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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Gins2 (spascer ID:272551)

Gene summary for Gins2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Gins2
	Gene ID	272551
	Gene name	GINS complex subunit 2 (Psf2 homolog)
	Synonyms	2210013I18Rik\|4833427B12Rik\|AI323585\|Pfs2
	Cytomap	8\|8 E1
	Type of gene	protein-coding
	Description	DNA replication complex GINS protein PSF2
	Modification date	20220424
	UniProtAcc	Q9D600

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Gins2	GO:0000727	double-strand break repair via break-induced replication	21873635	Process
Gins2	GO:0000811	GINS complex	21873635	Component

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Spatial pattern events for Gins2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Gins2	Mouse	Kidney	rep_5	34853151	5.45e-15
Gins2	Mouse	Testicle	rep_5	34731600	8.22e-07
Gins2	Mouse	Lymph	A1	0	7.87e-11
Gins2	Mouse	Lymph	B1	0	3.66e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_5_H&E

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Spatial pattern pathway has Gins2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Gins2	GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication	Mouse	Spinal cord	CN90_C1	3.8e-06
Gins2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Spinal cord	CN94_E1	8.0e-06
Gins2	GOBP_Dna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	2.7e-06
Gins2	GOBP_Recombinational_Repair	Mouse	Spinal cord	CN94_E1	8.5e-06
Gins2	GOBP_Dna_Strand_Elongation_Involved_In_Dna_Replication	Mouse	Spinal cord	L7CN30_C2	3.2e-06
Gins2	GOBP_Dna_Recombination	Mouse	Spinal cord	L7CN45_C1	5.6e-07
Gins2	GOBP_Dna_Repair	Mouse	Spinal cord	L7CN45_C1	9.4e-06
Gins2	GOBP_Dna_Replication	Mouse	Spinal cord	L7CN45_C1	2.8e-07
Gins2	GOBP_Dna_Strand_Elongation	Mouse	Spinal cord	L7CN45_C1	3.7e-06
Gins2	GOBP_Double_Strand_Break_Repair	Mouse	Spinal cord	L7CN45_C1	5.4e-06
Gins2	GOBP_Dna_Dependent_Dna_Replication	Mouse	Spinal cord	L7CN47_C1	6.6e-06
Gins2	GOBP_Dna_Replication	Mouse	Brain	rep_27	6.4e-06
Gins2	GOBP_Dna_Strand_Elongation	Mouse	Brain	rep_41	1.1e-05
Gins2	GOBP_Dna_Dependent_Dna_Replication	Mouse	Brain	rep_1	1.5e-17
Gins2	GOBP_Dna_Metabolic_Process	Mouse	Brain	rep_1	1.1e-07
Gins2	GOBP_Dna_Recombination	Mouse	Brain	rep_1	6.8e-13
Gins2	GOBP_Dna_Replication	Mouse	Brain	rep_1	4.3e-10
Gins2	GOBP_Dna_Strand_Elongation	Mouse	Brain	rep_1	5.6e-11
Gins2	GOBP_Double_Strand_Break_Repair	Mouse	Brain	rep_1	5.6e-13
Gins2	GOBP_Recombinational_Repair	Mouse	Brain	rep_1	5.8e-08
Gins2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	rep_3	5.0e-192
Gins2	GOBP_Dna_Repair	Mouse	Brain	rep_3	4.0e-216
Gins2	GOBP_Dna_Strand_Elongation_Involved_In_Dna_Replication	Mouse	Brain	rep_3	1.8e-40
Gins2	GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication	Mouse	Brain	rep_5	5.3e-09
Gins2	GOBP_Dna_Strand_Elongation_Involved_In_Dna_Replication	Mouse	Embryo	rep_14	3.6e-17
Gins2	GOBP_Double_Strand_Break_Repair	Mouse	Embryo	rep_14	1.4e-07
