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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Lhfpl4 (spascer ID:269788)

Gene summary for Lhfpl4

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Lhfpl4

Gene ID

269788

Gene namelipoma HMGIC fusion partner-like protein 4
Synonyms1190004M23Rik|AI604880|B230384L07|mKIAA4027
Cytomap6|6 E3
Type of geneprotein-coding
DescriptionLHFPL tetraspan subfamily member 4 proteinGABAA receptor regulatory Lhfpl4lipoma HMGIC fusion partner-like 4 protein
Modification date20220424
UniProtAcc

Q5U4E0


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Lhfpl4

GO:0005886

plasma membrane

21873635

Component
Lhfpl4

GO:0007605

sensory perception of sound

21873635

Process
Lhfpl4

GO:0016020

membrane

21873635

Component
Lhfpl4

GO:0045211

postsynaptic membrane

21873635

Component
Lhfpl4

GO:0050811

GABA receptor binding

21873635

Function
Lhfpl4

GO:0060077

inhibitory synapse

21873635

Component
Lhfpl4

GO:0097112

gamma-aminobutyric acid receptor clustering

21873635

Process

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Spatial pattern events for Lhfpl4

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Lhfpl4MouseBrainS1 344135153.06e-06
Lhfpl4MouseBrainS2 344135151.56e-15
Lhfpl4MouseBrainS3 344135155.72e-15
Lhfpl4MouseBrainS4 344135151.37e-15
Lhfpl4MouseBrainS6 344135158.95e-08
Lhfpl4MouseBrainS7 344135152.85e-15
Lhfpl4MouseBrain08A 326376227.49e-07
Lhfpl4MouseBrain22A 326376221.90e-06
Lhfpl4MouseBrainrep_1 351413741.40e-07
Lhfpl4MouseBrainrep_4 351413744.52e-06
Lhfpl4MouseBrainrep_5 351413742.36e-13
Lhfpl4MouseEmbryorep_2 331887761.61e-09
Lhfpl4MouseBrainrep_1 334690252.37e-15
Lhfpl4MouseBrainrep_1 350277296.44e-08
Lhfpl4MouseBrainrep_2 350277291.78e-08
Lhfpl4MouseBrainrep_3 350277291.32e-15
Lhfpl4MouseBrainrep_5 350277293.09e-07
Lhfpl4MouseTesticlerep_4 347316001.57e-15
Lhfpl4MouseBrainrep_4 352106242.90e-07
Lhfpl4MouseBrainrep_5 352106243.71e-13
Lhfpl4MouseBrainrep_6 352106247.01e-10
Lhfpl4MouseBrainrep_7 352106241.73e-13

