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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Ly6h (spascer ID:23934)

Gene summary for Ly6h

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Ly6h
	Gene ID	23934
	Gene name	lymphocyte antigen 6 complex, locus H
	Synonyms	-
	Cytomap	15\|15 D3
	Type of gene	protein-coding
	Description	lymphocyte antigen 6Hly-6H
	Modification date	20220424
	UniProtAcc	Q9WUC3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Ly6h	GO:0005886	plasma membrane	21873635	Component
Ly6h	GO:0030550	acetylcholine receptor inhibitor activity	21873635	Function
Ly6h	GO:0033130	acetylcholine receptor binding	21873635	Function
Ly6h	GO:0095500	acetylcholine receptor signaling pathway	21873635	Process

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Spatial pattern events for Ly6h

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Ly6h	Mouse	Brain	S1	34413515	2.07e-15
Ly6h	Mouse	Brain	S2	34413515	1.56e-15
Ly6h	Mouse	Brain	S3	34413515	1.64e-15
Ly6h	Mouse	Brain	S4	34413515	1.37e-15
Ly6h	Mouse	Brain	S6	34413515	1.46e-15
Ly6h	Mouse	Brain	S7	34413515	1.55e-15
Ly6h	Mouse	Brain	02A	32637622	2.86e-07
Ly6h	Mouse	Brain	02B	32637622	5.67e-13
Ly6h	Mouse	Brain	03A	32637622	1.45e-07
Ly6h	Mouse	Brain	03B	32637622	1.70e-10
Ly6h	Mouse	Brain	04B	32637622	3.88e-07
Ly6h	Mouse	Brain	05B	32637622	2.05e-09
Ly6h	Mouse	Brain	06A	32637622	2.83e-13
Ly6h	Mouse	Brain	06B	32637622	1.68e-14
Ly6h	Mouse	Brain	07A	32637622	5.45e-14
Ly6h	Mouse	Brain	07B	32637622	1.82e-14
Ly6h	Mouse	Brain	08A	32637622	2.29e-09
Ly6h	Mouse	Brain	08B	32637622	1.07e-07
Ly6h	Mouse	Brain	09A	32637622	3.04e-13
Ly6h	Mouse	Brain	09B	32637622	1.89e-14
Ly6h	Mouse	Brain	10A	32637622	3.84e-14
Ly6h	Mouse	Brain	10B	32637622	1.38e-07
Ly6h	Mouse	Brain	11A	32637622	1.61e-14
Ly6h	Mouse	Brain	12A	32637622	8.69e-07
Ly6h	Mouse	Brain	12B	32637622	9.89e-13
Ly6h	Mouse	Brain	13B	32637622	1.50e-13
Ly6h	Mouse	Brain	14A	32637622	1.38e-14
Ly6h	Mouse	Brain	14B	32637622	1.35e-14
Ly6h	Mouse	Brain	15A	32637622	3.92e-14
Ly6h	Mouse	Brain	15B	32637622	2.07e-14
Ly6h	Mouse	Brain	16A	32637622	1.75e-14
Ly6h	Mouse	Brain	16B	32637622	2.21e-14
Ly6h	Mouse	Brain	17A	32637622	1.19e-14
Ly6h	Mouse	Brain	17B	32637622	1.32e-14
Ly6h	Mouse	Brain	18A	32637622	1.20e-14
Ly6h	Mouse	Brain	18B	32637622	1.38e-14
Ly6h	Mouse	Brain	19A	32637622	1.35e-14
Ly6h	Mouse	Brain	19B	32637622	1.36e-14
Ly6h	Mouse	Brain	20A	32637622	1.49e-14
Ly6h	Mouse	Brain	20B	32637622	1.86e-14
Ly6h	Mouse	Brain	21A	32637622	2.30e-14
Ly6h	Mouse	Brain	21B	32637622	1.37e-14
Ly6h	Mouse	Brain	22A	32637622	8.87e-15
Ly6h	Mouse	Brain	22B	32637622	8.81e-15
Ly6h	Mouse	Brain	23A	32637622	2.77e-14
Ly6h	Mouse	Brain	23B	32637622	1.10e-14
Ly6h	Mouse	Brain	24A	32637622	1.61e-14
Ly6h	Mouse	Brain	24B	32637622	1.40e-14
Ly6h	Mouse	Brain	25A	32637622	1.86e-14
Ly6h	Mouse	Brain	26A	32637622	1.34e-14
Ly6h	Mouse	Brain	26B	32637622	2.02e-14
