positive_Regulation_Of_Actin_Filament_Polymerization	Mouse	Brain	rep_1	3.6e-31
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Brain	rep_1	3.6e-13
Iqgap2	GOBP_Positive_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	rep_1	4.4e-36
Iqgap2	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	2.1e-36
Iqgap2	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_1	1.0e-11
Iqgap2	GOBP_Positive_Regulation_Of_Organelle_Organization	Mouse	Brain	rep_1	2.2e-17
Iqgap2	GOBP_Positive_Regulation_Of_Protein_Polymerization	Mouse	Brain	rep_1	1.1e-29
Iqgap2	GOBP_Protein_Polymerization	Mouse	Brain	rep_1	3.4e-38
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Brain	rep_1	2.2e-33
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Length	Mouse	Brain	rep_1	2.6e-35
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Organization	Mouse	Brain	rep_1	4.7e-32
Iqgap2	GOBP_Regulation_Of_Anatomical_Structure_Size	Mouse	Brain	rep_1	1.0e-21
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Brain	rep_1	1.3e-27
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Size	Mouse	Brain	rep_1	6.5e-26
Iqgap2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-40
Iqgap2	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	5.6e-32
Iqgap2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	rep_1	7.9e-20
Iqgap2	GOBP_Regulation_Of_Protein_Containing_Complex_Assembly	Mouse	Brain	rep_1	1.2e-11
Iqgap2	GOBP_Regulation_Of_Protein_Polymerization	Mouse	Brain	rep_1	2.6e-38
Iqgap2	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Brain	rep_1	3.5e-07
Iqgap2	GOBP_Secretion	Mouse	Brain	rep_1	4.1e-45
Iqgap2	GOBP_Thrombin_Activated_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	8.9e-56
Iqgap2	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_3	5.2e-181
Iqgap2	GOBP_Negative_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_3	6.2e-33
Iqgap2	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_3	3.5e-163
Iqgap2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_3	8.5e-79
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Brain	rep_3	7.0e-65
Iqgap2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	rep_3	2.6e-94
Iqgap2	GOBP_Positive_Regulation_Of_Protein_Containing_Complex_Assembly	Mouse	Brain	rep_3	5.8e-122
Iqgap2	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_3	1.4e-120
Iqgap2	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	rep_3	6.7e-78
Iqgap2	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	3.3e-32
Iqgap2	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Mouse	Brain	rep_5	2.4e-61
Iqgap2	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Brain	rep_7	1.8e-32
Iqgap2	GOBP_Actin_Polymerization_Or_Depolymerization	Mouse	Embryo	rep_6	1.9e-07
Iqgap2	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Embryo	rep_6	1.4e-16
Iqgap2	GOBP_Negative_Regulation_Of_Gtpase_Activity	Mouse	Embryo	rep_6	3.6e-14
Iqgap2	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Mouse	Embryo	rep_6	1.6e-07
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Embryo	rep_6	4.1e-07
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Organization	Mouse	Embryo	rep_6	3.9e-14
Iqgap2	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Embryo	rep_14	8.6e-16
Iqgap2	GOBP_Actin_Nucleation	Mouse	Embryo	rep_14	1.3e-09
Iqgap2	GOBP_Arp2_3_Complex_Mediated_Actin_Nucleation	Mouse	Embryo	rep_14	5.8e-07
Iqgap2	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_14	3.3e-15
Iqgap2	GOBP_Leukocyte_Mediated_Immunity	Mouse	Embryo	rep_14	3.8e-12
Iqgap2	GOBP_Myeloid_Leukocyte_Activation	Mouse	Embryo	rep_14	2.9e-28
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Embryo	rep_14	1.7e-32
Iqgap2	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_14	4.4e-26
Iqgap2	GOBP_Positive_Regulation_Of_Actin_Filament_Polymerization	Mouse	Embryo	rep_14	3.3e-41
Iqgap2	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_14	8.5e-07
Iqgap2	GOBP_Thrombin_Activated_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	2.6e-29
Iqgap2	GOBP_Actin_Polymerization_Or_Depolymerization	Mouse	Embryo	rep_1	2.7e-93
Iqgap2	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Embryo	rep_1	2.5e-32
Iqgap2	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_1	4.6e-17
Iqgap2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Embryo	rep_1	2.2e-98
Iqgap2	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_1	1.6e-15
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Length	Mouse	Embryo	rep_1	2.7e-93
