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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Zfp236 (spascer ID:329002)

Gene summary for Zfp236

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Zfp236

Gene ID

329002

Gene namezinc finger protein 236
SynonymsAI447957|Gm335
Cytomap18 E3|18 56.26 cM
Type of geneprotein-coding
Descriptionzinc finger protein 236
Modification date20220514
UniProtAcc


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Zfp236

GO:0000978

RNA polymerase II cis-regulatory region sequence-specific DNA binding

21873635

Function
Zfp236

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

21873635

Function
Zfp236

GO:0005634

nucleus

21873635

Component
Zfp236

GO:0006357

regulation of transcription by RNA polymerase II

21873635

Process

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Spatial pattern events for Zfp236

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Zfp236MouseKidneyIRI 340037979.91e-06
Zfp236MouseBrainrep_4 350277298.86e-08
Zfp236MouseIntestinerep_4 351497215.58e-06
Zfp236MouseLymphA1 01.32e-06

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_IRI_H&E
boxplot

boxplot
Brain_rep_4_H&E
boxplot

boxplot


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Spatial pattern pathway has Zfp236 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Zfp236GOBP_Carbohydrate_HomeostasisMouseSpinal cordL7CN45_C1 6.8e-08
Zfp236GOBP_Cellular_Glucose_HomeostasisMouseSpinal cordL7CN45_C1 3.9e-06
Zfp236GOBP_Cellular_HomeostasisMouseSpinal cordL7CN45_C1 5.7e-08
Zfp236GOBP_Cellular_Response_To_Carbohydrate_StimulusMouseSpinal cordL7CN45_C1 3.7e-06
Zfp236GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseSpinal cordL7CN45_C1 1.6e-07
Zfp236GOBP_Chemical_HomeostasisMouseSpinal cordL7CN45_C1 3.4e-09
Zfp236GOBP_Homeostatic_ProcessMouseSpinal cordL7CN45_C1 3.4e-09
Zfp236GOBP_Response_To_CarbohydrateMouseSpinal cordL7CN45_C1 1.2e-09
Zfp236GOBP_Response_To_MonosaccharideMouseSpinal cordL7CN45_C1 6.7e-07
Zfp236GOBP_Response_To_Oxygen_Containing_CompoundMouseSpinal cordL7CN45_C1 8.5e-07
Zfp236GOBP_Cellular_HomeostasisMouseBrainrep_71 6.9e-06
Zfp236GOBP_Chemical_HomeostasisMouseBrainrep_71 8.4e-05
Zfp236GOBP_Carbohydrate_HomeostasisMouseBrainrep_1 7.2e-09
Zfp236GOBP_Cellular_Glucose_HomeostasisMouseBrainrep_1 9.4e-21
Zfp236GOBP_Cellular_Response_To_Carbohydrate_StimulusMouseBrainrep_1 5.0e-17
Zfp236GOBP_Response_To_MonosaccharideMouseBrainrep_1 1.8e-15
Zfp236GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseBrainrep_3 8.2e-81
Zfp236GOBP_Response_To_Oxygen_Containing_CompoundMouseBrainrep_3 6.3e-92
Zfp236GOBP_Response_To_CarbohydrateMouseBrainrep_4 6.0e-07
Zfp236GOBP_Homeostatic_ProcessMouseBrainrep_7 2.5e-13
Zfp236GOBP_Response_To_MonosaccharideMouseEmbryorep_14 2.3e-08
Zfp236GOBP_Homeostatic_ProcessMouseEmbryorep_1 2.0e-30
Zfp236GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseEmbryorep_3 0.0e+00
Zfp236GOBP_Response_To_Oxygen_Containing_CompoundMouseEmbryorep_3 0.0e+00
Zfp236GOBP_Response_To_Oxygen_Containing_CompoundMouseKidneyNep 6.8e-28
Zfp236GOBP_Carbohydrate_HomeostasisMouseKidneyrep_2 3.5e-80
Zfp236GOBP_Cellular_Glucose_HomeostasisMouseKidneyrep_2 1.6e-67
Zfp236GOBP_Cellular_Response_To_Carbohydrate_StimulusMouseKidneyrep_2 5.8e-43
Zfp236GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseKidneyrep_2 4.5e-89
Zfp236GOBP_Homeostatic_ProcessMouseKidneyrep_2 2.2e-10
Zfp236GOBP_Response_To_CarbohydrateMouseKidneyrep_2 6.9e-74
Zfp236GOBP_Response_To_MonosaccharideMouseKidneyrep_2 8.2e-43
Zfp236GOBP_Response_To_Oxygen_Containing_CompoundMouseKidneyrep_26.6e-112
Zfp236GOBP_Cellular_Glucose_HomeostasisMouseLiverCN16-D2 8.3e-07
Zfp236GOBP_Response_To_CarbohydrateMouseLiverrep_23 6.8e-09
Zfp236GOBP_Response_To_MonosaccharideMouseLiverrep_23 1.3e-10
Zfp236GOBP_Carbohydrate_HomeostasisMouseLymphMS-1 1.3e-09
Zfp236GOBP_Cellular_Glucose_HomeostasisMouseLymphMS-1 8.5e-12
Zfp236GOBP_Cellular_HomeostasisMouseLymphMS-1 8.2e-11
Zfp236GOBP_Cellular_Response_To_Carbohydrate_StimulusMouseLymphMS-1 7.9e-12
Zfp236GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseLymphMS-1 7.5e-11
Zfp236GOBP_Chemical_HomeostasisMouseLymphMS-1 8.2e-11
Zfp236GOBP_Homeostatic_ProcessMouseLymphMS-1 2.3e-12
Zfp236GOBP_Response_To_CarbohydrateMouseLymphMS-1 3.0e-14
Zfp236GOBP_Response_To_MonosaccharideMouseLymphMS-1 2.2e-12
Zfp236GOBP_Response_To_Oxygen_Containing_CompoundMouseLymphMS-1 1.8e-09
Zfp236GOBP_Response_To_Oxygen_Containing_CompoundMouseLungrep_1 1.2e-19
Zfp236GOBP_Response_To_CarbohydrateMouseBrainrep_4 1.6e-11
Zfp236GOBP_Carbohydrate_HomeostasisMouseBrainHP_ad_rep7 3.7e-09
Zfp236GOBP_Cellular_Glucose_HomeostasisMouseBrainHP_ad_rep7 1.7e-09
Zfp236GOBP_Cellular_Response_To_Oxygen_Containing_CompoundMouseBrainHP_ad_rep7 2.6e-10
Zfp236GOBP_Response_To_Oxygen_Containing_CompoundMouseBrainHP_ad_rep7 4.2e-09
Zfp236GOBP_Cellular_HomeostasisMouseBrainHP_polb_rep9 1.2e-09
Zfp236GOBP_Chemical_HomeostasisMouseBrainHP_polb_rep9 9.6e-10
Zfp236GOBP_Homeostatic_ProcessMouseBrainHP_polb_rep9 6.4e-11
Zfp236GOBP_Response_To_CarbohydrateMouseBrainHP_polb_rep9 3.2e-07
Zfp236GOBP_Response_To_MonosaccharideMouseBrainHP_polb_rep9 4.5e-09

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Zfp236 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Zfp236 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Zfp236 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score
Zfp236LymphcontrolMature BPlagl2,Wasl,Gsk3b, etc.0.282
Zfp236KidneyIRIUrotheliumRnf34,Myd88,Pof1b, etc.0.252

check button Motif information.
boxplot
boxplot

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Related Drugs for Zfp236

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Zfp236

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource