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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Fyb2 (spascer ID:242594)

Gene summary for Fyb2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Fyb2
	Gene ID	242594
	Gene name	FYN binding protein 2
	Synonyms	1700024P16Rik\|ARAP\|C1orf168\|Gm620
	Cytomap	4\|4 C6
	Type of gene	protein-coding
	Description	FYN-binding protein 2activation-dependent, raft-recruited ADAP-like phosphoproteinuncharacterized protein C1orf168 homolog
	Modification date	20220424
	UniProtAcc	A2A995

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Fyb2	GO:0005886	plasma membrane	21873635	Component
Fyb2	GO:0007229	integrin-mediated signaling pathway	21873635	Process
Fyb2	GO:0050852	T cell receptor signaling pathway	21873635	Process
Fyb2	GO:0072659	protein localization to plasma membrane	21873635	Process

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Spatial pattern events for Fyb2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Fyb2	Mouse	Kidney	IRI	34003797	2.41e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_IRI_H&E

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Spatial pattern pathway has Fyb2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Fyb2	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	3.0e-06
Fyb2	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	CN94_E1	6.6e-06
Fyb2	GOBP_Protein_Localization_To_Cell_Periphery	Mouse	Spinal cord	CN94_E1	4.3e-06
Fyb2	GOBP_Protein_Localization_To_Plasma_Membrane	Mouse	Spinal cord	CN94_E1	8.0e-06
Fyb2	GOBP_Activation_Of_Immune_Response	Mouse	Spinal cord	L7CN45_C1	7.8e-08
Fyb2	GOBP_Antigen_Receptor_Mediated_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	9.5e-08
Fyb2	GOBP_Biological_Adhesion	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Fyb2	GOBP_Cell_Adhesion_Mediated_By_Integrin	Mouse	Spinal cord	L7CN45_C1	1.1e-08
Fyb2	GOBP_Cellular_Macromolecule_Localization	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Fyb2	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Spinal cord	L7CN45_C1	8.7e-09
Fyb2	GOBP_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Fyb2	GOBP_T_Cell_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Fyb2	GOBP_Regulation_Of_Immune_Response	Mouse	Spinal cord	L8CN11_C1	4.7e-22
Fyb2	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Spinal cord	L8CN17_E1	2.8e-06
Fyb2	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	rep_27	7.5e-06
Fyb2	GOBP_Antigen_Receptor_Mediated_Signaling_Pathway	Mouse	Brain	rep_1	1.5e-17
Fyb2	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Brain	rep_1	8.1e-27
Fyb2	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Brain	rep_1	3.5e-10
Fyb2	GOBP_Protein_Localization_To_Cell_Periphery	Mouse	Brain	rep_1	8.2e-32
Fyb2	GOBP_Protein_Localization_To_Plasma_Membrane	Mouse	Brain	rep_1	1.5e-07
Fyb2	GOBP_Activation_Of_Immune_Response	Mouse	Brain	rep_3	6.5e-108
Fyb2	GOBP_Biological_Adhesion	Mouse	Brain	rep_3	4.3e-106
Fyb2	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	rep_3	1.6e-125
Fyb2	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Brain	rep_3	7.6e-125
Fyb2	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.9e-97
Fyb2	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	rep_3	1.1e-86
Fyb2	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.4e-111
Fyb2	GOBP_T_Cell_Receptor_Signaling_Pathway	Mouse	Brain	rep_3	1.2e-157
Fyb2	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Embryo	rep_6	4.9e-29
Fyb2	GOBP_Antigen_Receptor_Mediated_Signaling_Pathway	Mouse	Embryo	rep_14	3.2e-28
Fyb2	GOBP_Cell_Adhesion_Mediated_By_Integrin	Mouse	Embryo	rep_14	5.4e-30
Fyb2	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Embryo	rep_14	5.3e-08
Fyb2	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Embryo	rep_14	9.6e-07
Fyb2	GOBP_T_Cell_Receptor_Signaling_Pathway	Mouse	Embryo	rep_14	4.2e-46
Fyb2	GOBP_Biological_Adhesion	Mouse	Embryo	rep_1	2.2e-19
Fyb2	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	7.3e-23
Fyb2	GOBP_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	9.5e-143
Fyb2	GOBP_Cellular_Macromolecule_Localization	Mouse	Embryo	rep_2	5.5e-15
