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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Mkln1 (spascer ID:27418)

Gene summary for Mkln1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Mkln1
	Gene ID	27418
	Gene name	muskelin 1, intracellular mediator containing kelch motifs
	Synonyms	A130067F06Rik\|AU015903\|BB154892
	Cytomap	6\|6 A3.3
	Type of gene	protein-coding
	Description	muskelin
	Modification date	20220424
	UniProtAcc	O89050

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Mkln1	GO:0005737	cytoplasm	21873635	Component

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Spatial pattern events for Mkln1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Mkln1	Mouse	Embryo	1D	34210887	1.15e-11
Mkln1	Mouse	Intestine	rep_4	35149721	2.16e-06
Mkln1	Mouse	Lymph	A1	0	1.20e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)

Singel gene map

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Spatial pattern pathway has Mkln1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Mkln1	GOBP_Endocytosis	Mouse	Spinal cord	CN94_E1	8.2e-06
Mkln1	GOBP_Regulation_Of_Endocytosis	Mouse	Spinal cord	CN94_E1	7.5e-06
Mkln1	GOBP_Regulation_Of_Transport	Mouse	Spinal cord	CN94_E1	5.3e-07
Mkln1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Spinal cord	CN94_E1	5.3e-06
Mkln1	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Mkln1	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Mkln1	GOBP_Biological_Adhesion	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Mkln1	GOBP_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Mkln1	GOBP_Receptor_Mediated_Endocytosis	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Mkln1	GOBP_Receptor_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Mkln1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.1e-08
Mkln1	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Mkln1	GOBP_Regulation_Of_Cell_Shape	Mouse	Spinal cord	L7CN45_C1	2.7e-06
Mkln1	GOBP_Regulation_Of_Receptor_Mediated_Endocytosis	Mouse	Spinal cord	L7CN45_C1	1.2e-08
Mkln1	GOBP_Actin_Filament_Based_Process	Mouse	Spinal cord	L7CN47_C1	3.4e-06
Mkln1	GOBP_Receptor_Internalization	Mouse	Spinal cord	L7CN47_C1	5.4e-06
Mkln1	GOBP_Regulation_Of_Receptor_Internalization	Mouse	Spinal cord	L7CN47_C1	4.2e-07
Mkln1	GOBP_Cell_Substrate_Adhesion	Mouse	Spinal cord	L7CN97_E2	2.2e-06
Mkln1	GOBP_Actin_Filament_Based_Process	Mouse	Brain	rep_1	2.1e-24
Mkln1	GOBP_Cell_Morphogenesis	Mouse	Brain	rep_1	7.6e-08
Mkln1	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Mkln1	GOBP_Receptor_Internalization	Mouse	Brain	rep_1	2.6e-34
Mkln1	GOBP_Regulation_Of_Transport	Mouse	Brain	rep_1	3.9e-15
Mkln1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Brain	rep_1	5.0e-23
Mkln1	GOBP_Biological_Adhesion	Mouse	Brain	rep_3	4.3e-106
Mkln1	GOBP_Cell_Substrate_Adhesion	Mouse	Brain	rep_3	1.8e-27
Mkln1	GOBP_Endocytosis	Mouse	Brain	rep_3	2.6e-20
Mkln1	GOBP_Receptor_Mediated_Endocytosis	Mouse	Brain	rep_3	3.1e-52
Mkln1	GOBP_Receptor_Metabolic_Process	Mouse	Brain	rep_3	2.4e-72
Mkln1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	rep_3	3.2e-44
Mkln1	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Brain	rep_3	5.0e-45