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Organization	Mouse	Embryo	rep_1	7.3e-294
Iqgap2	GOBP_Regulation_Of_Anatomical_Structure_Size	Mouse	Embryo	rep_1	1.2e-62
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Size	Mouse	Embryo	rep_1	2.9e-20
Iqgap2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Embryo	rep_1	2.6e-63
Iqgap2	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Embryo	rep_1	1.3e-102
Iqgap2	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Embryo	rep_2	3.4e-34
Iqgap2	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_2	1.7e-23
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Embryo	rep_2	2.3e-14
Iqgap2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Embryo	rep_3	0.0e+00
Iqgap2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Embryo	rep_3	1.3e-27
Iqgap2	GOBP_Supramolecular_Fiber_Organization	Mouse	Embryo	rep_3	0.0e+00
Iqgap2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	Nep	4.2e-26
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Kidney	Nep	4.2e-26
Iqgap2	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Kidney	Nep	8.3e-23
Iqgap2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	Nep	1.8e-46
Iqgap2	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.4e-48
Iqgap2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	Nep	1.8e-46
Iqgap2	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.3e-36
Iqgap2	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Kidney	rep_2	2.1e-101
Iqgap2	GOBP_Actin_Filament_Based_Process	Mouse	Kidney	rep_2	2.6e-107
Iqgap2	GOBP_Actin_Filament_Organization	Mouse	Kidney	rep_2	4.0e-81
Iqgap2	GOBP_Actin_Nucleation	Mouse	Kidney	rep_2	4.3e-117
Iqgap2	GOBP_Actin_Polymerization_Or_Depolymerization	Mouse	Kidney	rep_2	8.6e-53
Iqgap2	GOBP_Arp2_3_Complex_Mediated_Actin_Nucleation	Mouse	Kidney	rep_2	1.1e-102
Iqgap2	GOBP_Cell_Activation	Mouse	Kidney	rep_2	5.1e-83
Iqgap2	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Kidney	rep_2	4.3e-101
Iqgap2	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Iqgap2	GOBP_Exocytosis	Mouse	Kidney	rep_2	3.2e-107
Iqgap2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	3.0e-37
Iqgap2	GOBP_Immune_Effector_Process	Mouse	Kidney	rep_2	3.4e-107
Iqgap2	GOBP_Leukocyte_Mediated_Immunity	Mouse	Kidney	rep_2	2.7e-133
Iqgap2	GOBP_Myeloid_Leukocyte_Activation	Mouse	Kidney	rep_2	2.2e-110
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Kidney	rep_2	6.6e-105
Iqgap2	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Kidney	rep_2	5.2e-90
Iqgap2	GOBP_Negative_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	7.4e-61
Iqgap2	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	5.7e-63
Iqgap2	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Kidney	rep_2	2.5e-99
Iqgap2	GOBP_Positive_Regulation_Of_Actin_Filament_Polymerization	Mouse	Kidney	rep_2	3.5e-72
Iqgap2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	rep_2	2.1e-66
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Kidney	rep_2	2.9e-38
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Kidney	rep_2	2.4e-38
Iqgap2	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	2.1e-81
Iqgap2	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	3.6e-50
Iqgap2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	rep_2	2.2e-45
Iqgap2	GOBP_Positive_Regulation_Of_Organelle_Organization	Mouse	Kidney	rep_2	4.1e-12
Iqgap2	GOBP_Positive_Regulation_Of_Protein_Containing_Complex_Assembly	Mouse	Kidney	rep_2	5.6e-19
Iqgap2	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Mouse	Kidney	rep_2	2.0e-73
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Kidney	rep_2	2.1e-74
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Length	Mouse	Kidney	rep_2	1.9e-40
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Organization	Mouse	Kidney	rep_2	5.1e-82
Iqgap2	GOBP_Regulation_Of_Anatomical_Structure_Size	Mouse	Kidney	rep_2	1.3e-77
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Kidney	rep_2	8.3e-40
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Size	Mouse	Kidney	rep_2	1.0e-70
Iqgap2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.8e-22
Iqgap2	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	1.2e-71
Iqgap2	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	1.4e-60
Iqgap2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Kidney	rep_2	6.7e-77
Iqgap2	GOBP_Regulation_Of_Protein_Containing_Complex_Assembly	Mouse	Kidney	rep_2	1.8e-14
Iqgap2	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	9.1e-54
Iqgap2	GOBP_Secretion	Mouse	Kidney	rep_2	1.6e-23
