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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Mthfd1l (spascer ID:270685)

Gene summary for Mthfd1l

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Mthfd1l
	Gene ID	270685
	Gene name	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
	Synonyms	2410004L15Rik\|AI647056\|Fthfsdc1
	Cytomap	10\|10 A1
	Type of gene	protein-coding
	Description	monofunctional C1-tetrahydrofolate synthase, mitochondrialformyltetrahydrofolate synthetase domain containing 1
	Modification date	20220424
	UniProtAcc	Q3V3R1

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Mthfd1l	GO:0005739	mitochondrion	21873635	Component
Mthfd1l	GO:0005829	cytosol	21873635	Component
Mthfd1l	GO:0035999	tetrahydrofolate interconversion	21873635	Process

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Spatial pattern events for Mthfd1l

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Mthfd1l	Mouse	Embryo	rep_4	33188776	8.48e-10
Mthfd1l	Mouse	Embryo	rep_13	33188776	6.75e-08
Mthfd1l	Mouse	Kidney	IRI	34003797	2.89e-14
Mthfd1l	Mouse	Brain	rep_1	33469025	3.25e-11
Mthfd1l	Mouse	Brain	rep_1	35027729	1.66e-15
Mthfd1l	Mouse	Brain	rep_2	35027729	1.57e-15
Mthfd1l	Mouse	Brain	rep_3	35027729	1.32e-15
Mthfd1l	Mouse	Brain	rep_4	35027729	1.76e-15
Mthfd1l	Mouse	Brain	rep_5	35027729	1.46e-15
Mthfd1l	Mouse	Lymph	B1	0	3.16e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_IRI_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Mthfd1l envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Mthfd1l	GOBP_Animal_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	6.6e-06
Mthfd1l	GOBP_Cranial_Skeletal_System_Development	Mouse	Spinal cord	CN94_E1	2.5e-06
Mthfd1l	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	7.7e-07
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	CN94_E1	1.7e-06
Mthfd1l	GOBP_Skeletal_System_Development	Mouse	Spinal cord	CN94_E1	5.6e-06
Mthfd1l	GOBP_Folic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN01_D2	8.9e-06
Mthfd1l	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN41_C2	8.8e-07
Mthfd1l	GOBP_Tetrahydrofolate_Interconversion	Mouse	Spinal cord	L7CN41_C2	6.9e-06
Mthfd1l	GOBP_Pteridine_Containing_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN44_C1	2.7e-06
Mthfd1l	GOBP_Formate_Metabolic_Process	Mouse	Spinal cord	L7CN44_D1	2.6e-06
Mthfd1l	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Mthfd1l	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.5e-06
Mthfd1l	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Mthfd1l	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Spinal cord	L7CN45_C1	3.9e-07
Mthfd1l	GOBP_Embryonic_Cranial_Skeleton_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.7e-08
Mthfd1l	GOBP_Embryonic_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Mthfd1l	GOBP_Embryonic_Organ_Development	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Mthfd1l	GOBP_Epithelial_Tube_Formation	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Mthfd1l	GOBP_Epithelial_Tube_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	2.1e-08
Mthfd1l	GOBP_Epithelium_Development	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Mthfd1l	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.2e-09
Mthfd1l	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Spinal cord	L7CN45_C1	8.3e-08
