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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Irf3 (spascer ID:54131)

Gene summary for Irf3

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Irf3
	Gene ID	54131
	Gene name	interferon regulatory factor 3
	Synonyms	C920001K05Rik\|IRF-3
	Cytomap	7\|7 B3
	Type of gene	protein-coding
	Description	interferon regulatory factor 3
	Modification date	20220510
	UniProtAcc	P70671

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Irf3	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	21873635	Function
Irf3	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	21873635	Function
Irf3	GO:0002376	immune system process	21873635	Process
Irf3	GO:0005634	nucleus	21873635	Component
Irf3	GO:0006357	regulation of transcription by RNA polymerase II	21873635	Process

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Spatial pattern events for Irf3

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Irf3	Mouse	Brain	S4	34413515	2.43e-15
Irf3	Mouse	Brain	S6	34413515	1.43e-07
Irf3	Mouse	Brain	rep_1	35141374	7.98e-08
Irf3	Mouse	Brain	rep_5	35141374	3.36e-07
Irf3	Mouse	Kidney	CLP	34003797	7.03e-06
Irf3	Mouse	Kidney	IRI	34003797	1.13e-08
Irf3	Mouse	Kidney	Sham	34003797	1.74e-06
Irf3	Mouse	Kidney	rep_1	34853151	4.13e-15
Irf3	Mouse	Kidney	rep_4	34853151	1.09e-11
Irf3	Mouse	Brain	rep_1	33469025	1.94e-13
Irf3	Mouse	Brain	rep_2	35027729	4.91e-07
Irf3	Mouse	Brain	rep_3	35027729	5.29e-09
Irf3	Mouse	Intestine	rep_4	35149721	3.90e-15
Irf3	Mouse	Lymph	A1	0	3.29e-15
Irf3	Mouse	Lymph	B1	0	8.19e-12
Irf3	Mouse	Brain	rep_1	35210624	6.02e-15
Irf3	Mouse	Brain	rep_2	35210624	5.02e-11
Irf3	Mouse	Brain	rep_3	35210624	2.61e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_5_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_4_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E

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Spatial pattern pathway has Irf3 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Irf3	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Spinal cord	CN94_E1	8.0e-06
Irf3	GOBP_Cellular_Response_To_Lipid	Mouse	Spinal cord	CN94_E1	1.8e-06
Irf3	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Spinal cord	CN94_E1	4.1e-07
Irf3	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	3.0e-06
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	1.1e-06
Irf3	GOBP_Inflammatory_Response	Mouse	Spinal cord	CN94_E1	8.2e-06
Irf3	GOBP_Necrotic_Cell_Death	Mouse	Spinal cord	CN94_E1	5.3e-09
Irf3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	1.6e-06
Irf3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	CN94_E1	6.2e-07
Irf3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	CN94_E1	2.2e-06
Irf3	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	CN94_E1	6.6e-06
Irf3	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Spinal cord	CN94_E1	2.1e-06
Irf3	GOBP_Programmed_Necrotic_Cell_Death	Mouse	Spinal cord	CN94_E1	3.2e-06
Irf3	GOBP_Regulation_Of_Defense_Response	Mouse	Spinal cord	CN94_E1	5.0e-06
Irf3	GOBP_Response_To_Nitrogen_Compound	Mouse	Spinal cord	CN94_E1	5.6e-06
Irf3	GOBP_Inflammatory_Cell_Apoptotic_Process	Mouse	Spinal cord	L7bCN01_D2	6.8e-06
Irf3	GOBP_Lipopolysaccharide_Mediated_Signaling_Pathway	Mouse	Spinal cord	L7bCN01_D2	3.5e-06
Irf3	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Spinal cord	L7bCN02_E1	6.8e-06
Irf3	GOBP_Myd88_Independent_Toll_Like_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7bCN02_E1	1.8e-08
Irf3	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Spinal cord	L7bCN02_E1	7.5e-06
Irf3	GOBP_Toll_Like_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7bCN02_E1	4.5e-07
Irf3	GOBP_Response_To_Type_I_Interferon	Mouse	Spinal cord	L7CN44_C1	6.9e-06
Irf3	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Irf3	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Irf3	GOBP_Cellular_Response_To_Virus	Mouse	Spinal cord	L7CN45_C1	2.6e-06
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway_In_Response_To_Virus	Mouse	Spinal cord	L7CN45_C1	6.1e-06
Irf3	GOBP_Immune_Effector_Process	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Irf3	GOBP_Interferon_Alpha_Production	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Irf3	GOBP_Interferon_Beta_Production	Mouse	Spinal cord	L7CN45_C1	1.5e-07
Irf3	GOBP_Leukocyte_Apoptotic_Process	Mouse	Spinal cord	L7CN45_C1	5.0e-08
Irf3	GOBP_Macrophage_Apoptotic_Process	Mouse	Spinal cord	L7CN45_C1	2.5e-06
Irf3	GOBP_Myeloid_Cell_Apoptotic_Process	Mouse	Spinal cord	L7CN45_C1	3.0e-06
Irf3	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Irf3	GOBP_Negative_Regulation_Of_Type_I_Interferon_Production	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Irf3	GOBP_Positive_Regulation_Of_Cytokine_Production	Mouse	Spinal cord	L7CN45_C1	7.2e-09
Irf3	GOBP_Positive_Regulation_Of_Defense_Response	Mouse	Spinal cord	L7CN45_C1	2.1e-07
Irf3	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Spinal cord	L7CN45_C1	9.1e-07
Irf3	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Spinal cord	L7CN45_C1	8.7e-09
Irf3	GOBP_Positive_Regulation_Of_Interferon_Alpha_Production	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Irf3	GOBP_Positive_Regulation_Of_Interferon_Beta_Production	Mouse	Spinal cord	L7CN45_C1	9.7e-08
Irf3	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Irf3	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Spinal cord	L7CN45_C1	6.3e-07
Irf3	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Mouse	Spinal cord	L7CN45_C1	2.9e-08
Irf3	GOBP_Positive_Regulation_Of_Signaling	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Irf3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	5.7e-09
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Production	Mouse	Spinal cord	L7CN45_C1	5.0e-08
Irf3	GOBP_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Irf3	GOBP_Regulation_Of_Inflammatory_Response	Mouse	Spinal cord	L7CN45_C1	3.3e-07
