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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Zfp536 (spascer ID:243937)

Gene summary for Zfp536

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Zfp536
	Gene ID	243937
	Gene name	zinc finger protein 536
	Synonyms	9630010P11Rik\|Znf536\|mKIAA0390
	Cytomap	7\|7 B2- B3
	Type of gene	protein-coding
	Description	zinc finger protein 536
	Modification date	20220428
	UniProtAcc	Q8K083

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Zfp536	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	21873635	Function
Zfp536	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	21873635	Function
Zfp536	GO:0005634	nucleus	21873635	Component
Zfp536	GO:0006355	regulation of transcription, DNA-templated	21873635	Process

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Spatial pattern events for Zfp536

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Zfp536	Mouse	Brain	S1	34413515	3.21e-12
Zfp536	Mouse	Brain	S2	34413515	1.56e-15
Zfp536	Mouse	Brain	S3	34413515	2.96e-11
Zfp536	Mouse	Brain	S6	34413515	2.66e-15
Zfp536	Mouse	Brain	S7	34413515	2.15e-14
Zfp536	Mouse	Brain	02A	32637622	1.39e-09
Zfp536	Mouse	Brain	03A	32637622	3.78e-06
Zfp536	Mouse	Brain	rep_3	35141374	1.64e-15
Zfp536	Mouse	Brain	rep_4	35141374	2.84e-15
Zfp536	Mouse	Brain	rep_5	35141374	1.47e-15
Zfp536	Mouse	Embryo	1G	34210887	2.60e-09
Zfp536	Mouse	Embryo	3G	34210887	3.76e-10
Zfp536	Mouse	Embryo	4E	34210887	5.57e-14
Zfp536	Mouse	Embryo	rep_2	33188776	2.97e-13
Zfp536	Mouse	Brain	rep_1	33469025	1.30e-15
Zfp536	Mouse	Brain	rep_1	35027729	1.66e-15
Zfp536	Mouse	Brain	rep_2	35027729	1.57e-15
Zfp536	Mouse	Brain	rep_3	35027729	1.32e-15
Zfp536	Mouse	Brain	rep_4	35027729	1.07e-10
Zfp536	Mouse	Brain	rep_5	35027729	1.46e-15
Zfp536	Mouse	Testicle	rep_5	34731600	2.90e-06
Zfp536	Mouse	Brain	OFB_polb_rep8	33083725	5.11e-03