Mthfd1l	GOBP_Morphogenesis_Of_Embryonic_Epithelium	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Mthfd1l	GOBP_Neural_Tube_Development	Mouse	Spinal cord	L7CN45_C1	6.8e-10
Mthfd1l	GOBP_Neural_Tube_Formation	Mouse	Spinal cord	L7CN45_C1	1.2e-09
Mthfd1l	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.8e-07
Mthfd1l	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Mthfd1l	GOBP_Skeletal_System_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	2.2e-08
Mthfd1l	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Mthfd1l	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Mthfd1l	GOBP_Tissue_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.3e-08
Mthfd1l	GOBP_Tube_Development	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Mthfd1l	GOBP_Tube_Formation	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Mthfd1l	GOBP_Tube_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Mthfd1l	GOBP_Vitamin_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Mthfd1l	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.2e-07
Mthfd1l	GOBP_10_Formyltetrahydrofolate_Metabolic_Process	Mouse	Spinal cord	L7CN45_E1	3.9e-06
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Spinal cord	L7CN45_E1	2.3e-06
Mthfd1l	GOBP_Embryonic_Viscerocranium_Morphogenesis	Mouse	Spinal cord	L7CN45_E1	1.4e-08
Mthfd1l	GOBP_Tetrahydrofolate_Metabolic_Process	Mouse	Spinal cord	L7CN45_E1	7.0e-08
Mthfd1l	GOBP_Embryonic_Skeletal_System_Development	Mouse	Spinal cord	L7CN47_C1	3.7e-07
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Biosynthetic_Process	Mouse	Spinal cord	L7CN47_D1	7.3e-06
Mthfd1l	GOBP_Tetrahydrofolate_Biosynthetic_Process	Mouse	Spinal cord	L7CN47_D1	4.2e-08
Mthfd1l	GOBP_Dicarboxylic_Acid_Biosynthetic_Process	Mouse	Spinal cord	L7CN60_D1	8.2e-06
Mthfd1l	GOBP_10_Formyltetrahydrofolate_Metabolic_Process	Mouse	Brain	rep_9	1.2e-08
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Brain	rep_9	5.8e-06
Mthfd1l	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_11	1.9e-05
Mthfd1l	GOBP_Formate_Metabolic_Process	Mouse	Brain	rep_15	5.8e-05
Mthfd1l	GOBP_Folic_Acid_Metabolic_Process	Mouse	Brain	rep_19	1.6e-07
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_21	3.8e-05
Mthfd1l	GOBP_Vitamin_Metabolic_Process	Mouse	Brain	rep_21	6.6e-05
Mthfd1l	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_27	2.0e-06
Mthfd1l	GOBP_Tetrahydrofolate_Interconversion	Mouse	Brain	rep_27	1.5e-05
Mthfd1l	GOBP_Neural_Tube_Formation	Mouse	Brain	rep_37	1.9e-05
Mthfd1l	GOBP_Epithelial_Tube_Formation	Mouse	Brain	rep_41	2.9e-05
Mthfd1l	GOBP_Morphogenesis_Of_Embryonic_Epithelium	Mouse	Brain	rep_41	4.9e-06
Mthfd1l	GOBP_Tetrahydrofolate_Metabolic_Process	Mouse	Brain	rep_41	1.6e-09
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Biosynthetic_Process	Mouse	Brain	rep_42	3.6e-07
Mthfd1l	GOBP_Tetrahydrofolate_Biosynthetic_Process	Mouse	Brain	rep_42	6.3e-05
Mthfd1l	GOBP_Embryonic_Viscerocranium_Morphogenesis	Mouse	Brain	rep_70	4.3e-07
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Biosynthetic_Process	Mouse	Brain	rep_71	5.3e-05
Mthfd1l	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_71	2.6e-07
Mthfd1l	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_71	8.1e-05
Mthfd1l	GOBP_One_Carbon_Metabolic_Process	Mouse	Brain	rep_71	3.8e-05