Irf3	GOBP_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Spinal cord	L7CN45_C1	2.8e-07
Irf3	GOBP_Regulation_Of_Response_To_External_Stimulus	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Irf3	GOBP_Regulation_Of_Response_To_Stress	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Irf3	GOBP_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	1.6e-06
Irf3	GOBP_Response_To_Cytokine	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Irf3	GOBP_Response_To_Dsrna	Mouse	Spinal cord	L7CN45_C1	1.7e-06
Irf3	GOBP_Response_To_Lipid	Mouse	Spinal cord	L7CN45_C1	2.3e-07
Irf3	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Spinal cord	L7CN45_C1	6.3e-07
Irf3	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Irf3	GOBP_Cellular_Response_To_Biotic_Stimulus	Mouse	Spinal cord	L7CN47_C1	3.9e-06
Irf3	GOBP_Cellular_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Spinal cord	L7CN47_C1	3.9e-06
Irf3	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN47_C1	3.1e-07
Irf3	GOBP_Positive_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Spinal cord	L7CN47_C1	2.6e-06
Irf3	GOBP_Regulation_Of_Innate_Immune_Response	Mouse	Spinal cord	L7CN47_C1	6.3e-08
Irf3	GOBP_Response_To_Bacterium	Mouse	Spinal cord	L7CN47_C1	8.3e-06
Irf3	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Spinal cord	L7CN47_C1	1.5e-06
Irf3	GOBP_Mda_5_Signaling_Pathway	Mouse	Spinal cord	L7CN47_D1	5.4e-07
Irf3	GOBP_Cytokine_Production	Mouse	Spinal cord	L7CN80_D2	4.5e-06
Irf3	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Spinal cord	L7CN97_E2	6.8e-06
Irf3	GOBP_Defense_Response_To_Other_Organism	Mouse	Spinal cord	L7CN97_E2	7.9e-07
Irf3	GOBP_Innate_Immune_Response	Mouse	Spinal cord	L7CN97_E2	2.7e-06
Irf3	GOBP_Defense_Response	Mouse	Spinal cord	L8CN11_C1	3.3e-17
Irf3	GOBP_Regulation_Of_Immune_Response	Mouse	Spinal cord	L8CN11_C1	4.7e-22
Irf3	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L8CN11_D1	5.6e-09
Irf3	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Spinal cord	L8CN17_E1	2.6e-06
Irf3	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Spinal cord	L8CN17_E1	7.6e-06
Irf3	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Spinal cord	L8CN17_E1	2.6e-06
Irf3	GOBP_Cellular_Response_To_Exogenous_Dsrna	Mouse	Brain	rep_19	1.9e-05
Irf3	GOBP_Cellular_Response_To_Biotic_Stimulus	Mouse	Brain	rep_27	3.6e-06
Irf3	GOBP_Cellular_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Brain	rep_27	8.5e-07
Irf3	GOBP_Mda_5_Signaling_Pathway	Mouse	Brain	rep_27	6.4e-06
Irf3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_27	7.2e-05
Irf3	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Brain	rep_27	4.7e-05
Irf3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_27	2.8e-05
Irf3	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	rep_27	8.3e-05
Irf3	GOBP_Regulation_Of_Cell_Death	Mouse	Brain	rep_27	6.3e-05
Irf3	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	rep_27	7.5e-06
Irf3	GOBP_Regulation_Of_Response_To_External_Stimulus	Mouse	Brain	rep_27	6.7e-05
Irf3	GOBP_Leukocyte_Apoptotic_Process	Mouse	Brain	rep_34	6.8e-05
Irf3	GOBP_Macrophage_Apoptotic_Process	Mouse	Brain	rep_37	5.4e-06
Irf3	GOBP_Myeloid_Cell_Apoptotic_Process	Mouse	Brain	rep_37	1.5e-05
Irf3	GOBP_Positive_Regulation_Of_Defense_Response	Mouse	Brain	rep_37	1.6e-05
Irf3	GOBP_Cellular_Response_To_Dsrna	Mouse	Brain	rep_41	5.0e-05
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Brain	rep_41	2.1e-09
Irf3	GOBP_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Brain	rep_41	1.1e-07
Irf3	GOBP_Response_To_Dsrna	Mouse	Brain	rep_41	1.0e-07
Irf3	GOBP_Inflammatory_Cell_Apoptotic_Process	Mouse	Brain	rep_47	4.8e-05
Irf3	GOBP_Cellular_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Brain	rep_1	4.2e-10
Irf3	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Brain	rep_1	1.5e-10
Irf3	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Brain	rep_1	1.3e-08
Irf3	GOBP_Immune_Effector_Process	Mouse	Brain	rep_1	1.5e-12
Irf3	GOBP_Inflammatory_Cell_Apoptotic_Process	Mouse	Brain	rep_1	2.6e-25
Irf3	GOBP_Interferon_Alpha_Production	Mouse	Brain	rep_1	9.0e-21
Irf3	GOBP_Interferon_Beta_Production	Mouse	Brain	rep_1	6.1e-28
Irf3	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	6.5e-10
Irf3	GOBP_Macrophage_Apoptotic_Process	Mouse	Brain	rep_1	4.0e-53
Irf3	GOBP_Myd88_Independent_Toll_Like_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	6.7e-13
Irf3	GOBP_Myeloid_Cell_Apoptotic_Process	Mouse	Brain	rep_1	2.3e-07
Irf3	GOBP_Necrotic_Cell_Death	Mouse	Brain	rep_1	5.3e-67
Irf3	GOBP_Negative_Regulation_Of_Cytokine_Production	Mouse	Brain	rep_1	1.0e-12
Irf3	GOBP_Negative_Regulation_Of_Type_I_Interferon_Production	Mouse	Brain	rep_1	2.8e-46
Irf3	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	2.7e-08
Irf3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_1	2.5e-12
Irf3	GOBP_Positive_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Brain	rep_1	1.0e-18
Irf3	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Mouse	Brain	rep_1	5.2e-18
Irf3	GOBP_Positive_Regulation_Of_Signaling	Mouse	Brain	rep_1	3.1e-07
Irf3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_1	1.6e-17
Irf3	GOBP_Response_To_Dsrna	Mouse	Brain	rep_1	1.9e-16
Irf3	GOBP_Response_To_Interferon_Gamma	Mouse	Brain	rep_1	1.9e-14
Irf3	GOBP_Toll_Like_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	5.4e-17
Irf3	GOBP_Type_I_Interferon_Production	Mouse	Brain	rep_1	1.5e-07
Irf3	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	rep_3	1.9e-146
Irf3	GOBP_Cellular_Response_To_Biotic_Stimulus	Mouse	Brain	rep_3	1.3e-32
Irf3	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	rep_3	5.0e-192
Irf3	GOBP_Cellular_Response_To_Dsrna	Mouse	Brain	rep_3	1.1e-137
Irf3	GOBP_Cellular_Response_To_Exogenous_Dsrna	Mouse	Brain	rep_3	1.0e-199
Irf3	GOBP_Cellular_Response_To_Lipid	Mouse	Brain	rep_3	4.6e-60
Irf3	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Brain	rep_3	1.3e-60