Ly6h	Mouse	Brain	27A	32637622	1.03e-14
Ly6h	Mouse	Brain	27B	32637622	1.06e-14
Ly6h	Mouse	Brain	28A	32637622	1.06e-14
Ly6h	Mouse	Brain	28B	32637622	1.24e-14
Ly6h	Mouse	Brain	29A	32637622	1.08e-14
Ly6h	Mouse	Brain	29B	32637622	1.08e-14
Ly6h	Mouse	Brain	30A	32637622	1.48e-14
Ly6h	Mouse	Brain	31A	32637622	1.59e-14
Ly6h	Mouse	Brain	32A	32637622	1.52e-14
Ly6h	Mouse	Brain	33A	32637622	1.50e-14
Ly6h	Mouse	Brain	33B	32637622	1.94e-14
Ly6h	Mouse	Brain	34A	32637622	1.42e-14
Ly6h	Mouse	Brain	34B	32637622	1.67e-14
Ly6h	Mouse	Brain	35A	32637622	1.48e-14
Ly6h	Mouse	Brain	35B	32637622	1.41e-12
Ly6h	Mouse	Brain	36A	32637622	1.24e-13
Ly6h	Mouse	Brain	36B	32637622	2.79e-13
Ly6h	Mouse	Brain	37A	32637622	4.52e-06
Ly6h	Mouse	Brain	37B	32637622	4.31e-08
Ly6h	Mouse	Brain	38A	32637622	1.06e-10
Ly6h	Mouse	Brain	38B	32637622	6.65e-09
Ly6h	Mouse	Brain	39B	32637622	4.07e-08
Ly6h	Mouse	Brain	40A	32637622	5.71e-11
Ly6h	Mouse	Brain	40B	32637622	1.94e-09
Ly6h	Mouse	Brain	rep_1	35141374	2.02e-15
Ly6h	Mouse	Brain	rep_2	35141374	1.69e-15
Ly6h	Mouse	Brain	rep_3	35141374	1.64e-15
Ly6h	Mouse	Brain	rep_4	35141374	1.57e-15
Ly6h	Mouse	Brain	rep_5	35141374	1.47e-15
Ly6h	Mouse	Brain	rep_6	35141374	1.73e-15
Ly6h	Mouse	Embryo	1D	34210887	2.48e-09
Ly6h	Mouse	Embryo	1E	34210887	5.25e-10
Ly6h	Mouse	Embryo	1F	34210887	6.08e-13
Ly6h	Mouse	Embryo	1G	34210887	1.40e-12
Ly6h	Mouse	Embryo	2G	34210887	1.84e-13
Ly6h	Mouse	Embryo	2H	34210887	5.31e-15
Ly6h	Mouse	Embryo	4E	34210887	4.53e-15
Ly6h	Mouse	Brain	rep_1	33469025	1.30e-15
Ly6h	Mouse	Brain	rep_1	35027729	1.66e-15
Ly6h	Mouse	Brain	rep_2	35027729	1.57e-15
Ly6h	Mouse	Brain	rep_3	35027729	1.32e-15
Ly6h	Mouse	Brain	rep_4	35027729	1.76e-15
Ly6h	Mouse	Brain	rep_5	35027729	1.46e-15
Ly6h	Mouse	Brain	B02_D1	32702314	1.50e-14
Ly6h	Mouse	Brain	B02_E1	32702314	1.33e-14
Ly6h	Mouse	Brain	B03_C2	32702314	3.45e-14
Ly6h	Mouse	Brain	B03_D2	32702314	2.13e-14
Ly6h	Mouse	Brain	B04_D1	32702314	1.14e-13
Ly6h	Mouse	Brain	B04_E1	32702314	9.78e-06
Ly6h	Mouse	Brain	B05_E2	32702314	1.44e-06
Ly6h	Mouse	Brain	B06_E1	32702314	2.90e-07
Ly6h	Mouse	Brain	N02_C1	32702314	3.13e-14
Ly6h	Mouse	Brain	N02_D1	32702314	2.44e-14
Ly6h	Mouse	Brain	N03_C2	32702314	2.55e-14
Ly6h	Mouse	Brain	N03_D2	32702314	1.38e-14
Ly6h	Mouse	Brain	N04_D1	32702314	3.34e-14
Ly6h	Mouse	Brain	N04_E1	32702314	3.65e-14
Ly6h	Mouse	Brain	N05_C2	32702314	1.50e-12
Ly6h	Mouse	Brain	N05_D2	32702314	1.93e-14
Ly6h	Mouse	Brain	N06_D2	32702314	2.07e-13
Ly6h	Mouse	Brain	rep_1	35210624	1.74e-15
Ly6h	Mouse	Brain	rep_2	35210624	1.74e-15
Ly6h	Mouse	Brain	rep_3	35210624	1.82e-15
Ly6h	Mouse	Brain	rep_4	35210624	2.34e-15
Ly6h	Mouse	Brain	rep_5	35210624	2.07e-15
Ly6h	Mouse	Brain	rep_6	35210624	2.05e-15
Ly6h	Mouse	Brain	rep_7	35210624	1.87e-15
Ly6h	Mouse	Brain	OFB_ad_rep4	33083725	5.68e-04
Ly6h	Mouse	Brain	OFB_adpolb_rep3	33083725	2.20e-05
Ly6h	Mouse	Brain	OFB_adpolb_rep4	33083725	1.53e-03

