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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Pde10a (spascer ID:23984)

Gene summary for Pde10a

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Pde10a
	Gene ID	23984
	Gene name	phosphodiesterase 10A
	Synonyms	-
	Cytomap	17\|17 A1
	Type of gene	protein-coding
	Description	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Adual-substrate cAMP and cGMP, cyclic nucleotide phosphodiesterase
	Modification date	20220424
	UniProtAcc	Q8CA95

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Pde10a	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	21873635	Function
Pde10a	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity	21873635	Function
Pde10a	GO:0007165	signal transduction	21873635	Process
Pde10a	GO:0010754	negative regulation of cGMP-mediated signaling	21873635	Process

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Spatial pattern events for Pde10a

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Pde10a	Mouse	Brain	S1	34413515	2.07e-15
Pde10a	Mouse	Brain	S2	34413515	1.56e-15
Pde10a	Mouse	Brain	S3	34413515	2.96e-15
Pde10a	Mouse	Brain	S4	34413515	1.37e-15
Pde10a	Mouse	Brain	S6	34413515	1.46e-15
Pde10a	Mouse	Brain	S7	34413515	1.55e-15
Pde10a	Mouse	Brain	03A	32637622	1.10e-08
Pde10a	Mouse	Brain	03B	32637622	1.03e-08
Pde10a	Mouse	Brain	04A	32637622	8.85e-14
Pde10a	Mouse	Brain	04B	32637622	5.48e-14
Pde10a	Mouse	Brain	05A	32637622	3.09e-14
Pde10a	Mouse	Brain	05B	32637622	2.80e-14
Pde10a	Mouse	Brain	06A	32637622	2.52e-14
Pde10a	Mouse	Brain	06B	32637622	1.68e-14
Pde10a	Mouse	Brain	07A	32637622	1.93e-14
Pde10a	Mouse	Brain	07B	32637622	1.82e-14
Pde10a	Mouse	Brain	08A	32637622	2.39e-14
Pde10a	Mouse	Brain	08B	32637622	3.79e-14
Pde10a	Mouse	Brain	09A	32637622	2.68e-14
Pde10a	Mouse	Brain	09B	32637622	1.89e-14
Pde10a	Mouse	Brain	10A	32637622	3.84e-14
Pde10a	Mouse	Brain	10B	32637622	3.63e-14
Pde10a	Mouse	Brain	11A	32637622	1.61e-14
Pde10a	Mouse	Brain	12A	32637622	2.09e-14
Pde10a	Mouse	Brain	12B	32637622	1.20e-14
Pde10a	Mouse	Brain	13A	32637622	3.02e-14
Pde10a	Mouse	Brain	13B	32637622	1.72e-14
Pde10a	Mouse	Brain	14A	32637622	1.38e-14
Pde10a	Mouse	Brain	14B	32637622	1.35e-14
Pde10a	Mouse	Brain	15A	32637622	2.43e-14
Pde10a	Mouse	Brain	15B	32637622	2.07e-14
Pde10a	Mouse	Brain	16A	32637622	1.75e-14
Pde10a	Mouse	Brain	16B	32637622	2.21e-14
Pde10a	Mouse	Brain	17A	32637622	1.19e-14
Pde10a	Mouse	Brain	17B	32637622	1.32e-14
Pde10a	Mouse	Brain	18A	32637622	1.20e-14
Pde10a	Mouse	Brain	18B	32637622	1.38e-14
Pde10a	Mouse	Brain	19A	32637622	1.35e-14
Pde10a	Mouse	Brain	19B	32637622	1.36e-14
Pde10a	Mouse	Brain	20A	32637622	2.42e-14
Pde10a	Mouse	Brain	20B	32637622	1.86e-14
Pde10a	Mouse	Brain	21A	32637622	4.17e-14
Pde10a	Mouse	Brain	21B	32637622	1.37e-14
Pde10a	Mouse	Brain	22A	32637622	3.50e-13
Pde10a	Mouse	Brain	22B	32637622	2.80e-14
Pde10a	Mouse	Brain	rep_1	35141374	2.02e-15
Pde10a	Mouse	Brain	rep_2	35141374	1.69e-15
Pde10a	Mouse	Brain	rep_3	35141374	1.64e-15
Pde10a	Mouse	Brain	rep_4	35141374	1.57e-15
Pde10a	Mouse	Brain	rep_5	35141374	1.47e-15
Pde10a	Mouse	Brain	rep_6	35141374	1.73e-15
Pde10a	Mouse	Embryo	2G	34210887	7.61e-07
Pde10a	Mouse	Embryo	3G	34210887	8.80e-15
Pde10a	Mouse	Embryo	4D	34210887	1.92e-10
Pde10a	Mouse	Embryo	4E	34210887	2.63e-07
Pde10a	Mouse	Brain	rep_1	33469025	1.30e-15
Pde10a	Mouse	Brain	rep_1	35027729	1.66e-15
Pde10a	Mouse	Brain	rep_2	35027729	1.57e-15
Pde10a	Mouse	Brain	rep_3	35027729	1.32e-15
Pde10a	Mouse	Brain	rep_4	35027729	1.76e-15
Pde10a	Mouse	Brain	rep_5	35027729	1.46e-15
Pde10a	Mouse	Brain	B04_E1	32702314	3.14e-06
Pde10a	Mouse	Brain	rep_1	35210624	1.74e-15
Pde10a	Mouse	Brain	rep_2	35210624	1.74e-15
Pde10a	Mouse	Brain	rep_3	35210624	1.82e-15
Pde10a	Mouse	Brain	rep_4	35210624	2.34e-15
Pde10a	Mouse	Brain	rep_5	35210624	2.07e-15
Pde10a	Mouse	Brain	rep_6	35210624	2.05e-15
Pde10a	Mouse	Brain	rep_7	35210624	1.87e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B04_E1_H&E