Irf3	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Brain	rep_3	8.2e-81
Irf3	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	rep_3	4.9e-10
Irf3	GOBP_Cytokine_Production	Mouse	Brain	rep_3	6.3e-65
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Brain	rep_3	3.8e-128
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway_In_Response_To_Virus	Mouse	Brain	rep_3	1.5e-115
Irf3	GOBP_Defense_Response	Mouse	Brain	rep_3	8.7e-77
Irf3	GOBP_Defense_Response_To_Other_Organism	Mouse	Brain	rep_3	6.0e-105
Irf3	GOBP_Inflammatory_Response	Mouse	Brain	rep_3	4.1e-53
Irf3	GOBP_Innate_Immune_Response	Mouse	Brain	rep_3	7.5e-97
Irf3	GOBP_Interferon_Gamma_Mediated_Signaling_Pathway	Mouse	Brain	rep_3	1.7e-145
Irf3	GOBP_Leukocyte_Apoptotic_Process	Mouse	Brain	rep_3	1.8e-181
Irf3	GOBP_Lipopolysaccharide_Mediated_Signaling_Pathway	Mouse	Brain	rep_3	2.0e-24
Irf3	GOBP_Mda_5_Signaling_Pathway	Mouse	Brain	rep_3	3.4e-98
Irf3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_3	1.4e-196
Irf3	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Brain	rep_3	1.1e-139
Irf3	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	rep_3	2.0e-111
Irf3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_3	9.4e-206
Irf3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_3	7.5e-168
Irf3	GOBP_Positive_Regulation_Of_Cytokine_Production	Mouse	Brain	rep_3	7.5e-78
Irf3	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Brain	rep_3	3.1e-102
Irf3	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Brain	rep_3	9.2e-94
Irf3	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Brain	rep_3	7.6e-125
Irf3	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.9e-97
Irf3	GOBP_Positive_Regulation_Of_Interferon_Alpha_Production	Mouse	Brain	rep_3	1.3e-117
Irf3	GOBP_Positive_Regulation_Of_Interferon_Beta_Production	Mouse	Brain	rep_3	1.8e-180
Irf3	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	3.3e-214
Irf3	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	rep_3	3.5e-105
Irf3	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Brain	rep_3	8.5e-178
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Brain	rep_3	6.2e-152
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Production	Mouse	Brain	rep_3	5.5e-105
Irf3	GOBP_Programmed_Necrotic_Cell_Death	Mouse	Brain	rep_3	1.5e-85
Irf3	GOBP_Regulation_Of_Cell_Death	Mouse	Brain	rep_3	7.6e-107
Irf3	GOBP_Regulation_Of_Defense_Response	Mouse	Brain	rep_3	5.3e-52
Irf3	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	rep_3	1.1e-86
Irf3	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.4e-111
Irf3	GOBP_Regulation_Of_Inflammatory_Response	Mouse	Brain	rep_3	2.2e-40
Irf3	GOBP_Regulation_Of_Innate_Immune_Response	Mouse	Brain	rep_3	2.2e-131
Irf3	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	1.3e-132
Irf3	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Brain	rep_3	9.3e-133
Irf3	GOBP_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Brain	rep_3	1.6e-104
Irf3	GOBP_Regulation_Of_Response_To_External_Stimulus	Mouse	Brain	rep_3	1.2e-94
Irf3	GOBP_Regulation_Of_Response_To_Stress	Mouse	Brain	rep_3	6.3e-95
Irf3	GOBP_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Brain	rep_3	4.3e-169
Irf3	GOBP_Response_To_Bacterium	Mouse	Brain	rep_3	3.1e-78
Irf3	GOBP_Response_To_Cytokine	Mouse	Brain	rep_3	1.2e-08
Irf3	GOBP_Response_To_Lipid	Mouse	Brain	rep_3	7.9e-86
Irf3	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	rep_3	2.5e-82
Irf3	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Brain	rep_3	3.4e-98
Irf3	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Brain	rep_3	6.3e-92
Irf3	GOBP_Response_To_Type_I_Interferon	Mouse	Brain	rep_3	3.1e-105
Irf3	GOBP_Response_To_Virus	Mouse	Brain	rep_3	2.3e-69
Irf3	GOBP_Interferon_Alpha_Production	Mouse	Embryo	rep_6	1.7e-08
Irf3	GOBP_Interferon_Beta_Production	Mouse	Embryo	rep_6	4.6e-12
Irf3	GOBP_Mda_5_Signaling_Pathway	Mouse	Embryo	rep_6	1.0e-12
Irf3	GOBP_Positive_Regulation_Of_Interferon_Alpha_Production	Mouse	Embryo	rep_6	1.2e-10
Irf3	GOBP_Toll_Like_Receptor_Signaling_Pathway	Mouse	Embryo	rep_6	1.2e-07
Irf3	GOBP_Cellular_Response_To_Dsrna	Mouse	Embryo	rep_14	6.6e-51
Irf3	GOBP_Cellular_Response_To_Exogenous_Dsrna	Mouse	Embryo	rep_14	1.0e-58
Irf3	GOBP_Cellular_Response_To_Virus	Mouse	Embryo	rep_14	2.2e-34
Irf3	GOBP_Cytokine_Production	Mouse	Embryo	rep_14	1.9e-09
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	8.6e-45
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway_In_Response_To_Virus	Mouse	Embryo	rep_14	7.9e-34
Irf3	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Embryo	rep_14	6.2e-28
Irf3	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_14	3.3e-15
Irf3	GOBP_Inflammatory_Cell_Apoptotic_Process	Mouse	Embryo	rep_14	2.6e-42
Irf3	GOBP_Interferon_Gamma_Mediated_Signaling_Pathway	Mouse	Embryo	rep_14	2.5e-13
Irf3	GOBP_Leukocyte_Apoptotic_Process	Mouse	Embryo	rep_14	7.7e-41
Irf3	GOBP_Lipopolysaccharide_Mediated_Signaling_Pathway	Mouse	Embryo	rep_14	1.2e-39
Irf3	GOBP_Macrophage_Apoptotic_Process	Mouse	Embryo	rep_14	2.3e-33
Irf3	GOBP_Myd88_Independent_Toll_Like_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	1.8e-20
Irf3	GOBP_Myeloid_Cell_Apoptotic_Process	Mouse	Embryo	rep_14	2.5e-43
Irf3	GOBP_Necrotic_Cell_Death	Mouse	Embryo	rep_14	1.1e-47
Irf3	GOBP_Negative_Regulation_Of_Cytokine_Production	Mouse	Embryo	rep_14	2.4e-09
Irf3	GOBP_Negative_Regulation_Of_Type_I_Interferon_Production	Mouse	Embryo	rep_14	2.3e-34
Irf3	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	5.2e-24
Irf3	GOBP_Positive_Regulation_Of_Cytokine_Production	Mouse	Embryo	rep_14	4.1e-16
Irf3	GOBP_Positive_Regulation_Of_Defense_Response	Mouse	Embryo	rep_14	3.1e-19
Irf3	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Embryo	rep_14	1.9e-23
Irf3	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Embryo	rep_14	9.6e-07
Irf3	GOBP_Positive_Regulation_Of_Interferon_Beta_Production	Mouse	Embryo	rep_14	6.6e-36
