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Spatial pattern gene: Atxn10 (spascer ID:54138) |
Gene summary for Atxn10 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Atxn10 | Gene ID | 54138 |
| Gene name | ataxin 10 |
| Synonyms | AI325283|C77170|E46|Sca10|TEG-169|Tex169 |
| Cytomap | 15|15 E2 |
| Type of gene | protein-coding |
| Description | ataxin-10brain protein E46spinocerebellar ataxia type 10 protein homologtestis expressed gene 169 |
| Modification date | 20220424 |
| UniProtAcc | P28658 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Atxn10 | GO:0005829 | cytosol | 21873635 | Component |
| Atxn10 | GO:0031175 | neuron projection development | 21873635 | Process |
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Spatial pattern events for Atxn10 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Atxn10 | Mouse | Brain | S1 | 34413515 | 3.73e-15 |
| Atxn10 | Mouse | Brain | S2 | 34413515 | 1.56e-15 |
| Atxn10 | Mouse | Brain | S3 | 34413515 | 1.64e-15 |
| Atxn10 | Mouse | Brain | S4 | 34413515 | 1.37e-15 |
| Atxn10 | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Atxn10 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Atxn10 | Mouse | Brain | 09B | 32637622 | 4.24e-10 |
| Atxn10 | Mouse | Brain | 13B | 32637622 | 2.60e-08 |
| Atxn10 | Mouse | Brain | 19B | 32637622 | 6.11e-06 |
| Atxn10 | Mouse | Brain | 29A | 32637622 | 7.87e-09 |
| Atxn10 | Mouse | Brain | 29B | 32637622 | 2.01e-07 |
| Atxn10 | Mouse | Brain | rep_1 | 35141374 | 2.02e-15 |
| Atxn10 | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Atxn10 | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Atxn10 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Atxn10 | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Atxn10 | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Atxn10 | Mouse | Embryo | rep_3 | 33188776 | 5.03e-07 |
| Atxn10 | Mouse | Embryo | rep_4 | 33188776 | 8.29e-15 |
| Atxn10 | Mouse | Embryo | rep_5 | 33188776 | 5.68e-11 |
| Atxn10 | Mouse | Kidney | CLP | 34003797 | 3.97e-10 |
| Atxn10 | Mouse | Kidney | IRI | 34003797 | 7.37e-15 |
| Atxn10 | Mouse | Kidney | Sham | 34003797 | 4.36e-12 |
| Atxn10 | Mouse | Kidney | rep_1 | 34853151 | 7.20e-06 |
| Atxn10 | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Atxn10 | Mouse | Liver | rep_21 | 35021063 | 2.33e-11 |
| Atxn10 | Mouse | Brain | rep_1 | 35027729 | 1.66e-15 |
| Atxn10 | Mouse | Brain | rep_2 | 35027729 | 1.57e-15 |
| Atxn10 | Mouse | Brain | rep_3 | 35027729 | 1.32e-15 |
| Atxn10 | Mouse | Brain | rep_4 | 35027729 | 1.76e-15 |
| Atxn10 | Mouse | Brain | rep_5 | 35027729 | 1.46e-15 |
| Atxn10 | Mouse | Brain | B05_D2 | 32702314 | 1.51e-13 |
| Atxn10 | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Atxn10 | Mouse | Lymph | B1 | 0 | 1.11e-14 |
| Atxn10 | Mouse | Brain | rep_1 | 35210624 | 1.74e-15 |
| Atxn10 | Mouse | Brain | rep_2 | 35210624 | 1.74e-15 |
| Atxn10 | Mouse | Brain | rep_3 | 35210624 | 1.82e-15 |
| Atxn10 | Mouse | Brain | rep_5 | 35210624 | 2.07e-15 |
| Atxn10 | Mouse | Brain | rep_6 | 35210624 | 2.05e-15 |
| Atxn10 | Mouse | Brain | rep_7 | 35210624 | 1.87e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Brain_rep_1_H&E  | |
Liver_rep_21_H&E  | |
Brain_rep_1_H&E  |  |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_B05_D2_H&E  |  |
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Spatial pattern pathway has Atxn10 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Atxn10 | GOBP_Cell_Projection_Assembly | Mouse | Spinal cord | CN94_E1 | 3.2e-06 |
| Atxn10 | GOBP_Organelle_Assembly | Mouse | Spinal cord | CN94_E1 | 9.5e-06 |