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Spatial pattern pathway has Pde10a envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Pde10a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Spinal cord	L7bCN01_D2	5.8e-07
Pde10a	GOBP_Cyclic_Nucleotide_Metabolic_Process	Mouse	Spinal cord	L7bCN01_D2	9.2e-06
Pde10a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Spinal cord	L7bCN02_E1	7.8e-06
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN34_C1	7.9e-06
Pde10a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Pde10a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Pde10a	GOBP_Cgmp_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Pde10a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Spinal cord	L7CN45_C1	3.7e-06
Pde10a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	8.8e-08
Pde10a	GOBP_Negative_Regulation_Of_Cgmp_Mediated_Signaling	Mouse	Spinal cord	L7CN45_C1	9.4e-09
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Pde10a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.3e-08
Pde10a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Pde10a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Pde10a	GOBP_Organophosphate_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.4e-07
Pde10a	GOBP_Organophosphate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Pde10a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-06
Pde10a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.7e-07
Pde10a	GOBP_Regulation_Of_Cgmp_Mediated_Signaling	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Pde10a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.1e-07
Pde10a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Pde10a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Pde10a	GOBP_Camp_Metabolic_Process	Mouse	Spinal cord	L7CN45_E1	2.8e-06
Pde10a	GOBP_Cgmp_Mediated_Signaling	Mouse	Spinal cord	L7CN47_C1	1.7e-06
Pde10a	GOBP_Camp_Catabolic_Process	Mouse	Spinal cord	L7CN97_E2	2.0e-07
Pde10a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L8CN11_D1	5.6e-09
Pde10a	GOBP_Negative_Regulation_Of_Signaling	Mouse	Spinal cord	L8CN17_E1	8.3e-06
Pde10a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_27	8.0e-06
Pde10a	GOBP_Cgmp_Metabolic_Process	Mouse	Brain	rep_61	7.2e-05
Pde10a	GOBP_Camp_Catabolic_Process	Mouse	Brain	rep_75	5.0e-06
Pde10a	GOBP_Negative_Regulation_Of_Cgmp_Mediated_Signaling	Mouse	Brain	rep_75	5.1e-07
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_75	8.0e-05
Pde10a	GOBP_Regulation_Of_Cgmp_Mediated_Signaling	Mouse	Brain	rep_75	2.1e-06
Pde10a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	4.5e-16
Pde10a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Brain	rep_1	7.9e-08
Pde10a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Brain	rep_1	1.1e-10
Pde10a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Brain	rep_1	5.1e-20
Pde10a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Brain	rep_3	3.4e-221
Pde10a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Pde10a	GOBP_Cgmp_Mediated_Signaling	Mouse	Brain	rep_3	6.4e-18
Pde10a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Brain	rep_3	2.3e-101
Pde10a	GOBP_Negative_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	9.2e-120
Pde10a	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	rep_3	1.3e-138
Pde10a	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	rep_3	7.8e-106
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.9e-170
Pde10a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Brain	rep_3	4.1e-202
Pde10a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Brain	rep_3	1.2e-230
Pde10a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	rep_3	7.1e-166
Pde10a	GOBP_Organophosphate_Catabolic_Process	Mouse	Brain	rep_3	6.2e-102
Pde10a	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	rep_3	8.1e-43
Pde10a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	1.3e-132
Pde10a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Pde10a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Pde10a	GOBP_Camp_Catabolic_Process	Mouse	Embryo	rep_14	2.7e-65
Pde10a	GOBP_Camp_Metabolic_Process	Mouse	Embryo	rep_14	7.0e-38
Pde10a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Embryo	rep_14	1.7e-43
Pde10a	GOBP_Cgmp_Mediated_Signaling	Mouse	Embryo	rep_14	4.0e-11
Pde10a	GOBP_Cgmp_Metabolic_Process	Mouse	Embryo	rep_14	8.6e-20
Pde10a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Embryo	rep_14	3.7e-39
Pde10a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Embryo	rep_14	1.3e-22
Pde10a	GOBP_Cyclic_Nucleotide_Metabolic_Process	Mouse	Embryo	rep_14	1.6e-64
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	1.4e-21
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_14	1.8e-12
Pde10a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Embryo	rep_14	1.8e-44
Pde10a	GOBP_Organophosphate_Catabolic_Process	Mouse	Embryo	rep_14	2.9e-51
Pde10a	GOBP_Organophosphate_Metabolic_Process	Mouse	Embryo	rep_14	2.0e-09
Pde10a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Embryo	rep_14	5.4e-32
Pde10a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_14	6.5e-20
Pde10a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Embryo	rep_14	1.0e-59
Pde10a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Pde10a	GOBP_Negative_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Embryo	rep_1	1.0e-64
Pde10a	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Embryo	rep_1	1.1e-25
Pde10a	GOBP_Negative_Regulation_Of_Signaling	Mouse	Embryo	rep_1	5.6e-10
Pde10a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Embryo	rep_1	5.7e-21
Pde10a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Pde10a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Pde10a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Embryo	rep_2	3.3e-45
Pde10a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Embryo	rep_3	0.0e+00
Pde10a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	Nep	4.2e-26
Pde10a	GOBP_Camp_Catabolic_Process	Mouse	Kidney	rep_2	2.3e-09
Pde10a	GOBP_Camp_Metabolic_Process	Mouse	Kidney	rep_2	6.1e-12
Pde10a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Kidney	rep_2	5.9e-48
Pde10a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Pde10a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Kidney	rep_2	4.1e-29
Pde10a	GOBP_Cyclic_Nucleotide_Metabolic_Process	Mouse	Kidney	rep_2	2.6e-12
Pde10a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	3.0e-37
Pde10a	GOBP_Negative_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	9.1e-83
Pde10a	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Kidney	rep_2	1.7e-39
Pde10a	GOBP_Negative_Regulation_Of_Signaling	Mouse	Kidney	rep_2	4.0e-40
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	2.0e-16
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	2.4e-27
Pde10a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Kidney	rep_2	1.2e-14
Pde10a	GOBP_Organophosphate_Catabolic_Process	Mouse	Kidney	rep_2	3.9e-15
Pde10a	GOBP_Organophosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-41
Pde10a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-17
Pde10a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	1.4e-17
Pde10a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Kidney	rep_2	2.7e-12
Pde10a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Pde10a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Pde10a	GOBP_Camp_Catabolic_Process	Mouse	Kidney	rep_3	1.5e-04
Pde10a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Liver	CN16-D1	1.1e-10
Pde10a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Liver	CN16-D1	6.9e-14
Pde10a	GOBP_Camp_Metabolic_Process	Mouse	Liver	CN16-D2	6.1e-08
Pde10a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Liver	CN16-E1	4.0e-10
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Liver	CN65-C1	5.9e-10
Pde10a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Liver	CN65-C1	4.9e-08
Pde10a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Pde10a	GOBP_Camp_Metabolic_Process	Mouse	Liver	rep_15	8.0e-08
Pde10a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Liver	rep_15	9.6e-10
Pde10a	GOBP_Cgmp_Mediated_Signaling	Mouse	Liver	rep_16	2.9e-09
Pde10a	GOBP_Cgmp_Metabolic_Process	Mouse	Liver	rep_16	2.4e-11
Pde10a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Liver	rep_16	4.7e-11
Pde10a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Liver	rep_16	5.2e-08
Pde10a	GOBP_Camp_Catabolic_Process	Mouse	Liver	rep_23	1.7e-25
Pde10a	GOBP_Cyclic_Nucleotide_Metabolic_Process	Mouse	Liver	rep_23	1.1e-07
Pde10a	GOBP_Regulation_Of_Cgmp_Mediated_Signaling	Mouse	Liver	rep_23	5.0e-39
Pde10a	GOBP_Negative_Regulation_Of_Cgmp_Mediated_Signaling	Mouse	Intestine	rep_3	6.0e-14
Pde10a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Lymph	MS-1	6.0e-17
Pde10a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Pde10a	GOBP_Cgmp_Metabolic_Process	Mouse	Lymph	MS-1	6.9e-08
