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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Fbxo8 (spascer ID:50753)

Gene summary for Fbxo8

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Fbxo8
	Gene ID	50753
	Gene name	F-box protein 8
	Synonyms	Fbx8
	Cytomap	8\|8 B2
	Type of gene	protein-coding
	Description	F-box only protein 8
	Modification date	20220424
	UniProtAcc	Q9QZN3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for Fbxo8

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Fbxo8	Mouse	Brain	S6	34413515	3.10e-08
Fbxo8	Mouse	Kidney	CLP	34003797	7.59e-12
Fbxo8	Mouse	Kidney	IRI	34003797	2.03e-13

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_IRI_H&E

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Spatial pattern pathway has Fbxo8 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Fbxo8	GOBP_Arf_Protein_Signal_Transduction	Mouse	Spinal cord	L7CN45_C1	8.8e-08
Fbxo8	GOBP_Macromolecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	7.5e-06
Fbxo8	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Fbxo8	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Fbxo8	GOBP_Protein_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Fbxo8	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Fbxo8	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Fbxo8	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L8CN11_D1	5.6e-09
Fbxo8	GOBP_Ras_Protein_Signal_Transduction	Mouse	Spinal cord	L8CN17_E1	6.9e-06
Fbxo8	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_27	3.9e-05
Fbxo8	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_27	6.4e-05
Fbxo8	GOBP_Arf_Protein_Signal_Transduction	Mouse	Brain	rep_1	8.6e-91
Fbxo8	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_1	1.1e-11
Fbxo8	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.2e-13
Fbxo8	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.1e-22
Fbxo8	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Brain	rep_3	2.9e-162
Fbxo8	GOBP_Macromolecule_Catabolic_Process	Mouse	Brain	rep_3	1.7e-159
Fbxo8	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Brain	rep_3	8.7e-167
Fbxo8	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	rep_3	7.1e-166
Fbxo8	GOBP_Protein_Catabolic_Process	Mouse	Brain	rep_3	3.0e-174
Fbxo8	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
Fbxo8	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	1.3e-132
Fbxo8	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_3	8.3e-130
Fbxo8	GOBP_Arf_Protein_Signal_Transduction	Mouse	Embryo	rep_14	7.8e-28
Fbxo8	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Embryo	rep_1	7.5e-10
Fbxo8	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Embryo	rep_1	5.7e-21
Fbxo8	GOBP_Protein_Catabolic_Process	Mouse	Embryo	rep_1	4.1e-19
Fbxo8	GOBP_Ras_Protein_Signal_Transduction	Mouse	Embryo	rep_3	5.2e-68
Fbxo8	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Embryo	rep_3	5.2e-68
Fbxo8	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
Fbxo8	GOBP_Arf_Protein_Signal_Transduction	Mouse	Kidney	rep_2	3.4e-15
Fbxo8	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Kidney	rep_2	3.2e-21
Fbxo8	GOBP_Macromolecule_Catabolic_Process	Mouse	Kidney	rep_2	7.0e-40
Fbxo8	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Kidney	rep_2	1.0e-26
Fbxo8	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Kidney	rep_2	1.2e-14
Fbxo8	GOBP_Protein_Catabolic_Process	Mouse	Kidney	rep_2	7.3e-30
Fbxo8	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
Fbxo8	GOBP_Ras_Protein_Signal_Transduction	Mouse	Kidney	rep_2	3.5e-92
Fbxo8	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	1.4e-17
Fbxo8	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Kidney	rep_2	4.4e-65
Fbxo8	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.0e-93
Fbxo8	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.2e-75
Fbxo8	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Liver	CN16-D2	1.3e-07
Fbxo8	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
Fbxo8	GOBP_Macromolecule_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Fbxo8	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
Fbxo8	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Fbxo8	GOBP_Protein_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
Fbxo8	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
Fbxo8	GOBP_Ras_Protein_Signal_Transduction	Mouse	Lymph	MS-1	1.1e-08
Fbxo8	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.0e-14
Fbxo8	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Lymph	MS-1	3.8e-08
Fbxo8	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Lymph	MS-1	3.5e-10
Fbxo8	GOBP_Macromolecule_Catabolic_Process	Mouse	Lung	rep_1	2.0e-21
Fbxo8	GOBP_Arf_Protein_Signal_Transduction	Mouse	Brain	rep_4	1.2e-17
Fbxo8	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_4	1.0e-16
Fbxo8	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_4	6.8e-16
Fbxo8	GOBP_Macromolecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-09
Fbxo8	GOBP_Modification_Dependent_Macromolecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-08
Fbxo8	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Fbxo8	GOBP_Protein_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Fbxo8	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
Fbxo8	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_ad_rep7	4.6e-08
Fbxo8	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Brain	HP_adpolb_rep1	7.2e-07
Fbxo8	GOBP_Arf_Protein_Signal_Transduction	Mouse	Brain	HP_polb_rep9	1.2e-11
Fbxo8	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	HP_polb_rep9	7.2e-09
Fbxo8	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	3.9e-11
Fbxo8	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Brain	HP_polb_rep9	4.3e-10
Fbxo8	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_polb_rep9	5.2e-07

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Fbxo8 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Fbxo8 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Fbxo8 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Fbxo8

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Fbxo8

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source