Irf3	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Embryo	rep_14	1.9e-19
Irf3	GOBP_Positive_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Embryo	rep_14	1.5e-56
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Embryo	rep_14	4.7e-51
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Production	Mouse	Embryo	rep_14	5.7e-46
Irf3	GOBP_Programmed_Necrotic_Cell_Death	Mouse	Embryo	rep_14	6.0e-26
Irf3	GOBP_Regulation_Of_Innate_Immune_Response	Mouse	Embryo	rep_14	2.6e-22
Irf3	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Embryo	rep_14	1.6e-07
Irf3	GOBP_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Embryo	rep_14	2.0e-29
Irf3	GOBP_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Embryo	rep_14	1.1e-32
Irf3	GOBP_Response_To_Dsrna	Mouse	Embryo	rep_14	3.7e-64
Irf3	GOBP_Response_To_Type_I_Interferon	Mouse	Embryo	rep_14	6.7e-26
Irf3	GOBP_Response_To_Virus	Mouse	Embryo	rep_14	1.4e-14
Irf3	GOBP_Type_I_Interferon_Production	Mouse	Embryo	rep_14	3.8e-21
Irf3	GOBP_Defense_Response	Mouse	Embryo	rep_1	5.2e-63
Irf3	GOBP_Inflammatory_Response	Mouse	Embryo	rep_1	1.1e-20
Irf3	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Embryo	rep_1	5.7e-69
Irf3	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Embryo	rep_1	9.4e-07
Irf3	GOBP_Positive_Regulation_Of_Defense_Response	Mouse	Embryo	rep_1	1.3e-231
Irf3	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	7.3e-23
Irf3	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Mouse	Embryo	rep_1	0.0e+00
Irf3	GOBP_Regulation_Of_Cell_Death	Mouse	Embryo	rep_1	8.4e-30
Irf3	GOBP_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	9.5e-143
Irf3	GOBP_Response_To_Cytokine	Mouse	Embryo	rep_1	8.2e-211
Irf3	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Embryo	rep_1	2.5e-19
Irf3	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Embryo	rep_2	7.4e-121
Irf3	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Embryo	rep_2	1.4e-08
Irf3	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_2	1.7e-23
Irf3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Embryo	rep_2	8.0e-13
Irf3	GOBP_Negative_Regulation_Of_Cytokine_Production	Mouse	Embryo	rep_2	1.0e-20
Irf3	GOBP_Positive_Regulation_Of_Signaling	Mouse	Embryo	rep_2	1.4e-07
Irf3	GOBP_Response_To_Bacterium	Mouse	Embryo	rep_2	7.8e-113
Irf3	GOBP_Response_To_Type_I_Interferon	Mouse	Embryo	rep_2	1.3e-21
Irf3	GOBP_Cellular_Response_To_Biotic_Stimulus	Mouse	Embryo	rep_3	1.2e-19
Irf3	GOBP_Cellular_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Embryo	rep_3	2.4e-14
Irf3	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Defense_Response_To_Other_Organism	Mouse	Embryo	rep_3	2.6e-164
Irf3	GOBP_Innate_Immune_Response	Mouse	Embryo	rep_3	2.0e-259
Irf3	GOBP_Leukocyte_Apoptotic_Process	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	1.5e-267
Irf3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Positive_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Embryo	rep_3	1.2e-42
Irf3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Regulation_Of_Innate_Immune_Response	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Embryo	rep_3	5.2e-46
Irf3	GOBP_Response_To_Interferon_Gamma	Mouse	Embryo	rep_3	2.5e-25
Irf3	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Embryo	rep_3	4.9e-23
Irf3	GOBP_Response_To_Nitrogen_Compound	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Response_To_Virus	Mouse	Embryo	rep_3	0.0e+00
Irf3	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Embryo	rep_5	1.8e-10
Irf3	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Embryo	rep_5	1.9e-15
Irf3	GOBP_Toll_Like_Receptor_Signaling_Pathway	Mouse	Embryo	rep_5	1.9e-15
Irf3	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Embryo	rep_6	1.5e-08
Irf3	GOBP_Regulation_Of_Response_To_External_Stimulus	Mouse	Embryo	rep_6	3.6e-24
Irf3	GOBP_Cytokine_Production	Mouse	Kidney	Nep	1.3e-32
Irf3	GOBP_Inflammatory_Response	Mouse	Kidney	Nep	6.5e-32
Irf3	GOBP_Positive_Regulation_Of_Cytokine_Production	Mouse	Kidney	Nep	5.6e-37
Irf3	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Kidney	Nep	4.9e-40
Irf3	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	Nep	5.3e-07
Irf3	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Kidney	Nep	1.8e-38
Irf3	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Mouse	Kidney	Nep	9.4e-31
Irf3	GOBP_Positive_Regulation_Of_Signaling	Mouse	Kidney	Nep	1.1e-39
Irf3	GOBP_Regulation_Of_Defense_Response	Mouse	Kidney	Nep	1.6e-30
Irf3	GOBP_Regulation_Of_Inflammatory_Response	Mouse	Kidney	Nep	1.6e-30
Irf3	GOBP_Regulation_Of_Response_To_External_Stimulus	Mouse	Kidney	Nep	1.1e-60
Irf3	GOBP_Regulation_Of_Response_To_Stress	Mouse	Kidney	Nep	1.1e-60
Irf3	GOBP_Response_To_Bacterium	Mouse	Kidney	Nep	2.6e-47
Irf3	GOBP_Response_To_Lipid	Mouse	Kidney	Nep	6.3e-23
Irf3	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	Nep	6.8e-28
Irf3	GOBP_Positive_Regulation_Of_Defense_Response	Mouse	Kidney	Sham	9.2e-21
Irf3	GOBP_Cellular_Response_To_Biotic_Stimulus	Mouse	Kidney	rep_2	1.1e-38
Irf3	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Kidney	rep_2	5.5e-146
Irf3	GOBP_Cellular_Response_To_Dsrna	Mouse	Kidney	rep_2	1.9e-26
Irf3	GOBP_Cellular_Response_To_Exogenous_Dsrna	Mouse	Kidney	rep_2	1.9e-25
Irf3	GOBP_Cellular_Response_To_Lipid	Mouse	Kidney	rep_2	2.2e-37
Irf3	GOBP_Cellular_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Kidney	rep_2	8.0e-58
Irf3	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Kidney	rep_2	5.2e-82
Irf3	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Kidney	rep_2	2.5e-50
Irf3	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	rep_2	4.5e-89
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway_In_Response_To_Virus	Mouse	Kidney	rep_2	5.1e-59
Irf3	GOBP_Defense_Response	Mouse	Kidney	rep_2	6.8e-127
Irf3	GOBP_Defense_Response_To_Other_Organism	Mouse	Kidney	rep_2	2.3e-129