Mkln1	GOBP_Regulation_Of_Cell_Shape	Mouse	Brain	rep_3	2.1e-19
Mkln1	GOBP_Regulation_Of_Endocytosis	Mouse	Brain	rep_3	1.9e-49
Mkln1	GOBP_Regulation_Of_Receptor_Mediated_Endocytosis	Mouse	Brain	rep_3	1.1e-46
Mkln1	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Brain	rep_7	1.8e-32
Mkln1	GOBP_Regulation_Of_Receptor_Internalization	Mouse	Embryo	rep_6	4.5e-11
Mkln1	GOBP_Regulation_Of_Receptor_Mediated_Endocytosis	Mouse	Embryo	rep_6	5.1e-08
Mkln1	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Embryo	rep_14	8.6e-16
Mkln1	GOBP_Regulation_Of_Cell_Shape	Mouse	Embryo	rep_14	5.1e-07
Mkln1	GOBP_Biological_Adhesion	Mouse	Embryo	rep_1	2.2e-19
Mkln1	GOBP_Cell_Matrix_Adhesion	Mouse	Embryo	rep_1	1.6e-47
Mkln1	GOBP_Cell_Substrate_Adhesion	Mouse	Embryo	rep_1	2.0e-34
Mkln1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Embryo	rep_1	3.8e-34
Mkln1	GOBP_Receptor_Mediated_Endocytosis	Mouse	Embryo	rep_2	1.2e-141
Mkln1	GOBP_Regulation_Of_Endocytosis	Mouse	Embryo	rep_2	2.4e-105
Mkln1	GOBP_Receptor_Internalization	Mouse	Embryo	rep_3	1.5e-61
Mkln1	GOBP_Regulation_Of_Receptor_Internalization	Mouse	Embryo	rep_3	1.2e-27
Mkln1	GOBP_Regulation_Of_Receptor_Mediated_Endocytosis	Mouse	Embryo	rep_3	1.2e-27
Mkln1	GOBP_Cell_Morphogenesis	Mouse	Embryo	rep_5	2.2e-13
Mkln1	GOBP_Cell_Morphogenesis	Mouse	Kidney	Nep	1.1e-16
Mkln1	GOBP_Endocytosis	Mouse	Kidney	Nep	8.3e-23
Mkln1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	Nep	1.3e-32
Mkln1	GOBP_Regulation_Of_Transport	Mouse	Kidney	Nep	2.6e-47
Mkln1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Kidney	Nep	2.7e-48
Mkln1	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Kidney	rep_2	2.1e-101
Mkln1	GOBP_Actin_Filament_Based_Process	Mouse	Kidney	rep_2	2.6e-107
Mkln1	GOBP_Biological_Adhesion	Mouse	Kidney	rep_2	1.3e-48
Mkln1	GOBP_Cell_Matrix_Adhesion	Mouse	Kidney	rep_2	2.0e-31
Mkln1	GOBP_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.7e-84
Mkln1	GOBP_Cell_Substrate_Adhesion	Mouse	Kidney	rep_2	4.0e-46
Mkln1	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Mkln1	GOBP_Endocytosis	Mouse	Kidney	rep_2	1.4e-132
Mkln1	GOBP_Receptor_Internalization	Mouse	Kidney	rep_2	1.1e-18
Mkln1	GOBP_Receptor_Mediated_Endocytosis	Mouse	Kidney	rep_2	4.7e-166
Mkln1	GOBP_Receptor_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-35
Mkln1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	rep_2	1.3e-133
Mkln1	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Kidney	rep_2	1.9e-85
Mkln1	GOBP_Regulation_Of_Cell_Shape	Mouse	Kidney	rep_2	3.0e-66
Mkln1	GOBP_Regulation_Of_Endocytosis	Mouse	Kidney	rep_2	5.5e-162
Mkln1	GOBP_Regulation_Of_Receptor_Mediated_Endocytosis	Mouse	Kidney	rep_2	4.0e-143
Mkln1	GOBP_Regulation_Of_Transport	Mouse	Kidney	rep_2	2.4e-58
Mkln1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Kidney	rep_2	8.7e-134
Mkln1	GOBP_Receptor_Metabolic_Process	Mouse	Liver	CN16-D2	2.2e-07
Mkln1	GOBP_Regulation_Of_Receptor_Mediated_Endocytosis	Mouse	Liver	CN73-C1	2.4e-07
Mkln1	GOBP_Regulation_Of_Transport	Mouse	Liver	CN73-C1	1.8e-07
Mkln1	GOBP_Biological_Adhesion	Mouse	Liver	rep_16	2.1e-07
Mkln1	GOBP_Cell_Matrix_Adhesion	Mouse	Liver	rep_16	2.7e-08
Mkln1	GOBP_Receptor_Metabolic_Process	Mouse	Liver	rep_16	3.8e-11
