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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Rgs11 (spascer ID:50782)

Gene summary for Rgs11

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Rgs11
	Gene ID	50782
	Gene name	regulator of G-protein signaling 11
	Synonyms	C78048
	Cytomap	17\|17 A3.3
	Type of gene	protein-coding
	Description	regulator of G-protein signaling 11
	Modification date	20220503
	UniProtAcc	Q9Z2H1

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for Rgs11

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Rgs11	Mouse	Brain	S2	34413515	2.85e-15
Rgs11	Mouse	Brain	S4	34413515	1.37e-15
Rgs11	Mouse	Brain	S6	34413515	2.66e-15
Rgs11	Mouse	Brain	S7	34413515	2.85e-15
Rgs11	Mouse	Brain	rep_1	35141374	8.78e-06
Rgs11	Mouse	Brain	rep_4	35141374	3.29e-06
Rgs11	Mouse	Kidney	CLP	34003797	6.92e-15
Rgs11	Mouse	Kidney	rep_1	34853151	2.42e-15
Rgs11	Mouse	Brain	rep_1	33469025	1.30e-15
Rgs11	Mouse	Brain	rep_1	35027729	9.60e-09
Rgs11	Mouse	Brain	rep_2	35027729	8.03e-13
Rgs11	Mouse	Brain	rep_3	35027729	1.13e-07
Rgs11	Mouse	Brain	rep_5	35027729	3.33e-07
Rgs11	Mouse	Brain	rep_1	35210624	1.74e-15
Rgs11	Mouse	Brain	rep_2	35210624	1.72e-13
Rgs11	Mouse	Brain	rep_6	35210624	4.89e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_4_H&E
Kidney_CLP_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Rgs11 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Rgs11	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	2.5e-06
Rgs11	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	8.8e-08
Rgs11	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Rgs11	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Spinal cord	L7CN45_C1	7.5e-06
Rgs11	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	1.8e-08
Rgs11	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Rgs11	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	2.3e-07
Rgs11	GOBP_Negative_Regulation_Of_Signaling	Mouse	Spinal cord	L8CN17_E1	8.3e-06
Rgs11	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_27	8.0e-06
Rgs11	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_27	4.5e-08
Rgs11	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_27	4.2e-05
Rgs11	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	4.5e-16
Rgs11	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	2.1e-36
Rgs11	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_1	1.0e-11
Rgs11	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	2.4e-43
Rgs11	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	5.6e-32
Rgs11	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	rep_3	1.3e-138
Rgs11	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	rep_3	7.8e-106
Rgs11	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_3	8.5e-79
Rgs11	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	rep_3	2.6e-94
Rgs11	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_3	1.4e-120
Rgs11	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_14	8.5e-07
Rgs11	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Embryo	rep_1	1.1e-25
Rgs11	GOBP_Negative_Regulation_Of_Signaling	Mouse	Embryo	rep_1	5.6e-10
Rgs11	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Embryo	rep_1	2.2e-98
Rgs11	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_1	1.6e-15
Rgs11	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Embryo	rep_3	0.0e+00
Rgs11	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Embryo	rep_3	4.4e-96
Rgs11	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	Nep	4.2e-26
Rgs11	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	Nep	1.8e-46
Rgs11	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.4e-48
Rgs11	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	Nep	1.8e-46
Rgs11	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	Nep	4.2e-26
Rgs11	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.3e-36
Rgs11	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	3.0e-37
Rgs11	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Kidney	rep_2	1.7e-39
Rgs11	GOBP_Negative_Regulation_Of_Signaling	Mouse	Kidney	rep_2	4.0e-40
Rgs11	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	rep_2	2.1e-66
Rgs11	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	2.1e-81
Rgs11	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	3.6e-50
Rgs11	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	rep_2	2.2e-45
Rgs11	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	3.4e-47
Rgs11	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	1.2e-71
Rgs11	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	1.4e-60
Rgs11	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Liver	CN16-D2	1.9e-10
Rgs11	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	7.2e-08
Rgs11	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	1.8e-08
Rgs11	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Lymph	MS-1	1.5e-11
Rgs11	GOBP_Negative_Regulation_Of_Signaling	Mouse	Lymph	MS-1	1.0e-14
Rgs11	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Lymph	MS-1	2.2e-13
Rgs11	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Lymph	MS-1	1.9e-12
Rgs11	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Lymph	MS-1	1.9e-08
Rgs11	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_4	1.7e-17
Rgs11	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_4	7.8e-12
Rgs11	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_4	3.8e-61
Rgs11	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	HP_ad_rep7	2.8e-07
Rgs11	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_ad_rep7	4.8e-07
Rgs11	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	HP_ad_rep7	2.8e-07
Rgs11	GOBP_Regulation_Of_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	2.3e-11
Rgs11	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	6.4e-16
Rgs11	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	HP_polb_rep9	3.1e-09
Rgs11	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	HP_polb_rep9	1.4e-11
Rgs11	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_polb_rep9	4.2e-09
Rgs11	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_polb_rep9	6.0e-09
Rgs11	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_wt_rep2	2.1e-07

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Rgs11 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Rgs11 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Rgs11 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Rgs11

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Rgs11

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source