Irf3	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Kidney	rep_2	1.5e-43
Irf3	GOBP_Immune_Effector_Process	Mouse	Kidney	rep_2	3.4e-107
Irf3	GOBP_Inflammatory_Cell_Apoptotic_Process	Mouse	Kidney	rep_2	8.0e-21
Irf3	GOBP_Inflammatory_Response	Mouse	Kidney	rep_2	8.2e-77
Irf3	GOBP_Innate_Immune_Response	Mouse	Kidney	rep_2	3.1e-117
Irf3	GOBP_Leukocyte_Apoptotic_Process	Mouse	Kidney	rep_2	3.2e-125
Irf3	GOBP_Lipopolysaccharide_Mediated_Signaling_Pathway	Mouse	Kidney	rep_2	1.1e-47
Irf3	GOBP_Macrophage_Apoptotic_Process	Mouse	Kidney	rep_2	3.2e-38
Irf3	GOBP_Mda_5_Signaling_Pathway	Mouse	Kidney	rep_2	3.4e-39
Irf3	GOBP_Myd88_Independent_Toll_Like_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	2.4e-21
Irf3	GOBP_Myeloid_Cell_Apoptotic_Process	Mouse	Kidney	rep_2	1.5e-54
Irf3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Kidney	rep_2	7.3e-42
Irf3	GOBP_Negative_Regulation_Of_Cytokine_Production	Mouse	Kidney	rep_2	2.0e-18
Irf3	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Kidney	rep_2	1.0e-19
Irf3	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Kidney	rep_2	2.6e-120
Irf3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	7.7e-30
Irf3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	2.2e-14
Irf3	GOBP_Negative_Regulation_Of_Type_I_Interferon_Production	Mouse	Kidney	rep_2	6.3e-42
Irf3	GOBP_Positive_Regulation_Of_Defense_Response	Mouse	Kidney	rep_2	2.0e-110
Irf3	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Kidney	rep_2	2.1e-103
Irf3	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Kidney	rep_2	2.0e-70
Irf3	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Kidney	rep_2	8.3e-94
Irf3	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	1.2e-85
Irf3	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Kidney	rep_2	2.7e-43
Irf3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	4.5e-10
Irf3	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Kidney	rep_2	1.4e-95
Irf3	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Mouse	Kidney	rep_2	1.5e-101
Irf3	GOBP_Positive_Regulation_Of_Signaling	Mouse	Kidney	rep_2	3.4e-17
Irf3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	8.3e-40
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Kidney	rep_2	2.9e-38
Irf3	GOBP_Programmed_Necrotic_Cell_Death	Mouse	Kidney	rep_2	2.1e-38
Irf3	GOBP_Regulation_Of_Defense_Response	Mouse	Kidney	rep_2	1.0e-93
Irf3	GOBP_Regulation_Of_Immune_Response	Mouse	Kidney	rep_2	1.3e-91
Irf3	GOBP_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	2.5e-84
Irf3	GOBP_Regulation_Of_Inflammatory_Response	Mouse	Kidney	rep_2	3.0e-78
Irf3	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	1.4e-17
Irf3	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Kidney	rep_2	7.0e-71
Irf3	GOBP_Regulation_Of_Response_To_External_Stimulus	Mouse	Kidney	rep_2	1.3e-111
Irf3	GOBP_Regulation_Of_Response_To_Stress	Mouse	Kidney	rep_2	2.8e-119
Irf3	GOBP_Response_To_Bacterium	Mouse	Kidney	rep_2	6.2e-146
Irf3	GOBP_Response_To_Cytokine	Mouse	Kidney	rep_2	3.1e-14
Irf3	GOBP_Response_To_Dsrna	Mouse	Kidney	rep_2	3.1e-41
Irf3	GOBP_Response_To_Interferon_Gamma	Mouse	Kidney	rep_2	1.3e-61
Irf3	GOBP_Response_To_Lipid	Mouse	Kidney	rep_2	1.1e-111
Irf3	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Kidney	rep_2	2.0e-33
Irf3	GOBP_Response_To_Nitrogen_Compound	Mouse	Kidney	rep_2	1.0e-56
Irf3	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Kidney	rep_2	1.3e-60
Irf3	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	rep_2	6.6e-112
Irf3	GOBP_Response_To_Virus	Mouse	Kidney	rep_2	1.1e-72
Irf3	GOBP_Toll_Like_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	1.0e-28
Irf3	GOBP_Positive_Regulation_Of_Interferon_Alpha_Production	Mouse	Liver	CN16-D2	2.4e-07
Irf3	GOBP_Positive_Regulation_Of_Interferon_Beta_Production	Mouse	Liver	CN16-D2	3.0e-09
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Production	Mouse	Liver	CN16-D2	2.3e-09
Irf3	GOBP_Inflammatory_Cell_Apoptotic_Process	Mouse	Liver	CN16-E1	7.0e-07
Irf3	GOBP_Interferon_Gamma_Mediated_Signaling_Pathway	Mouse	Liver	CN16-E1	7.3e-11
Irf3	GOBP_Cellular_Response_To_Exogenous_Dsrna	Mouse	Liver	CN65-C1	1.9e-07
Irf3	GOBP_Interferon_Beta_Production	Mouse	Liver	CN65-C1	7.3e-13
Irf3	GOBP_Mda_5_Signaling_Pathway	Mouse	Liver	CN65-C1	4.5e-07
Irf3	GOBP_Myeloid_Cell_Apoptotic_Process	Mouse	Liver	CN65-C1	3.9e-08
Irf3	GOBP_Type_I_Interferon_Production	Mouse	Liver	CN65-C1	5.0e-08
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway_In_Response_To_Virus	Mouse	Liver	rep_15	5.3e-08
Irf3	GOBP_Interferon_Gamma_Mediated_Signaling_Pathway	Mouse	Liver	rep_15	3.7e-07
Irf3	GOBP_Mda_5_Signaling_Pathway	Mouse	Liver	rep_15	4.5e-21
Irf3	GOBP_Necrotic_Cell_Death	Mouse	Liver	rep_15	3.0e-15
Irf3	GOBP_Cellular_Response_To_Dsrna	Mouse	Liver	rep_16	1.8e-10
Irf3	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Liver	rep_16	1.0e-14
Irf3	GOBP_Defense_Response	Mouse	Liver	rep_16	8.0e-16
Irf3	GOBP_Defense_Response_To_Other_Organism	Mouse	Liver	rep_16	1.8e-13
Irf3	GOBP_Inflammatory_Cell_Apoptotic_Process	Mouse	Liver	rep_16	1.5e-13
Irf3	GOBP_Inflammatory_Response	Mouse	Liver	rep_16	3.5e-14
Irf3	GOBP_Innate_Immune_Response	Mouse	Liver	rep_16	5.5e-09
Irf3	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	1.6e-08
Irf3	GOBP_Leukocyte_Apoptotic_Process	Mouse	Liver	rep_16	1.1e-10
Irf3	GOBP_Macrophage_Apoptotic_Process	Mouse	Liver	rep_16	2.4e-09
Irf3	GOBP_Myeloid_Cell_Apoptotic_Process	Mouse	Liver	rep_16	2.2e-10
Irf3	GOBP_Negative_Regulation_Of_Type_I_Interferon_Production	Mouse	Liver	rep_16	2.3e-17
Irf3	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	1.7e-07
Irf3	GOBP_Positive_Regulation_Of_Defense_Response	Mouse	Liver	rep_16	2.0e-25
Irf3	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Liver	rep_16	5.4e-07
Irf3	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Liver	rep_16	2.3e-11
Irf3	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Liver	rep_16	4.8e-29
