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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Grem2 (spascer ID:23893)

Gene summary for Grem2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Grem2
	Gene ID	23893
	Gene name	gremlin 2, DAN family BMP antagonist
	Synonyms	Gremlin2\|Prdc
	Cytomap	1\|1 H3
	Type of gene	protein-coding
	Description	gremlin-2Gremlin1cysteine knot superfamily 1, BMP antagonist 2gremlin 2 homolog, cysteine knot superfamilyprotein related to DAN and cerberus
	Modification date	20220424
	UniProtAcc	O88273

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Grem2	GO:0005615	extracellular space	21873635	Component
Grem2	GO:0009887	animal organ morphogenesis	21873635	Process
Grem2	GO:0036122	BMP binding	21873635	Function
Grem2	GO:0038098	sequestering of BMP from receptor via BMP binding	21873635	Process
Grem2	GO:0048018	receptor ligand activity	21873635	Function

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Spatial pattern events for Grem2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Grem2	Mouse	Brain	S1	34413515	2.35e-12
Grem2	Mouse	Brain	S2	34413515	1.56e-15
Grem2	Mouse	Brain	S3	34413515	2.96e-15
Grem2	Mouse	Brain	S4	34413515	1.37e-15
Grem2	Mouse	Brain	S6	34413515	1.46e-15
Grem2	Mouse	Brain	S7	34413515	1.55e-15
Grem2	Mouse	Brain	rep_1	35141374	2.02e-15
Grem2	Mouse	Brain	rep_2	35141374	5.20e-12
Grem2	Mouse	Brain	rep_3	35141374	1.64e-15
Grem2	Mouse	Brain	rep_4	35141374	1.57e-15
Grem2	Mouse	Brain	rep_5	35141374	2.14e-08
Grem2	Mouse	Brain	rep_6	35141374	4.11e-06
Grem2	Mouse	Embryo	rep_5	33188776	1.33e-11
Grem2	Mouse	Kidney	CLP	34003797	2.19e-15
Grem2	Mouse	Kidney	IRI	34003797	2.29e-15
Grem2	Mouse	Kidney	rep_3	34853151	2.94e-15
Grem2	Mouse	Brain	rep_1	33469025	1.30e-15
Grem2	Mouse	Brain	rep_1	35027729	1.66e-15
Grem2	Mouse	Brain	rep_2	35027729	1.57e-15
Grem2	Mouse	Brain	rep_3	35027729	1.32e-15
Grem2	Mouse	Brain	rep_4	35027729	1.76e-15
Grem2	Mouse	Brain	rep_5	35027729	1.46e-15
Grem2	Mouse	Intestine	rep_1	35149721	5.35e-06
Grem2	Mouse	Intestine	rep_2	35149721	5.49e-15
Grem2	Mouse	Brain	B02_E1	32702314	2.12e-08
Grem2	Mouse	Testicle	rep_3	34731600	1.94e-14
Grem2	Mouse	Lung	rep_1	35290801	1.14e-10
Grem2	Mouse	Lung	rep_3	35290801	8.40e-15
Grem2	Mouse	Brain	rep_1	35210624	3.09e-08
Grem2	Mouse	Brain	rep_2	35210624	6.05e-15
Grem2	Mouse	Brain	rep_3	35210624	6.25e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_rep_3_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_B02_E1_H&E
Lung_rep_1_H&E
Lung_rep_3_H&E

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Spatial pattern pathway has Grem2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Grem2	GOBP_Embryonic_Body_Morphogenesis	Mouse	Spinal cord	CN93_D2	6.3e-06
Grem2	GOBP_Animal_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	6.6e-06
Grem2	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	3.0e-06
Grem2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	4.4e-07
Grem2	GOBP_Negative_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Spinal cord	CN94_E1	2.4e-06
Grem2	GOBP_Regulation_Of_Binding	Mouse	Spinal cord	CN94_E1	1.4e-06
Grem2	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Spinal cord	CN94_E1	2.4e-07
Grem2	GOBP_Regulation_Of_Protein_Binding	Mouse	Spinal cord	CN94_E1	5.5e-06
Grem2	GOBP_Response_To_Bmp	Mouse	Spinal cord	CN94_E1	1.4e-08
Grem2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Spinal cord	CN94_E1	2.2e-06
Grem2	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Spinal cord	CN94_E1	2.8e-08
Grem2	GOBP_Body_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.6e-06
Grem2	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Grem2	GOBP_Embryonic_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Grem2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	2.5e-07
Grem2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	2.5e-06
