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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Col8a2 (spascer ID:329941)

Gene summary for Col8a2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Col8a2
	Gene ID	329941
	Gene name	collagen, type VIII, alpha 2
	Synonyms	AI429819
	Cytomap	4 D2.2\|4 60.29 cM
	Type of gene	protein-coding
	Description	collagen alpha-2(VIII) chainendothelial collagenprocollagen, type VIII, alpha 2
	Modification date	20220424
	UniProtAcc	P25318

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Col8a2	GO:0005201	extracellular matrix structural constituent	21873635	Function
Col8a2	GO:0005615	extracellular space	21873635	Component
Col8a2	GO:0030198	extracellular matrix organization	21873635	Process
Col8a2	GO:0031012	extracellular matrix	21873635	Component

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Spatial pattern events for Col8a2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Col8a2	Mouse	Brain	11A	32637622	1.61e-14
Col8a2	Mouse	Brain	12B	32637622	1.20e-14
Col8a2	Mouse	Brain	13B	32637622	7.74e-09
Col8a2	Mouse	Brain	23B	32637622	3.44e-08
Col8a2	Mouse	Brain	24A	32637622	2.45e-14
Col8a2	Mouse	Brain	24B	32637622	2.09e-10
Col8a2	Mouse	Embryo	2H	34210887	7.50e-09
Col8a2	Mouse	Embryo	rep_2	33188776	1.05e-13
Col8a2	Mouse	Embryo	rep_4	33188776	8.29e-15
Col8a2	Mouse	Embryo	rep_5	33188776	3.86e-14
Col8a2	Mouse	Brain	N02_C1	32702314	2.15e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_N02_C1_H&E

