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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Arhgap32 (spascer ID:330914)

Gene summary for Arhgap32

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Arhgap32
	Gene ID	330914
	Gene name	Rho GTPase activating protein 32
	Synonyms	3426406O18Rik\|Gc-gap\|Grit\|Px-rics\|Rics\|mKIAA0712\|p200Rhogap\|p250Gap
	Cytomap	9\|9 A4
	Type of gene	protein-coding
	Description	rho GTPase-activating protein 32GAB-associated Cdc42/Rac GTPase-activating proteinGTPase-activating protein for Cdc42 and Rac1Rho GTPase activating protein 33 pseudogenebrain-specific Rho GTPase-activating proteinrac GTPase activating proteinrho-typ
	Modification date	20220424
	UniProtAcc	Q811P8

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Arhgap32	GO:0001650	fibrillar center	21873635	Component
Arhgap32	GO:0005096	GTPase activator activity	21873635	Function
Arhgap32	GO:0005654	nucleoplasm	21873635	Component
Arhgap32	GO:0005794	Golgi apparatus	21873635	Component
Arhgap32	GO:0005938	cell cortex	21873635	Component
Arhgap32	GO:0007264	small GTPase mediated signal transduction	21873635	Process
Arhgap32	GO:0015629	actin cytoskeleton	21873635	Component

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Spatial pattern events for Arhgap32

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Arhgap32	Mouse	Brain	S1	34413515	2.07e-15
Arhgap32	Mouse	Brain	S2	34413515	1.56e-15
Arhgap32	Mouse	Brain	S3	34413515	1.64e-15
Arhgap32	Mouse	Brain	S4	34413515	1.37e-15
Arhgap32	Mouse	Brain	S6	34413515	1.46e-15
Arhgap32	Mouse	Brain	S7	34413515	1.55e-15
Arhgap32	Mouse	Brain	01B	32637622	9.48e-13
Arhgap32	Mouse	Brain	05A	32637622	4.16e-07
Arhgap32	Mouse	Brain	06A	32637622	2.79e-09
Arhgap32	Mouse	Brain	06B	32637622	1.76e-06
Arhgap32	Mouse	Brain	07B	32637622	2.73e-07
Arhgap32	Mouse	Brain	09B	32637622	3.22e-10
Arhgap32	Mouse	Brain	10A	32637622	6.96e-06
Arhgap32	Mouse	Brain	11A	32637622	1.61e-14
Arhgap32	Mouse	Brain	12A	32637622	2.09e-14
Arhgap32	Mouse	Brain	12B	32637622	1.20e-14
Arhgap32	Mouse	Brain	13A	32637622	9.22e-06
Arhgap32	Mouse	Brain	13B	32637622	1.72e-14
Arhgap32	Mouse	Brain	14A	32637622	1.38e-14
Arhgap32	Mouse	Brain	14B	32637622	1.35e-14
Arhgap32	Mouse	Brain	15A	32637622	3.51e-13
Arhgap32	Mouse	Brain	15B	32637622	1.36e-12
Arhgap32	Mouse	Brain	16A	32637622	1.75e-14
Arhgap32	Mouse	Brain	16B	32637622	3.51e-14
Arhgap32	Mouse	Brain	17A	32637622	1.19e-14
Arhgap32	Mouse	Brain	17B	32637622	1.32e-14
Arhgap32	Mouse	Brain	18A	32637622	1.20e-14
Arhgap32	Mouse	Brain	18B	32637622	1.38e-14
Arhgap32	Mouse	Brain	19A	32637622	1.74e-12
Arhgap32	Mouse	Brain	19B	32637622	1.36e-14
Arhgap32	Mouse	Brain	20A	32637622	4.49e-10
Arhgap32	Mouse	Brain	20B	32637622	1.86e-10
Arhgap32	Mouse	Brain	21A	32637622	1.43e-14
Arhgap32	Mouse	Brain	21B	32637622	1.37e-14
Arhgap32	Mouse	Brain	22A	32637622	8.87e-15
Arhgap32	Mouse	Brain	22B	32637622	8.81e-15
Arhgap32	Mouse	Brain	23A	32637622	2.77e-14
Arhgap32	Mouse	Brain	23B	32637622	1.10e-14
Arhgap32	Mouse	Brain	24A	32637622	1.61e-14
Arhgap32	Mouse	Brain	24B	32637622	1.40e-14
Arhgap32	Mouse	Brain	25A	32637622	1.86e-14
Arhgap32	Mouse	Brain	26A	32637622	1.34e-14
Arhgap32	Mouse	Brain	26B	32637622	2.02e-14
Arhgap32	Mouse	Brain	27A	32637622	1.03e-14
Arhgap32	Mouse	Brain	27B	32637622	1.06e-14
Arhgap32	Mouse	Brain	28A	32637622	1.06e-14
Arhgap32	Mouse	Brain	28B	32637622	1.24e-14
Arhgap32	Mouse	Brain	29A	32637622	1.08e-14
Arhgap32	Mouse	Brain	29B	32637622	1.08e-14
Arhgap32	Mouse	Brain	30A	32637622	1.48e-14
Arhgap32	Mouse	Brain	31A	32637622	1.59e-14
Arhgap32	Mouse	Brain	32A	32637622	1.52e-14
Arhgap32	Mouse	Brain	33A	32637622	1.50e-14
Arhgap32	Mouse	Brain	33B	32637622	1.94e-14
Arhgap32	Mouse	Brain	34A	32637622	1.42e-14
Arhgap32	Mouse	Brain	34B	32637622	1.67e-14
Arhgap32	Mouse	Brain	35A	32637622	1.48e-14
Arhgap32	Mouse	Brain	35B	32637622	1.78e-14
Arhgap32	Mouse	Brain	rep_1	35141374	1.69e-14
Arhgap32	Mouse	Brain	rep_2	35141374	5.75e-11
Arhgap32	Mouse	Brain	rep_3	35141374	1.64e-15
Arhgap32	Mouse	Brain	rep_4	35141374	1.57e-15
Arhgap32	Mouse	Brain	rep_5	35141374	5.13e-15
Arhgap32	Mouse	Brain	rep_6	35141374	1.69e-12
Arhgap32	Mouse	Embryo	3F	34210887	4.27e-07
Arhgap32	Mouse	Brain	rep_1	33469025	4.18e-14
Arhgap32	Mouse	Brain	rep_1	35027729	1.66e-15
Arhgap32	Mouse	Brain	rep_2	35027729	1.57e-15
Arhgap32	Mouse	Brain	rep_3	35027729	1.32e-15
Arhgap32	Mouse	Brain	rep_4	35027729	1.76e-15
Arhgap32	Mouse	Brain	rep_5	35027729	1.46e-15
Arhgap32	Mouse	Brain	B02_D1	32702314	1.50e-14
Arhgap32	Mouse	Brain	B02_E1	32702314	1.33e-14
Arhgap32	Mouse	Brain	B03_C2	32702314	3.45e-14
Arhgap32	Mouse	Brain	B03_D2	32702314	2.13e-14
Arhgap32	Mouse	Brain	B04_D1	32702314	6.81e-12
Arhgap32	Mouse	Brain	B04_E1	32702314	2.89e-10
Arhgap32	Mouse	Brain	N02_C1	32702314	5.43e-08
Arhgap32	Mouse	Brain	N03_C2	32702314	2.55e-14
Arhgap32	Mouse	Brain	N03_D2	32702314	1.38e-14
Arhgap32	Mouse	Brain	N04_D1	32702314	3.81e-11
Arhgap32	Mouse	Brain	N04_E1	32702314	3.65e-14
Arhgap32	Mouse	Brain	N05_D2	32702314	3.79e-13
Arhgap32	Mouse	Brain	N07_C1	32702314	2.75e-12
Arhgap32	Mouse	Brain	rep_1	35210624	1.74e-15
Arhgap32	Mouse	Brain	rep_2	35210624	1.74e-15
Arhgap32	Mouse	Brain	rep_3	35210624	1.82e-15
Arhgap32	Mouse	Brain	rep_4	35210624	3.00e-14
Arhgap32	Mouse	Brain	rep_5	35210624	2.07e-15
Arhgap32	Mouse	Brain	rep_6	35210624	2.05e-15
Arhgap32	Mouse	Brain	rep_7	35210624	1.87e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_D1_H&E
Brain_B02_E1_H&E
Brain_B03_C2_H&E
Brain_B03_D2_H&E
Brain_B04_D1_H&E
Brain_B04_E1_H&E
Brain_N02_C1_H&E
Brain_N03_C2_H&E
Brain_N03_D2_H&E
Brain_N04_D1_H&E
Brain_N04_E1_H&E
Brain_N05_D2_H&E
Brain_N07_C1_H&E

