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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Vasn (spascer ID:246154)

Gene summary for Vasn

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Vasn

Gene ID

246154

Gene namevasorin
Synonyms2610528G05Rik|Atia|Slitl2
Cytomap16|16 A1
Type of geneprotein-coding
DescriptionvasorinSlit-like 2protein slit-like 2
Modification date20220424
UniProtAcc

Q9CZT5


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Vasn

GO:0005615

extracellular space

21873635

Component
Vasn

GO:0005886

plasma membrane

21873635

Component
Vasn

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

21873635

Process
Vasn

GO:0031012

extracellular matrix

21873635

Component
Vasn

GO:0050431

transforming growth factor beta binding

21873635

Function

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Spatial pattern events for Vasn

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
VasnMouseBrainS1 344135152.27e-08
VasnMouseBrainS2 344135151.56e-15
VasnMouseBrainS3 344135151.64e-15
VasnMouseBrainS4 344135151.37e-15
VasnMouseBrainS6 344135154.11e-09
VasnMouseBrainS7 344135151.55e-15
VasnMouseBrainrep_4 351413742.84e-15
VasnMouseKidneyCLP 340037973.77e-15
VasnMouseKidneySham 340037974.30e-15
VasnMouseKidneyrep_1 348531514.81e-11
VasnMouseBrainrep_1 334690251.30e-15
VasnMouseLiverrep_20 350210632.25e-08
VasnMouseLymphB1 07.22e-06
VasnMouseLungrep_4 352908013.04e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_4_H&E
boxplot

