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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Ppp2r3a (spascer ID:235542)

Gene summary for Ppp2r3a

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Ppp2r3a

Gene ID

235542

Gene nameprotein phosphatase 2, regulatory subunit B'', alpha
Synonyms3222402P14Rik|A730042E07|C530025M11Rik
Cytomap9|9 E4
Type of geneprotein-coding
Descriptionserine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Modification date20220514
UniProtAcc


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Ppp2r3a

GO:0000159

protein phosphatase type 2A complex

21873635

Component
Ppp2r3a

GO:0006470

protein dephosphorylation

21873635

Process
Ppp2r3a

GO:0019888

protein phosphatase regulator activity

21873635

Function

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Spatial pattern events for Ppp2r3a

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Ppp2r3aMouseBrainS1 344135153.57e-09
Ppp2r3aMouseBrainS2 344135151.56e-15
Ppp2r3aMouseBrainS3 344135153.14e-08
Ppp2r3aMouseBrainS4 344135151.37e-15
Ppp2r3aMouseBrainS6 344135151.46e-15
Ppp2r3aMouseBrainS7 344135151.55e-15
Ppp2r3aMouseBrain29B 326376221.32e-06
Ppp2r3aMouseBrainrep_5 351413746.39e-06
Ppp2r3aMouseEmbryorep_3 331887763.46e-08
Ppp2r3aMouseEmbryorep_4 331887768.65e-06
Ppp2r3aMouseKidneyIRI 340037977.46e-10
Ppp2r3aMouseKidneySham 340037977.83e-15
Ppp2r3aMouseKidneyrep_3 348531517.31e-12
Ppp2r3aMouseBrainrep_1 334690254.52e-15
Ppp2r3aMouseBrainrep_1 350277291.66e-15
Ppp2r3aMouseBrainrep_2 350277291.57e-15
Ppp2r3aMouseBrainrep_3 350277291.32e-15
Ppp2r3aMouseBrainrep_4 350277295.87e-15
Ppp2r3aMouseBrainrep_5 350277291.46e-15
Ppp2r3aMouseBrainrep_1 352106242.37e-14
Ppp2r3aMouseBrainrep_2 352106241.74e-15
Ppp2r3aMouseBrainrep_3 352106241.82e-15
Ppp2r3aMouseBrainrep_5 352106247.89e-13
Ppp2r3aMouseBrainrep_6 352106243.58e-06
Ppp2r3aMouseBrainrep_7 352106246.46e-06

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_5_H&E
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Kidney_IRI_H&E
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Kidney_Sham_H&E
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Kidney_rep_3_H&E
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Brain_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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boxplot
Brain_rep_5_H&E
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Spatial pattern pathway has Ppp2r3a envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Ppp2r3aGOBP_Regulation_Of_Protein_DephosphorylationMouseSpinal cordCN93_D2 6.8e-06
Ppp2r3aGOBP_Protein_DephosphorylationMouseSpinal cordCN94_E1 5.2e-07
Ppp2r3aGOBP_Regulation_Of_Phosphatase_ActivityMouseSpinal cordCN94_E1 1.6e-06
Ppp2r3aGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseSpinal cordCN94_E1 5.2e-08
Ppp2r3aGOBP_Somite_DevelopmentMouseSpinal cordCN94_E1 5.8e-06
Ppp2r3aGOBP_DephosphorylationMouseSpinal cordL7CN45_C1 3.3e-07
Ppp2r3aGOBP_Embryo_DevelopmentMouseSpinal cordL7CN45_C1 3.4e-09
Ppp2r3aGOBP_Epithelium_DevelopmentMouseSpinal cordL7CN45_C1 4.2e-06
Ppp2r3aGOBP_Regulation_Of_DephosphorylationMouseSpinal cordL7CN45_C1 1.4e-06
Ppp2r3aGOBP_Regulation_Of_Hydrolase_ActivityMouseSpinal cordL7CN45_C1 2.3e-07
Ppp2r3aGOBP_Regulation_Of_Protein_Modification_ProcessMouseSpinal cordL7CN45_C1 4.2e-07
Ppp2r3aGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseSpinal cordL8CN11_C1 3.6e-13
Ppp2r3aGOBP_Somite_DevelopmentMouseBrainrep_19 1.6e-05
Ppp2r3aGOBP_DephosphorylationMouseBrainrep_1 1.5e-40
Ppp2r3aGOBP_Protein_DephosphorylationMouseBrainrep_1 1.0e-26
Ppp2r3aGOBP_Regulation_Of_DephosphorylationMouseBrainrep_1 1.4e-28
Ppp2r3aGOBP_Regulation_Of_Phosphatase_ActivityMouseBrainrep_1 2.0e-14
Ppp2r3aGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseBrainrep_1 2.0e-07
Ppp2r3aGOBP_Regulation_Of_Protein_DephosphorylationMouseBrainrep_1 8.8e-22
Ppp2r3aGOBP_Somite_DevelopmentMouseBrainrep_1 5.1e-35
Ppp2r3aGOBP_Embryo_DevelopmentMouseBrainrep_31.3e-126
Ppp2r3aGOBP_Epithelium_DevelopmentMouseBrainrep_38.3e-102
Ppp2r3aGOBP_Regulation_Of_Hydrolase_ActivityMouseBrainrep_31.4e-120
Ppp2r3aGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseBrainrep_3 3.0e-62
Ppp2r3aGOBP_Regulation_Of_Protein_Modification_ProcessMouseBrainrep_32.2e-188
Ppp2r3aGOBP_Regulation_Of_Hydrolase_ActivityMouseEmbryorep_14 8.5e-07
Ppp2r3aGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseEmbryorep_14 6.3e-12
Ppp2r3aGOBP_Epithelium_DevelopmentMouseEmbryorep_1 1.7e-09
Ppp2r3aGOBP_Protein_DephosphorylationMouseEmbryorep_1 1.2e-29
Ppp2r3aGOBP_Somite_DevelopmentMouseEmbryorep_1 0.0e+00
Ppp2r3aGOBP_Embryo_DevelopmentMouseEmbryorep_31.2e-173
Ppp2r3aGOBP_Regulation_Of_Hydrolase_ActivityMouseKidneyNep 1.3e-36
Ppp2r3aGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseKidneyNep 4.6e-22
Ppp2r3aGOBP_Regulation_Of_Protein_Modification_ProcessMouseKidneyNep 4.6e-22
Ppp2r3aGOBP_DephosphorylationMouseKidneyrep_2 1.4e-90
Ppp2r3aGOBP_Embryo_DevelopmentMouseKidneyrep_2 7.4e-46
Ppp2r3aGOBP_Epithelium_DevelopmentMouseKidneyrep_2 3.5e-92
Ppp2r3aGOBP_Protein_DephosphorylationMouseKidneyrep_2 2.0e-69
Ppp2r3aGOBP_Regulation_Of_DephosphorylationMouseKidneyrep_2 1.8e-67
Ppp2r3aGOBP_Regulation_Of_Hydrolase_ActivityMouseKidneyrep_2 1.4e-60
Ppp2r3aGOBP_Regulation_Of_Phosphatase_ActivityMouseKidneyrep_2 2.5e-75
Ppp2r3aGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseKidneyrep_2 8.2e-73
Ppp2r3aGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseKidneyrep_2 1.3e-41
Ppp2r3aGOBP_Regulation_Of_Protein_DephosphorylationMouseKidneyrep_2 1.4e-61
Ppp2r3aGOBP_Regulation_Of_Protein_Modification_ProcessMouseKidneyrep_2 2.2e-44
Ppp2r3aGOBP_Somite_DevelopmentMouseKidneyrep_2 7.0e-46
Ppp2r3aGOBP_Regulation_Of_DephosphorylationMouseLiverCN16-E1 1.3e-11
Ppp2r3aGOBP_Regulation_Of_Protein_DephosphorylationMouseLiverCN16-E1 9.7e-13
Ppp2r3aGOBP_Somite_DevelopmentMouseLiverrep_15 3.5e-09
Ppp2r3aGOBP_DephosphorylationMouseLymphMS-1 3.6e-12
Ppp2r3aGOBP_Embryo_DevelopmentMouseLymphMS-1 2.5e-08
Ppp2r3aGOBP_Epithelium_DevelopmentMouseLymphMS-1 8.5e-09
Ppp2r3aGOBP_Protein_DephosphorylationMouseLymphMS-1 2.7e-12
Ppp2r3aGOBP_Regulation_Of_DephosphorylationMouseLymphMS-1 3.0e-12
Ppp2r3aGOBP_Regulation_Of_Hydrolase_ActivityMouseLymphMS-1 1.9e-08
Ppp2r3aGOBP_Regulation_Of_Phosphatase_ActivityMouseLymphMS-1 6.8e-12
Ppp2r3aGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseLymphMS-1 4.9e-09
Ppp2r3aGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseLymphMS-1 5.6e-12
Ppp2r3aGOBP_Regulation_Of_Protein_DephosphorylationMouseLymphMS-1 1.1e-09
Ppp2r3aGOBP_Regulation_Of_Protein_Modification_ProcessMouseLymphMS-1 1.9e-12
Ppp2r3aGOBP_Somite_DevelopmentMouseBrainrep_7 1.3e-11
Ppp2r3aGOBP_DephosphorylationMouseBrainHP_ad_rep7 3.9e-08
Ppp2r3aGOBP_Epithelium_DevelopmentMouseBrainHP_ad_rep7 2.8e-08
Ppp2r3aGOBP_Regulation_Of_Phosphatase_ActivityMouseBrainHP_ad_rep7 4.1e-07
Ppp2r3aGOBP_Regulation_Of_Phosphorus_Metabolic_ProcessMouseBrainHP_ad_rep7 1.7e-08
Ppp2r3aGOBP_Regulation_Of_Protein_Modification_ProcessMouseBrainHP_ad_rep7 1.1e-07
Ppp2r3aGOBP_Somite_DevelopmentMouseBrainHP_adpolb_rep1 1.0e-07
Ppp2r3aGOBP_Embryo_DevelopmentMouseBrainHP_polb_rep9 1.5e-10
Ppp2r3aGOBP_Regulation_Of_Hydrolase_ActivityMouseBrainHP_polb_rep9 6.0e-09
Ppp2r3aGOBP_Regulation_Of_Phosphoprotein_Phosphatase_ActivityMouseBrainHP_polb_rep9 9.3e-07

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Ppp2r3a function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Ppp2r3a function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Ppp2r3a envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Ppp2r3a

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Ppp2r3a

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Ppp2r3aC0004238Atrial Fibrillation2CTD_human
Ppp2r3aC0235480Paroxysmal atrial fibrillation2CTD_human
Ppp2r3aC2585653Persistent atrial fibrillation2CTD_human
Ppp2r3aC3468561familial atrial fibrillation2CTD_human