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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Hs6st2 (spascer ID:50786)

Gene summary for Hs6st2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Hs6st2
	Gene ID	50786
	Gene name	heparan sulfate 6-O-sulfotransferase 2
	Synonyms	6OST2
	Cytomap	X\|X A5
	Type of gene	protein-coding
	Description	heparan-sulfate 6-O-sulfotransferase 2
	Modification date	20220424
	UniProtAcc	Q80UW0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Hs6st2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	21873635	Process
Hs6st2	GO:0017095	heparan sulfate 6-O-sulfotransferase activity	21873635	Function

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Spatial pattern events for Hs6st2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Hs6st2	Mouse	Brain	S1	34413515	2.07e-15
Hs6st2	Mouse	Brain	S2	34413515	1.56e-15
Hs6st2	Mouse	Brain	S3	34413515	1.64e-15
Hs6st2	Mouse	Brain	S4	34413515	1.37e-15
Hs6st2	Mouse	Brain	S6	34413515	1.46e-15
Hs6st2	Mouse	Brain	S7	34413515	1.55e-15
Hs6st2	Mouse	Brain	01B	32637622	3.40e-08
Hs6st2	Mouse	Brain	05A	32637622	2.03e-10
Hs6st2	Mouse	Brain	06B	32637622	5.29e-08
Hs6st2	Mouse	Brain	07A	32637622	5.38e-07
Hs6st2	Mouse	Brain	08A	32637622	9.32e-12
Hs6st2	Mouse	Brain	17A	32637622	4.22e-06
Hs6st2	Mouse	Brain	17B	32637622	4.65e-06
Hs6st2	Mouse	Brain	18A	32637622	1.99e-06
Hs6st2	Mouse	Brain	20A	32637622	8.93e-06
Hs6st2	Mouse	Brain	22A	32637622	2.32e-08
Hs6st2	Mouse	Brain	22B	32637622	2.52e-08
Hs6st2	Mouse	Brain	24B	32637622	3.11e-11
Hs6st2	Mouse	Brain	25A	32637622	1.24e-13
Hs6st2	Mouse	Brain	27A	32637622	2.01e-12
Hs6st2	Mouse	Brain	27B	32637622	4.77e-12
Hs6st2	Mouse	Brain	28A	32637622	1.06e-14
Hs6st2	Mouse	Brain	28B	32637622	1.24e-14
Hs6st2	Mouse	Brain	29A	32637622	1.08e-14
Hs6st2	Mouse	Brain	29B	32637622	1.08e-14
Hs6st2	Mouse	Brain	30A	32637622	2.81e-13
Hs6st2	Mouse	Brain	31A	32637622	4.96e-07
Hs6st2	Mouse	Brain	32A	32637622	2.64e-14
Hs6st2	Mouse	Brain	33A	32637622	3.66e-10
Hs6st2	Mouse	Brain	34B	32637622	1.73e-08
Hs6st2	Mouse	Brain	35A	32637622	1.68e-07
Hs6st2	Mouse	Brain	35B	32637622	6.21e-07
Hs6st2	Mouse	Brain	36B	32637622	1.95e-10
Hs6st2	Mouse	Brain	rep_1	35141374	1.28e-13
Hs6st2	Mouse	Brain	rep_2	35141374	8.89e-14
Hs6st2	Mouse	Brain	rep_3	35141374	1.64e-15
Hs6st2	Mouse	Brain	rep_4	35141374	7.85e-11
Hs6st2	Mouse	Brain	rep_5	35141374	1.47e-15
Hs6st2	Mouse	Brain	rep_6	35141374	1.54e-13
Hs6st2	Mouse	Embryo	1E	34210887	6.72e-06
Hs6st2	Mouse	Embryo	4D	34210887	7.15e-06
Hs6st2	Mouse	Embryo	4E	34210887	1.25e-09
Hs6st2	Mouse	Embryo	rep_1	33188776	2.35e-06
Hs6st2	Mouse	Embryo	rep_4	33188776	5.08e-15
Hs6st2	Mouse	Embryo	rep_13	33188776	1.05e-10
Hs6st2	Mouse	Kidney	CLP	34003797	2.19e-15
Hs6st2	Mouse	Kidney	Sham	34003797	2.58e-15
Hs6st2	Mouse	Brain	rep_1	33469025	1.30e-15
Hs6st2	Mouse	Brain	rep_1	35027729	1.66e-15
Hs6st2	Mouse	Brain	rep_2	35027729	1.57e-15
Hs6st2	Mouse	Brain	rep_3	35027729	1.32e-15
Hs6st2	Mouse	Brain	rep_4	35027729	1.76e-15
Hs6st2	Mouse	Brain	rep_5	35027729	1.46e-15
Hs6st2	Mouse	Brain	B02_D1	32702314	2.50e-14
Hs6st2	Mouse	Brain	B02_E1	32702314	4.98e-06
Hs6st2	Mouse	Brain	B03_D2	32702314	9.54e-09
Hs6st2	Mouse	Brain	N02_C1	32702314	5.78e-07
Hs6st2	Mouse	Brain	N02_D1	32702314	3.17e-09
Hs6st2	Mouse	Brain	N03_D2	32702314	2.33e-14
Hs6st2	Mouse	Brain	N04_D1	32702314	9.75e-06
Hs6st2	Mouse	Brain	N04_E1	32702314	3.44e-07
Hs6st2	Mouse	Brain	N05_D2	32702314	2.23e-07
Hs6st2	Mouse	Brain	N07_C1	32702314	6.63e-07
Hs6st2	Mouse	Lymph	A1	0	1.98e-06
Hs6st2	Mouse	Brain	rep_1	35210624	1.74e-15