boxplot
Kidney_CLP_H&E
boxplot

boxplot
Kidney_Sham_H&E
boxplot

boxplot
Kidney_rep_1_H&E
boxplot

boxplot
Brain_rep_1_H&E
boxplot
Liver_rep_20_H&E
boxplot
Lung_rep_4_H&E
boxplot

boxplot


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Spatial pattern pathway has Vasn envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
VasnGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseSpinal cordCN94_E1 4.4e-07
VasnGOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_StimulusMouseSpinal cordCN94_E1 2.4e-07
VasnGOBP_Response_To_Endogenous_StimulusMouseSpinal cordCN94_E1 2.2e-06
VasnGOBP_Response_To_Redox_StateMouseSpinal cordCN94_E1 4.2e-07
VasnGOBP_Response_To_Transforming_Growth_Factor_BetaMouseSpinal cordCN94_E1 1.5e-06
VasnGOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseSpinal cordCN94_E1 2.8e-08
VasnGOBP_Cellular_Response_To_Oxygen_LevelsMouseSpinal cordL7bCN02_E1 5.7e-06
VasnGOBP_Negative_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseSpinal cordL7bCN02_E1 4.4e-06
VasnGOBP_Regulation_Of_Cellular_Response_To_Transforming_Growth_Factor_Beta_StimulusMouseSpinal cordL7bCN02_E1 5.0e-06
VasnGOBP_Epithelial_To_Mesenchymal_TransitionMouseSpinal cordL7CN45_C1 1.5e-07
VasnGOBP_Mesenchymal_Cell_DifferentiationMouseSpinal cordL7CN45_C1 1.1e-06
VasnGOBP_Negative_Regulation_Of_Cell_DifferentiationMouseSpinal cordL7CN45_C1 4.5e-10
VasnGOBP_Negative_Regulation_Of_Developmental_ProcessMouseSpinal cordL7CN45_C1 1.9e-10
VasnGOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseSpinal cordL7CN45_C1 1.1e-06
VasnGOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseSpinal cordL7CN45_C1 2.5e-06
VasnGOBP_Regulation_Of_Cell_DifferentiationMouseSpinal cordL7CN45_C1 8.5e-07
VasnGOBP_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseSpinal cordL7CN45_C1 7.0e-06
VasnGOBP_Response_To_Growth_FactorMouseSpinal cordL7CN45_C1 4.2e-06
VasnGOBP_Response_To_Oxygen_LevelsMouseSpinal cordL7CN45_C1 8.9e-08
VasnGOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseSpinal cordL7CN45_C1 7.4e-07
VasnGOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessMouseSpinal cordL8CN17_E1 2.6e-06
VasnGOBP_Negative_Regulation_Of_SignalingMouseSpinal cordL8CN17_E1 8.3e-06
VasnGOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseBrainrep_41 7.8e-05
VasnGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainrep_1 9.9e-07
VasnGOBP_Epithelial_To_Mesenchymal_TransitionMouseBrainrep_1 7.2e-47
VasnGOBP_Mesenchymal_Cell_DifferentiationMouseBrainrep_1 1.9e-31
VasnGOBP_Mesenchyme_DevelopmentMouseBrainrep_1 2.9e-34
VasnGOBP_Negative_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseBrainrep_1 7.1e-32
VasnGOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseBrainrep_1 5.1e-30
VasnGOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseBrainrep_1 6.1e-17
VasnGOBP_Regulation_Of_Cell_DifferentiationMouseBrainrep_1 2.3e-15
VasnGOBP_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseBrainrep_1 4.3e-85
VasnGOBP_Response_To_Abiotic_StimulusMouseBrainrep_1 6.0e-28
VasnGOBP_Cellular_Response_To_Oxygen_LevelsMouseBrainrep_32.1e-105
VasnGOBP_Negative_Regulation_Of_Cell_DifferentiationMouseBrainrep_3 6.9e-23
VasnGOBP_Negative_Regulation_Of_Developmental_ProcessMouseBrainrep_3 3.9e-71
VasnGOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessMouseBrainrep_32.0e-111
VasnGOBP_Negative_Regulation_Of_Response_To_StimulusMouseBrainrep_31.3e-138
VasnGOBP_Negative_Regulation_Of_SignalingMouseBrainrep_37.8e-106
VasnGOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_StimulusMouseBrainrep_3 1.4e-97
VasnGOBP_Regulation_Of_Cellular_Response_To_Transforming_Growth_Factor_Beta_StimulusMouseBrainrep_3 2.9e-70
VasnGOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseBrainrep_32.6e-112
VasnGOBP_Response_To_Endogenous_StimulusMouseBrainrep_3 6.4e-96
VasnGOBP_Response_To_Growth_FactorMouseBrainrep_3 2.7e-45
VasnGOBP_Response_To_Redox_StateMouseBrainrep_3 3.1e-24
VasnGOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseBrainrep_3 5.2e-55
VasnGOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseBrainrep_32.7e-106
VasnGOBP_Response_To_Oxygen_LevelsMouseBrainrep_7 8.1e-12
VasnGOBP_Response_To_Transforming_Growth_Factor_BetaMouseBrainrep_7 1.1e-15
VasnGOBP_Epithelial_To_Mesenchymal_TransitionMouseEmbryorep_6 2.3e-11
VasnGOBP_Cellular_Response_To_Oxygen_LevelsMouseEmbryorep_14 6.1e-37
VasnGOBP_Negative_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseEmbryorep_14 2.0e-19
VasnGOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseEmbryorep_14 7.3e-35
VasnGOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseEmbryorep_14 8.6e-30
VasnGOBP_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseEmbryorep_14 4.2e-35
VasnGOBP_Response_To_Oxygen_LevelsMouseEmbryorep_14 4.2e-19
VasnGOBP_Response_To_Redox_StateMouseEmbryorep_14 6.0e-26
VasnGOBP_Negative_Regulation_Of_Response_To_StimulusMouseEmbryorep_1 1.1e-25
VasnGOBP_Negative_Regulation_Of_SignalingMouseEmbryorep_1 5.6e-10
VasnGOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseEmbryorep_1 0.0e+00
VasnGOBP_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseEmbryorep_11.2e-144
VasnGOBP_Epithelial_To_Mesenchymal_TransitionMouseEmbryorep_2 2.4e-63
VasnGOBP_Negative_Regulation_Of_Cell_DifferentiationMouseEmbryorep_2 7.5e-38
VasnGOBP_Mesenchymal_Cell_DifferentiationMouseEmbryorep_3 1.0e-07
VasnGOBP_Mesenchyme_DevelopmentMouseEmbryorep_31.1e-182
VasnGOBP_Regulation_Of_Cell_DifferentiationMouseEmbryorep_3 6.3e-72
VasnGOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessMouseEmbryorep_5 1.8e-10
VasnGOBP_Response_To_Endogenous_StimulusMouseEmbryorep_6 2.0e-17
VasnGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyNep 4.4e-12
VasnGOBP_Response_To_Endogenous_StimulusMouseKidneyNep 6.3e-23
VasnGOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseKidneySham 2.0e-18
VasnGOBP_Cellular_Response_To_Oxygen_LevelsMouseKidneyrep_2 4.1e-85
VasnGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyrep_2 1.5e-13
VasnGOBP_Epithelial_To_Mesenchymal_TransitionMouseKidneyrep_2 3.7e-79
VasnGOBP_Mesenchymal_Cell_DifferentiationMouseKidneyrep_2 7.0e-70
VasnGOBP_Mesenchyme_DevelopmentMouseKidneyrep_2 3.6e-61
VasnGOBP_Negative_Regulation_Of_Cell_DifferentiationMouseKidneyrep_2 1.0e-68
VasnGOBP_Negative_Regulation_Of_Developmental_ProcessMouseKidneyrep_24.6e-113
VasnGOBP_Negative_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseKidneyrep_2 4.1e-61
VasnGOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessMouseKidneyrep_22.6e-120
VasnGOBP_Negative_Regulation_Of_Response_To_StimulusMouseKidneyrep_2 1.7e-39
VasnGOBP_Negative_Regulation_Of_SignalingMouseKidneyrep_2 4.0e-40
VasnGOBP_Regulation_Of_Cell_DifferentiationMouseKidneyrep_2 2.6e-14
VasnGOBP_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseKidneyrep_2 3.6e-56
VasnGOBP_Response_To_Endogenous_StimulusMouseKidneyrep_2 1.1e-44
VasnGOBP_Response_To_Growth_FactorMouseKidneyrep_2 4.7e-31
VasnGOBP_Response_To_Redox_StateMouseKidneyrep_2 2.2e-22
VasnGOBP_Negative_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseLiverCN16-D2 4.2e-14
VasnGOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseLiverCN16-D2 2.4e-07
VasnGOBP_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseLiverCN16-E1 1.8e-23
VasnGOBP_Mesenchymal_Cell_DifferentiationMouseLiverrep_15 1.5e-07
VasnGOBP_Regulation_Of_Cell_DifferentiationMouseLiverrep_16 3.6e-08
VasnGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseLymphMS-1 1.6e-14
VasnGOBP_Epithelial_To_Mesenchymal_TransitionMouseLymphMS-1 4.7e-08
VasnGOBP_Mesenchymal_Cell_DifferentiationMouseLymphMS-1 3.1e-15
VasnGOBP_Mesenchyme_DevelopmentMouseLymphMS-1 3.7e-14
VasnGOBP_Negative_Regulation_Of_Cell_DifferentiationMouseLymphMS-1 2.2e-14
VasnGOBP_Negative_Regulation_Of_Developmental_ProcessMouseLymphMS-1 4.0e-14
VasnGOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessMouseLymphMS-1 6.6e-16
VasnGOBP_Negative_Regulation_Of_Response_To_StimulusMouseLymphMS-1 1.5e-11
VasnGOBP_Negative_Regulation_Of_SignalingMouseLymphMS-1 1.0e-14
VasnGOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseLymphMS-1 1.4e-07
VasnGOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseLymphMS-1 5.3e-08
VasnGOBP_Regulation_Of_Cell_DifferentiationMouseLymphMS-1 1.3e-14
VasnGOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_StimulusMouseLymphMS-1 4.1e-16
VasnGOBP_Regulation_Of_Cellular_Response_To_Transforming_Growth_Factor_Beta_StimulusMouseLymphMS-1 3.0e-09
VasnGOBP_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseLymphMS-1 1.6e-07
VasnGOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseLymphMS-1 9.7e-10
VasnGOBP_Response_To_Abiotic_StimulusMouseLymphMS-1 1.5e-07
VasnGOBP_Response_To_Endogenous_StimulusMouseLymphMS-1 3.9e-13
VasnGOBP_Response_To_Growth_FactorMouseLymphMS-1 2.1e-10
VasnGOBP_Response_To_Oxygen_LevelsMouseLymphMS-1 5.9e-07
VasnGOBP_Response_To_Transforming_Growth_Factor_BetaMouseLymphMS-1 2.3e-15
VasnGOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseLymphMS-1 6.5e-08
VasnGOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseLymphMS-1 3.2e-11
VasnGOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessMouseLungrep_1 1.3e-17
VasnGOBP_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseLungrep_1 8.6e-08
VasnGOBP_Response_To_Endogenous_StimulusMouseLungrep_1 2.0e-30
VasnGOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseLungrep_1 1.9e-09
VasnGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainHP_ad_rep7 2.5e-10
VasnGOBP_Mesenchymal_Cell_DifferentiationMouseBrainHP_ad_rep7 8.5e-07
VasnGOBP_Negative_Regulation_Of_Developmental_ProcessMouseBrainHP_ad_rep7 1.7e-11
VasnGOBP_Response_To_Abiotic_StimulusMouseBrainHP_ad_rep7 4.3e-08
VasnGOBP_Response_To_Endogenous_StimulusMouseBrainHP_ad_rep7 6.3e-10
VasnGOBP_Response_To_Growth_FactorMouseBrainHP_ad_rep7 3.5e-10
VasnGOBP_Response_To_Redox_StateMouseBrainHP_ad_rep7 5.6e-12
VasnGOBP_Response_To_Transforming_Growth_Factor_BetaMouseBrainHP_ad_rep7 3.1e-09
VasnGOBP_Epithelial_To_Mesenchymal_TransitionMouseBrainHP_polb_rep9 2.0e-09
VasnGOBP_Negative_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseBrainHP_polb_rep9 3.1e-18
VasnGOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessMouseBrainHP_polb_rep9 1.8e-08
VasnGOBP_Negative_Regulation_Of_Response_To_StimulusMouseBrainHP_polb_rep9 3.1e-09
VasnGOBP_Negative_Regulation_Of_SignalingMouseBrainHP_polb_rep9 1.4e-11
VasnGOBP_Negative_Regulation_Of_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseBrainHP_polb_rep9 9.2e-14
VasnGOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseBrainHP_polb_rep9 1.8e-13
VasnGOBP_Regulation_Of_Cell_DifferentiationMouseBrainHP_polb_rep9 6.5e-09
VasnGOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_StimulusMouseBrainHP_polb_rep9 8.0e-10
VasnGOBP_Regulation_Of_Cellular_Response_To_Transforming_Growth_Factor_Beta_StimulusMouseBrainHP_polb_rep9 6.6e-14
VasnGOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseBrainHP_polb_rep9 1.6e-12
VasnGOBP_Response_To_Oxygen_LevelsMouseBrainHP_polb_rep9 4.0e-09
VasnGOBP_Transforming_Growth_Factor_Beta_Receptor_Signaling_PathwayMouseBrainHP_polb_rep9 5.1e-12
VasnGOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_PathwayMouseBrainHP_polb_rep9 4.8e-12
VasnGOBP_Mesenchyme_DevelopmentMouseBrainHP_wt_rep2 5.0e-08
VasnGOBP_Regulation_Of_Epithelial_To_Mesenchymal_TransitionMouseBrainHP_wt_rep2 4.8e-09

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Vasn function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Vasn function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Vasn envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Vasn

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Vasn

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource