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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Mprip (spascer ID:26936)

Gene summary for Mprip

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Mprip
	Gene ID	26936
	Gene name	myosin phosphatase Rho interacting protein
	Synonyms	9530046C02\|AA536749\|AI647711\|C76423\|Gm34094\|RIP3\|Rhoip3\|mKIAA0864\|p116Rip
	Cytomap	11\|11 B1.3
	Type of gene	protein-coding
	Description	myosin phosphatase Rho-interacting proteinRho interacting protein 3Rho-interacting protein 3 (p116RIP) (RIP3)p116 Rho interacting protein
	Modification date	20220424
	UniProtAcc	P97434

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Mprip	GO:0007015	actin filament organization	21873635	Process
Mprip	GO:0015629	actin cytoskeleton	21873635	Component
Mprip	GO:0051015	actin filament binding	21873635	Function

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Spatial pattern events for Mprip

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Mprip	Mouse	Brain	S1	34413515	2.07e-15
Mprip	Mouse	Brain	S2	34413515	5.44e-15
Mprip	Mouse	Brain	S3	34413515	1.64e-15
Mprip	Mouse	Brain	S4	34413515	5.51e-11
Mprip	Mouse	Brain	S6	34413515	1.46e-15
Mprip	Mouse	Brain	S7	34413515	2.85e-15
Mprip	Mouse	Brain	08A	32637622	2.28e-07
Mprip	Mouse	Brain	13B	32637622	3.11e-06
Mprip	Mouse	Brain	36B	32637622	4.83e-14
Mprip	Mouse	Brain	rep_2	35141374	7.57e-13
Mprip	Mouse	Brain	rep_3	35141374	1.17e-11
Mprip	Mouse	Brain	rep_4	35141374	1.57e-15
Mprip	Mouse	Brain	rep_5	35141374	1.53e-14
Mprip	Mouse	Brain	rep_6	35141374	8.49e-08
Mprip	Mouse	Embryo	rep_15	33188776	5.96e-06
Mprip	Mouse	Kidney	CLP	34003797	2.19e-15
Mprip	Mouse	Kidney	IRI	34003797	2.29e-15
Mprip	Mouse	Kidney	Sham	34003797	2.58e-15
Mprip	Mouse	Kidney	rep_1	34853151	2.42e-15
Mprip	Mouse	Kidney	rep_3	34853151	2.94e-15
Mprip	Mouse	Kidney	rep_4	34853151	1.26e-14
Mprip	Mouse	Kidney	rep_5	34853151	5.45e-15
Mprip	Mouse	Brain	rep_1	33469025	1.30e-15
Mprip	Mouse	Liver	rep_21	35021063	2.71e-08
Mprip	Mouse	Brain	rep_1	35027729	9.53e-08
Mprip	Mouse	Brain	rep_2	35027729	3.32e-11
Mprip	Mouse	Brain	rep_3	35027729	2.38e-15
Mprip	Mouse	Brain	rep_4	35027729	5.87e-15
Mprip	Mouse	Brain	rep_5	35027729	5.00e-15
Mprip	Mouse	Intestine	rep_2	35149721	3.44e-15
Mprip	Mouse	Intestine	rep_4	35149721	5.16e-08
Mprip	Mouse	Testicle	rep_2	34731600	5.06e-09
Mprip	Mouse	Lymph	A1	0	1.09e-09
Mprip	Mouse	Lymph	B1	0	5.83e-12
Mprip	Mouse	Lung	rep_1	35290801	6.56e-15
Mprip	Mouse	Lung	rep_4	35290801	2.26e-11
Mprip	Mouse	Brain	rep_1	35210624	9.54e-11
Mprip	Mouse	Brain	rep_3	35210624	1.25e-07
Mprip	Mouse	Brain	rep_5	35210624	1.50e-10
Mprip	Mouse	Brain	rep_7	35210624	1.76e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_21_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Mprip envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Mprip	GOBP_Cytoskeleton_Organization	Mouse	Spinal cord	L7bCN02_E1	8.3e-06
Mprip	GOBP_Actin_Filament_Based_Process	Mouse	Spinal cord	L7CN47_C1	3.4e-06
Mprip	GOBP_Actin_Filament_Organization	Mouse	Spinal cord	L8CN17_E1	2.1e-07
Mprip	GOBP_Actin_Filament_Based_Process	Mouse	Brain	rep_1	2.1e-24
Mprip	GOBP_Actin_Filament_Organization	Mouse	Brain	rep_1	4.6e-31
Mprip	GOBP_Cytoskeleton_Organization	Mouse	Brain	rep_1	1.1e-11
Mprip	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	rep_3	6.7e-78
Mprip	GOBP_Supramolecular_Fiber_Organization	Mouse	Embryo	rep_3	0.0e+00
Mprip	GOBP_Actin_Filament_Based_Process	Mouse	Kidney	rep_2	2.6e-107
Mprip	GOBP_Actin_Filament_Organization	Mouse	Kidney	rep_2	4.0e-81
Mprip	GOBP_Cytoskeleton_Organization	Mouse	Kidney	rep_2	1.5e-44
Mprip	GOBP_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	9.5e-65
Mprip	GOBP_Actin_Filament_Based_Process	Mouse	Lymph	MS-1	1.4e-10
Mprip	GOBP_Actin_Filament_Organization	Mouse	Lymph	MS-1	4.2e-11
Mprip	GOBP_Cytoskeleton_Organization	Mouse	Lymph	MS-1	1.8e-13
Mprip	GOBP_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	1.5e-12
Mprip	GOBP_Cytoskeleton_Organization	Mouse	Brain	HP_ad_rep7	5.3e-08
Mprip	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	HP_ad_rep7	5.2e-07
Mprip	GOBP_Actin_Filament_Based_Process	Mouse	Brain	HP_polb_rep9	3.0e-07

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Mprip function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Mprip function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Mprip envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Mprip

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Mprip

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Mprip	C0043094	Weight Gain	1	CTD_human
Mprip	C3495676	Anorectal Malformations	1	GENOMICS_ENGLAND