Hs6st2	Mouse	Brain	rep_2	35210624	1.74e-15
Hs6st2	Mouse	Brain	rep_3	35210624	1.82e-15
Hs6st2	Mouse	Brain	rep_4	35210624	8.30e-13
Hs6st2	Mouse	Brain	rep_5	35210624	2.07e-15
Hs6st2	Mouse	Brain	rep_6	35210624	2.05e-15
Hs6st2	Mouse	Brain	rep_7	35210624	1.87e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_Sham_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_D1_H&E
Brain_B02_E1_H&E
Brain_B03_D2_H&E
Brain_N02_C1_H&E
Brain_N02_D1_H&E
Brain_N03_D2_H&E
Brain_N04_D1_H&E
Brain_N04_E1_H&E
Brain_N05_D2_H&E
Brain_N07_C1_H&E

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Spatial pattern pathway has Hs6st2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Hs6st2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Spinal cord	CN94_E1	3.5e-06
Hs6st2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Spinal cord	L7bCN01_D2	9.0e-06
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process_Enzymatic_Modification	Mouse	Spinal cord	L7bCN05_D1	8.4e-06
Hs6st2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Hs6st2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-06
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.2e-06
Hs6st2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Hs6st2	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	2.3e-06
Hs6st2	GOBP_Proteoglycan_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.1e-06
Hs6st2	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Spinal cord	L7CN47_C1	1.3e-06
Hs6st2	GOBP_Aminoglycan_Metabolic_Process	Mouse	Spinal cord	L7CN47_D1	4.0e-07
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_19	7.6e-05
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process_Enzymatic_Modification	Mouse	Brain	rep_23	1.7e-06
Hs6st2	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Brain	rep_27	4.3e-05
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_74	5.3e-05
Hs6st2	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_74	9.0e-05
Hs6st2	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Brain	rep_1	2.1e-28
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process_Enzymatic_Modification	Mouse	Brain	rep_1	4.5e-41
Hs6st2	GOBP_Aminoglycan_Metabolic_Process	Mouse	Brain	rep_3	3.9e-113
Hs6st2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Brain	rep_3	2.7e-27
Hs6st2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Hs6st2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Brain	rep_3	6.4e-155
Hs6st2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Brain	rep_3	1.9e-173
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_3	1.6e-113
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_3	2.2e-99
Hs6st2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Hs6st2	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Brain	rep_3	3.5e-98
Hs6st2	GOBP_Proteoglycan_Metabolic_Process	Mouse	Brain	rep_3	4.8e-70
Hs6st2	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Embryo	rep_14	1.4e-44
Hs6st2	GOBP_Aminoglycan_Metabolic_Process	Mouse	Embryo	rep_14	8.7e-35
Hs6st2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Embryo	rep_14	4.5e-09
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Embryo	rep_14	3.8e-33
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process_Enzymatic_Modification	Mouse	Embryo	rep_14	1.9e-16
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Embryo	rep_14	1.5e-45
Hs6st2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Hs6st2	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Embryo	rep_14	8.9e-07
Hs6st2	GOBP_Proteoglycan_Metabolic_Process	Mouse	Embryo	rep_14	2.0e-20