Grem2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	6.9e-08
Grem2	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Spinal cord	L7CN45_C1	3.7e-07
Grem2	GOBP_Response_To_Cytokine	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Grem2	GOBP_Response_To_Growth_Factor	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Spinal cord	L7CN45_C1	8.0e-08
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Spinal cord	L7CN47_D1	4.3e-06
Grem2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Spinal cord	L8CN17_E1	8.3e-06
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Brain	rep_9	1.9e-07
Grem2	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_27	2.0e-06
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Brain	rep_27	1.6e-09
Grem2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Mouse	Brain	rep_1	9.9e-07
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Brain	rep_1	1.2e-08
Grem2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Brain	rep_1	6.1e-17
Grem2	GOBP_Regulation_Of_Binding	Mouse	Brain	rep_1	3.2e-09
Grem2	GOBP_Regulation_Of_Receptor_Binding	Mouse	Brain	rep_1	4.3e-12
Grem2	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	rep_1	1.1e-73
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Brain	rep_2	2.0e-54
Grem2	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_3	5.4e-57
Grem2	GOBP_Body_Morphogenesis	Mouse	Brain	rep_3	8.1e-105
Grem2	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	rep_3	4.9e-10
Grem2	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
Grem2	GOBP_Embryonic_Body_Morphogenesis	Mouse	Brain	rep_3	4.8e-144
Grem2	GOBP_Embryonic_Morphogenesis	Mouse	Brain	rep_3	5.0e-165
Grem2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Brain	rep_3	1.4e-193
Grem2	GOBP_Negative_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Brain	rep_3	2.5e-215
Grem2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	rep_3	1.3e-138
Grem2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	rep_3	7.8e-106
Grem2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Brain	rep_3	3.6e-150
Grem2	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Brain	rep_3	1.4e-97
Grem2	GOBP_Regulation_Of_Protein_Binding	Mouse	Brain	rep_3	1.9e-150
Grem2	GOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Brain	rep_3	2.6e-112
Grem2	GOBP_Response_To_Bmp	Mouse	Brain	rep_3	6.5e-174
Grem2	GOBP_Response_To_Cytokine	Mouse	Brain	rep_3	1.2e-08
Grem2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Brain	rep_3	6.4e-96
Grem2	GOBP_Response_To_Growth_Factor	Mouse	Brain	rep_3	2.7e-45
Grem2	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Brain	rep_3	2.7e-106
Grem2	GOBP_Body_Morphogenesis	Mouse	Embryo	rep_4	6.9e-28
Grem2	GOBP_Embryonic_Body_Morphogenesis	Mouse	Embryo	rep_6	1.9e-15
Grem2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Embryo	rep_6	1.2e-15
Grem2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Embryo	rep_6	4.3e-08
Grem2	GOBP_Response_To_Bmp	Mouse	Embryo	rep_6	1.1e-16
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Embryo	rep_14	7.6e-17
Grem2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Embryo	rep_14	8.6e-30
Grem2	GOBP_Regulation_Of_Protein_Binding	Mouse	Embryo	rep_14	9.4e-12
Grem2	GOBP_Regulation_Of_Receptor_Binding	Mouse	Embryo	rep_14	1.9e-13
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Embryo	rep_14	8.9e-41
Grem2	GOBP_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_1	1.7e-10
Grem2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Embryo	rep_1	0.0e+00
Grem2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Embryo	rep_1	1.1e-25
Grem2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Embryo	rep_1	5.6e-10
Grem2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Embryo	rep_1	0.0e+00
Grem2	GOBP_Response_To_Cytokine	Mouse	Embryo	rep_1	8.2e-211
Grem2	GOBP_Body_Morphogenesis	Mouse	Embryo	rep_2	8.4e-12
Grem2	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
Grem2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Embryo	rep_6	2.0e-17
Grem2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Mouse	Kidney	Nep	4.4e-12
Grem2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Kidney	Nep	6.3e-23
Grem2	GOBP_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	4.2e-71
Grem2	GOBP_Body_Morphogenesis	Mouse	Kidney	rep_2	7.1e-71
Grem2	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
Grem2	GOBP_Embryonic_Body_Morphogenesis	Mouse	Kidney	rep_2	9.4e-22
Grem2	GOBP_Embryonic_Morphogenesis	Mouse	Kidney	rep_2	7.3e-66
Grem2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Mouse	Kidney	rep_2	1.5e-13
Grem2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Kidney	rep_2	1.6e-12
Grem2	GOBP_Negative_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Kidney	rep_2	5.0e-10
Grem2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Kidney	rep_2	1.7e-39
Grem2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Kidney	rep_2	4.0e-40
Grem2	GOBP_Regulation_Of_Binding	Mouse	Kidney	rep_2	1.3e-38
Grem2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Kidney	rep_2	6.5e-46
Grem2	GOBP_Regulation_Of_Protein_Binding	Mouse	Kidney	rep_2	6.4e-45
Grem2	GOBP_Regulation_Of_Receptor_Binding	Mouse	Kidney	rep_2	3.5e-15
Grem2	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Kidney	rep_2	3.3e-14
Grem2	GOBP_Response_To_Bmp	Mouse	Kidney	rep_2	2.5e-29
Grem2	GOBP_Response_To_Cytokine	Mouse	Kidney	rep_2	3.1e-14
Grem2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Kidney	rep_2	1.1e-44
Grem2	GOBP_Response_To_Growth_Factor	Mouse	Kidney	rep_2	4.7e-31
Grem2	GOBP_Body_Morphogenesis	Mouse	Liver	CN16-D2	6.6e-07
Grem2	GOBP_Embryonic_Body_Morphogenesis	Mouse	Liver	CN16-D2	7.4e-09
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Liver	CN16-D2	3.4e-07
Grem2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Liver	CN16-D2	7.8e-08
Grem2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Liver	CN16-D2	2.4e-07
Grem2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Liver	CN16-D2	1.3e-07
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Liver	rep_14	3.3e-10
Grem2	GOBP_Body_Morphogenesis	Mouse	Liver	rep_15	1.0e-14
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Liver	rep_15	2.3e-33
Grem2	GOBP_Regulation_Of_Protein_Binding	Mouse	Liver	rep_16	2.3e-08
Grem2	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Liver	rep_16	1.1e-10
Grem2	GOBP_Response_To_Cytokine	Mouse	Liver	rep_16	1.4e-13
Grem2	GOBP_Embryonic_Body_Morphogenesis	Mouse	Liver	rep_20	2.8e-08
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Brain	rep_1	1.2e-15
Grem2	GOBP_Embryonic_Body_Morphogenesis	Mouse	Intestine	rep_3	3.2e-12
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Intestine	rep_3	2.7e-07
Grem2	GOBP_Animal_Organ_Morphogenesis	Mouse	Lymph	MS-1	4.4e-09
Grem2	GOBP_Body_Morphogenesis	Mouse	Lymph	MS-1	1.8e-09
Grem2	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Lymph	MS-1	6.7e-17
Grem2	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
Grem2	GOBP_Embryonic_Body_Morphogenesis	Mouse	Lymph	MS-1	4.1e-09
Grem2	GOBP_Embryonic_Morphogenesis	Mouse	Lymph	MS-1	5.6e-07
Grem2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Mouse	Lymph	MS-1	1.6e-14
Grem2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Lymph	MS-1	3.5e-08
Grem2	GOBP_Negative_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Lymph	MS-1	5.2e-14
Grem2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Lymph	MS-1	1.5e-11
Grem2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Lymph	MS-1	1.0e-14
Grem2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Lymph	MS-1	5.3e-08
Grem2	GOBP_Regulation_Of_Binding	Mouse	Lymph	MS-1	1.9e-09
Grem2	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Lymph	MS-1	4.1e-16
Grem2	GOBP_Regulation_Of_Receptor_Binding	Mouse	Lymph	MS-1	9.7e-07