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Spatial pattern pathway has Col8a2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Col8a2	GOBP_Animal_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	6.6e-06
Col8a2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Spinal cord	CN94_E1	1.2e-06
Col8a2	GOBP_Sensory_Organ_Development	Mouse	Spinal cord	CN94_E1	4.5e-06
Col8a2	GOBP_Camera_Type_Eye_Morphogenesis	Mouse	Spinal cord	L7bCN02_E1	1.6e-07
Col8a2	GOBP_Eye_Morphogenesis	Mouse	Spinal cord	L7bCN02_E1	4.0e-07
Col8a2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Col8a2	GOBP_Biological_Adhesion	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Col8a2	GOBP_Blood_Vessel_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	1.0e-07
Col8a2	GOBP_Camera_Type_Eye_Development	Mouse	Spinal cord	L7CN45_C1	1.0e-08
Col8a2	GOBP_Cell_Cell_Adhesion	Mouse	Spinal cord	L7CN45_C1	6.8e-10
Col8a2	GOBP_Circulatory_System_Development	Mouse	Spinal cord	L7CN45_C1	5.7e-08
Col8a2	GOBP_Epithelial_Cell_Proliferation	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Col8a2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Col8a2	GOBP_Sensory_System_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Col8a2	GOBP_Tube_Development	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Col8a2	GOBP_Tube_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Col8a2	GOBP_Vasculature_Development	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Col8a2	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_27	2.0e-06
Col8a2	GOBP_Sensory_Organ_Development	Mouse	Brain	rep_27	4.9e-05
Col8a2	GOBP_Sensory_System_Development	Mouse	Brain	rep_27	1.2e-05
Col8a2	GOBP_Camera_Type_Eye_Development	Mouse	Brain	rep_72	4.7e-05
Col8a2	GOBP_Epithelial_Cell_Proliferation	Mouse	Brain	rep_72	3.4e-06
Col8a2	GOBP_Camera_Type_Eye_Development	Mouse	Brain	rep_1	2.1e-13
Col8a2	GOBP_Sensory_System_Development	Mouse	Brain	rep_1	1.6e-12
Col8a2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	rep_3	5.3e-58
Col8a2	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_3	5.4e-57
Col8a2	GOBP_Biological_Adhesion	Mouse	Brain	rep_3	4.3e-106
Col8a2	GOBP_Blood_Vessel_Morphogenesis	Mouse	Brain	rep_3	7.4e-87
Col8a2	GOBP_Camera_Type_Eye_Morphogenesis	Mouse	Brain	rep_3	1.1e-123
Col8a2	GOBP_Cell_Cell_Adhesion	Mouse	Brain	rep_3	5.2e-118
Col8a2	GOBP_Circulatory_System_Development	Mouse	Brain	rep_3	1.3e-81
Col8a2	GOBP_Epithelial_Cell_Proliferation	Mouse	Brain	rep_3	1.4e-179
Col8a2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Brain	rep_3	8.9e-180
Col8a2	GOBP_Eye_Morphogenesis	Mouse	Brain	rep_3	4.2e-134
Col8a2	GOBP_Sensory_Organ_Development	Mouse	Brain	rep_3	1.6e-123
Col8a2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Brain	rep_3	1.5e-133
Col8a2	GOBP_Tube_Development	Mouse	Brain	rep_3	9.0e-136
Col8a2	GOBP_Tube_Morphogenesis	Mouse	Brain	rep_3	4.7e-120
Col8a2	GOBP_Vasculature_Development	Mouse	Brain	rep_3	2.6e-82
Col8a2	GOBP_Circulatory_System_Development	Mouse	Embryo	rep_6	1.6e-12
Col8a2	GOBP_Camera_Type_Eye_Morphogenesis	Mouse	Embryo	rep_14	3.0e-07
Col8a2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Embryo	rep_14	7.1e-17
Col8a2	GOBP_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_1	1.7e-10
Col8a2	GOBP_Biological_Adhesion	Mouse	Embryo	rep_1	2.2e-19
Col8a2	GOBP_Camera_Type_Eye_Development	Mouse	Embryo	rep_1	2.6e-46
Col8a2	GOBP_Epithelial_Cell_Proliferation	Mouse	Embryo	rep_1	0.0e+00
Col8a2	GOBP_Sensory_System_Development	Mouse	Embryo	rep_1	1.3e-72
Col8a2	GOBP_Sensory_Organ_Development	Mouse	Embryo	rep_3	2.1e-266
Col8a2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Embryo	rep_3	9.1e-62
Col8a2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Embryo	rep_6	3.8e-28
Col8a2	GOBP_Blood_Vessel_Morphogenesis	Mouse	Embryo	rep_6	1.6e-86
Col8a2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Embryo	rep_6	1.1e-18
Col8a2	GOBP_Vasculature_Development	Mouse	Embryo	rep_6	1.9e-41
Col8a2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Col8a2	GOBP_Blood_Vessel_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Col8a2	GOBP_Circulatory_System_Development	Mouse	Kidney	Nep	5.6e-37
Col8a2	GOBP_Tube_Development	Mouse	Kidney	Nep	5.6e-37
