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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Fcgr4 (spascer ID:246256)

Gene summary for Fcgr4

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Fcgr4
	Gene ID	246256
	Gene name	Fc receptor, IgG, low affinity IV
	Synonyms	4833442P21Rik\|CD16-2\|FcgRIV\|FcgammaRIV\|Fcgr3a\|Fcrl3
	Cytomap	1 H3\|1 78.53 cM
	Type of gene	protein-coding
	Description	low affinity immunoglobulin gamma Fc region receptor III-AFc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16)Fc gammaRIVFc receptor-like 3IgG Fc receptor III-Alow affinity immunoglobul
	Modification date	20220424
	UniProtAcc	A0A0B4J1G0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Fcgr4	GO:0004888	transmembrane signaling receptor activity	21873635	Function
Fcgr4	GO:0005887	integral component of plasma membrane	21873635	Component
Fcgr4	GO:0007166	cell surface receptor signaling pathway	21873635	Process
Fcgr4	GO:0050776	regulation of immune response	21873635	Process

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Spatial pattern events for Fcgr4

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Fcgr4	Mouse	Brain	S2	34413515	3.76e-07
Fcgr4	Mouse	Kidney	rep_1	34853151	7.06e-11
Fcgr4	Mouse	Liver	rep_20	35021063	9.91e-15
Fcgr4	Mouse	Intestine	rep_2	35149721	1.10e-11
Fcgr4	Mouse	Intestine	rep_3	35149721	1.97e-12
Fcgr4	Mouse	Intestine	rep_4	35149721	2.30e-15
Fcgr4	Mouse	Lymph	A1	0	3.29e-15
Fcgr4	Mouse	Lymph	B1	0	3.66e-15
Fcgr4	Mouse	Lung	rep_1	35290801	8.76e-11
Fcgr4	Mouse	Lung	rep_2	35290801	1.42e-14
Fcgr4	Mouse	Lung	rep_3	35290801	8.40e-15
Fcgr4	Mouse	Lung	rep_4	35290801	3.04e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_1_H&E
Liver_rep_20_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Fcgr4 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Fcgr4	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	CN94_E1	6.6e-06
Fcgr4	GOBP_Activation_Of_Immune_Response	Mouse	Spinal cord	L7CN45_C1	7.8e-08
Fcgr4	GOBP_Cell_Activation	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Fcgr4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Spinal cord	L7CN45_C1	9.9e-07
Fcgr4	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Fcgr4	GOBP_Fc_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	2.4e-07
Fcgr4	GOBP_Immune_Effector_Process	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Fcgr4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Spinal cord	L7CN45_C1	2.4e-06
Fcgr4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Spinal cord	L7CN45_C1	6.7e-06
Fcgr4	GOBP_Phagocytosis	Mouse	Spinal cord	L7CN45_C1	8.6e-06
Fcgr4	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Spinal cord	L7CN45_C1	8.7e-09
Fcgr4	GOBP_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Fcgr4	GOBP_Secretion	Mouse	Spinal cord	L7CN45_C1	8.1e-09
Fcgr4	GOBP_Exocytosis	Mouse	Spinal cord	L7CN47_C1	7.4e-07
Fcgr4	GOBP_Regulation_Of_Immune_Response	Mouse	Spinal cord	L8CN11_C1	4.7e-22
Fcgr4	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Spinal cord	L8CN17_E1	2.8e-06
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_27	3.0e-05
Fcgr4	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	rep_27	7.5e-06
Fcgr4	GOBP_Secretion	Mouse	Brain	rep_27	8.9e-05
Fcgr4	GOBP_Cell_Activation	Mouse	Brain	rep_72	4.6e-06
Fcgr4	GOBP_Cell_Activation	Mouse	Brain	rep_1	1.8e-07
Fcgr4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	rep_1	2.6e-13
Fcgr4	GOBP_Exocytosis	Mouse	Brain	rep_1	3.4e-73
Fcgr4	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Mouse	Brain	rep_1	6.8e-81
Fcgr4	GOBP_Fc_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	3.7e-67
Fcgr4	GOBP_Immune_Effector_Process	Mouse	Brain	rep_1	1.5e-12
Fcgr4	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Brain	rep_1	8.1e-27
Fcgr4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	rep_1	2.1e-07
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_1	1.3e-13
Fcgr4	GOBP_Phagocytosis	Mouse	Brain	rep_1	1.8e-16
Fcgr4	GOBP_Secretion	Mouse	Brain	rep_1	4.1e-45
Fcgr4	GOBP_Activation_Of_Immune_Response	Mouse	Brain	rep_3	6.5e-108
Fcgr4	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Brain	rep_3	7.6e-125
Fcgr4	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.9e-97
Fcgr4	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	rep_3	1.1e-86
Fcgr4	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.4e-111
Fcgr4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	3.3e-32
Fcgr4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Embryo	rep_6	1.4e-16
Fcgr4	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Mouse	Embryo	rep_14	2.1e-30
Fcgr4	GOBP_Fc_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	6.0e-22
Fcgr4	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_14	3.3e-15
Fcgr4	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Embryo	rep_14	5.3e-08
Fcgr4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Embryo	rep_14	3.8e-12
Fcgr4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Embryo	rep_14	2.9e-28
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Embryo	rep_14	1.7e-32
Fcgr4	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Embryo	rep_14	9.6e-07