Mkln1	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Lymph	MS-1	1.7e-07
Mkln1	GOBP_Actin_Filament_Based_Process	Mouse	Lymph	MS-1	1.4e-10
Mkln1	GOBP_Biological_Adhesion	Mouse	Lymph	MS-1	8.0e-14
Mkln1	GOBP_Cell_Matrix_Adhesion	Mouse	Lymph	MS-1	3.5e-08
Mkln1	GOBP_Cell_Morphogenesis	Mouse	Lymph	MS-1	3.9e-13
Mkln1	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Mkln1	GOBP_Endocytosis	Mouse	Lymph	MS-1	1.8e-21
Mkln1	GOBP_Receptor_Internalization	Mouse	Lymph	MS-1	6.9e-09
Mkln1	GOBP_Receptor_Mediated_Endocytosis	Mouse	Lymph	MS-1	2.1e-11
Mkln1	GOBP_Receptor_Metabolic_Process	Mouse	Lymph	MS-1	1.5e-07
Mkln1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Lymph	MS-1	2.4e-16
Mkln1	GOBP_Regulation_Of_Cell_Morphogenesis	Mouse	Lymph	MS-1	2.2e-13
Mkln1	GOBP_Regulation_Of_Cell_Shape	Mouse	Lymph	MS-1	5.2e-14
Mkln1	GOBP_Regulation_Of_Endocytosis	Mouse	Lymph	MS-1	3.1e-08
Mkln1	GOBP_Regulation_Of_Receptor_Internalization	Mouse	Lymph	MS-1	9.2e-08
Mkln1	GOBP_Regulation_Of_Receptor_Mediated_Endocytosis	Mouse	Lymph	MS-1	3.7e-08
Mkln1	GOBP_Regulation_Of_Transport	Mouse	Lymph	MS-1	1.4e-12
Mkln1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Lymph	MS-1	1.8e-09
Mkln1	GOBP_Biological_Adhesion	Mouse	Lung	rep_1	3.0e-22
Mkln1	GOBP_Cell_Matrix_Adhesion	Mouse	Brain	rep_4	7.1e-07
Mkln1	GOBP_Receptor_Metabolic_Process	Mouse	Brain	rep_4	1.2e-21
Mkln1	GOBP_Regulation_Of_Endocytosis	Mouse	Brain	rep_4	1.0e-12
Mkln1	GOBP_Regulation_Of_Receptor_Internalization	Mouse	Brain	rep_4	1.0e-07
Mkln1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Brain	rep_4	5.3e-09
Mkln1	GOBP_Actin_Cytoskeleton_Reorganization	Mouse	Brain	HP_ad_rep7	2.6e-08
Mkln1	GOBP_Cell_Matrix_Adhesion	Mouse	Brain	HP_ad_rep7	5.6e-10
Mkln1	GOBP_Cell_Morphogenesis	Mouse	Brain	HP_ad_rep7	8.4e-10
Mkln1	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Mkln1	GOBP_Receptor_Internalization	Mouse	Brain	HP_ad_rep7	3.1e-07
Mkln1	GOBP_Receptor_Mediated_Endocytosis	Mouse	Brain	HP_ad_rep7	1.4e-08
Mkln1	GOBP_Receptor_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-07
Mkln1	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	HP_ad_rep7	3.3e-08
Mkln1	GOBP_Regulation_Of_Receptor_Mediated_Endocytosis	Mouse	Brain	HP_ad_rep7	5.5e-07
Mkln1	GOBP_Regulation_Of_Transport	Mouse	Brain	HP_ad_rep7	9.2e-09
Mkln1	GOBP_Actin_Filament_Based_Process	Mouse	Brain	HP_polb_rep9	3.0e-07
Mkln1	GOBP_Biological_Adhesion	Mouse	Brain	HP_polb_rep9	1.5e-07
Mkln1	GOBP_Cell_Substrate_Adhesion	Mouse	Brain	HP_polb_rep9	3.3e-07
Mkln1	GOBP_Endocytosis	Mouse	Brain	HP_polb_rep9	3.2e-09
Mkln1	GOBP_Regulation_Of_Cell_Shape	Mouse	Brain	HP_polb_rep9	2.9e-08
Mkln1	GOBP_Regulation_Of_Endocytosis	Mouse	Brain	HP_polb_rep9	4.2e-09
Mkln1	GOBP_Regulation_Of_Receptor_Internalization	Mouse	Brain	HP_polb_rep9	9.4e-09
Mkln1	GOBP_Regulation_Of_Vesicle_Mediated_Transport	Mouse	Brain	HP_polb_rep9	9.9e-09

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Mkln1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Mkln1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Mkln1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Mkln1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Mkln1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source