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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Esyt1 (spascer ID:23943)

Gene summary for Esyt1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Esyt1
	Gene ID	23943
	Gene name	extended synaptotagmin-like protein 1
	Synonyms	Fam62a\|Mbc2\|vp115
	Cytomap	10\|10 D3
	Type of gene	protein-coding
	Description	extended synaptotagmin-1E-Syt1family with sequence similarity 62 (C2 domain containing), member Amembrane-bound C2 domain-containing protein
	Modification date	20220424
	UniProtAcc	Q3U7R1

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Esyt1	GO:0005509	calcium ion binding	21873635	Function
Esyt1	GO:0005544	calcium-dependent phospholipid binding	21873635	Function
Esyt1	GO:0008429	phosphatidylethanolamine binding	21873635	Function
Esyt1	GO:0031210	phosphatidylcholine binding	21873635	Function
Esyt1	GO:0031227	intrinsic component of endoplasmic reticulum membrane	21873635	Component
Esyt1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	21873635	Component
Esyt1	GO:0035091	phosphatidylinositol binding	21873635	Function

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Spatial pattern events for Esyt1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Esyt1	Mouse	Brain	S1	34413515	2.40e-06
Esyt1	Mouse	Brain	S4	34413515	7.44e-08
Esyt1	Mouse	Brain	S6	34413515	5.04e-12
Esyt1	Mouse	Brain	S7	34413515	5.47e-15
Esyt1	Mouse	Brain	29B	32637622	3.51e-07
Esyt1	Mouse	Brain	30A	32637622	6.94e-07
Esyt1	Mouse	Brain	32A	32637622	8.67e-06
Esyt1	Mouse	Brain	33A	32637622	3.29e-07
Esyt1	Mouse	Brain	34A	32637622	1.12e-09
Esyt1	Mouse	Brain	35A	32637622	1.22e-06
Esyt1	Mouse	Brain	35B	32637622	3.70e-06
Esyt1	Mouse	Brain	rep_4	35141374	1.59e-09
Esyt1	Mouse	Embryo	rep_2	33188776	1.35e-07
Esyt1	Mouse	Kidney	CLP	34003797	2.19e-15
Esyt1	Mouse	Kidney	IRI	34003797	2.29e-15
Esyt1	Mouse	Kidney	Sham	34003797	2.58e-15
Esyt1	Mouse	Kidney	rep_1	34853151	2.42e-15
Esyt1	Mouse	Kidney	rep_3	34853151	6.02e-10
Esyt1	Mouse	Kidney	rep_5	34853151	5.45e-15
Esyt1	Mouse	Brain	rep_1	33469025	1.30e-15
Esyt1	Mouse	Brain	rep_4	35027729	1.39e-09
Esyt1	Mouse	Brain	rep_5	35027729	1.46e-15
Esyt1	Mouse	Intestine	rep_2	35149721	1.11e-07
Esyt1	Mouse	Intestine	rep_3	35149721	2.42e-13
Esyt1	Mouse	Testicle	rep_2	34731600	2.34e-14
Esyt1	Mouse	Lymph	A1	0	3.29e-15
Esyt1	Mouse	Lymph	B1	0	4.20e-09
Esyt1	Mouse	Lung	rep_1	35290801	6.89e-10
Esyt1	Mouse	Lung	rep_4	35290801	2.21e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_4_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Esyt1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Esyt1	GOBP_Sphingolipid_Metabolic_Process	Mouse	Spinal cord	CN94_E1	2.7e-06
Esyt1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	3.7e-06
Esyt1	GOBP_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	8.9e-07