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_OFB_polb_rep8_H&E

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Spatial pattern pathway has Zfp536 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Zfp536	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	1.6e-06
Zfp536	GOBP_Negative_Regulation_Of_Neuron_Differentiation	Mouse	Spinal cord	CN94_E1	1.4e-06
Zfp536	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	CN94_E1	6.2e-07
Zfp536	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	CN94_E1	2.2e-06
Zfp536	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Spinal cord	CN94_E1	1.1e-06
Zfp536	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	4.5e-10
Zfp536	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Spinal cord	L7CN45_C1	1.9e-10
Zfp536	GOBP_Negative_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	8.9e-08
Zfp536	GOBP_Neurogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Zfp536	GOBP_Neuron_Differentiation	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Zfp536	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Zfp536	GOBP_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	2.8e-08
Zfp536	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN47_C1	3.1e-07
Zfp536	GOBP_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN47_D1	6.8e-08
Zfp536	GOBP_Negative_Regulation_Of_Signaling	Mouse	Spinal cord	L8CN17_E1	8.3e-06
Zfp536	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_27	7.2e-05
Zfp536	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_27	2.8e-05
Zfp536	GOBP_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Brain	rep_41	7.8e-05
Zfp536	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	6.5e-10
Zfp536	GOBP_Neurogenesis	Mouse	Brain	rep_1	6.4e-19
Zfp536	GOBP_Neuron_Differentiation	Mouse	Brain	rep_1	8.7e-25
Zfp536	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Brain	rep_1	2.3e-15
Zfp536	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_3	1.4e-196
Zfp536	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Brain	rep_3	6.9e-23
Zfp536	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Brain	rep_3	3.9e-71
Zfp536	GOBP_Negative_Regulation_Of_Neuron_Differentiation	Mouse	Brain	rep_3	1.8e-187
Zfp536	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_3	9.4e-206
Zfp536	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	rep_3	1.3e-138
Zfp536	GOBP_Negative_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Brain	rep_3	6.0e-103
Zfp536	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	rep_3	7.8e-106
Zfp536	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_3	7.5e-168
Zfp536	GOBP_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Brain	rep_3	4.9e-88
Zfp536	GOBP_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Brain	rep_3	1.1e-43
Zfp536	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Brain	rep_5	1.2e-19
Zfp536	GOBP_Negative_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	1.8e-29
Zfp536	GOBP_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	2.8e-49
Zfp536	GOBP_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	2.3e-17
Zfp536	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Embryo	rep_1	5.7e-69
Zfp536	GOBP_Negative_Regulation_Of_Neuron_Differentiation	Mouse	Embryo	rep_1	0.0e+00
Zfp536	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Embryo	rep_1	1.1e-25
Zfp536	GOBP_Negative_Regulation_Of_Signaling	Mouse	Embryo	rep_1	5.6e-10
Zfp536	GOBP_Neurogenesis	Mouse	Embryo	rep_1	8.2e-08
Zfp536	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Embryo	rep_2	8.0e-13
Zfp536	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Embryo	rep_2	7.5e-38
Zfp536	GOBP_Negative_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Embryo	rep_2	1.1e-278
Zfp536	GOBP_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Embryo	rep_2	1.1e-278
Zfp536	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	1.5e-267
Zfp536	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Zfp536	GOBP_Neuron_Differentiation	Mouse	Embryo	rep_3	2.1e-193
Zfp536	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Embryo	rep_3	6.3e-72
Zfp536	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Embryo	rep_3	1.5e-07
Zfp536	GOBP_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Embryo	rep_5	5.0e-13
Zfp536	GOBP_Neurogenesis	Mouse	Kidney	Nep	4.6e-22
Zfp536	GOBP_Neuron_Differentiation	Mouse	Kidney	Nep	8.3e-23
Zfp536	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Kidney	rep_2	7.3e-42
Zfp536	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Kidney	rep_2	1.0e-68
Zfp536	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Kidney	rep_2	4.6e-113
Zfp536	GOBP_Negative_Regulation_Of_Neuron_Differentiation	Mouse	Kidney	rep_2	3.4e-60
Zfp536	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	7.7e-30
Zfp536	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Kidney	rep_2	1.7e-39
Zfp536	GOBP_Negative_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	2.2e-53
Zfp536	GOBP_Negative_Regulation_Of_Signaling	Mouse	Kidney	rep_2	4.0e-40
Zfp536	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	2.2e-14
Zfp536	GOBP_Neurogenesis	Mouse	Kidney	rep_2	2.4e-78
Zfp536	GOBP_Neuron_Differentiation	Mouse	Kidney	rep_2	3.9e-32
Zfp536	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Kidney	rep_2	2.6e-14
Zfp536	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Kidney	rep_2	5.7e-54
Zfp536	GOBP_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	1.3e-18
Zfp536	GOBP_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	9.4e-10
Zfp536	GOBP_Negative_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Liver	CN16-D1	2.4e-19
Zfp536	GOBP_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Liver	CN16-D1	2.2e-12
Zfp536	GOBP_Neuron_Differentiation	Mouse	Liver	CN16-D2	5.1e-07
Zfp536	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	1.6e-08
Zfp536	GOBP_Negative_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	1.7e-12
Zfp536	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Liver	rep_16	3.6e-08
Zfp536	GOBP_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Liver	rep_16	1.5e-12
Zfp536	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	2.7e-11
Zfp536	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-11
Zfp536	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Lymph	MS-1	2.2e-14
Zfp536	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Lymph	MS-1	4.0e-14
Zfp536	GOBP_Negative_Regulation_Of_Neuron_Differentiation	Mouse	Lymph	MS-1	6.2e-08
Zfp536	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	1.8e-10
Zfp536	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Lymph	MS-1	1.5e-11
Zfp536	GOBP_Negative_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	2.7e-08
Zfp536	GOBP_Negative_Regulation_Of_Signaling	Mouse	Lymph	MS-1	1.0e-14
Zfp536	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	2.2e-09
Zfp536	GOBP_Neurogenesis	Mouse	Lymph	MS-1	4.1e-08
Zfp536	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Lymph	MS-1	1.3e-14
Zfp536	GOBP_Regulation_Of_Neuron_Differentiation	Mouse	Lymph	MS-1	1.2e-08
Zfp536	GOBP_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	3.4e-11
Zfp536	GOBP_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	2.2e-17
Zfp536	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lung	rep_1	7.5e-20
Zfp536	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lung	rep_1	5.8e-10
Zfp536	GOBP_Intracellular_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	2.5e-10
Zfp536	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.3e-12
Zfp536	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Brain	HP_ad_rep7	1.7e-11
Zfp536	GOBP_Negative_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-11
Zfp536	GOBP_Negative_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	2.6e-07
Zfp536	GOBP_Negative_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.1e-13
Zfp536	GOBP_Neurogenesis	Mouse	Brain	HP_ad_rep7	3.9e-07
Zfp536	GOBP_Neuron_Differentiation	Mouse	Brain	HP_ad_rep7	3.9e-07
Zfp536	GOBP_Regulation_Of_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	1.5e-09
Zfp536	GOBP_Retinoic_Acid_Receptor_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	1.3e-12
Zfp536	GOBP_Negative_Regulation_Of_Neuron_Differentiation	Mouse	Brain	HP_polb_rep9	9.8e-12
Zfp536	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	HP_polb_rep9	3.1e-09
Zfp536	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	HP_polb_rep9	1.4e-11
Zfp536	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Brain	HP_polb_rep9	6.5e-09

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Zfp536 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Zfp536 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Zfp536 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Zfp536

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Zfp536

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source