Mthfd1l	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	rep_71	7.6e-05
Mthfd1l	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	rep_1	1.0e-08
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Biosynthetic_Process	Mouse	Brain	rep_1	4.0e-12
Mthfd1l	GOBP_10_Formyltetrahydrofolate_Metabolic_Process	Mouse	Brain	rep_3	7.7e-106
Mthfd1l	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	rep_3	5.3e-58
Mthfd1l	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_3	5.4e-57
Mthfd1l	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.6e-109
Mthfd1l	GOBP_Cranial_Skeletal_System_Development	Mouse	Brain	rep_3	7.3e-113
Mthfd1l	GOBP_Dicarboxylic_Acid_Biosynthetic_Process	Mouse	Brain	rep_3	4.1e-145
Mthfd1l	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.2e-146
Mthfd1l	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
Mthfd1l	GOBP_Embryonic_Cranial_Skeleton_Morphogenesis	Mouse	Brain	rep_3	2.1e-140
Mthfd1l	GOBP_Embryonic_Morphogenesis	Mouse	Brain	rep_3	5.0e-165
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Brain	rep_3	6.0e-42
Mthfd1l	GOBP_Embryonic_Organ_Development	Mouse	Brain	rep_3	4.3e-190
Mthfd1l	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_3	1.5e-168
Mthfd1l	GOBP_Embryonic_Skeletal_System_Development	Mouse	Brain	rep_3	1.0e-111
Mthfd1l	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Brain	rep_3	1.2e-119
Mthfd1l	GOBP_Embryonic_Viscerocranium_Morphogenesis	Mouse	Brain	rep_3	1.4e-89
Mthfd1l	GOBP_Epithelial_Tube_Formation	Mouse	Brain	rep_3	2.5e-225
Mthfd1l	GOBP_Epithelial_Tube_Morphogenesis	Mouse	Brain	rep_3	1.0e-204
Mthfd1l	GOBP_Epithelium_Development	Mouse	Brain	rep_3	8.3e-102
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_3	2.3e-50
Mthfd1l	GOBP_Folic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.8e-14
Mthfd1l	GOBP_Formate_Metabolic_Process	Mouse	Brain	rep_3	2.5e-21
Mthfd1l	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_3	3.2e-119
Mthfd1l	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Brain	rep_3	2.2e-135
Mthfd1l	GOBP_Morphogenesis_Of_Embryonic_Epithelium	Mouse	Brain	rep_3	2.9e-205
Mthfd1l	GOBP_Neural_Tube_Development	Mouse	Brain	rep_3	2.8e-187
Mthfd1l	GOBP_Neural_Tube_Formation	Mouse	Brain	rep_3	5.4e-223
Mthfd1l	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	rep_3	2.0e-17
Mthfd1l	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Mthfd1l	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Mthfd1l	GOBP_Skeletal_System_Development	Mouse	Brain	rep_3	3.3e-190
Mthfd1l	GOBP_Skeletal_System_Morphogenesis	Mouse	Brain	rep_3	7.3e-51
Mthfd1l	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Mthfd1l	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Mthfd1l	GOBP_Tetrahydrofolate_Biosynthetic_Process	Mouse	Brain	rep_3	7.6e-104
Mthfd1l	GOBP_Tetrahydrofolate_Interconversion	Mouse	Brain	rep_3	1.5e-83
Mthfd1l	GOBP_Tetrahydrofolate_Metabolic_Process	Mouse	Brain	rep_3	1.2e-108
Mthfd1l	GOBP_Tissue_Morphogenesis	Mouse	Brain	rep_3	4.8e-136
Mthfd1l	GOBP_Tube_Development	Mouse	Brain	rep_3	9.0e-136
Mthfd1l	GOBP_Tube_Formation	Mouse	Brain	rep_3	5.4e-189
Mthfd1l	GOBP_Tube_Morphogenesis	Mouse	Brain	rep_3	4.7e-120
Mthfd1l	GOBP_Vitamin_Metabolic_Process	Mouse	Brain	rep_3	2.6e-174
Mthfd1l	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Brain	rep_3	5.9e-186