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Spatial pattern pathway has Arhgap32 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Arhgap32	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Arhgap32	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Spinal cord	L7CN45_C1	7.5e-06
Arhgap32	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	1.8e-08
Arhgap32	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Arhgap32	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	2.3e-07
Arhgap32	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Arhgap32	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L8CN11_D1	5.6e-09
Arhgap32	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_27	4.2e-05
Arhgap32	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_27	6.4e-05
Arhgap32	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	2.1e-36
Arhgap32	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_1	1.0e-11
Arhgap32	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_1	5.6e-32
Arhgap32	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.2e-13
Arhgap32	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.1e-22
Arhgap32	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_3	8.5e-79
Arhgap32	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	rep_3	2.6e-94
Arhgap32	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_3	1.4e-120
Arhgap32	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	1.3e-132
Arhgap32	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_14	8.5e-07
Arhgap32	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Embryo	rep_1	2.2e-98
Arhgap32	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_1	1.6e-15
Arhgap32	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Embryo	rep_3	5.2e-68
Arhgap32	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	Nep	1.8e-46
Arhgap32	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.4e-48
Arhgap32	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	Nep	1.8e-46
Arhgap32	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.3e-36
Arhgap32	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Kidney	rep_2	2.1e-66
Arhgap32	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	2.1e-81
Arhgap32	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	3.6e-50
Arhgap32	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Kidney	rep_2	2.2e-45
Arhgap32	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Kidney	rep_2	1.2e-71
Arhgap32	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	1.4e-60
Arhgap32	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	1.4e-17
Arhgap32	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.0e-93
Arhgap32	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.2e-75
Arhgap32	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Liver	CN16-D2	1.9e-10
Arhgap32	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Liver	CN16-D2	1.3e-07
Arhgap32	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Lymph	MS-1	2.2e-13
Arhgap32	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Lymph	MS-1	1.9e-12
Arhgap32	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Lymph	MS-1	1.9e-08
Arhgap32	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.0e-14
Arhgap32	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Lymph	MS-1	3.5e-10
Arhgap32	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	rep_4	7.8e-12
Arhgap32	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_4	6.8e-16
Arhgap32	GOBP_Positive_Regulation_Of_Catalytic_Activity	Mouse	Brain	HP_ad_rep7	2.8e-07
Arhgap32	GOBP_Positive_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_ad_rep7	4.8e-07
Arhgap32	GOBP_Positive_Regulation_Of_Molecular_Function	Mouse	Brain	HP_ad_rep7	2.8e-07
Arhgap32	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_ad_rep7	4.6e-08
Arhgap32	GOBP_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_polb_rep9	4.2e-09
Arhgap32	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_polb_rep9	6.0e-09
Arhgap32	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	3.9e-11
Arhgap32	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_polb_rep9	5.2e-07
Arhgap32	GOBP_Positive_Regulation_Of_Gtpase_Activity	Mouse	Brain	HP_wt_rep2	2.1e-07

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Arhgap32 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Arhgap32 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Arhgap32 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Arhgap32

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Arhgap32

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Arhgap32	C0036341	Schizophrenia	1	PSYGENET