Pde10a	GOBP_Cyclic_Nucleotide_Catabolic_Process	Mouse	Lymph	MS-1	2.0e-11
Pde10a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	1.8e-08
Pde10a	GOBP_Negative_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.5e-16
Pde10a	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Lymph	MS-1	1.5e-11
Pde10a	GOBP_Negative_Regulation_Of_Signaling	Mouse	Lymph	MS-1	1.0e-14
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.7e-09
Pde10a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Lymph	MS-1	2.0e-12
Pde10a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Pde10a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Pde10a	GOBP_Organophosphate_Catabolic_Process	Mouse	Lymph	MS-1	2.4e-09
Pde10a	GOBP_Organophosphate_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-07
Pde10a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Lymph	MS-1	2.9e-12
Pde10a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	8.0e-08
Pde10a	GOBP_Regulation_Of_Cgmp_Mediated_Signaling	Mouse	Lymph	MS-1	3.0e-08
Pde10a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.0e-14
Pde10a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Lymph	MS-1	2.7e-14
Pde10a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Lymph	MS-1	1.1e-10
Pde10a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Pde10a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Pde10a	GOBP_Camp_Catabolic_Process	Mouse	Lymph	MS-2	4.6e-08
Pde10a	GOBP_Cgmp_Mediated_Signaling	Mouse	Lung	rep_1	1.4e-12
Pde10a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Lung	rep_1	1.7e-11
Pde10a	GOBP_Regulation_Of_Cgmp_Mediated_Signaling	Mouse	Lung	rep_1	1.3e-08
Pde10a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_4	1.7e-17
Pde10a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Brain	rep_4	9.1e-14
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	7.8e-13
Pde10a	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Pde10a	GOBP_Purine_Containing_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.5e-07
Pde10a	GOBP_Camp_Catabolic_Process	Mouse	Brain	HP_polb_rep1	3.8e-19
Pde10a	GOBP_Carbohydrate_Derivative_Catabolic_Process	Mouse	Brain	HP_polb_rep9	4.0e-16
Pde10a	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Pde10a	GOBP_Cgmp_Mediated_Signaling	Mouse	Brain	HP_polb_rep9	3.2e-07
Pde10a	GOBP_Cyclic_Nucleotide_Mediated_Signaling	Mouse	Brain	HP_polb_rep9	6.5e-09
Pde10a	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	6.4e-16
Pde10a	GOBP_Negative_Regulation_Of_Cgmp_Mediated_Signaling	Mouse	Brain	HP_polb_rep9	7.1e-07
Pde10a	GOBP_Negative_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	9.4e-11
Pde10a	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	HP_polb_rep9	3.1e-09
Pde10a	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	HP_polb_rep9	1.4e-11
Pde10a	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	6.9e-09
Pde10a	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-19
Pde10a	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.6e-08
Pde10a	GOBP_Organophosphate_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.2e-08
Pde10a	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	7.1e-09
Pde10a	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.4e-07
Pde10a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	3.9e-11
Pde10a	GOBP_Ribonucleotide_Catabolic_Process	Mouse	Brain	HP_polb_rep9	2.7e-21
Pde10a	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Pde10a	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09
Pde10a	GOBP_Second_Messenger_Mediated_Signaling	Mouse	Brain	HP_wt_rep2	2.8e-08

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Pde10a function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Pde10a function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Pde10a envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Pde10a

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Pde10a

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Pde10a	C4310791	STRIATAL DEGENERATION, AUTOSOMAL DOMINANT 2	2	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
Pde10a	C4310792	DYSKINESIA, LIMB AND OROFACIAL, INFANTILE-ONSET	2	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
Pde10a	C0001973	Alcoholic Intoxication, Chronic	1	PSYGENET
Pde10a	C0005586	Bipolar Disorder	1	PSYGENET
Pde10a	C0033975	Psychotic Disorders	1	PSYGENET
Pde10a	C0349204	Nonorganic psychosis	1	PSYGENET