Mthfd1l	GOBP_Dicarboxylic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_6	8.7e-20
Mthfd1l	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_6	7.1e-08
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Biosynthetic_Process	Mouse	Embryo	rep_6	6.8e-07
Mthfd1l	GOBP_Pteridine_Containing_Compound_Biosynthetic_Process	Mouse	Embryo	rep_6	7.8e-08
Mthfd1l	GOBP_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_6	3.8e-12
Mthfd1l	GOBP_Tetrahydrofolate_Interconversion	Mouse	Embryo	rep_6	4.1e-16
Mthfd1l	GOBP_Vitamin_Metabolic_Process	Mouse	Embryo	rep_6	1.0e-11
Mthfd1l	GOBP_10_Formyltetrahydrofolate_Metabolic_Process	Mouse	Embryo	rep_14	7.7e-18
Mthfd1l	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_14	1.7e-13
Mthfd1l	GOBP_Cranial_Skeletal_System_Development	Mouse	Embryo	rep_14	5.2e-63
Mthfd1l	GOBP_Embryonic_Cranial_Skeleton_Morphogenesis	Mouse	Embryo	rep_14	4.3e-57
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Embryo	rep_14	6.9e-23
Mthfd1l	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Embryo	rep_14	2.2e-13
Mthfd1l	GOBP_Embryonic_Skeletal_System_Development	Mouse	Embryo	rep_14	5.5e-53
Mthfd1l	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_14	2.3e-45
Mthfd1l	GOBP_Embryonic_Viscerocranium_Morphogenesis	Mouse	Embryo	rep_14	1.3e-25
Mthfd1l	GOBP_Epithelial_Tube_Formation	Mouse	Embryo	rep_14	6.5e-08
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_14	2.8e-44
Mthfd1l	GOBP_Folic_Acid_Metabolic_Process	Mouse	Embryo	rep_14	1.6e-46
Mthfd1l	GOBP_Formate_Metabolic_Process	Mouse	Embryo	rep_14	5.8e-24
Mthfd1l	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_14	7.3e-13
Mthfd1l	GOBP_One_Carbon_Metabolic_Process	Mouse	Embryo	rep_14	7.3e-52
Mthfd1l	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_14	7.1e-24
Mthfd1l	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Mthfd1l	GOBP_Pteridine_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_14	5.7e-37
Mthfd1l	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Mthfd1l	GOBP_Tetrahydrofolate_Biosynthetic_Process	Mouse	Embryo	rep_14	1.0e-43
Mthfd1l	GOBP_Tetrahydrofolate_Metabolic_Process	Mouse	Embryo	rep_14	6.5e-58
Mthfd1l	GOBP_Tube_Formation	Mouse	Embryo	rep_14	4.7e-07
Mthfd1l	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Embryo	rep_14	7.1e-79
Mthfd1l	GOBP_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_1	1.7e-10
Mthfd1l	GOBP_Epithelium_Development	Mouse	Embryo	rep_1	1.7e-09
Mthfd1l	GOBP_Neural_Tube_Development	Mouse	Embryo	rep_1	3.1e-09
Mthfd1l	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Mthfd1l	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Mthfd1l	GOBP_Cranial_Skeletal_System_Development	Mouse	Embryo	rep_3	0.0e+00
Mthfd1l	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
Mthfd1l	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Embryo	rep_3	0.0e+00
Mthfd1l	GOBP_Embryonic_Cranial_Skeleton_Morphogenesis	Mouse	Embryo	rep_3	6.1e-174
Mthfd1l	GOBP_Embryonic_Skeletal_System_Development	Mouse	Embryo	rep_3	4.4e-129
Mthfd1l	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_3	0.0e+00
Mthfd1l	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Embryo	rep_3	2.1e-14
Mthfd1l	GOBP_Morphogenesis_Of_Embryonic_Epithelium	Mouse	Embryo	rep_3	5.9e-125
Mthfd1l	GOBP_Neural_Tube_Formation	Mouse	Embryo	rep_3	1.4e-11