Esyt1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Esyt1	GOBP_Endomembrane_System_Organization	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Esyt1	GOBP_Endoplasmic_Reticulum_Localization	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Esyt1	GOBP_Glycosphingolipid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.6e-06
Esyt1	GOBP_Liposaccharide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.0e-07
Esyt1	GOBP_Membrane_Lipid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.5e-06
Esyt1	GOBP_Organelle_Localization	Mouse	Spinal cord	L7CN45_C1	1.4e-08
Esyt1	GOBP_Membrane_Docking	Mouse	Spinal cord	L7CN47_C1	6.8e-07
Esyt1	GOBP_Endoplasmic_Reticulum_Plasma_Membrane_Tethering	Mouse	Spinal cord	L7CN47_D1	7.7e-06
Esyt1	GOBP_Endoplasmic_Reticulum_Plasma_Membrane_Tethering	Mouse	Brain	rep_11	9.7e-05
Esyt1	GOBP_Endoplasmic_Reticulum_Localization	Mouse	Brain	rep_41	3.0e-08
Esyt1	GOBP_Liposaccharide_Metabolic_Process	Mouse	Brain	rep_71	2.8e-05
Esyt1	GOBP_Membrane_Docking	Mouse	Brain	rep_71	9.7e-05
Esyt1	GOBP_Endomembrane_System_Organization	Mouse	Brain	rep_1	7.8e-10
Esyt1	GOBP_Endoplasmic_Reticulum_Plasma_Membrane_Tethering	Mouse	Brain	rep_1	2.3e-16
Esyt1	GOBP_Membrane_Docking	Mouse	Brain	rep_1	1.2e-57
Esyt1	GOBP_Organelle_Localization	Mouse	Brain	rep_1	1.6e-45
Esyt1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Esyt1	GOBP_Endoplasmic_Reticulum_Localization	Mouse	Brain	rep_3	9.5e-127
Esyt1	GOBP_Endoplasmic_Reticulum_Organization	Mouse	Brain	rep_3	2.4e-131
Esyt1	GOBP_Glycosphingolipid_Metabolic_Process	Mouse	Brain	rep_3	3.0e-29
Esyt1	GOBP_Lipid_Localization	Mouse	Brain	rep_3	2.0e-22
Esyt1	GOBP_Liposaccharide_Metabolic_Process	Mouse	Brain	rep_3	5.5e-108
Esyt1	GOBP_Membrane_Lipid_Metabolic_Process	Mouse	Brain	rep_3	2.1e-71
Esyt1	GOBP_Sphingolipid_Metabolic_Process	Mouse	Brain	rep_3	4.7e-60
Esyt1	GOBP_Endoplasmic_Reticulum_Plasma_Membrane_Tethering	Mouse	Embryo	rep_6	1.2e-15
Esyt1	GOBP_Endoplasmic_Reticulum_Localization	Mouse	Embryo	rep_14	9.2e-17
Esyt1	GOBP_Endoplasmic_Reticulum_Organization	Mouse	Embryo	rep_14	4.6e-28
Esyt1	GOBP_Glycosphingolipid_Metabolic_Process	Mouse	Embryo	rep_14	1.0e-22
Esyt1	GOBP_Liposaccharide_Metabolic_Process	Mouse	Embryo	rep_14	4.6e-13
Esyt1	GOBP_Membrane_Lipid_Metabolic_Process	Mouse	Embryo	rep_14	1.6e-15
Esyt1	GOBP_Sphingolipid_Metabolic_Process	Mouse	Embryo	rep_14	1.3e-29
Esyt1	GOBP_Lipid_Metabolic_Process	Mouse	Embryo	rep_1	2.1e-39
Esyt1	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	Nep	4.2e-26
Esyt1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Esyt1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	7.4e-43
Esyt1	GOBP_Endomembrane_System_Organization	Mouse	Kidney	rep_2	1.0e-161
Esyt1	GOBP_Endoplasmic_Reticulum_Localization	Mouse	Kidney	rep_2	2.3e-42
Esyt1	GOBP_Endoplasmic_Reticulum_Organization	Mouse	Kidney	rep_2	3.3e-99
Esyt1	GOBP_Endoplasmic_Reticulum_Plasma_Membrane_Tethering	Mouse	Kidney	rep_2	4.9e-10
Esyt1	GOBP_Glycosphingolipid_Metabolic_Process	Mouse	Kidney	rep_2	1.9e-46
Esyt1	GOBP_Lipid_Localization	Mouse	Kidney	rep_2	1.1e-173