Grem2	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Lymph	MS-1	9.4e-11
Grem2	GOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Lymph	MS-1	9.7e-10
Grem2	GOBP_Response_To_Bmp	Mouse	Lymph	MS-1	2.8e-10
Grem2	GOBP_Response_To_Cytokine	Mouse	Lymph	MS-1	5.7e-15
Grem2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Lymph	MS-1	3.9e-13
Grem2	GOBP_Response_To_Growth_Factor	Mouse	Lymph	MS-1	2.1e-10
Grem2	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Lymph	MS-1	3.2e-11
Grem2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Lymph	PBS	6.8e-07
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Lymph	PBS	2.1e-13
Grem2	GOBP_Body_Morphogenesis	Mouse	Lung	rep_1	6.6e-18
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Lung	rep_1	6.6e-17
Grem2	GOBP_Negative_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Lung	rep_1	3.3e-07
Grem2	GOBP_Response_To_Cytokine	Mouse	Lung	rep_1	1.2e-17
Grem2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Lung	rep_1	2.0e-30
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Lung	rep_1	1.4e-24
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Brain	rep_4	7.2e-76
Grem2	GOBP_Regulation_Of_Receptor_Binding	Mouse	Brain	rep_4	4.5e-17
Grem2	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	rep_4	4.5e-26
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Brain	rep_4	2.6e-80
Grem2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Brain	rep_7	2.2e-07
Grem2	GOBP_Extracellular_Regulation_Of_Signal_Transduction	Mouse	Brain	HP_ad_rep3	8.8e-13
Grem2	GOBP_Body_Morphogenesis	Mouse	Brain	HP_ad_rep7	1.3e-07
Grem2	GOBP_Enzyme_Linked_Receptor_Protein_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	2.5e-10
Grem2	GOBP_Negative_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Brain	HP_ad_rep7	7.1e-13
Grem2	GOBP_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Brain	HP_ad_rep7	6.0e-11
Grem2	GOBP_Regulation_Of_Signaling_Receptor_Activity	Mouse	Brain	HP_ad_rep7	4.7e-07
Grem2	GOBP_Response_To_Bmp	Mouse	Brain	HP_ad_rep7	1.4e-10
Grem2	GOBP_Response_To_Cytokine	Mouse	Brain	HP_ad_rep7	2.1e-08
Grem2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Brain	HP_ad_rep7	6.3e-10
Grem2	GOBP_Response_To_Growth_Factor	Mouse	Brain	HP_ad_rep7	3.5e-10
Grem2	GOBP_Sequestering_Of_Extracellular_Ligand_From_Receptor	Mouse	Brain	HP_ad_rep7	2.2e-13
Grem2	GOBP_Embryonic_Body_Morphogenesis	Mouse	Brain	HP_adpolb_rep1	1.7e-07
Grem2	GOBP_Negative_Regulation_Of_Bmp_Signaling_Pathway	Mouse	Brain	HP_adpolb_rep1	2.4e-07
Grem2	GOBP_Cytokine_Mediated_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	5.5e-07
Grem2	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
Grem2	GOBP_Embryonic_Morphogenesis	Mouse	Brain	HP_polb_rep9	3.7e-09
Grem2	GOBP_Negative_Regulation_Of_Response_To_Stimulus	Mouse	Brain	HP_polb_rep9	3.1e-09
Grem2	GOBP_Negative_Regulation_Of_Signaling	Mouse	Brain	HP_polb_rep9	1.4e-11
Grem2	GOBP_Negative_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	1.8e-13
Grem2	GOBP_Regulation_Of_Binding	Mouse	Brain	HP_polb_rep9	4.0e-08
Grem2	GOBP_Regulation_Of_Cellular_Response_To_Growth_Factor_Stimulus	Mouse	Brain	HP_polb_rep9	8.0e-10
Grem2	GOBP_Regulation_Of_Protein_Binding	Mouse	Brain	HP_polb_rep9	2.8e-10
Grem2	GOBP_Regulation_Of_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	1.6e-12
Grem2	GOBP_Transmembrane_Receptor_Protein_Serine_Threonine_Kinase_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	4.8e-12

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Grem2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Grem2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Grem2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Grem2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Grem2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Grem2	C4310638	TOOTH AGENESIS, SELECTIVE, 9	1	CTD_human;UNIPROT