Mthfd1l	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Mthfd1l	GOBP_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_3	0.0e+00
Mthfd1l	GOBP_Tube_Formation	Mouse	Embryo	rep_3	1.2e-24
Mthfd1l	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_4	0.0e+00
Mthfd1l	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_4	1.5e-14
Mthfd1l	GOBP_Vitamin_Metabolic_Process	Mouse	Embryo	rep_4	6.0e-12
Mthfd1l	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Embryo	rep_6	3.8e-28
Mthfd1l	GOBP_Skeletal_System_Development	Mouse	Embryo	rep_6	3.1e-59
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Kidney	IRI	1.8e-22
Mthfd1l	GOBP_Tetrahydrofolate_Interconversion	Mouse	Kidney	IRI	3.1e-17
Mthfd1l	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Mthfd1l	GOBP_Tube_Development	Mouse	Kidney	Nep	5.6e-37
Mthfd1l	GOBP_Tube_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Mthfd1l	GOBP_10_Formyltetrahydrofolate_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-14
Mthfd1l	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	rep_2	5.6e-148
Mthfd1l	GOBP_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	4.2e-71
Mthfd1l	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	6.2e-36
Mthfd1l	GOBP_Cranial_Skeletal_System_Development	Mouse	Kidney	rep_2	2.5e-28
Mthfd1l	GOBP_Dicarboxylic_Acid_Biosynthetic_Process	Mouse	Kidney	rep_2	1.9e-105
Mthfd1l	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	8.2e-31
Mthfd1l	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
Mthfd1l	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Kidney	rep_2	9.8e-28
Mthfd1l	GOBP_Embryonic_Cranial_Skeleton_Morphogenesis	Mouse	Kidney	rep_2	7.7e-15
Mthfd1l	GOBP_Embryonic_Morphogenesis	Mouse	Kidney	rep_2	7.3e-66
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Kidney	rep_2	2.2e-16
Mthfd1l	GOBP_Embryonic_Organ_Development	Mouse	Kidney	rep_2	1.3e-60
Mthfd1l	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Kidney	rep_2	3.0e-55
Mthfd1l	GOBP_Embryonic_Skeletal_System_Development	Mouse	Kidney	rep_2	2.0e-38
Mthfd1l	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Kidney	rep_2	1.6e-37
Mthfd1l	GOBP_Epithelial_Tube_Formation	Mouse	Kidney	rep_2	2.6e-29
Mthfd1l	GOBP_Epithelial_Tube_Morphogenesis	Mouse	Kidney	rep_2	2.7e-56
Mthfd1l	GOBP_Epithelium_Development	Mouse	Kidney	rep_2	3.5e-92
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	1.9e-84
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	6.7e-84
Mthfd1l	GOBP_Folic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	4.4e-174
Mthfd1l	GOBP_Formate_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-29
Mthfd1l	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	4.4e-73
Mthfd1l	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Kidney	rep_2	8.3e-27
Mthfd1l	GOBP_Morphogenesis_Of_Embryonic_Epithelium	Mouse	Kidney	rep_2	5.6e-31
Mthfd1l	GOBP_Neural_Tube_Development	Mouse	Kidney	rep_2	4.7e-41
Mthfd1l	GOBP_Neural_Tube_Formation	Mouse	Kidney	rep_2	9.4e-45
Mthfd1l	GOBP_One_Carbon_Metabolic_Process	Mouse	Kidney	rep_2	8.9e-161
Mthfd1l	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Kidney	rep_2	7.1e-54
Mthfd1l	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Mthfd1l	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Mthfd1l	GOBP_Pteridine_Containing_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	3.6e-74