Col8a2	GOBP_Tube_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Col8a2	GOBP_Vasculature_Development	Mouse	Kidney	Nep	5.6e-37
Col8a2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	rep_2	5.6e-148
Col8a2	GOBP_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	4.2e-71
Col8a2	GOBP_Biological_Adhesion	Mouse	Kidney	rep_2	1.3e-48
Col8a2	GOBP_Blood_Vessel_Morphogenesis	Mouse	Kidney	rep_2	3.2e-114
Col8a2	GOBP_Camera_Type_Eye_Morphogenesis	Mouse	Kidney	rep_2	2.7e-96
Col8a2	GOBP_Cell_Cell_Adhesion	Mouse	Kidney	rep_2	1.1e-24
Col8a2	GOBP_Circulatory_System_Development	Mouse	Kidney	rep_2	6.7e-139
Col8a2	GOBP_Epithelial_Cell_Proliferation	Mouse	Kidney	rep_2	1.8e-43
Col8a2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Kidney	rep_2	5.6e-85
Col8a2	GOBP_Eye_Morphogenesis	Mouse	Kidney	rep_2	1.2e-85
Col8a2	GOBP_Sensory_Organ_Development	Mouse	Kidney	rep_2	4.7e-27
Col8a2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Kidney	rep_2	3.2e-88
Col8a2	GOBP_Sensory_System_Development	Mouse	Kidney	rep_2	7.2e-08
Col8a2	GOBP_Tube_Development	Mouse	Kidney	rep_2	1.2e-129
Col8a2	GOBP_Tube_Morphogenesis	Mouse	Kidney	rep_2	2.1e-134
Col8a2	GOBP_Vasculature_Development	Mouse	Kidney	rep_2	2.3e-129
Col8a2	GOBP_Epithelial_Cell_Proliferation	Mouse	Liver	CN73-C1	1.7e-07
Col8a2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Liver	CN73-C1	1.4e-08
Col8a2	GOBP_Biological_Adhesion	Mouse	Liver	rep_16	2.1e-07
Col8a2	GOBP_Cell_Cell_Adhesion	Mouse	Liver	rep_16	1.4e-11
Col8a2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Lymph	MS-1	6.4e-13
Col8a2	GOBP_Animal_Organ_Morphogenesis	Mouse	Lymph	MS-1	4.4e-09
Col8a2	GOBP_Biological_Adhesion	Mouse	Lymph	MS-1	8.0e-14
Col8a2	GOBP_Blood_Vessel_Morphogenesis	Mouse	Lymph	MS-1	3.6e-10
Col8a2	GOBP_Camera_Type_Eye_Development	Mouse	Lymph	MS-1	3.1e-10
Col8a2	GOBP_Camera_Type_Eye_Morphogenesis	Mouse	Lymph	MS-1	4.0e-08
Col8a2	GOBP_Cell_Cell_Adhesion	Mouse	Lymph	MS-1	1.9e-13
Col8a2	GOBP_Circulatory_System_Development	Mouse	Lymph	MS-1	1.6e-11
Col8a2	GOBP_Epithelial_Cell_Proliferation	Mouse	Lymph	MS-1	1.0e-07
Col8a2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Lymph	MS-1	6.5e-12
Col8a2	GOBP_Eye_Morphogenesis	Mouse	Lymph	MS-1	1.6e-09
Col8a2	GOBP_Sensory_Organ_Development	Mouse	Lymph	MS-1	1.5e-10
Col8a2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Lymph	MS-1	3.6e-12
Col8a2	GOBP_Sensory_System_Development	Mouse	Lymph	MS-1	1.2e-07
Col8a2	GOBP_Tube_Development	Mouse	Lymph	MS-1	4.6e-09
Col8a2	GOBP_Tube_Morphogenesis	Mouse	Lymph	MS-1	9.1e-10
Col8a2	GOBP_Vasculature_Development	Mouse	Lymph	MS-1	3.0e-12
Col8a2	GOBP_Biological_Adhesion	Mouse	Lung	rep_1	3.0e-22
Col8a2	GOBP_Cell_Cell_Adhesion	Mouse	Lung	rep_1	2.9e-07
Col8a2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Lung	rep_1	1.3e-11
Col8a2	GOBP_Camera_Type_Eye_Development	Mouse	Brain	HP_ad_rep7	3.5e-12
Col8a2	GOBP_Camera_Type_Eye_Morphogenesis	Mouse	Brain	HP_ad_rep7	1.5e-09
Col8a2	GOBP_Epithelial_Cell_Proliferation	Mouse	Brain	HP_ad_rep7	8.1e-09
Col8a2	GOBP_External_Encapsulating_Structure_Organization	Mouse	Brain	HP_ad_rep7	1.9e-11
Col8a2	GOBP_Eye_Morphogenesis	Mouse	Brain	HP_ad_rep7	4.2e-07
Col8a2	GOBP_Sensory_Organ_Development	Mouse	Brain	HP_ad_rep7	4.6e-10
Col8a2	GOBP_Sensory_Organ_Morphogenesis	Mouse	Brain	HP_ad_rep7	9.0e-08
Col8a2	GOBP_Sensory_System_Development	Mouse	Brain	HP_ad_rep7	1.6e-11
Col8a2	GOBP_Tube_Development	Mouse	Brain	HP_ad_rep7	2.0e-08
Col8a2	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	HP_polb_rep9	6.3e-08
Col8a2	GOBP_Biological_Adhesion	Mouse	Brain	HP_polb_rep9	1.5e-07
Col8a2	GOBP_Blood_Vessel_Morphogenesis	Mouse	Brain	HP_polb_rep9	1.0e-11
Col8a2	GOBP_Cell_Cell_Adhesion	Mouse	Brain	HP_polb_rep9	3.6e-11
Col8a2	GOBP_Circulatory_System_Development	Mouse	Brain	HP_polb_rep9	3.1e-09
Col8a2	GOBP_Tube_Morphogenesis	Mouse	Brain	HP_polb_rep9	4.0e-10
Col8a2	GOBP_Vasculature_Development	Mouse	Brain	HP_polb_rep9	3.4e-10

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Col8a2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Col8a2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Col8a2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Col8a2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Col8a2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source