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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Hectd4 (spascer ID:269700)

Gene summary for Hectd4

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Hectd4
	Gene ID	269700
	Gene name	HECT domain E3 ubiquitin protein ligase 4
	Synonyms	A130010L24\|AU042671\|BC019639\|EG545802\|Gm15800\|mKIAA0614
	Cytomap	5\|5 F
	Type of gene	protein-coding
	Description	probable E3 ubiquitin-protein ligase HECTD4
	Modification date	20220503
	UniProtAcc

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for Hectd4

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Hectd4	Mouse	Brain	S1	34413515	2.07e-15
Hectd4	Mouse	Brain	S2	34413515	1.56e-15
Hectd4	Mouse	Brain	S3	34413515	1.64e-15
Hectd4	Mouse	Brain	S4	34413515	1.37e-15
Hectd4	Mouse	Brain	S6	34413515	1.46e-15
Hectd4	Mouse	Brain	S7	34413515	1.55e-15
Hectd4	Mouse	Brain	rep_1	35141374	3.58e-15
Hectd4	Mouse	Brain	rep_2	35141374	1.69e-15
Hectd4	Mouse	Brain	rep_3	35141374	5.73e-15
Hectd4	Mouse	Brain	rep_4	35141374	1.57e-15
Hectd4	Mouse	Brain	rep_5	35141374	1.47e-15
Hectd4	Mouse	Brain	rep_6	35141374	1.73e-15
Hectd4	Mouse	Embryo	1E	34210887	2.53e-06
Hectd4	Mouse	Embryo	1F	34210887	6.11e-07
Hectd4	Mouse	Embryo	2H	34210887	4.16e-10
Hectd4	Mouse	Embryo	4D	34210887	1.09e-11
Hectd4	Mouse	Embryo	4E	34210887	5.72e-12
Hectd4	Mouse	Brain	rep_1	33469025	1.30e-15
Hectd4	Mouse	Brain	rep_1	35027729	1.41e-14
Hectd4	Mouse	Brain	rep_2	35027729	1.57e-15
Hectd4	Mouse	Brain	rep_3	35027729	1.32e-15
Hectd4	Mouse	Brain	rep_4	35027729	1.76e-15
Hectd4	Mouse	Brain	rep_5	35027729	1.46e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Hectd4 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Hectd4	GOBP_Carbohydrate_Homeostasis	Mouse	Spinal cord	L7CN45_C1	6.8e-08
Hectd4	GOBP_Carbohydrate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-08
Hectd4	GOBP_Chemical_Homeostasis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Hectd4	GOBP_Homeostatic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Hectd4	GOBP_Monosaccharide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.1e-06
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Hectd4	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Hectd4	GOBP_Chemical_Homeostasis	Mouse	Brain	rep_71	8.4e-05
Hectd4	GOBP_Carbohydrate_Homeostasis	Mouse	Brain	rep_1	7.2e-09
Hectd4	GOBP_Carbohydrate_Metabolic_Process	Mouse	Brain	rep_3	1.4e-74
Hectd4	GOBP_Glucose_Metabolic_Process	Mouse	Brain	rep_3	6.3e-54
Hectd4	GOBP_Monosaccharide_Metabolic_Process	Mouse	Brain	rep_3	9.2e-62
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Brain	rep_3	1.4e-184
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Brain	rep_3	6.3e-190
Hectd4	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Hectd4	GOBP_Homeostatic_Process	Mouse	Brain	rep_7	2.5e-13
Hectd4	GOBP_Carbohydrate_Metabolic_Process	Mouse	Embryo	rep_14	1.1e-08
Hectd4	GOBP_Glucose_Metabolic_Process	Mouse	Embryo	rep_14	1.4e-21
Hectd4	GOBP_Monosaccharide_Metabolic_Process	Mouse	Embryo	rep_14	3.9e-21
Hectd4	GOBP_Carbohydrate_Metabolic_Process	Mouse	Embryo	rep_1	5.6e-24
Hectd4	GOBP_Glucose_Metabolic_Process	Mouse	Embryo	rep_1	9.4e-142
Hectd4	GOBP_Homeostatic_Process	Mouse	Embryo	rep_1	2.0e-30
Hectd4	GOBP_Monosaccharide_Metabolic_Process	Mouse	Embryo	rep_1	6.0e-95
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Embryo	rep_1	4.4e-16
Hectd4	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Embryo	rep_3	4.2e-21
Hectd4	GOBP_Carbohydrate_Homeostasis	Mouse	Kidney	rep_2	3.5e-80
Hectd4	GOBP_Carbohydrate_Metabolic_Process	Mouse	Kidney	rep_2	5.2e-99
Hectd4	GOBP_Glucose_Metabolic_Process	Mouse	Kidney	rep_2	2.6e-109
Hectd4	GOBP_Homeostatic_Process	Mouse	Kidney	rep_2	2.2e-10
Hectd4	GOBP_Monosaccharide_Metabolic_Process	Mouse	Kidney	rep_2	4.3e-127
Hectd4	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Hectd4	GOBP_Carbohydrate_Homeostasis	Mouse	Lymph	MS-1	1.3e-09
Hectd4	GOBP_Carbohydrate_Metabolic_Process	Mouse	Lymph	MS-1	5.9e-10
Hectd4	GOBP_Chemical_Homeostasis	Mouse	Lymph	MS-1	8.2e-11
Hectd4	GOBP_Glucose_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-09
Hectd4	GOBP_Homeostatic_Process	Mouse	Lymph	MS-1	2.3e-12
Hectd4	GOBP_Monosaccharide_Metabolic_Process	Mouse	Lymph	MS-1	9.5e-09
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Lymph	MS-1	1.4e-09
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Lymph	MS-1	1.4e-09
Hectd4	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Hectd4	GOBP_Carbohydrate_Homeostasis	Mouse	Brain	HP_ad_rep7	3.7e-09
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Brain	HP_ad_rep7	1.7e-09
Hectd4	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Brain	HP_ad_rep7	6.9e-09
Hectd4	GOBP_Carbohydrate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.6e-09
Hectd4	GOBP_Chemical_Homeostasis	Mouse	Brain	HP_polb_rep9	9.6e-10
Hectd4	GOBP_Glucose_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.8e-10
Hectd4	GOBP_Homeostatic_Process	Mouse	Brain	HP_polb_rep9	6.4e-11
Hectd4	GOBP_Monosaccharide_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-09
Hectd4	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Hectd4 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Hectd4 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Hectd4 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Hectd4

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Hectd4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Hectd4	C0010054	Coronary Arteriosclerosis	1	CTD_human
Hectd4	C1956346	Coronary Artery Disease	1	CTD_human