Hs6st2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Kidney	rep_2	1.3e-08
Hs6st2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Hs6st2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Kidney	rep_2	2.5e-89
Hs6st2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Kidney	rep_2	1.1e-102
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Kidney	rep_2	4.1e-08
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process_Enzymatic_Modification	Mouse	Kidney	rep_2	2.5e-20
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-10
Hs6st2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Hs6st2	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Kidney	rep_2	1.1e-51
Hs6st2	GOBP_Proteoglycan_Metabolic_Process	Mouse	Kidney	rep_2	7.2e-30
Hs6st2	GOBP_Aminoglycan_Metabolic_Process	Mouse	Liver	CN73-C1	9.1e-08
Hs6st2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Liver	CN73-C1	3.2e-07
Hs6st2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Hs6st2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Liver	CN73-C1	9.7e-08
Hs6st2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Liver	CN73-C1	1.4e-07
Hs6st2	GOBP_Aminoglycan_Metabolic_Process	Mouse	Liver	rep_16	2.1e-07
Hs6st2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Liver	rep_16	2.6e-08
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process_Enzymatic_Modification	Mouse	Brain	rep_1	8.8e-25
Hs6st2	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Lymph	MS-1	3.1e-16
Hs6st2	GOBP_Aminoglycan_Metabolic_Process	Mouse	Lymph	MS-1	2.1e-14
Hs6st2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Hs6st2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Lymph	MS-1	4.4e-07
Hs6st2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Lymph	MS-1	1.1e-07
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process	Mouse	Lymph	MS-1	3.1e-07
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process_Enzymatic_Modification	Mouse	Lymph	MS-1	3.6e-11
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Lymph	MS-1	1.5e-11
Hs6st2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Hs6st2	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Lymph	MS-1	3.6e-20
Hs6st2	GOBP_Proteoglycan_Metabolic_Process	Mouse	Lymph	MS-1	7.9e-14
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Metabolic_Process	Mouse	Lung	rep_1	2.2e-08
Hs6st2	GOBP_Proteoglycan_Biosynthetic_Process	Mouse	Lung	rep_1	5.9e-09
Hs6st2	GOBP_Proteoglycan_Metabolic_Process	Mouse	Lung	rep_1	1.1e-19
Hs6st2	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Brain	rep_4	1.4e-08
Hs6st2	GOBP_Heparan_Sulfate_Proteoglycan_Biosynthetic_Process_Enzymatic_Modification	Mouse	Brain	HP_ad_rep3	5.0e-12
Hs6st2	GOBP_Aminoglycan_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	7.9e-08
Hs6st2	GOBP_Aminoglycan_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.6e-11
Hs6st2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	9.8e-07
Hs6st2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Hs6st2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Brain	HP_adpolb_rep1	2.0e-07
Hs6st2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Hs6st2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.4e-10

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Hs6st2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Hs6st2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Hs6st2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Hs6st2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Hs6st2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source