Mthfd1l	GOBP_Pteridine_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	3.6e-93
Mthfd1l	GOBP_Skeletal_System_Development	Mouse	Kidney	rep_2	7.5e-46
Mthfd1l	GOBP_Skeletal_System_Morphogenesis	Mouse	Kidney	rep_2	1.2e-20
Mthfd1l	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Mthfd1l	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Mthfd1l	GOBP_Tetrahydrofolate_Biosynthetic_Process	Mouse	Kidney	rep_2	5.9e-86
Mthfd1l	GOBP_Tetrahydrofolate_Interconversion	Mouse	Kidney	rep_2	1.3e-53
Mthfd1l	GOBP_Tetrahydrofolate_Metabolic_Process	Mouse	Kidney	rep_2	6.1e-63
Mthfd1l	GOBP_Tissue_Morphogenesis	Mouse	Kidney	rep_2	2.3e-21
Mthfd1l	GOBP_Tube_Development	Mouse	Kidney	rep_2	1.2e-129
Mthfd1l	GOBP_Tube_Formation	Mouse	Kidney	rep_2	1.8e-40
Mthfd1l	GOBP_Tube_Morphogenesis	Mouse	Kidney	rep_2	2.1e-134
Mthfd1l	GOBP_Vitamin_Metabolic_Process	Mouse	Kidney	rep_2	6.7e-44
Mthfd1l	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Kidney	rep_2	6.8e-65
Mthfd1l	GOBP_Cranial_Skeletal_System_Development	Mouse	Liver	CN16-D2	1.9e-08
Mthfd1l	GOBP_Dicarboxylic_Acid_Biosynthetic_Process	Mouse	Liver	CN16-D2	1.4e-09
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Liver	CN16-D2	7.2e-10
Mthfd1l	GOBP_Tetrahydrofolate_Biosynthetic_Process	Mouse	Liver	CN16-D2	5.6e-07
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Biosynthetic_Process	Mouse	Liver	CN16-E1	5.7e-07
Mthfd1l	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Liver	CN16-E1	7.0e-07
Mthfd1l	GOBP_Epithelial_Tube_Formation	Mouse	Liver	CN16-E1	2.1e-08
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Biosynthetic_Process	Mouse	Liver	CN16-E1	8.2e-07
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Metabolic_Process	Mouse	Liver	CN16-E1	1.1e-08
Mthfd1l	GOBP_Morphogenesis_Of_Embryonic_Epithelium	Mouse	Liver	CN16-E1	5.0e-09
Mthfd1l	GOBP_One_Carbon_Metabolic_Process	Mouse	Liver	CN16-E1	4.4e-30
Mthfd1l	GOBP_Tetrahydrofolate_Metabolic_Process	Mouse	Liver	CN16-E1	5.4e-12
Mthfd1l	GOBP_Neural_Tube_Development	Mouse	Liver	CN65-C1	1.4e-07
Mthfd1l	GOBP_10_Formyltetrahydrofolate_Metabolic_Process	Mouse	Liver	CN65-D2	9.4e-09
Mthfd1l	GOBP_Skeletal_System_Development	Mouse	Liver	CN73-C1	9.4e-07
Mthfd1l	GOBP_10_Formyltetrahydrofolate_Metabolic_Process	Mouse	Liver	rep_15	1.9e-07
Mthfd1l	GOBP_Cranial_Skeletal_System_Development	Mouse	Liver	rep_15	1.4e-09
Mthfd1l	GOBP_Embryonic_Cranial_Skeleton_Morphogenesis	Mouse	Liver	rep_15	2.8e-21
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Liver	rep_15	2.8e-12
Mthfd1l	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Liver	rep_15	1.5e-24
Mthfd1l	GOBP_Embryonic_Viscerocranium_Morphogenesis	Mouse	Liver	rep_15	1.7e-23
Mthfd1l	GOBP_Epithelial_Tube_Formation	Mouse	Liver	rep_16	8.6e-11
Mthfd1l	GOBP_Neural_Tube_Development	Mouse	Liver	rep_16	3.2e-09
Mthfd1l	GOBP_Tube_Formation	Mouse	Liver	rep_16	6.4e-09
Mthfd1l	GOBP_Formate_Metabolic_Process	Mouse	Liver	rep_20	1.1e-17
Mthfd1l	GOBP_10_Formyltetrahydrofolate_Metabolic_Process	Mouse	Brain	rep_1	1.9e-11
Mthfd1l	GOBP_Embryonic_Viscerocranium_Morphogenesis	Mouse	Brain	rep_1	6.5e-08
Mthfd1l	GOBP_Tetrahydrofolate_Biosynthetic_Process	Mouse	Brain	rep_1	1.3e-08
Mthfd1l	GOBP_One_Carbon_Metabolic_Process	Mouse	Intestine	rep_2	8.4e-138
Mthfd1l	GOBP_Pteridine_Containing_Compound_Biosynthetic_Process	Mouse	Intestine	rep_3	5.3e-17