Irf3	GOBP_Positive_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Liver	rep_16	1.5e-27
Irf3	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Mouse	Liver	rep_16	1.6e-17
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Production	Mouse	Liver	rep_16	1.9e-17
Irf3	GOBP_Programmed_Necrotic_Cell_Death	Mouse	Liver	rep_16	1.0e-11
Irf3	GOBP_Regulation_Of_Cell_Death	Mouse	Liver	rep_16	2.0e-13
Irf3	GOBP_Regulation_Of_Immune_Response	Mouse	Liver	rep_16	2.5e-16
Irf3	GOBP_Regulation_Of_Innate_Immune_Response	Mouse	Liver	rep_16	6.7e-14
Irf3	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Liver	rep_16	2.8e-11
Irf3	GOBP_Regulation_Of_Response_To_External_Stimulus	Mouse	Liver	rep_16	1.4e-07
Irf3	GOBP_Response_To_Cytokine	Mouse	Liver	rep_16	1.4e-13
Irf3	GOBP_Response_To_Dsrna	Mouse	Liver	rep_16	5.7e-16
Irf3	GOBP_Response_To_Interferon_Gamma	Mouse	Liver	rep_16	3.2e-16
Irf3	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Liver	rep_16	9.3e-09
Irf3	GOBP_Toll_Like_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	4.0e-07
Irf3	GOBP_Type_I_Interferon_Production	Mouse	Liver	rep_16	2.9e-18
Irf3	GOBP_Cellular_Response_To_Exogenous_Dsrna	Mouse	Brain	rep_1	3.1e-29
Irf3	GOBP_Inflammatory_Cell_Apoptotic_Process	Mouse	Brain	rep_1	8.7e-11
Irf3	GOBP_Macrophage_Apoptotic_Process	Mouse	Brain	rep_1	2.4e-07
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Brain	rep_1	4.7e-09
Irf3	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Lymph	MS-1	4.6e-18
Irf3	GOBP_Cellular_Response_To_Biotic_Stimulus	Mouse	Lymph	MS-1	1.1e-10
Irf3	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Lymph	MS-1	8.5e-13
Irf3	GOBP_Cellular_Response_To_Dsrna	Mouse	Lymph	MS-1	2.4e-08
Irf3	GOBP_Cellular_Response_To_Lipid	Mouse	Lymph	MS-1	8.6e-10
Irf3	GOBP_Cellular_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Lymph	MS-1	6.0e-19
Irf3	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Lymph	MS-1	7.5e-11
Irf3	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Lymph	MS-1	4.3e-09
Irf3	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Lymph	MS-1	7.5e-11
Irf3	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	6.7e-17
Irf3	GOBP_Cytokine_Production	Mouse	Lymph	MS-1	1.1e-16
Irf3	GOBP_Defense_Response	Mouse	Lymph	MS-1	8.6e-18
Irf3	GOBP_Defense_Response_To_Other_Organism	Mouse	Lymph	MS-1	6.7e-20
Irf3	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Lymph	MS-1	2.7e-15
Irf3	GOBP_Immune_Effector_Process	Mouse	Lymph	MS-1	1.6e-18
Irf3	GOBP_Inflammatory_Response	Mouse	Lymph	MS-1	1.2e-12
Irf3	GOBP_Innate_Immune_Response	Mouse	Lymph	MS-1	6.7e-20
Irf3	GOBP_Interferon_Beta_Production	Mouse	Lymph	MS-1	2.9e-08
Irf3	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	2.7e-11
Irf3	GOBP_Leukocyte_Apoptotic_Process	Mouse	Lymph	MS-1	6.9e-19
Irf3	GOBP_Lipopolysaccharide_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	5.0e-11
Irf3	GOBP_Macrophage_Apoptotic_Process	Mouse	Lymph	MS-1	1.2e-08
Irf3	GOBP_Myeloid_Cell_Apoptotic_Process	Mouse	Lymph	MS-1	2.0e-07
Irf3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-11
Irf3	GOBP_Negative_Regulation_Of_Cytokine_Production	Mouse	Lymph	MS-1	3.2e-16
Irf3	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Lymph	MS-1	6.3e-11
Irf3	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Lymph	MS-1	6.6e-16
Irf3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	1.8e-10
Irf3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	2.2e-09
Irf3	GOBP_Negative_Regulation_Of_Type_I_Interferon_Production	Mouse	Lymph	MS-1	1.4e-13
Irf3	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	2.1e-09
Irf3	GOBP_Positive_Regulation_Of_Cytokine_Production	Mouse	Lymph	MS-1	7.0e-13
Irf3	GOBP_Positive_Regulation_Of_Defense_Response	Mouse	Lymph	MS-1	1.2e-07
Irf3	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Lymph	MS-1	7.3e-12
Irf3	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Lymph	MS-1	3.7e-16
Irf3	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Lymph	MS-1	1.0e-21
Irf3	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	1.6e-18
Irf3	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	2.3e-12
Irf3	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Lymph	MS-1	1.4e-15
Irf3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Irf3	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Lymph	MS-1	8.3e-11
Irf3	GOBP_Positive_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Lymph	MS-1	6.3e-20
Irf3	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Mouse	Lymph	MS-1	7.5e-17
Irf3	GOBP_Positive_Regulation_Of_Signaling	Mouse	Lymph	MS-1	2.3e-12
Irf3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	1.7e-12
Irf3	GOBP_Programmed_Necrotic_Cell_Death	Mouse	Lymph	MS-1	2.3e-07
Irf3	GOBP_Regulation_Of_Cell_Death	Mouse	Lymph	MS-1	1.9e-12
Irf3	GOBP_Regulation_Of_Defense_Response	Mouse	Lymph	MS-1	1.4e-11
Irf3	GOBP_Regulation_Of_Immune_Response	Mouse	Lymph	MS-1	2.3e-21
Irf3	GOBP_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	2.2e-14
Irf3	GOBP_Regulation_Of_Inflammatory_Response	Mouse	Lymph	MS-1	1.4e-16
Irf3	GOBP_Regulation_Of_Innate_Immune_Response	Mouse	Lymph	MS-1	1.1e-08
Irf3	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.0e-14
Irf3	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Lymph	MS-1	1.6e-08
Irf3	GOBP_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Lymph	MS-1	7.0e-18
Irf3	GOBP_Regulation_Of_Response_To_External_Stimulus	Mouse	Lymph	MS-1	3.8e-16
Irf3	GOBP_Regulation_Of_Response_To_Stress	Mouse	Lymph	MS-1	1.1e-10
Irf3	GOBP_Response_To_Bacterium	Mouse	Lymph	MS-1	6.2e-20
Irf3	GOBP_Response_To_Cytokine	Mouse	Lymph	MS-1	5.7e-15
Irf3	GOBP_Response_To_Interferon_Gamma	Mouse	Lymph	MS-1	1.3e-12
Irf3	GOBP_Response_To_Lipid	Mouse	Lymph	MS-1	8.6e-10
Irf3	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Lymph	MS-1	1.1e-11
Irf3	GOBP_Response_To_Nitrogen_Compound	Mouse	Lymph	MS-1	1.8e-09
Irf3	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Lymph	MS-1	1.9e-09