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_D1_H&E
Brain_B02_E1_H&E
Brain_B03_C2_H&E
Brain_B03_D2_H&E
Brain_B04_D1_H&E
Brain_B04_E1_H&E
Brain_B05_E2_H&E
Brain_B06_E1_H&E
Brain_N02_C1_H&E
Brain_N02_D1_H&E
Brain_N03_C2_H&E
Brain_N03_D2_H&E
Brain_N04_D1_H&E
Brain_N04_E1_H&E
Brain_N05_C2_H&E
Brain_N05_D2_H&E
Brain_N06_D2_H&E
Brain_OFB_ad_rep4_H&E
Brain_OFB_adpolb_rep3_H&E
Brain_OFB_adpolb_rep4_H&E

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Spatial pattern pathway has Ly6h envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Ly6h	GOBP_Animal_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	6.6e-06
Ly6h	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Spinal cord	CN94_E1	4.1e-07
Ly6h	GOBP_Response_To_Nitrogen_Compound	Mouse	Spinal cord	CN94_E1	5.6e-06
Ly6h	GOBP_Synaptic_Signaling	Mouse	Spinal cord	L7bCN02_E1	3.4e-06
Ly6h	GOBP_Postsynaptic_Signal_Transduction	Mouse	Spinal cord	L7CN32_D1	9.8e-06
Ly6h	GOBP_Cell_Cell_Signaling	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Ly6h	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Ly6h	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Ly6h	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Spinal cord	L7CN45_C1	3.7e-07
Ly6h	GOBP_Response_To_Acetylcholine	Mouse	Spinal cord	L7CN45_C1	2.8e-09
Ly6h	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Ly6h	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_27	2.0e-06
Ly6h	GOBP_Postsynaptic_Signal_Transduction	Mouse	Brain	rep_27	6.3e-10
Ly6h	GOBP_Response_To_Acetylcholine	Mouse	Brain	rep_27	2.4e-07
Ly6h	GOBP_Negative_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	rep_41	8.5e-06
Ly6h	GOBP_Cell_Cell_Signaling	Mouse	Brain	rep_1	5.1e-48
Ly6h	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Brain	rep_1	1.5e-10
Ly6h	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Brain	rep_1	1.0e-08
Ly6h	GOBP_Negative_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	rep_1	9.8e-37
Ly6h	GOBP_Postsynaptic_Signal_Transduction	Mouse	Brain	rep_1	7.7e-22
Ly6h	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	rep_1	1.1e-73
Ly6h	GOBP_Response_To_Acetylcholine	Mouse	Brain	rep_1	1.1e-23
Ly6h	GOBP_Synaptic_Signaling	Mouse	Brain	rep_1	1.9e-45
Ly6h	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_3	5.4e-57
Ly6h	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Brain	rep_3	8.2e-81
Ly6h	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	rep_3	2.5e-82
Ly6h	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Brain	rep_3	6.3e-92
Ly6h	GOBP_Negative_Regulation_Of_Signaling_Receptor_Activity	Mouse	Embryo	rep_14	2.2e-59
Ly6h	GOBP_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_1	1.7e-10
Ly6h	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Embryo	rep_3	0.0e+00
Ly6h	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Embryo	rep_3	0.0e+00
Ly6h	GOBP_Response_To_Nitrogen_Compound	Mouse	Embryo	rep_3	0.0e+00
Ly6h	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Embryo	rep_3	0.0e+00
Ly6h	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Kidney	Nep	8.3e-23
Ly6h	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	Nep	6.8e-28
Ly6h	GOBP_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	4.2e-71
Ly6h	GOBP_Cell_Cell_Signaling	Mouse	Kidney	rep_2	6.2e-72
Ly6h	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Kidney	rep_2	5.2e-82
Ly6h	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	rep_2	4.5e-89
Ly6h	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Kidney	rep_2	2.5e-99
Ly6h	GOBP_Postsynaptic_Signal_Transduction	Mouse	Kidney	rep_2	9.5e-76