Esyt1	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-78
Esyt1	GOBP_Liposaccharide_Metabolic_Process	Mouse	Kidney	rep_2	5.8e-64
Esyt1	GOBP_Membrane_Docking	Mouse	Kidney	rep_2	8.8e-36
Esyt1	GOBP_Membrane_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	6.0e-68
Esyt1	GOBP_Organelle_Localization	Mouse	Kidney	rep_2	2.9e-72
Esyt1	GOBP_Sphingolipid_Metabolic_Process	Mouse	Kidney	rep_2	2.2e-69
Esyt1	GOBP_Endoplasmic_Reticulum_Localization	Mouse	Liver	CN16-D1	3.7e-10
Esyt1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Esyt1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Liver	CN73-C1	9.9e-09
Esyt1	GOBP_Glycosphingolipid_Metabolic_Process	Mouse	Liver	CN73-C1	2.2e-07
Esyt1	GOBP_Endoplasmic_Reticulum_Localization	Mouse	Liver	rep_15	1.4e-17
Esyt1	GOBP_Endoplasmic_Reticulum_Plasma_Membrane_Tethering	Mouse	Liver	rep_15	1.4e-23
Esyt1	GOBP_Organelle_Localization	Mouse	Liver	rep_16	2.2e-21
Esyt1	GOBP_Endoplasmic_Reticulum_Localization	Mouse	Brain	rep_1	7.1e-18
Esyt1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Esyt1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	1.1e-14
Esyt1	GOBP_Endomembrane_System_Organization	Mouse	Lymph	MS-1	2.5e-09
Esyt1	GOBP_Endoplasmic_Reticulum_Organization	Mouse	Lymph	MS-1	1.0e-07
Esyt1	GOBP_Glycosphingolipid_Metabolic_Process	Mouse	Lymph	MS-1	9.2e-13
Esyt1	GOBP_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	9.7e-11
Esyt1	GOBP_Liposaccharide_Metabolic_Process	Mouse	Lymph	MS-1	6.2e-10
Esyt1	GOBP_Membrane_Docking	Mouse	Lymph	MS-1	1.3e-08
Esyt1	GOBP_Membrane_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	1.6e-07
Esyt1	GOBP_Sphingolipid_Metabolic_Process	Mouse	Lymph	MS-1	9.3e-07
Esyt1	GOBP_Organelle_Localization	Mouse	Brain	rep_4	3.3e-19
Esyt1	GOBP_Endoplasmic_Reticulum_Localization	Mouse	Brain	HP_ad_rep4	2.8e-07
Esyt1	GOBP_Endoplasmic_Reticulum_Organization	Mouse	Brain	HP_ad_rep7	1.3e-09
Esyt1	GOBP_Endoplasmic_Reticulum_Plasma_Membrane_Tethering	Mouse	Brain	HP_ad_rep7	1.1e-08
Esyt1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Esyt1	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.9e-07
Esyt1	GOBP_Endomembrane_System_Organization	Mouse	Brain	HP_polb_rep9	6.0e-11
Esyt1	GOBP_Lipid_Localization	Mouse	Brain	HP_polb_rep9	1.4e-07
Esyt1	GOBP_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-11
Esyt1	GOBP_Membrane_Docking	Mouse	Brain	HP_polb_rep9	5.0e-13
Esyt1	GOBP_Membrane_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.0e-08
Esyt1	GOBP_Organelle_Localization	Mouse	Brain	HP_polb_rep9	1.7e-09
Esyt1	GOBP_Sphingolipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.5e-08

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Esyt1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Esyt1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Esyt1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Esyt1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Esyt1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source