Irf3	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Lymph	MS-1	1.8e-09
Irf3	GOBP_Response_To_Virus	Mouse	Lymph	MS-1	2.1e-12
Irf3	GOBP_Toll_Like_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	4.3e-07
Irf3	GOBP_Type_I_Interferon_Production	Mouse	Lymph	MS-1	2.0e-08
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Lymph	PBS	4.8e-07
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway_In_Response_To_Virus	Mouse	Lymph	PBS	1.5e-08
Irf3	GOBP_Positive_Regulation_Of_Interferon_Alpha_Production	Mouse	Lymph	PBS	7.4e-07
Irf3	GOBP_Positive_Regulation_Of_Interferon_Beta_Production	Mouse	Lymph	PBS	5.9e-09
Irf3	GOBP_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Lymph	PBS	4.6e-09
Irf3	GOBP_Cytokine_Production	Mouse	Lung	rep_1	1.7e-08
Irf3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lung	rep_1	7.5e-20
Irf3	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Lung	rep_1	4.5e-23
Irf3	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Lung	rep_1	1.3e-17
Irf3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lung	rep_1	5.8e-10
Irf3	GOBP_Regulation_Of_Response_To_Stress	Mouse	Lung	rep_1	3.3e-20
Irf3	GOBP_Response_To_Cytokine	Mouse	Lung	rep_1	1.2e-17
Irf3	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Lung	rep_1	5.0e-17
Irf3	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Lung	rep_1	1.2e-19
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway_In_Response_To_Virus	Mouse	Brain	rep_4	1.8e-15
Irf3	GOBP_Immune_Effector_Process	Mouse	Brain	rep_4	7.2e-15
Irf3	GOBP_Interferon_Alpha_Production	Mouse	Brain	rep_4	1.1e-17
Irf3	GOBP_Myd88_Independent_Toll_Like_Receptor_Signaling_Pathway	Mouse	Brain	rep_4	4.3e-40
Irf3	GOBP_Negative_Regulation_Of_Type_I_Interferon_Production	Mouse	Brain	rep_4	9.8e-73
Irf3	GOBP_Positive_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Brain	rep_4	1.0e-28
Irf3	GOBP_Type_I_Interferon_Production	Mouse	Brain	rep_4	6.8e-13
Irf3	GOBP_Interferon_Beta_Production	Mouse	Brain	rep_7	3.8e-09
Irf3	GOBP_Positive_Regulation_Of_Interferon_Alpha_Production	Mouse	Brain	rep_7	2.7e-21
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Production	Mouse	Brain	rep_7	2.6e-23
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep3	2.6e-16
Irf3	GOBP_Cytoplasmic_Pattern_Recognition_Receptor_Signaling_Pathway_In_Response_To_Virus	Mouse	Brain	HP_ad_rep3	1.8e-09
Irf3	GOBP_Myeloid_Cell_Apoptotic_Process	Mouse	Brain	HP_ad_rep3	6.0e-09
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Brain	HP_ad_rep3	1.6e-08
Irf3	GOBP_Response_To_Dsrna	Mouse	Brain	HP_ad_rep3	9.6e-11
Irf3	GOBP_Cellular_Response_To_Biotic_Stimulus	Mouse	Brain	HP_ad_rep7	2.8e-09
Irf3	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	HP_ad_rep7	6.8e-10
Irf3	GOBP_Cellular_Response_To_Dsrna	Mouse	Brain	HP_ad_rep7	1.5e-15
Irf3	GOBP_Cellular_Response_To_Exogenous_Dsrna	Mouse	Brain	HP_ad_rep7	7.8e-20
Irf3	GOBP_Cellular_Response_To_Lipid	Mouse	Brain	HP_ad_rep7	5.4e-08
Irf3	GOBP_Cellular_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Brain	HP_ad_rep7	1.1e-09
Irf3	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Brain	HP_ad_rep7	2.8e-12
Irf3	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Brain	HP_ad_rep7	2.6e-09
Irf3	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Brain	HP_ad_rep7	2.6e-10
Irf3	GOBP_Cellular_Response_To_Virus	Mouse	Brain	HP_ad_rep7	9.8e-07
Irf3	GOBP_Defense_Response	Mouse	Brain	HP_ad_rep7	5.6e-10
Irf3	GOBP_Interferon_Alpha_Production	Mouse	Brain	HP_ad_rep7	9.7e-07
Irf3	GOBP_Interferon_Beta_Production	Mouse	Brain	HP_ad_rep7	5.4e-08
Irf3	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	2.5e-10
Irf3	GOBP_Leukocyte_Apoptotic_Process	Mouse	Brain	HP_ad_rep7	3.5e-07
Irf3	GOBP_Mda_5_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	7.1e-07
Irf3	GOBP_Necrotic_Cell_Death	Mouse	Brain	HP_ad_rep7	4.4e-08
Irf3	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.3e-12
Irf3	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Brain	HP_ad_rep7	2.1e-08
Irf3	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-11
Irf3	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.1e-13
Irf3	GOBP_Negative_Regulation_Of_Type_I_Interferon_Production	Mouse	Brain	HP_ad_rep7	2.2e-15
Irf3	GOBP_Pattern_Recognition_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	2.1e-10
Irf3	GOBP_Positive_Regulation_Of_Defense_Response	Mouse	Brain	HP_ad_rep7	1.7e-14
Irf3	GOBP_Positive_Regulation_Of_Gene_Expression	Mouse	Brain	HP_ad_rep7	4.4e-07
Irf3	GOBP_Positive_Regulation_Of_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Brain	HP_ad_rep7	1.9e-07
Irf3	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Brain	HP_ad_rep7	4.6e-07
Irf3	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	5.5e-07
Irf3	GOBP_Positive_Regulation_Of_Interferon_Alpha_Production	Mouse	Brain	HP_ad_rep7	1.2e-09
Irf3	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	HP_ad_rep7	9.1e-08
Irf3	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-11
Irf3	GOBP_Positive_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Brain	HP_ad_rep7	1.6e-17
Irf3	GOBP_Positive_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Brain	HP_ad_rep7	2.2e-09
Irf3	GOBP_Positive_Regulation_Of_Response_To_External_Stimulus	Mouse	Brain	HP_ad_rep7	6.8e-12
Irf3	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.3e-11
Irf3	GOBP_Regulation_Of_Cell_Death	Mouse	Brain	HP_ad_rep7	1.6e-07
Irf3	GOBP_Regulation_Of_Defense_Response	Mouse	Brain	HP_ad_rep7	1.9e-09
Irf3	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	HP_ad_rep7	2.1e-11
Irf3	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	1.8e-09
Irf3	GOBP_Regulation_Of_Inflammatory_Response	Mouse	Brain	HP_ad_rep7	1.9e-11
Irf3	GOBP_Regulation_Of_Response_To_External_Stimulus	Mouse	Brain	HP_ad_rep7	1.3e-10
Irf3	GOBP_Regulation_Of_Response_To_Stress	Mouse	Brain	HP_ad_rep7	5.4e-09
Irf3	GOBP_Response_To_Cytokine	Mouse	Brain	HP_ad_rep7	2.1e-08