Mthfd1l	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Lymph	MS-1	6.4e-13
Mthfd1l	GOBP_Animal_Organ_Morphogenesis	Mouse	Lymph	MS-1	4.4e-09
Mthfd1l	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Biosynthetic_Process	Mouse	Lymph	MS-1	3.3e-10
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.7e-15
Mthfd1l	GOBP_Cranial_Skeletal_System_Development	Mouse	Lymph	MS-1	2.4e-13
Mthfd1l	GOBP_Dicarboxylic_Acid_Biosynthetic_Process	Mouse	Lymph	MS-1	1.3e-12
Mthfd1l	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
Mthfd1l	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Lymph	MS-1	4.0e-11
Mthfd1l	GOBP_Embryonic_Cranial_Skeleton_Morphogenesis	Mouse	Lymph	MS-1	1.7e-15
Mthfd1l	GOBP_Embryonic_Morphogenesis	Mouse	Lymph	MS-1	5.6e-07
Mthfd1l	GOBP_Embryonic_Organ_Development	Mouse	Lymph	MS-1	1.1e-11
Mthfd1l	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Lymph	MS-1	1.4e-11
Mthfd1l	GOBP_Embryonic_Skeletal_System_Development	Mouse	Lymph	MS-1	5.9e-22
Mthfd1l	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Lymph	MS-1	7.9e-14
Mthfd1l	GOBP_Epithelial_Tube_Formation	Mouse	Lymph	MS-1	6.1e-10
Mthfd1l	GOBP_Epithelial_Tube_Morphogenesis	Mouse	Lymph	MS-1	1.5e-11
Mthfd1l	GOBP_Epithelium_Development	Mouse	Lymph	MS-1	8.5e-09
Mthfd1l	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Mthfd1l	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Lymph	MS-1	4.1e-10
Mthfd1l	GOBP_Morphogenesis_Of_Embryonic_Epithelium	Mouse	Lymph	MS-1	7.3e-13
Mthfd1l	GOBP_Neural_Tube_Development	Mouse	Lymph	MS-1	3.4e-10
Mthfd1l	GOBP_Neural_Tube_Formation	Mouse	Lymph	MS-1	1.5e-09
Mthfd1l	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-15
Mthfd1l	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Mthfd1l	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Mthfd1l	GOBP_Skeletal_System_Development	Mouse	Lymph	MS-1	2.6e-12
Mthfd1l	GOBP_Skeletal_System_Morphogenesis	Mouse	Lymph	MS-1	8.7e-13
Mthfd1l	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Mthfd1l	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Mthfd1l	GOBP_Tissue_Morphogenesis	Mouse	Lymph	MS-1	1.4e-12
Mthfd1l	GOBP_Tube_Development	Mouse	Lymph	MS-1	4.6e-09
Mthfd1l	GOBP_Tube_Formation	Mouse	Lymph	MS-1	3.5e-11
Mthfd1l	GOBP_Tube_Morphogenesis	Mouse	Lymph	MS-1	9.1e-10
Mthfd1l	GOBP_Formate_Metabolic_Process	Mouse	Lung	rep_1	9.0e-10
Mthfd1l	GOBP_Skeletal_System_Morphogenesis	Mouse	Lung	rep_1	4.0e-16
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Brain	rep_4	1.0e-07
Mthfd1l	GOBP_Embryonic_Organ_Development	Mouse	Brain	rep_7	7.0e-07
Mthfd1l	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_7	2.6e-14
Mthfd1l	GOBP_10_Formyltetrahydrofolate_Metabolic_Process	Mouse	Brain	HP_ad_rep2	5.9e-07
Mthfd1l	GOBP_Dicarboxylic_Acid_Biosynthetic_Process	Mouse	Brain	HP_ad_rep3	4.9e-07
Mthfd1l	GOBP_Tetrahydrofolate_Interconversion	Mouse	Brain	HP_ad_rep3	4.1e-14
Mthfd1l	GOBP_Vitamin_Metabolic_Process	Mouse	Brain	HP_ad_rep3	1.3e-07
Mthfd1l	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Mthfd1l	GOBP_Cranial_Skeletal_System_Development	Mouse	Brain	HP_ad_rep7	4.7e-11
Mthfd1l	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	6.2e-09
Mthfd1l	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	HP_ad_rep7	7.5e-07