Fyb2	GOBP_Cell_Adhesion_Mediated_By_Integrin	Mouse	Embryo	rep_3	0.0e+00
Fyb2	GOBP_Antigen_Receptor_Mediated_Signaling_Pathway	Mouse	Kidney	IRI	8.3e-08
Fyb2	GOBP_Activation_Of_Immune_Response	Mouse	Kidney	rep_2	5.4e-134
Fyb2	GOBP_Antigen_Receptor_Mediated_Signaling_Pathway	Mouse	Kidney	rep_2	2.1e-119
Fyb2	GOBP_Biological_Adhesion	Mouse	Kidney	rep_2	1.3e-48
Fyb2	GOBP_Cell_Adhesion_Mediated_By_Integrin	Mouse	Kidney	rep_2	1.8e-55
Fyb2	GOBP_Cellular_Macromolecule_Localization	Mouse	Kidney	rep_2	3.5e-61
Fyb2	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Kidney	rep_2	6.2e-70
Fyb2	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Kidney	rep_2	8.3e-94
Fyb2	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	1.2e-85
Fyb2	GOBP_Protein_Localization_To_Cell_Periphery	Mouse	Kidney	rep_2	1.0e-86
Fyb2	GOBP_Protein_Localization_To_Plasma_Membrane	Mouse	Kidney	rep_2	6.5e-83
Fyb2	GOBP_Regulation_Of_Immune_Response	Mouse	Kidney	rep_2	1.3e-91
Fyb2	GOBP_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	2.5e-84
Fyb2	GOBP_T_Cell_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	2.2e-102
Fyb2	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Liver	CN16-E1	2.0e-07
Fyb2	GOBP_Activation_Of_Immune_Response	Mouse	Liver	rep_16	5.6e-12
Fyb2	GOBP_Biological_Adhesion	Mouse	Liver	rep_16	2.1e-07
Fyb2	GOBP_Cell_Adhesion_Mediated_By_Integrin	Mouse	Liver	rep_16	6.6e-09
Fyb2	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Liver	rep_16	2.3e-11
Fyb2	GOBP_Regulation_Of_Immune_Response	Mouse	Liver	rep_16	2.5e-16
Fyb2	GOBP_Activation_Of_Immune_Response	Mouse	Lymph	MS-1	2.3e-23
Fyb2	GOBP_Antigen_Receptor_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	8.7e-25
Fyb2	GOBP_Biological_Adhesion	Mouse	Lymph	MS-1	8.0e-14
Fyb2	GOBP_Cell_Adhesion_Mediated_By_Integrin	Mouse	Lymph	MS-1	3.8e-13
Fyb2	GOBP_Cellular_Macromolecule_Localization	Mouse	Lymph	MS-1	1.1e-11
Fyb2	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Lymph	MS-1	2.3e-23
Fyb2	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	1.5e-10
Fyb2	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Lymph	MS-1	1.0e-21
Fyb2	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	1.6e-18
Fyb2	GOBP_Protein_Localization_To_Cell_Periphery	Mouse	Lymph	MS-1	8.7e-09
Fyb2	GOBP_Protein_Localization_To_Plasma_Membrane	Mouse	Lymph	MS-1	3.6e-07
Fyb2	GOBP_Regulation_Of_Immune_Response	Mouse	Lymph	MS-1	2.3e-21
Fyb2	GOBP_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	2.2e-14
Fyb2	GOBP_T_Cell_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	2.7e-15
Fyb2	GOBP_Biological_Adhesion	Mouse	Lung	rep_1	3.0e-22
Fyb2	GOBP_Cell_Adhesion_Mediated_By_Integrin	Mouse	Brain	HP_ad_rep2	2.5e-07
Fyb2	GOBP_Antigen_Receptor_Mediated_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	2.3e-09
Fyb2	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	HP_ad_rep7	6.6e-10
Fyb2	GOBP_Immune_Response_Regulating_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	3.3e-10
Fyb2	GOBP_Integrin_Mediated_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	9.5e-09
Fyb2	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Brain	HP_ad_rep7	4.6e-07
Fyb2	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	5.5e-07
Fyb2	GOBP_Protein_Localization_To_Plasma_Membrane	Mouse	Brain	HP_ad_rep7	3.5e-07
Fyb2	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	HP_ad_rep7	2.1e-11
Fyb2	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	1.8e-09
Fyb2	GOBP_Activation_Of_Immune_Response	Mouse	Brain	HP_polb_rep9	2.1e-07
Fyb2	GOBP_Biological_Adhesion	Mouse	Brain	HP_polb_rep9	1.5e-07
Fyb2	GOBP_Protein_Localization_To_Cell_Periphery	Mouse	Brain	HP_polb_rep9	1.5e-10
Fyb2	GOBP_T_Cell_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	2.2e-08

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Fyb2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Fyb2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Fyb2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Fyb2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Fyb2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source