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_5_H&E
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Spatial pattern pathway has Lhfpl4 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Lhfpl4GOBP_Cell_Junction_AssemblyMouseSpinal cordCN94_E1 9.1e-06
Lhfpl4GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseSpinal cordCN94_E1 4.2e-06
Lhfpl4GOBP_Cell_Junction_OrganizationMouseSpinal cordL7bCN02_E1 4.0e-06
Lhfpl4GOBP_Nervous_System_ProcessMouseSpinal cordL7bCN02_E1 2.5e-06
Lhfpl4GOBP_Cellular_Macromolecule_LocalizationMouseSpinal cordL7CN45_C1 4.2e-07
Lhfpl4GOBP_Inhibitory_Synapse_AssemblyMouseSpinal cordL7CN45_C1 7.4e-09
Lhfpl4GOBP_Localization_Within_MembraneMouseSpinal cordL7CN45_C1 4.2e-07
Lhfpl4GOBP_Membrane_OrganizationMouseSpinal cordL7CN45_C1 2.7e-07
Lhfpl4GOBP_Postsynaptic_Membrane_OrganizationMouseSpinal cordL7CN45_C1 5.7e-07
Lhfpl4GOBP_Receptor_ClusteringMouseSpinal cordL7CN45_C1 5.2e-06
Lhfpl4GOBP_Regulation_Of_Cell_Junction_AssemblyMouseSpinal cordL7CN45_C1 1.4e-08
Lhfpl4GOBP_Regulation_Of_Synapse_AssemblyMouseSpinal cordL7CN45_C1 4.2e-07
Lhfpl4GOBP_Sensory_PerceptionMouseSpinal cordL7CN45_C1 5.0e-07
Lhfpl4GOBP_Sensory_Perception_Of_Mechanical_StimulusMouseSpinal cordL7CN45_C1 2.4e-07
Lhfpl4GOBP_Synapse_AssemblyMouseSpinal cordL7CN45_C1 1.9e-07
Lhfpl4GOBP_Synapse_OrganizationMouseSpinal cordL7CN45_C1 3.2e-07
Lhfpl4GOBP_Neurotransmitter_Gated_Ion_Channel_ClusteringMouseSpinal cordL7CN47_D1 7.1e-06
Lhfpl4GOBP_Regulation_Of_Synapse_Structure_Or_ActivityMouseSpinal cordL8CN17_E1 8.7e-07
Lhfpl4GOBP_Cell_Junction_OrganizationMouseBrainrep_27 5.8e-05
Lhfpl4GOBP_Receptor_ClusteringMouseBrainrep_27 4.2e-07
Lhfpl4GOBP_Regulation_Of_Synapse_AssemblyMouseBrainrep_27 2.4e-05
Lhfpl4GOBP_Synapse_AssemblyMouseBrainrep_27 1.4e-06
Lhfpl4GOBP_Synapse_OrganizationMouseBrainrep_27 6.2e-06
Lhfpl4GOBP_Inhibitory_Synapse_AssemblyMouseBrainrep_41 6.2e-09
Lhfpl4GOBP_Cell_Junction_AssemblyMouseBrainrep_1 1.2e-14
Lhfpl4GOBP_Cell_Junction_OrganizationMouseBrainrep_1 1.5e-30
Lhfpl4GOBP_Inhibitory_Synapse_AssemblyMouseBrainrep_1 1.7e-73
Lhfpl4GOBP_Localization_Within_MembraneMouseBrainrep_1 3.7e-07
Lhfpl4GOBP_Nervous_System_ProcessMouseBrainrep_1 1.6e-36
Lhfpl4GOBP_Postsynapse_OrganizationMouseBrainrep_1 7.8e-17
Lhfpl4GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseBrainrep_1 1.3e-27
Lhfpl4GOBP_Regulation_Of_Synapse_Structure_Or_ActivityMouseBrainrep_1 7.3e-19
Lhfpl4GOBP_Synapse_OrganizationMouseBrainrep_1 3.8e-27
Lhfpl4GOBP_Cellular_Macromolecule_LocalizationMouseBrainrep_31.6e-125
Lhfpl4GOBP_Membrane_OrganizationMouseBrainrep_3 1.9e-41
Lhfpl4GOBP_Neurotransmitter_Gated_Ion_Channel_ClusteringMouseBrainrep_3 5.2e-29
Lhfpl4GOBP_Postsynaptic_Membrane_OrganizationMouseBrainrep_3 2.0e-42
Lhfpl4GOBP_Receptor_ClusteringMouseBrainrep_3 1.8e-17
Lhfpl4GOBP_Sensory_PerceptionMouseBrainrep_3 2.9e-57
Lhfpl4GOBP_Sensory_Perception_Of_Mechanical_StimulusMouseBrainrep_31.7e-132
Lhfpl4GOBP_Regulation_Of_Cell_Junction_AssemblyMouseBrainrep_5 1.0e-14
Lhfpl4GOBP_Synapse_AssemblyMouseBrainrep_5 4.4e-21