Iqgap2	GOBP_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	9.5e-65
Iqgap2	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Liver	CN16-D2	1.9e-10
Iqgap2	GOBP_Thrombin_Activated_Receptor_Signaling_Pathway	Mouse	Liver	CN16-D2	2.6e-08
Iqgap2	GOBP_Negative_Regulation_Of_Gtpase_Activity	Mouse	Liver	CN65-C1	5.0e-07
Iqgap2	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Mouse	Liver	CN65-C1	2.8e-07
Iqgap2	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Liver	CN73-C1	9.9e-07
Iqgap2	GOBP_Myeloid_Leukocyte_Activation	Mouse	Liver	rep_15	2.4e-09
Iqgap2	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Liver	rep_16	1.6e-18
Iqgap2	GOBP_Exocytosis	Mouse	Liver	rep_16	8.5e-07
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Liver	rep_16	2.2e-20
Iqgap2	GOBP_Protein_Polymerization	Mouse	Liver	rep_16	3.0e-07
Iqgap2	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Lymph	MS-1	1.7e-07
Iqgap2	GOBP_Actin_Filament_Based_Process	Mouse	Lymph	MS-1	1.4e-10
Iqgap2	GOBP_Actin_Filament_Organization	Mouse	Lymph	MS-1	4.2e-11
Iqgap2	GOBP_Actin_Polymerization_Or_Depolymerization	Mouse	Lymph	MS-1	3.3e-09
Iqgap2	GOBP_Cell_Activation	Mouse	Lymph	MS-1	1.6e-18
Iqgap2	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Lymph	MS-1	9.7e-16
Iqgap2	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Iqgap2	GOBP_Exocytosis	Mouse	Lymph	MS-1	1.4e-14
Iqgap2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	1.8e-08
Iqgap2	GOBP_Immune_Effector_Process	Mouse	Lymph	MS-1	1.6e-18
Iqgap2	GOBP_Leukocyte_Mediated_Immunity	Mouse	Lymph	MS-1	5.6e-21
Iqgap2	GOBP_Myeloid_Leukocyte_Activation	Mouse	Lymph	MS-1	1.0e-18
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Lymph	MS-1	6.6e-07
Iqgap2	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Lymph	MS-1	2.2e-13
Iqgap2	GOBP_Negative_Regulation_Of_Gtpase_Activity	Mouse	Lymph	MS-1	6.1e-12
Iqgap2	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Lymph	MS-1	4.3e-09
Iqgap2	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Lymph	MS-1	6.9e-11
Iqgap2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Lymph	MS-1	2.2e-13
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Lymph	MS-1	3.6e-08
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Lymph	MS-1	1.8e-09
Iqgap2	GOBP_Positive_Regulation_Of_Cytoskeleton_Organization	Mouse	Lymph	MS-1	5.5e-09
Iqgap2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Lymph	MS-1	1.9e-12
Iqgap2	GOBP_Positive_Regulation_Of_Organelle_Organization	Mouse	Lymph	MS-1	2.8e-08
Iqgap2	GOBP_Positive_Regulation_Of_Protein_Containing_Complex_Assembly	Mouse	Lymph	MS-1	3.6e-08
Iqgap2	GOBP_Positive_Regulation_Of_Protein_Polymerization	Mouse	Lymph	MS-1	1.5e-11
Iqgap2	GOBP_Protein_Polymerization	Mouse	Lymph	MS-1	8.7e-08
Iqgap2	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Mouse	Lymph	MS-1	1.0e-06
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Based_Process	Mouse	Lymph	MS-1	1.7e-09
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Length	Mouse	Lymph	MS-1	5.2e-09
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Organization	Mouse	Lymph	MS-1	2.4e-09
Iqgap2	GOBP_Regulation_Of_Anatomical_Structure_Size	Mouse	Lymph	MS-1	1.1e-12
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Lymph	MS-1	2.2e-09
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Size	Mouse	Lymph	MS-1	1.1e-12
Iqgap2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Lymph	MS-1	8.4e-09
Iqgap2	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Lymph	MS-1	1.9e-08
Iqgap2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Lymph	MS-1	1.4e-10
Iqgap2	GOBP_Regulation_Of_Protein_Containing_Complex_Assembly	Mouse	Lymph	MS-1	2.3e-12
Iqgap2	GOBP_Regulation_Of_Protein_Polymerization	Mouse	Lymph	MS-1	5.2e-09
Iqgap2	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	4.3e-11
Iqgap2	GOBP_Secretion	Mouse	Lymph	MS-1	2.3e-12
Iqgap2	GOBP_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	1.5e-12
Iqgap2	GOBP_Thrombin_Activated_Receptor_Signaling_Pathway	Mouse	Lymph	MS-2	5.4e-08
Iqgap2	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Lung	rep_1	6.3e-10
Iqgap2	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Lung	rep_1	9.4e-15
Iqgap2	GOBP_Positive_Regulation_Of_Actin_Filament_Polymerization	Mouse	Lung	rep_1	5.0e-07
Iqgap2	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	rep_4	2.9e-33
Iqgap2	GOBP_Exocytosis	Mouse	Brain	rep_4	2.4e-43
Iqgap2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_4	1.7e-17
Iqgap2	GOBP_Immune_Effector_Process	Mouse	Brain	rep_4	7.2e-15