Fcgr4	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	7.3e-23
Fcgr4	GOBP_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	9.5e-143
Fcgr4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Embryo	rep_2	3.4e-34
Fcgr4	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_2	1.7e-23
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Kidney	Nep	4.2e-26
Fcgr4	GOBP_Phagocytosis	Mouse	Kidney	Nep	2.7e-48
Fcgr4	GOBP_Activation_Of_Immune_Response	Mouse	Kidney	rep_2	5.4e-134
Fcgr4	GOBP_Cell_Activation	Mouse	Kidney	rep_2	5.1e-83
Fcgr4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Kidney	rep_2	4.3e-101
Fcgr4	GOBP_Exocytosis	Mouse	Kidney	rep_2	3.2e-107
Fcgr4	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Mouse	Kidney	rep_2	1.1e-66
Fcgr4	GOBP_Fc_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	3.7e-59
Fcgr4	GOBP_Immune_Effector_Process	Mouse	Kidney	rep_2	3.4e-107
Fcgr4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Kidney	rep_2	2.7e-133
Fcgr4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Kidney	rep_2	2.2e-110
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Kidney	rep_2	6.6e-105
Fcgr4	GOBP_Phagocytosis	Mouse	Kidney	rep_2	3.4e-104
Fcgr4	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Kidney	rep_2	8.3e-94
Fcgr4	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	1.2e-85
Fcgr4	GOBP_Regulation_Of_Immune_Response	Mouse	Kidney	rep_2	1.3e-91
Fcgr4	GOBP_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	2.5e-84
Fcgr4	GOBP_Secretion	Mouse	Kidney	rep_2	1.6e-23
Fcgr4	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Mouse	Liver	rep_15	4.9e-08
Fcgr4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Liver	rep_15	2.4e-09
Fcgr4	GOBP_Activation_Of_Immune_Response	Mouse	Liver	rep_16	5.6e-12
Fcgr4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Liver	rep_16	1.6e-18
Fcgr4	GOBP_Exocytosis	Mouse	Liver	rep_16	8.5e-07
Fcgr4	GOBP_Fc_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	1.2e-09
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Liver	rep_16	2.2e-20
Fcgr4	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Liver	rep_16	2.3e-11
Fcgr4	GOBP_Regulation_Of_Immune_Response	Mouse	Liver	rep_16	2.5e-16
Fcgr4	GOBP_Activation_Of_Immune_Response	Mouse	Lymph	MS-1	2.3e-23
Fcgr4	GOBP_Cell_Activation	Mouse	Lymph	MS-1	1.6e-18
Fcgr4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Lymph	MS-1	9.7e-16
Fcgr4	GOBP_Exocytosis	Mouse	Lymph	MS-1	1.4e-14
Fcgr4	GOBP_Fc_Receptor_Mediated_Stimulatory_Signaling_Pathway	Mouse	Lymph	MS-1	5.7e-14
Fcgr4	GOBP_Fc_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	1.5e-10
Fcgr4	GOBP_Immune_Effector_Process	Mouse	Lymph	MS-1	1.6e-18
Fcgr4	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Lymph	MS-1	2.3e-23
Fcgr4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Lymph	MS-1	5.6e-21
Fcgr4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Lymph	MS-1	1.0e-18
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Lymph	MS-1	6.6e-07
Fcgr4	GOBP_Phagocytosis	Mouse	Lymph	MS-1	9.1e-20
Fcgr4	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Lymph	MS-1	1.0e-21
Fcgr4	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	1.6e-18
Fcgr4	GOBP_Regulation_Of_Immune_Response	Mouse	Lymph	MS-1	2.3e-21
Fcgr4	GOBP_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	2.2e-14
Fcgr4	GOBP_Secretion	Mouse	Lymph	MS-1	2.3e-12
Fcgr4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	rep_4	2.9e-33
Fcgr4	GOBP_Exocytosis	Mouse	Brain	rep_4	2.4e-43
Fcgr4	GOBP_Immune_Effector_Process	Mouse	Brain	rep_4	7.2e-15
Fcgr4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	6.4e-19
Fcgr4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	rep_4	3.5e-20
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	rep_4	3.7e-62
Fcgr4	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	3.3e-10
Fcgr4	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Mouse	Brain	HP_ad_rep7	4.4e-14
Fcgr4	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Brain	HP_ad_rep7	4.6e-07
Fcgr4	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	5.5e-07
Fcgr4	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	HP_ad_rep7	2.1e-11
Fcgr4	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	1.8e-09
Fcgr4	GOBP_Secretion	Mouse	Brain	HP_ad_rep7	1.6e-08
Fcgr4	GOBP_Activation_Of_Immune_Response	Mouse	Brain	HP_polb_rep9	2.1e-07
Fcgr4	GOBP_Cell_Activation	Mouse	Brain	HP_polb_rep9	1.5e-08
Fcgr4	GOBP_Cell_Activation_Involved_In_Immune_Response	Mouse	Brain	HP_polb_rep9	8.8e-09
Fcgr4	GOBP_Exocytosis	Mouse	Brain	HP_polb_rep9	2.3e-13
Fcgr4	GOBP_Immune_Effector_Process	Mouse	Brain	HP_polb_rep9	1.0e-08
Fcgr4	GOBP_Leukocyte_Mediated_Immunity	Mouse	Brain	HP_polb_rep9	2.8e-07
Fcgr4	GOBP_Myeloid_Leukocyte_Activation	Mouse	Brain	HP_polb_rep9	2.6e-11
Fcgr4	GOBP_Phagocytosis	Mouse	Brain	HP_polb_rep9	2.5e-08

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Fcgr4 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Fcgr4 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Fcgr4 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Fcgr4

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Fcgr4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source