Gins2	GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication	Mouse	Embryo	rep_14	1.6e-37
Gins2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Embryo	rep_2	1.4e-08
Gins2	GOBP_Dna_Metabolic_Process	Mouse	Embryo	rep_2	7.2e-216
Gins2	GOBP_Dna_Recombination	Mouse	Embryo	rep_2	0.0e+00
Gins2	GOBP_Dna_Repair	Mouse	Embryo	rep_2	1.6e-282
Gins2	GOBP_Double_Strand_Break_Repair	Mouse	Embryo	rep_2	4.2e-15
Gins2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Kidney	rep_2	5.5e-146
Gins2	GOBP_Dna_Dependent_Dna_Replication	Mouse	Kidney	rep_2	1.1e-109
Gins2	GOBP_Dna_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-12
Gins2	GOBP_Dna_Recombination	Mouse	Kidney	rep_2	2.7e-14
Gins2	GOBP_Dna_Repair	Mouse	Kidney	rep_2	5.5e-70
Gins2	GOBP_Dna_Replication	Mouse	Kidney	rep_2	5.9e-43
Gins2	GOBP_Dna_Strand_Elongation	Mouse	Kidney	rep_2	2.0e-61
Gins2	GOBP_Dna_Strand_Elongation_Involved_In_Dna_Replication	Mouse	Kidney	rep_2	2.3e-26
Gins2	GOBP_Double_Strand_Break_Repair	Mouse	Kidney	rep_2	1.5e-20
Gins2	GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication	Mouse	Kidney	rep_2	3.5e-28
Gins2	GOBP_Dna_Dependent_Dna_Replication	Mouse	Liver	CN16-D2	3.1e-08
Gins2	GOBP_Dna_Metabolic_Process	Mouse	Liver	CN16-D2	2.6e-07
Gins2	GOBP_Dna_Strand_Elongation_Involved_In_Dna_Replication	Mouse	Liver	rep_15	1.1e-13
Gins2	GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication	Mouse	Liver	rep_15	7.8e-15
Gins2	GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication	Mouse	Intestine	rep_3	1.1e-13
Gins2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Lymph	MS-1	8.5e-13
Gins2	GOBP_Dna_Metabolic_Process	Mouse	Lymph	MS-1	6.8e-10
Gins2	GOBP_Dna_Dependent_Dna_Replication	Mouse	Lymph	PBS	2.2e-07
Gins2	GOBP_Double_Strand_Break_Repair_Via_Break_Induced_Replication	Mouse	Brain	HP_ad_rep3	1.5e-15
Gins2	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	HP_ad_rep7	6.8e-10
Gins2	GOBP_Dna_Dependent_Dna_Replication	Mouse	Brain	HP_ad_rep7	1.6e-15
Gins2	GOBP_Dna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-11
Gins2	GOBP_Dna_Recombination	Mouse	Brain	HP_ad_rep7	1.4e-08
Gins2	GOBP_Dna_Repair	Mouse	Brain	HP_ad_rep7	2.4e-12
Gins2	GOBP_Dna_Replication	Mouse	Brain	HP_ad_rep7	1.1e-10
Gins2	GOBP_Dna_Strand_Elongation	Mouse	Brain	HP_ad_rep7	4.9e-11
Gins2	GOBP_Dna_Strand_Elongation_Involved_In_Dna_Replication	Mouse	Brain	HP_ad_rep7	3.6e-13
Gins2	GOBP_Double_Strand_Break_Repair	Mouse	Brain	HP_ad_rep7	2.7e-09
Gins2	GOBP_Recombinational_Repair	Mouse	Brain	HP_ad_rep7	8.2e-08

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Gins2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Gins2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Gins2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Gins2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Gins2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Gins2	C0010606	Adenoid Cystic Carcinoma	1	CTD_human
Gins2	C0036095	Salivary Gland Neoplasms	1	CTD_human
Gins2	C0220636	Malignant neoplasm of salivary gland	1	CTD_human