Iqgap2	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	6.4e-19
Iqgap2	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	rep_4	3.5e-20
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	3.7e-62
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Brain	rep_4	1.5e-12
Iqgap2	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_4	7.8e-12
Iqgap2	GOBP_Thrombin_Activated_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep2	6.9e-07
Iqgap2	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Brain	HP_ad_rep7	2.6e-08
Iqgap2	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Iqgap2	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	HP_ad_rep7	4.4e-14
Iqgap2	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Brain	HP_ad_rep7	4.0e-09
Iqgap2	GOBP_Negative_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_ad_rep7	9.8e-13
Iqgap2	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Brain	HP_ad_rep7	3.4e-10
Iqgap2	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	HP_ad_rep7	2.8e-07
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Brain	HP_ad_rep7	1.7e-11
Iqgap2	GOBP_Positive_Regulation_Of_Cellular_Component_Organization	Mouse	Brain	HP_ad_rep7	2.0e-07
Iqgap2	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_ad_rep7	4.8e-07
Iqgap2	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	HP_ad_rep7	2.8e-07
Iqgap2	GOBP_Positive_Regulation_Of_Organelle_Organization	Mouse	Brain	HP_ad_rep7	3.5e-08
Iqgap2	GOBP_Positive_Regulation_Of_Protein_Containing_Complex_Assembly	Mouse	Brain	HP_ad_rep7	9.6e-09
Iqgap2	GOBP_Positive_Regulation_Of_Protein_Polymerization	Mouse	Brain	HP_ad_rep7	2.7e-08
Iqgap2	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Mouse	Brain	HP_ad_rep7	6.5e-10
Iqgap2	GOBP_Regulation_Of_Organelle_Organization	Mouse	Brain	HP_ad_rep7	8.1e-07
Iqgap2	GOBP_Regulation_Of_Protein_Containing_Complex_Assembly	Mouse	Brain	HP_ad_rep7	1.6e-08
Iqgap2	GOBP_Secretion	Mouse	Brain	HP_ad_rep7	1.6e-08
Iqgap2	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	HP_ad_rep7	5.2e-07
Iqgap2	GOBP_Actin_Filament_Based_Process	Mouse	Brain	HP_polb_rep9	3.0e-07
Iqgap2	GOBP_Cell_Activation	Mouse	Brain	HP_polb_rep9	1.5e-08
Iqgap2	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	HP_polb_rep9	8.8e-09
Iqgap2	GOBP_Exocytosis	Mouse	Brain	HP_polb_rep9	2.3e-13
Iqgap2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	6.4e-16
Iqgap2	GOBP_Immune_Effector_Process	Mouse	Brain	HP_polb_rep9	1.0e-08
Iqgap2	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	HP_polb_rep9	2.8e-07
Iqgap2	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	HP_polb_rep9	2.6e-11
Iqgap2	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_polb_rep9	7.1e-13
Iqgap2	GOBP_Positive_Regulation_Of_Actin_Filament_Polymerization	Mouse	Brain	HP_polb_rep9	2.6e-08
Iqgap2	GOBP_Positive_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	HP_polb_rep9	5.5e-09
Iqgap2	GOBP_Protein_Polymerization	Mouse	Brain	HP_polb_rep9	5.9e-08
Iqgap2	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Mouse	Brain	HP_polb_rep9	1.0e-07
Iqgap2	GOBP_Regulation_Of_Actin_Filament_Length	Mouse	Brain	HP_polb_rep9	1.1e-07
Iqgap2	GOBP_Regulation_Of_Anatomical_Structure_Size	Mouse	Brain	HP_polb_rep9	9.1e-07
Iqgap2	GOBP_Regulation_Of_Cytoskeleton_Organization	Mouse	Brain	HP_polb_rep9	1.1e-07
Iqgap2	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_polb_rep9	4.2e-09
Iqgap2	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_polb_rep9	6.0e-09
Iqgap2	GOBP_Actin_Nucleation	Mouse	Brain	HP_wt_rep2	1.0e-13
Iqgap2	GOBP_Arp2_3_Complex_Mediated_Actin_Nucleation	Mouse	Brain	HP_wt_rep2	4.8e-11
Iqgap2	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_wt_rep2	2.1e-07

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Iqgap2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Iqgap2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Iqgap2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Iqgap2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Iqgap2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Iqgap2	C0006118	Brain Neoplasms	1	CTD_human
Iqgap2	C0153633	Malignant neoplasm of brain	1	CTD_human
Iqgap2	C0496899	Benign neoplasm of brain, unspecified	1	CTD_human
Iqgap2	C0750974	Brain Tumor, Primary	1	CTD_human
Iqgap2	C0750977	Recurrent Brain Neoplasm	1	CTD_human
Iqgap2	C0750979	Primary malignant neoplasm of brain	1	CTD_human
Iqgap2	C1527390	Neoplasms, Intracranial	1	CTD_human
Iqgap2	C2239176	Liver carcinoma	1	CTD_human