Lhfpl4GOBP_Inhibitory_Synapse_AssemblyMouseEmbryorep_4 2.3e-08
Lhfpl4GOBP_Neurotransmitter_Gated_Ion_Channel_ClusteringMouseEmbryorep_14 4.4e-10
Lhfpl4GOBP_Postsynaptic_Membrane_OrganizationMouseEmbryorep_14 3.4e-19
Lhfpl4GOBP_Regulation_Of_Synapse_AssemblyMouseEmbryorep_14 5.0e-19
Lhfpl4GOBP_Sensory_PerceptionMouseEmbryorep_14 5.0e-07
Lhfpl4GOBP_Sensory_Perception_Of_Mechanical_StimulusMouseEmbryorep_14 1.6e-53
Lhfpl4GOBP_Nervous_System_ProcessMouseEmbryorep_1 1.4e-08
Lhfpl4GOBP_Cellular_Macromolecule_LocalizationMouseEmbryorep_2 5.5e-15
Lhfpl4GOBP_Cell_Junction_AssemblyMouseEmbryorep_3 4.6e-28
Lhfpl4GOBP_Postsynapse_OrganizationMouseEmbryorep_3 1.1e-51
Lhfpl4GOBP_Regulation_Of_Cell_Junction_AssemblyMouseEmbryorep_3 8.0e-94
Lhfpl4GOBP_Regulation_Of_Synapse_AssemblyMouseEmbryorep_3 0.0e+00
Lhfpl4GOBP_Regulation_Of_Synapse_Structure_Or_ActivityMouseEmbryorep_3 0.0e+00
Lhfpl4GOBP_Sensory_PerceptionMouseEmbryorep_3 0.0e+00
Lhfpl4GOBP_Sensory_Perception_Of_Mechanical_StimulusMouseEmbryorep_38.3e-301
Lhfpl4GOBP_Synapse_AssemblyMouseEmbryorep_3 0.0e+00
Lhfpl4GOBP_Cell_Junction_AssemblyMouseKidneyrep_2 5.4e-41
Lhfpl4GOBP_Cell_Junction_OrganizationMouseKidneyrep_2 6.2e-52
Lhfpl4GOBP_Cellular_Macromolecule_LocalizationMouseKidneyrep_2 3.5e-61
Lhfpl4GOBP_Inhibitory_Synapse_AssemblyMouseKidneyrep_2 3.1e-10
Lhfpl4GOBP_Localization_Within_MembraneMouseKidneyrep_2 2.8e-50
Lhfpl4GOBP_Membrane_OrganizationMouseKidneyrep_2 8.5e-74
Lhfpl4GOBP_Nervous_System_ProcessMouseKidneyrep_2 1.9e-90
Lhfpl4GOBP_Neurotransmitter_Gated_Ion_Channel_ClusteringMouseKidneyrep_2 2.9e-16
Lhfpl4GOBP_Postsynapse_OrganizationMouseKidneyrep_2 3.7e-17
Lhfpl4GOBP_Postsynaptic_Membrane_OrganizationMouseKidneyrep_23.3e-105
Lhfpl4GOBP_Receptor_ClusteringMouseKidneyrep_21.1e-122
Lhfpl4GOBP_Regulation_Of_Cell_Junction_AssemblyMouseKidneyrep_2 1.1e-37
Lhfpl4GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseKidneyrep_2 8.3e-40
Lhfpl4GOBP_Regulation_Of_Synapse_AssemblyMouseKidneyrep_22.1e-107
Lhfpl4GOBP_Regulation_Of_Synapse_Structure_Or_ActivityMouseKidneyrep_2 1.9e-31
Lhfpl4GOBP_Sensory_PerceptionMouseKidneyrep_2 1.4e-94
Lhfpl4GOBP_Sensory_Perception_Of_Mechanical_StimulusMouseKidneyrep_2 3.0e-69
Lhfpl4GOBP_Synapse_AssemblyMouseKidneyrep_2 6.4e-67
Lhfpl4GOBP_Synapse_OrganizationMouseKidneyrep_2 3.0e-45
Lhfpl4GOBP_Neurotransmitter_Gated_Ion_Channel_ClusteringMouseLiverCN16-D2 6.6e-07
Lhfpl4GOBP_Postsynaptic_Membrane_OrganizationMouseLiverCN16-D2 3.2e-09
Lhfpl4GOBP_Nervous_System_ProcessMouseLiverCN73-C1 1.7e-08
Lhfpl4GOBP_Receptor_ClusteringMouseLiverCN73-C1 7.0e-09
Lhfpl4GOBP_Inhibitory_Synapse_AssemblyMouseLiverrep_15 9.0e-22
Lhfpl4GOBP_Synapse_AssemblyMouseLiverrep_15 5.4e-08
Lhfpl4GOBP_Cell_Junction_OrganizationMouseLiverrep_16 1.6e-07
Lhfpl4GOBP_Neurotransmitter_Gated_Ion_Channel_ClusteringMouseLiverrep_16 4.7e-10
Lhfpl4GOBP_Postsynapse_OrganizationMouseLiverrep_16 3.7e-10
Lhfpl4GOBP_Postsynaptic_Membrane_OrganizationMouseLiverrep_16 1.4e-07
Lhfpl4GOBP_Receptor_ClusteringMouseLiverrep_16 1.3e-11
Lhfpl4GOBP_Regulation_Of_Synapse_Structure_Or_ActivityMouseLiverrep_16 2.4e-08