Irf3	GOBP_Response_To_Interferon_Gamma	Mouse	Brain	HP_ad_rep7	2.2e-09
Irf3	GOBP_Response_To_Lipid	Mouse	Brain	HP_ad_rep7	3.5e-07
Irf3	GOBP_Response_To_Molecule_Of_Bacterial_Origin	Mouse	Brain	HP_ad_rep7	4.5e-13
Irf3	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	HP_ad_rep7	3.5e-10
Irf3	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Brain	HP_ad_rep7	1.4e-09
Irf3	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Brain	HP_ad_rep7	4.2e-09
Irf3	GOBP_Response_To_Virus	Mouse	Brain	HP_ad_rep7	8.2e-09
Irf3	GOBP_Type_I_Interferon_Production	Mouse	Brain	HP_ad_rep7	1.1e-07
Irf3	GOBP_Inflammatory_Cell_Apoptotic_Process	Mouse	Brain	HP_adpolb_rep2	1.2e-12
Irf3	GOBP_Macrophage_Apoptotic_Process	Mouse	Brain	HP_adpolb_rep2	2.2e-10
Irf3	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	HP_polb_rep9	1.1e-12
Irf3	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	5.5e-07
Irf3	GOBP_Cytokine_Production	Mouse	Brain	HP_polb_rep9	1.6e-09
Irf3	GOBP_Defense_Response_To_Other_Organism	Mouse	Brain	HP_polb_rep9	2.1e-11
Irf3	GOBP_I_Kappab_Kinase_Nf_Kappab_Signaling	Mouse	Brain	HP_polb_rep9	1.8e-10
Irf3	GOBP_Immune_Effector_Process	Mouse	Brain	HP_polb_rep9	1.0e-08
Irf3	GOBP_Inflammatory_Response	Mouse	Brain	HP_polb_rep9	2.0e-10
Irf3	GOBP_Innate_Immune_Response	Mouse	Brain	HP_polb_rep9	3.9e-11
Irf3	GOBP_Interferon_Gamma_Mediated_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	4.9e-14
Irf3	GOBP_Lipopolysaccharide_Mediated_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	1.6e-08
Irf3	GOBP_Myd88_Independent_Toll_Like_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	5.8e-11
Irf3	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	HP_polb_rep9	1.8e-08
Irf3	GOBP_Positive_Regulation_Of_Cytokine_Production	Mouse	Brain	HP_polb_rep9	1.9e-09
Irf3	GOBP_Positive_Regulation_Of_Interferon_Beta_Production	Mouse	Brain	HP_polb_rep9	3.3e-11
Irf3	GOBP_Positive_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	1.7e-14
Irf3	GOBP_Positive_Regulation_Of_Signaling	Mouse	Brain	HP_polb_rep9	1.3e-14
Irf3	GOBP_Positive_Regulation_Of_Type_I_Interferon_Production	Mouse	Brain	HP_polb_rep9	1.2e-09
Irf3	GOBP_Programmed_Necrotic_Cell_Death	Mouse	Brain	HP_polb_rep9	9.6e-11
Irf3	GOBP_Regulation_Of_Innate_Immune_Response	Mouse	Brain	HP_polb_rep9	2.5e-14
Irf3	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	3.9e-11
Irf3	GOBP_Regulation_Of_Response_To_Biotic_Stimulus	Mouse	Brain	HP_polb_rep9	8.1e-15
Irf3	GOBP_Regulation_Of_Response_To_Cytokine_Stimulus	Mouse	Brain	HP_polb_rep9	1.5e-09
Irf3	GOBP_Regulation_Of_Type_I_Interferon_Mediated_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	8.9e-12
Irf3	GOBP_Response_To_Bacterium	Mouse	Brain	HP_polb_rep9	4.4e-08
Irf3	GOBP_Response_To_Type_I_Interferon	Mouse	Brain	HP_polb_rep9	5.2e-13
Irf3	GOBP_Toll_Like_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	2.4e-13

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Irf3 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Irf3 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Irf3 envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
Irf3	Kidney	LPS	TAL	Hdac5,Arf2,Meis2, etc.	0.366
Irf3	Kidney	LPS	PT_S3_C	Hdac5,Arf2,Meis2, etc.	0.261
Irf3	Kidney	LPS	CD_IC	Hdac5,Arf2,Meis2, etc.	0.275
Irf3	Kidney	LPS	CD_PC	Hdac5,Arf2,Meis2, etc.	0.268
IRF3	Uterus	early	Glandular	LTBP4,RAB4B,FKBP14, etc.	0.321
IRF3	Uterus	early	Glandular_secretory	LTBP4,RAB4B,FKBP14, etc.	0.265
IRF3	Uterus	early	SOX9_LGR5	LTBP4,RAB4B,FKBP14, etc.	0.361
IRF3	Uterus	early	SOX9	LTBP4,RAB4B,FKBP14, etc.	0.446
IRF3	Uterus	early_mid	Glandular	ASS1,ZNF597,PTPN21, etc.	0.355
IRF3	Uterus	early_mid	Lumenal 1	ASS1,ZNF597,PTPN21, etc.	0.511
IRF3	Uterus	early_mid	Glandular_secretory	ASS1,ZNF597,PTPN21, etc.	0.264
IRF3	Skin	tumor	T_cells	SIT1,CLECL1,CCL21, etc.	0.458
IRF3	Skin	tumor	Neurons	SIT1,CLECL1,CCL21, etc.	0.389
IRF3	Uterus	mid	Glandular_secretory	TRPM7,KLF8,ATF7IP, etc.	0.723
IRF3	Uterus	mid	Glandular	TRPM7,KLF8,ATF7IP, etc.	0.286
IRF3	Uterus	late	Glandular_secretory	AVEN,SETD5,RMI1, etc.	0.73
IRF3	Uterus	late	Ciliated	AVEN,SETD5,RMI1, etc.	0.286
IRF3	Intestine	development	Epithelium	RRBP1,PRPF4B,SH2B2, etc.	0.419
IRF3	Intestine	development	Fibroblasts	RRBP1,PRPF4B,SH2B2, etc.	0.437
IRF3	Intestine	development	MyoFibroblasts	RRBP1,PRPF4B,SH2B2, etc.	0.284
IRF3	Intestine	development	Neural	RRBP1,PRPF4B,SH2B2, etc.	0.254
Irf3	Lymph	control	Ifit3 high B	Slc15a3,Acsl1,Naglu, etc.	0.272
Irf3	Lymph	control	Mature B	Slc15a3,Acsl1,Naglu, etc.	0.366
Irf3	Lymph	control	Low quality B cells	Slc15a3,Acsl1,Naglu, etc.	0.255
Irf3	Kidney	IRI	PT_S1	Rbms3,Abcc5,Arfgap2, etc.	0.3
Irf3	Kidney	IRI	PT_S3_C	Rbms3,Abcc5,Arfgap2, etc.	0.282
Irf3	Kidney	IRI	PT_Fibrinogen	Rbms3,Abcc5,Arfgap2, etc.	0.264
Irf3	Kidney	IRI	CD_IC	Rbms3,Abcc5,Arfgap2, etc.	0.287
Irf3	Kidney	IRI	TAL	Rbms3,Abcc5,Arfgap2, etc.	0.279
Irf3	Kidney	IRI	CD_PC	Rbms3,Abcc5,Arfgap2, etc.	0.262
Irf3	Lymph	disease	Ifit3 high B	Gzma,Plpp1,Herc1, etc.	0.319
Irf3	Lymph	disease	CD4 T	Gzma,Plpp1,Herc1, etc.	0.255
Irf3	Lymph	disease	Mature B	Gzma,Plpp1,Herc1, etc.	0.363
IRF3	Uterus	proliferative	SOX9	NFATC1,ING1,PRR14, etc.	0.529
IRF3	Uterus	proliferative	SOX9_LGR5	NFATC1,ING1,PRR14, etc.	0.316
IRF3	Uterus	proliferative	SOX9_prolif	NFATC1,ING1,PRR14, etc.	0.35
Irf3	Kidney	Sham	PT_S3_OS	Smarca1,Klhl14,Vgll4, etc.	0.26
Irf3	Kidney	Sham	PT_S3_C	Smarca1,Klhl14,Vgll4, etc.	0.355
Irf3	Kidney	Sham	PT_Fibrinogen	Smarca1,Klhl14,Vgll4, etc.	0.277
Irf3	Kidney	Sham	VSM	Smarca1,Klhl14,Vgll4, etc.	0.26
Irf3	Kidney	Sham	PT_S1	Smarca1,Klhl14,Vgll4, etc.	0.265
Irf3	Kidney	Sham	TAL	Smarca1,Klhl14,Vgll4, etc.	0.316

Motif information.

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Related Drugs for Irf3

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Irf3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Irf3	C4225294	ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 7	2	GENOMICS_ENGLAND;UNIPROT