Ly6h	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Kidney	rep_2	3.3e-14
Ly6h	GOBP_Response_To_Acetylcholine	Mouse	Kidney	rep_2	3.8e-53
Ly6h	GOBP_Response_To_Nitrogen_Compound	Mouse	Kidney	rep_2	1.0e-56
Ly6h	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	rep_2	6.6e-112
Ly6h	GOBP_Synaptic_Signaling	Mouse	Kidney	rep_2	2.2e-88
Ly6h	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Liver	CN73-C1	9.9e-07
Ly6h	GOBP_Postsynaptic_Signal_Transduction	Mouse	Liver	CN73-C1	2.7e-09
Ly6h	GOBP_Response_To_Acetylcholine	Mouse	Liver	CN73-C1	1.7e-08
Ly6h	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Liver	rep_16	1.0e-14
Ly6h	GOBP_Negative_Regulation_Of_Signaling_Receptor_Activity	Mouse	Liver	rep_16	1.0e-19
Ly6h	GOBP_Postsynaptic_Signal_Transduction	Mouse	Liver	rep_16	1.3e-21
Ly6h	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Liver	rep_16	1.1e-10
Ly6h	GOBP_Response_To_Acetylcholine	Mouse	Liver	rep_16	1.4e-08
Ly6h	GOBP_Synaptic_Signaling	Mouse	Liver	rep_16	7.0e-09
Ly6h	GOBP_Animal_Organ_Morphogenesis	Mouse	Lymph	MS-1	4.4e-09
Ly6h	GOBP_Cell_Cell_Signaling	Mouse	Lymph	MS-1	9.7e-11
Ly6h	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Lymph	MS-1	7.5e-11
Ly6h	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Lymph	MS-1	7.5e-11
Ly6h	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Lymph	MS-1	6.9e-11
Ly6h	GOBP_Negative_Regulation_Of_Signaling_Receptor_Activity	Mouse	Lymph	MS-1	2.8e-10
Ly6h	GOBP_Postsynaptic_Signal_Transduction	Mouse	Lymph	MS-1	3.5e-09
Ly6h	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Lymph	MS-1	9.4e-11
Ly6h	GOBP_Response_To_Acetylcholine	Mouse	Lymph	MS-1	3.9e-10
Ly6h	GOBP_Response_To_Nitrogen_Compound	Mouse	Lymph	MS-1	1.8e-09
Ly6h	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Lymph	MS-1	1.8e-09
Ly6h	GOBP_Synaptic_Signaling	Mouse	Lymph	MS-1	8.7e-07
Ly6h	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Lung	rep_1	9.4e-15
Ly6h	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Lung	rep_1	1.2e-19
Ly6h	GOBP_Negative_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	rep_4	5.8e-82
Ly6h	GOBP_Postsynaptic_Signal_Transduction	Mouse	Brain	rep_4	2.3e-109
Ly6h	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	rep_4	4.5e-26
Ly6h	GOBP_Response_To_Acetylcholine	Mouse	Brain	rep_4	9.0e-135
Ly6h	GOBP_Cell_Cell_Signaling	Mouse	Brain	HP_ad_rep7	1.6e-08
Ly6h	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Brain	HP_ad_rep7	2.8e-12
Ly6h	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Brain	HP_ad_rep7	2.6e-10
Ly6h	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Brain	HP_ad_rep7	3.4e-10
Ly6h	GOBP_Negative_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	HP_ad_rep7	1.0e-13
Ly6h	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	HP_ad_rep7	4.7e-07
Ly6h	GOBP_Response_To_Acetylcholine	Mouse	Brain	HP_ad_rep7	5.9e-07
Ly6h	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	HP_ad_rep7	3.5e-10
Ly6h	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Brain	HP_ad_rep7	4.2e-09
Ly6h	GOBP_Synaptic_Signaling	Mouse	Brain	HP_ad_rep7	7.3e-09
Ly6h	GOBP_Postsynaptic_Signal_Transduction	Mouse	Brain	HP_polb_rep9	9.0e-08

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Ly6h function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Ly6h function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Ly6h envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Ly6h

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Ly6h

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source