Mthfd1l	GOBP_Embryonic_Neurocranium_Morphogenesis	Mouse	Brain	HP_ad_rep7	8.6e-08
Mthfd1l	GOBP_Epithelial_Tube_Formation	Mouse	Brain	HP_ad_rep7	3.1e-10
Mthfd1l	GOBP_Epithelial_Tube_Morphogenesis	Mouse	Brain	HP_ad_rep7	6.4e-12
Mthfd1l	GOBP_Epithelium_Development	Mouse	Brain	HP_ad_rep7	2.8e-08
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	6.7e-07
Mthfd1l	GOBP_Folic_Acid_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-07
Mthfd1l	GOBP_Formate_Metabolic_Process	Mouse	Brain	HP_ad_rep7	7.0e-11
Mthfd1l	GOBP_Morphogenesis_Of_An_Epithelium	Mouse	Brain	HP_ad_rep7	8.4e-09
Mthfd1l	GOBP_Morphogenesis_Of_Embryonic_Epithelium	Mouse	Brain	HP_ad_rep7	2.3e-09
Mthfd1l	GOBP_Neural_Tube_Development	Mouse	Brain	HP_ad_rep7	6.0e-12
Mthfd1l	GOBP_Neural_Tube_Formation	Mouse	Brain	HP_ad_rep7	1.5e-08
Mthfd1l	GOBP_One_Carbon_Metabolic_Process	Mouse	Brain	HP_ad_rep7	8.4e-10
Mthfd1l	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Mthfd1l	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Mthfd1l	GOBP_Skeletal_System_Development	Mouse	Brain	HP_ad_rep7	3.7e-09
Mthfd1l	GOBP_Tetrahydrofolate_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.2e-18
Mthfd1l	GOBP_Tube_Development	Mouse	Brain	HP_ad_rep7	2.0e-08
Mthfd1l	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.1e-08
Mthfd1l	GOBP_Embryonic_Skeletal_System_Development	Mouse	Brain	HP_adpolb_rep1	6.0e-10
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Biosynthetic_Process	Mouse	Brain	HP_adpolb_rep5	1.1e-07
Mthfd1l	GOBP_Embryonic_Cranial_Skeleton_Morphogenesis	Mouse	Brain	HP_adpolb_rep5	6.4e-08
Mthfd1l	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	HP_polb_rep9	6.3e-08
Mthfd1l	GOBP_Cellular_Modified_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.3e-15
Mthfd1l	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
Mthfd1l	GOBP_Embryonic_Morphogenesis	Mouse	Brain	HP_polb_rep9	3.7e-09
Mthfd1l	GOBP_Embryonic_Organ_Development	Mouse	Brain	HP_polb_rep9	9.6e-11
Mthfd1l	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Brain	HP_polb_rep9	3.5e-15
Mthfd1l	GOBP_Folic_Acid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	4.3e-17
Mthfd1l	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-11
Mthfd1l	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	3.8e-07
Mthfd1l	GOBP_Pteridine_Containing_Compound_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.3e-11
Mthfd1l	GOBP_Pteridine_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.5e-09
Mthfd1l	GOBP_Skeletal_System_Morphogenesis	Mouse	Brain	HP_polb_rep9	1.1e-07
Mthfd1l	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Mthfd1l	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09
Mthfd1l	GOBP_Tetrahydrofolate_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.1e-08
Mthfd1l	GOBP_Tissue_Morphogenesis	Mouse	Brain	HP_polb_rep9	1.2e-10
Mthfd1l	GOBP_Tube_Formation	Mouse	Brain	HP_polb_rep9	2.2e-09
Mthfd1l	GOBP_Tube_Morphogenesis	Mouse	Brain	HP_polb_rep9	4.0e-10

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Mthfd1l function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Mthfd1l function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Mthfd1l envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Mthfd1l

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Mthfd1l

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source