| Atxn10 | GOBP_Cell_Projection_Organization | Mouse | Spinal cord | L7CN45_C1 | 1.2e-07 |
| Atxn10 | GOBP_Cilium_Organization | Mouse | Spinal cord | L7CN45_C1 | 5.6e-09 |
| Atxn10 | GOBP_Neurogenesis | Mouse | Spinal cord | L7CN45_C1 | 3.4e-09 |
| Atxn10 | GOBP_Neuron_Development | Mouse | Spinal cord | L7CN45_C1 | 5.6e-08 |
| Atxn10 | GOBP_Neuron_Differentiation | Mouse | Spinal cord | L7CN45_C1 | 3.4e-09 |
| Atxn10 | GOBP_Cilium_Organization | Mouse | Brain | rep_27 | 3.1e-06 |
| Atxn10 | GOBP_Cell_Projection_Assembly | Mouse | Brain | rep_1 | 8.3e-09 |
| Atxn10 | GOBP_Cell_Projection_Organization | Mouse | Brain | rep_1 | 2.6e-08 |
| Atxn10 | GOBP_Neurogenesis | Mouse | Brain | rep_1 | 6.4e-19 |
| Atxn10 | GOBP_Neuron_Development | Mouse | Brain | rep_1 | 3.8e-29 |
| Atxn10 | GOBP_Neuron_Differentiation | Mouse | Brain | rep_1 | 8.7e-25 |
| Atxn10 | GOBP_Cilium_Organization | Mouse | Brain | rep_3 | 3.3e-172 |
| Atxn10 | GOBP_Organelle_Assembly | Mouse | Brain | rep_3 | 2.0e-160 |
| Atxn10 | GOBP_Cilium_Organization | Mouse | Embryo | rep_1 | 1.8e-293 |
| Atxn10 | GOBP_Neurogenesis | Mouse | Embryo | rep_1 | 8.2e-08 |
| Atxn10 | GOBP_Neuron_Development | Mouse | Embryo | rep_2 | 4.8e-18 |
| Atxn10 | GOBP_Cell_Projection_Organization | Mouse | Embryo | rep_3 | 1.7e-72 |
| Atxn10 | GOBP_Neuron_Differentiation | Mouse | Embryo | rep_3 | 2.1e-193 |
| Atxn10 | GOBP_Organelle_Assembly | Mouse | Embryo | rep_6 | 4.1e-70 |
| Atxn10 | GOBP_Neurogenesis | Mouse | Kidney | Nep | 4.6e-22 |
| Atxn10 | GOBP_Neuron_Development | Mouse | Kidney | Nep | 8.3e-23 |
| Atxn10 | GOBP_Neuron_Differentiation | Mouse | Kidney | Nep | 8.3e-23 |
| Atxn10 | GOBP_Cell_Projection_Assembly | Mouse | Kidney | rep_2 | 3.6e-69 |
| Atxn10 | GOBP_Cell_Projection_Organization | Mouse | Kidney | rep_2 | 4.1e-48 |
| Atxn10 | GOBP_Cilium_Organization | Mouse | Kidney | rep_2 | 3.5e-79 |
| Atxn10 | GOBP_Neurogenesis | Mouse | Kidney | rep_2 | 2.4e-78 |
| Atxn10 | GOBP_Neuron_Development | Mouse | Kidney | rep_2 | 1.3e-42 |
| Atxn10 | GOBP_Neuron_Differentiation | Mouse | Kidney | rep_2 | 3.9e-32 |
| Atxn10 | GOBP_Organelle_Assembly | Mouse | Kidney | rep_2 | 2.8e-62 |
| Atxn10 | GOBP_Neuron_Differentiation | Mouse | Liver | CN16-D2 | 5.1e-07 |
| Atxn10 | GOBP_Cell_Projection_Organization | Mouse | Liver | rep_16 | 3.4e-07 |
| Atxn10 | GOBP_Cell_Projection_Assembly | Mouse | Lymph | MS-1 | 1.4e-09 |
| Atxn10 | GOBP_Cell_Projection_Organization | Mouse | Lymph | MS-1 | 1.5e-09 |
| Atxn10 | GOBP_Neurogenesis | Mouse | Lymph | MS-1 | 4.1e-08 |
| Atxn10 | GOBP_Organelle_Assembly | Mouse | Lymph | MS-1 | 5.5e-08 |
| Atxn10 | GOBP_Cell_Projection_Assembly | Mouse | Brain | HP_ad_rep7 | 1.0e-07 |
| Atxn10 | GOBP_Cell_Projection_Organization | Mouse | Brain | HP_ad_rep7 | 8.1e-09 |
| Atxn10 | GOBP_Cilium_Organization | Mouse | Brain | HP_ad_rep7 | 3.0e-08 |
| Atxn10 | GOBP_Neurogenesis | Mouse | Brain | HP_ad_rep7 | 3.9e-07 |
| Atxn10 | GOBP_Neuron_Development | Mouse | Brain | HP_ad_rep7 | 3.9e-07 |
| Atxn10 | GOBP_Neuron_Differentiation | Mouse | Brain | HP_ad_rep7 | 3.9e-07 |
| Atxn10 | GOBP_Organelle_Assembly | Mouse | Brain | HP_adpolb_rep1 | 1.8e-07 |
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Atxn10 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Atxn10 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Atxn10 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Atxn10 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Atxn10 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Atxn10 | C0687120 | Nephronophthisis | 1 | GENOMICS_ENGLAND |
| Atxn10 | C1963674 | Spinocerebellar Ataxia 10 | 1 | CTD_human;GENOMICS_ENGLAND;ORPHANET |