Lhfpl4GOBP_Cell_Junction_AssemblyMouseLymphMS-1 7.9e-08
Lhfpl4GOBP_Cellular_Macromolecule_LocalizationMouseLymphMS-1 1.1e-11
Lhfpl4GOBP_Localization_Within_MembraneMouseLymphMS-1 9.7e-08
Lhfpl4GOBP_Membrane_OrganizationMouseLymphMS-1 5.8e-20
Lhfpl4GOBP_Nervous_System_ProcessMouseLymphMS-1 1.4e-08
Lhfpl4GOBP_Regulation_Of_Cell_Junction_AssemblyMouseLymphMS-1 1.6e-13
Lhfpl4GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseLymphMS-1 2.2e-09
Lhfpl4GOBP_Regulation_Of_Synapse_AssemblyMouseLymphMS-1 3.4e-15
Lhfpl4GOBP_Regulation_Of_Synapse_Structure_Or_ActivityMouseLymphMS-1 8.5e-09
Lhfpl4GOBP_Sensory_PerceptionMouseLymphMS-1 5.2e-11
Lhfpl4GOBP_Sensory_Perception_Of_Mechanical_StimulusMouseLymphMS-1 9.0e-11
Lhfpl4GOBP_Synapse_AssemblyMouseLymphMS-1 2.5e-14
Lhfpl4GOBP_Receptor_ClusteringMouseLungrep_1 1.7e-07
Lhfpl4GOBP_Cell_Junction_AssemblyMouseBrainrep_4 6.5e-07
Lhfpl4GOBP_Cell_Junction_OrganizationMouseBrainrep_4 3.7e-07
Lhfpl4GOBP_Inhibitory_Synapse_AssemblyMouseBrainrep_42.5e-128
Lhfpl4GOBP_Neurotransmitter_Gated_Ion_Channel_ClusteringMouseBrainrep_4 1.7e-19
Lhfpl4GOBP_Postsynapse_OrganizationMouseBrainrep_4 1.2e-12
Lhfpl4GOBP_Postsynaptic_Membrane_OrganizationMouseBrainrep_4 1.2e-60
Lhfpl4GOBP_Regulation_Of_Cell_Junction_AssemblyMouseBrainrep_4 2.4e-25
Lhfpl4GOBP_Regulation_Of_Synapse_AssemblyMouseBrainrep_4 2.3e-20
Lhfpl4GOBP_Regulation_Of_Synapse_Structure_Or_ActivityMouseBrainrep_4 6.1e-16
Lhfpl4GOBP_Synapse_AssemblyMouseBrainrep_4 1.3e-86
Lhfpl4GOBP_Synapse_OrganizationMouseBrainrep_4 3.8e-17
Lhfpl4GOBP_Cell_Junction_AssemblyMouseBrainHP_ad_rep7 1.3e-11
Lhfpl4GOBP_Cell_Junction_OrganizationMouseBrainHP_ad_rep7 2.9e-10
Lhfpl4GOBP_Cellular_Macromolecule_LocalizationMouseBrainHP_ad_rep7 6.6e-10
Lhfpl4GOBP_Inhibitory_Synapse_AssemblyMouseBrainHP_ad_rep7 2.0e-15
Lhfpl4GOBP_Nervous_System_ProcessMouseBrainHP_ad_rep7 7.0e-10
Lhfpl4GOBP_Postsynaptic_Membrane_OrganizationMouseBrainHP_ad_rep7 3.9e-09
Lhfpl4GOBP_Receptor_ClusteringMouseBrainHP_ad_rep7 1.2e-11
Lhfpl4GOBP_Regulation_Of_Cell_Junction_AssemblyMouseBrainHP_ad_rep7 1.1e-09
Lhfpl4GOBP_Regulation_Of_Cellular_Component_BiogenesisMouseBrainHP_ad_rep7 6.5e-10
Lhfpl4GOBP_Regulation_Of_Synapse_AssemblyMouseBrainHP_ad_rep7 9.3e-11
Lhfpl4GOBP_Synapse_AssemblyMouseBrainHP_ad_rep7 3.0e-13
Lhfpl4GOBP_Synapse_OrganizationMouseBrainHP_ad_rep7 7.3e-08
Lhfpl4GOBP_Neurotransmitter_Gated_Ion_Channel_ClusteringMouseBrainHP_adpolb_rep1 3.1e-08
Lhfpl4GOBP_Localization_Within_MembraneMouseBrainHP_polb_rep9 1.9e-08
Lhfpl4GOBP_Membrane_OrganizationMouseBrainHP_polb_rep9 1.4e-13
Lhfpl4GOBP_Regulation_Of_Synapse_Structure_Or_ActivityMouseBrainHP_polb_rep9 5.0e-10
Lhfpl4GOBP_Sensory_PerceptionMouseBrainHP_polb_rep9 1.2e-09

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Lhfpl4 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Lhfpl4 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Lhfpl4 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Lhfpl4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Lhfpl4

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource