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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Leo1 (spascer ID:235497)

Gene summary for Leo1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Leo1
	Gene ID	235497
	Gene name	Leo1, Paf1/RNA polymerase II complex component
	Synonyms	Gm185
	Cytomap	9\|9 D
	Type of gene	protein-coding
	Description	RNA polymerase-associated protein LEO1Leo1, Paf1/RNA polymerase II complex component, homolog
	Modification date	20220424
	UniProtAcc	Q5XJE5

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Leo1	GO:0005634	nucleus	21873635	Component
Leo1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	21873635	Process
Leo1	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding	21873635	Function

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Spatial pattern events for Leo1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Leo1	Mouse	Brain	S2	34413515	2.58e-12
Leo1	Mouse	Brain	S3	34413515	1.42e-10
Leo1	Mouse	Brain	S4	34413515	1.37e-15
Leo1	Mouse	Brain	S6	34413515	2.81e-07
Leo1	Mouse	Brain	S7	34413515	2.15e-14
Leo1	Mouse	Kidney	CLP	34003797	2.57e-11
Leo1	Mouse	Kidney	Sham	34003797	7.83e-15
Leo1	Mouse	Brain	rep_1	33469025	4.52e-15
Leo1	Mouse	Brain	rep_4	35027729	2.49e-06
Leo1	Mouse	Lymph	A1	0	1.49e-12
Leo1	Mouse	Brain	rep_1	35210624	3.17e-15
Leo1	Mouse	Brain	rep_2	35210624	2.82e-11
Leo1	Mouse	Brain	rep_5	35210624	8.79e-06
Leo1	Mouse	Brain	rep_7	35210624	3.35e-11

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_Sham_H&E
Brain_rep_1_H&E
Brain_rep_4_H&E

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Spatial pattern pathway has Leo1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Leo1	GOBP_Positive_Regulation_Of_Mrna_3_End_Processing	Mouse	Spinal cord	CN93_D2	5.9e-06
Leo1	GOBP_Formation_Of_Primary_Germ_Layer	Mouse	Spinal cord	CN94_E1	3.6e-06
Leo1	GOBP_Mrna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.9e-06
Leo1	GOBP_Myeloid_Cell_Differentiation	Mouse	Spinal cord	CN94_E1	2.9e-06
Leo1	GOBP_Positive_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Spinal cord	CN94_E1	6.1e-06
Leo1	GOBP_Protein_Monoubiquitination	Mouse	Spinal cord	CN94_E1	1.3e-06
Leo1	GOBP_Regulation_Of_Hemopoiesis	Mouse	Spinal cord	CN94_E1	6.5e-06
Leo1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.8e-06
Leo1	GOBP_Mrna_Processing	Mouse	Spinal cord	L7bCN02_E1	5.5e-06
Leo1	GOBP_Positive_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Leo1	GOBP_Rna_3_End_Processing	Mouse	Spinal cord	L7bCN02_E1	8.2e-06
Leo1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Leo1	GOBP_Cell_Cell_Signaling	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Leo1	GOBP_Cell_Fate_Commitment	Mouse	Spinal cord	L7CN45_C1	5.2e-07
Leo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Spinal cord	L7CN45_C1	5.6e-07
Leo1	GOBP_Chromatin_Organization	Mouse	Spinal cord	L7CN45_C1	3.5e-07
Leo1	GOBP_Chromosome_Organization	Mouse	Spinal cord	L7CN45_C1	3.4e-08
Leo1	GOBP_Dna_Templated_Transcription_Elongation	Mouse	Spinal cord	L7CN45_C1	6.4e-06
Leo1	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Leo1	GOBP_Embryonic_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Leo1	GOBP_Endoderm_Development	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Leo1	GOBP_Endoderm_Formation	Mouse	Spinal cord	L7CN45_C1	3.7e-08
Leo1	GOBP_Endodermal_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	3.1e-06
Leo1	GOBP_Gastrulation	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Leo1	GOBP_Histone_Monoubiquitination	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Leo1	GOBP_Histone_Ubiquitination	Mouse	Spinal cord	L7CN45_C1	9.9e-07
Leo1	GOBP_Immune_System_Development	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Leo1	GOBP_Mrna_3_End_Processing	Mouse	Spinal cord	L7CN45_C1	9.8e-06
Leo1	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	4.5e-10
Leo1	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Spinal cord	L7CN45_C1	1.9e-10
Leo1	GOBP_Negative_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	2.3e-08
Leo1	GOBP_Positive_Regulation_Of_Mrna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.3e-06
Leo1	GOBP_Positive_Regulation_Of_Mrna_Processing	Mouse	Spinal cord	L7CN45_C1	8.6e-07
Leo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Leo1	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Leo1	GOBP_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Leo1	GOBP_Regulation_Of_Mrna_Processing	Mouse	Spinal cord	L7CN45_C1	3.9e-07
Leo1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Spinal cord	L7CN45_C1	4.0e-08
Leo1	GOBP_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Leo1	GOBP_Rna_Polyadenylation	Mouse	Spinal cord	L7CN45_C1	9.6e-06
Leo1	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Leo1	GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Spinal cord	L7CN45_C1	9.0e-07
Leo1	GOBP_Maintenance_Of_Cell_Number	Mouse	Spinal cord	L7CN47_C1	3.9e-06
Leo1	GOBP_Regulation_Of_Mrna_3_End_Processing	Mouse	Spinal cord	L7CN47_C1	2.6e-06
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Spinal cord	L7CN75_C1	1.3e-06
Leo1	GOBP_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Spinal cord	L7CN97_E2	9.8e-07
Leo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Spinal cord	L8CN17_E1	3.7e-07
Leo1	GOBP_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Spinal cord	L8CN17_E1	7.4e-06
Leo1	GOBP_Cell_Fate_Commitment_Involved_In_Formation_Of_Primary_Germ_Layer	Mouse	Brain	rep_21	4.4e-05
Leo1	GOBP_Endoderm_Formation	Mouse	Brain	rep_24	1.7e-05
Leo1	GOBP_Endodermal_Cell_Differentiation	Mouse	Brain	rep_24	8.9e-07
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Brain	rep_27	1.4e-05
Leo1	GOBP_Mrna_3_End_Processing	Mouse	Brain	rep_27	3.0e-05
Leo1	GOBP_Positive_Regulation_Of_Mrna_3_End_Processing	Mouse	Brain	rep_27	1.7e-05
Leo1	GOBP_Protein_Monoubiquitination	Mouse	Brain	rep_27	1.7e-05
Leo1	GOBP_Rna_3_End_Processing	Mouse	Brain	rep_27	4.5e-09
Leo1	GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Brain	rep_27	4.7e-08
Leo1	GOBP_Endoderm_Development	Mouse	Brain	rep_41	3.1e-08
Leo1	GOBP_Positive_Regulation_Of_Mrna_Processing	Mouse	Brain	rep_41	3.4e-09
Leo1	GOBP_Cell_Cell_Signaling	Mouse	Brain	rep_1	5.1e-48
Leo1	GOBP_Chromosome_Organization	Mouse	Brain	rep_1	3.9e-07
Leo1	GOBP_Endodermal_Cell_Differentiation	Mouse	Brain	rep_1	2.8e-07
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Brain	rep_1	5.8e-16
Leo1	GOBP_Histone_Monoubiquitination	Mouse	Brain	rep_1	1.8e-21
Leo1	GOBP_Histone_Ubiquitination	Mouse	Brain	rep_1	5.1e-07
Leo1	GOBP_Mrna_3_End_Processing	Mouse	Brain	rep_1	8.1e-07
Leo1	GOBP_Negative_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Brain	rep_1	2.1e-07
Leo1	GOBP_Positive_Regulation_Of_Mrna_3_End_Processing	Mouse	Brain	rep_1	2.3e-15
Leo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_1	2.5e-12
Leo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	rep_1	1.6e-17
Leo1	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Brain	rep_1	2.3e-15
Leo1	GOBP_Regulation_Of_Mrna_3_End_Processing	Mouse	Brain	rep_1	2.1e-07
Leo1	GOBP_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Brain	rep_1	1.8e-19
Leo1	GOBP_Rna_Polyadenylation	Mouse	Brain	rep_1	4.2e-07
Leo1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	rep_3	5.3e-58
Leo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Brain	rep_3	2.0e-124
Leo1	GOBP_Cell_Fate_Commitment	Mouse	Brain	rep_3	8.8e-182
Leo1	GOBP_Cell_Fate_Commitment_Involved_In_Formation_Of_Primary_Germ_Layer	Mouse	Brain	rep_3	8.6e-125
Leo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Brain	rep_3	3.3e-46
Leo1	GOBP_Chromatin_Organization	Mouse	Brain	rep_3	5.1e-215
Leo1	GOBP_Dna_Templated_Transcription_Elongation	Mouse	Brain	rep_3	5.9e-172
Leo1	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
Leo1	GOBP_Embryonic_Morphogenesis	Mouse	Brain	rep_3	5.0e-165
Leo1	GOBP_Endoderm_Development	Mouse	Brain	rep_3	1.8e-94
Leo1	GOBP_Endoderm_Formation	Mouse	Brain	rep_3	1.8e-53
Leo1	GOBP_Endodermal_Cell_Fate_Commitment	Mouse	Brain	rep_3	9.8e-86
Leo1	GOBP_Formation_Of_Primary_Germ_Layer	Mouse	Brain	rep_3	1.6e-137
Leo1	GOBP_Gastrulation	Mouse	Brain	rep_3	2.3e-75
Leo1	GOBP_Immune_System_Development	Mouse	Brain	rep_3	1.3e-52
Leo1	GOBP_Maintenance_Of_Cell_Number	Mouse	Brain	rep_3	1.7e-143
Leo1	GOBP_Mrna_Metabolic_Process	Mouse	Brain	rep_3	3.9e-221
Leo1	GOBP_Mrna_Processing	Mouse	Brain	rep_3	4.7e-219
Leo1	GOBP_Myeloid_Cell_Differentiation	Mouse	Brain	rep_3	1.8e-21
Leo1	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Brain	rep_3	6.9e-23
Leo1	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Brain	rep_3	3.9e-71
Leo1	GOBP_Positive_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Brain	rep_3	5.7e-146
Leo1	GOBP_Positive_Regulation_Of_Mrna_Metabolic_Process	Mouse	Brain	rep_3	1.1e-164
Leo1	GOBP_Positive_Regulation_Of_Mrna_Processing	Mouse	Brain	rep_3	3.7e-184
Leo1	GOBP_Positive_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Brain	rep_3	1.3e-115
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Brain	rep_3	1.4e-184
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Brain	rep_3	6.3e-190
Leo1	GOBP_Protein_Monoubiquitination	Mouse	Brain	rep_3	5.2e-196
Leo1	GOBP_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Brain	rep_3	6.4e-162
Leo1	GOBP_Regulation_Of_Hemopoiesis	Mouse	Brain	rep_3	2.8e-139
Leo1	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.4e-111
Leo1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Brain	rep_3	9.2e-182
Leo1	GOBP_Regulation_Of_Mrna_Processing	Mouse	Brain	rep_3	4.6e-195
Leo1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Brain	rep_3	5.2e-95
Leo1	GOBP_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Brain	rep_3	1.5e-155
Leo1	GOBP_Rna_3_End_Processing	Mouse	Brain	rep_3	2.2e-166
Leo1	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Leo1	GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Brain	rep_3	1.1e-174
Leo1	GOBP_Gastrulation	Mouse	Embryo	rep_6	5.8e-07
Leo1	GOBP_Histone_Monoubiquitination	Mouse	Embryo	rep_6	3.7e-15
Leo1	GOBP_Histone_Ubiquitination	Mouse	Embryo	rep_6	4.1e-07
Leo1	GOBP_Negative_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Embryo	rep_6	9.2e-18
Leo1	GOBP_Regulation_Of_Hemopoiesis	Mouse	Embryo	rep_6	8.7e-07
Leo1	GOBP_Dna_Templated_Transcription_Elongation	Mouse	Embryo	rep_14	1.0e-14
Leo1	GOBP_Endodermal_Cell_Fate_Commitment	Mouse	Embryo	rep_14	8.1e-12
Leo1	GOBP_Formation_Of_Primary_Germ_Layer	Mouse	Embryo	rep_14	1.1e-10
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Embryo	rep_14	6.4e-37
Leo1	GOBP_Myeloid_Cell_Differentiation	Mouse	Embryo	rep_14	1.3e-11
Leo1	GOBP_Positive_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Embryo	rep_14	5.5e-13
Leo1	GOBP_Positive_Regulation_Of_Mrna_3_End_Processing	Mouse	Embryo	rep_14	2.2e-24
Leo1	GOBP_Positive_Regulation_Of_Mrna_Metabolic_Process	Mouse	Embryo	rep_14	1.8e-19
Leo1	GOBP_Positive_Regulation_Of_Mrna_Processing	Mouse	Embryo	rep_14	8.5e-33
Leo1	GOBP_Positive_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Embryo	rep_14	3.0e-45
Leo1	GOBP_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Embryo	rep_14	7.6e-07
Leo1	GOBP_Regulation_Of_Mrna_3_End_Processing	Mouse	Embryo	rep_14	1.6e-35
Leo1	GOBP_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Embryo	rep_14	1.3e-07
Leo1	GOBP_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Embryo	rep_14	4.1e-18
Leo1	GOBP_Rna_3_End_Processing	Mouse	Embryo	rep_14	4.1e-27
Leo1	GOBP_Rna_Polyadenylation	Mouse	Embryo	rep_14	7.0e-24
Leo1	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Leo1	GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Embryo	rep_14	2.0e-22
Leo1	GOBP_Cell_Fate_Commitment	Mouse	Embryo	rep_1	6.8e-22
Leo1	GOBP_Cell_Fate_Commitment_Involved_In_Formation_Of_Primary_Germ_Layer	Mouse	Embryo	rep_1	3.6e-196
Leo1	GOBP_Dna_Templated_Transcription_Elongation	Mouse	Embryo	rep_1	0.0e+00
Leo1	GOBP_Immune_System_Development	Mouse	Embryo	rep_1	0.0e+00
Leo1	GOBP_Mrna_Metabolic_Process	Mouse	Embryo	rep_1	5.8e-21
Leo1	GOBP_Myeloid_Cell_Differentiation	Mouse	Embryo	rep_1	2.4e-139
Leo1	GOBP_Negative_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Embryo	rep_1	0.0e+00
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Embryo	rep_1	4.4e-16
Leo1	GOBP_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Embryo	rep_1	1.0e-90
Leo1	GOBP_Regulation_Of_Hemopoiesis	Mouse	Embryo	rep_1	0.0e+00
Leo1	GOBP_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	9.5e-143
Leo1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Embryo	rep_1	5.8e-21
Leo1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Embryo	rep_1	2.8e-203
Leo1	GOBP_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Embryo	rep_1	0.0e+00
Leo1	GOBP_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Embryo	rep_1	1.0e-90
Leo1	GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Embryo	rep_1	0.0e+00
Leo1	GOBP_Histone_Monoubiquitination	Mouse	Embryo	rep_2	6.1e-63
Leo1	GOBP_Histone_Ubiquitination	Mouse	Embryo	rep_2	3.0e-194
Leo1	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Embryo	rep_2	7.5e-38
Leo1	GOBP_Protein_Monoubiquitination	Mouse	Embryo	rep_2	6.1e-63
Leo1	GOBP_Rna_3_End_Processing	Mouse	Embryo	rep_2	2.8e-16
Leo1	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Leo1	GOBP_Chromatin_Organization	Mouse	Embryo	rep_3	2.9e-87
Leo1	GOBP_Chromosome_Organization	Mouse	Embryo	rep_3	1.4e-57
Leo1	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
Leo1	GOBP_Positive_Regulation_Of_Mrna_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Leo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_3	0.0e+00
Leo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Embryo	rep_3	0.0e+00
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Embryo	rep_3	4.2e-21
Leo1	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Embryo	rep_3	6.3e-72
Leo1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Embryo	rep_6	3.8e-28
Leo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Embryo	rep_6	1.7e-33
Leo1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Leo1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Kidney	Nep	1.3e-32
Leo1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	rep_2	5.6e-148
Leo1	GOBP_Cell_Cell_Signaling	Mouse	Kidney	rep_2	6.2e-72
Leo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Kidney	rep_2	2.1e-78
Leo1	GOBP_Cell_Fate_Commitment	Mouse	Kidney	rep_2	1.1e-65
Leo1	GOBP_Cell_Fate_Commitment_Involved_In_Formation_Of_Primary_Germ_Layer	Mouse	Kidney	rep_2	2.8e-24
Leo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Kidney	rep_2	6.7e-89
Leo1	GOBP_Chromatin_Organization	Mouse	Kidney	rep_2	3.0e-63
Leo1	GOBP_Chromosome_Organization	Mouse	Kidney	rep_2	1.0e-14
Leo1	GOBP_Dna_Templated_Transcription_Elongation	Mouse	Kidney	rep_2	5.3e-82
Leo1	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
Leo1	GOBP_Embryonic_Morphogenesis	Mouse	Kidney	rep_2	7.3e-66
Leo1	GOBP_Endoderm_Development	Mouse	Kidney	rep_2	3.0e-25
Leo1	GOBP_Endoderm_Formation	Mouse	Kidney	rep_2	9.1e-50
Leo1	GOBP_Endodermal_Cell_Differentiation	Mouse	Kidney	rep_2	6.2e-72
Leo1	GOBP_Endodermal_Cell_Fate_Commitment	Mouse	Kidney	rep_2	1.0e-55
Leo1	GOBP_Formation_Of_Primary_Germ_Layer	Mouse	Kidney	rep_2	2.0e-41
Leo1	GOBP_Gastrulation	Mouse	Kidney	rep_2	2.6e-89
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Kidney	rep_2	2.8e-62
Leo1	GOBP_Histone_Monoubiquitination	Mouse	Kidney	rep_2	1.3e-34
Leo1	GOBP_Histone_Ubiquitination	Mouse	Kidney	rep_2	2.6e-94
Leo1	GOBP_Immune_System_Development	Mouse	Kidney	rep_2	4.6e-22
Leo1	GOBP_Maintenance_Of_Cell_Number	Mouse	Kidney	rep_2	2.5e-69
Leo1	GOBP_Mrna_3_End_Processing	Mouse	Kidney	rep_2	2.0e-28
Leo1	GOBP_Mrna_Metabolic_Process	Mouse	Kidney	rep_2	3.1e-08
Leo1	GOBP_Mrna_Processing	Mouse	Kidney	rep_2	5.0e-53
Leo1	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Kidney	rep_2	1.0e-68
Leo1	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Kidney	rep_2	4.6e-113
Leo1	GOBP_Negative_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Kidney	rep_2	2.5e-17
Leo1	GOBP_Positive_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Kidney	rep_2	1.5e-39
Leo1	GOBP_Positive_Regulation_Of_Mrna_3_End_Processing	Mouse	Kidney	rep_2	3.0e-17
Leo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	4.5e-10
Leo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Kidney	rep_2	8.3e-40
Leo1	GOBP_Protein_Monoubiquitination	Mouse	Kidney	rep_2	5.7e-37
Leo1	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Kidney	rep_2	2.6e-14
Leo1	GOBP_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Kidney	rep_2	3.9e-45
Leo1	GOBP_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	2.5e-84
Leo1	GOBP_Regulation_Of_Mrna_3_End_Processing	Mouse	Kidney	rep_2	4.4e-33
Leo1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Kidney	rep_2	1.1e-20
Leo1	GOBP_Regulation_Of_Mrna_Processing	Mouse	Kidney	rep_2	2.1e-13
Leo1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Kidney	rep_2	8.2e-110
Leo1	GOBP_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Kidney	rep_2	3.0e-31
Leo1	GOBP_Rna_3_End_Processing	Mouse	Kidney	rep_2	2.8e-70
Leo1	GOBP_Rna_Polyadenylation	Mouse	Kidney	rep_2	5.4e-41
Leo1	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Leo1	GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Kidney	rep_2	3.3e-51
Leo1	GOBP_Dna_Templated_Transcription_Elongation	Mouse	Liver	CN16-D2	6.9e-09
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Liver	CN16-D2	9.7e-08
Leo1	GOBP_Histone_Monoubiquitination	Mouse	Liver	CN16-D2	2.0e-11
Leo1	GOBP_Mrna_Metabolic_Process	Mouse	Liver	CN16-D2	5.2e-07
Leo1	GOBP_Mrna_Processing	Mouse	Liver	CN16-D2	4.8e-09
Leo1	GOBP_Negative_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Liver	CN16-D2	2.2e-09
Leo1	GOBP_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Liver	CN16-D2	1.7e-08
Leo1	GOBP_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Liver	CN16-D2	2.7e-08
Leo1	GOBP_Positive_Regulation_Of_Mrna_Processing	Mouse	Liver	CN16-E1	1.8e-08
Leo1	GOBP_Rna_Polyadenylation	Mouse	Liver	CN16-E1	2.6e-07
Leo1	GOBP_Positive_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Liver	CN65-C1	6.9e-10
Leo1	GOBP_Immune_System_Development	Mouse	Liver	CN73-C1	2.2e-07
Leo1	GOBP_Cell_Fate_Commitment_Involved_In_Formation_Of_Primary_Germ_Layer	Mouse	Liver	rep_15	1.0e-08
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Liver	rep_15	3.1e-12
Leo1	GOBP_Endodermal_Cell_Fate_Commitment	Mouse	Liver	rep_16	3.3e-15
Leo1	GOBP_Histone_Ubiquitination	Mouse	Liver	rep_16	6.7e-12
Leo1	GOBP_Immune_System_Development	Mouse	Liver	rep_16	5.3e-11
Leo1	GOBP_Positive_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Liver	rep_16	3.1e-10
Leo1	GOBP_Positive_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Liver	rep_16	2.9e-08
Leo1	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Liver	rep_16	3.6e-08
Leo1	GOBP_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Liver	rep_16	5.7e-07
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Brain	rep_1	4.9e-05
Leo1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Lymph	MS-1	6.4e-13
Leo1	GOBP_Cell_Cell_Signaling	Mouse	Lymph	MS-1	9.7e-11
Leo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Lymph	MS-1	7.3e-10
Leo1	GOBP_Cell_Fate_Commitment	Mouse	Lymph	MS-1	2.1e-11
Leo1	GOBP_Cell_Fate_Commitment_Involved_In_Formation_Of_Primary_Germ_Layer	Mouse	Lymph	MS-1	3.0e-11
Leo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Lymph	MS-1	1.6e-11
Leo1	GOBP_Chromatin_Organization	Mouse	Lymph	MS-1	9.1e-11
Leo1	GOBP_Chromosome_Organization	Mouse	Lymph	MS-1	3.5e-09
Leo1	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
Leo1	GOBP_Embryonic_Morphogenesis	Mouse	Lymph	MS-1	5.6e-07
Leo1	GOBP_Endoderm_Development	Mouse	Lymph	MS-1	1.5e-08
Leo1	GOBP_Endoderm_Formation	Mouse	Lymph	MS-1	1.1e-09
Leo1	GOBP_Endodermal_Cell_Differentiation	Mouse	Lymph	MS-1	2.3e-07
Leo1	GOBP_Formation_Of_Primary_Germ_Layer	Mouse	Lymph	MS-1	1.3e-08
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Lymph	MS-1	4.8e-08
Leo1	GOBP_Histone_Ubiquitination	Mouse	Lymph	MS-1	1.3e-07
Leo1	GOBP_Immune_System_Development	Mouse	Lymph	MS-1	1.2e-13
Leo1	GOBP_Maintenance_Of_Cell_Number	Mouse	Lymph	MS-1	7.2e-10
Leo1	GOBP_Mrna_3_End_Processing	Mouse	Lymph	MS-1	2.6e-07
Leo1	GOBP_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	3.2e-11
Leo1	GOBP_Myeloid_Cell_Differentiation	Mouse	Lymph	MS-1	1.9e-13
Leo1	GOBP_Negative_Regulation_Of_Cell_Differentiation	Mouse	Lymph	MS-1	2.2e-14
Leo1	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Lymph	MS-1	4.0e-14
Leo1	GOBP_Negative_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Lymph	MS-1	5.1e-10
Leo1	GOBP_Positive_Regulation_Of_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	4.8e-07
Leo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Leo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Lymph	MS-1	1.7e-12
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Lymph	MS-1	1.4e-09
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Lymph	MS-1	1.4e-09
Leo1	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Lymph	MS-1	1.3e-14
Leo1	GOBP_Regulation_Of_Hemopoiesis	Mouse	Lymph	MS-1	1.7e-14
Leo1	GOBP_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	2.2e-14
Leo1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	3.3e-08
Leo1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Lymph	MS-1	7.2e-15
Leo1	GOBP_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Lymph	MS-1	4.7e-18
Leo1	GOBP_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Lymph	MS-1	2.9e-07
Leo1	GOBP_Rna_3_End_Processing	Mouse	Lymph	MS-1	1.5e-11
Leo1	GOBP_Rna_Polyadenylation	Mouse	Lymph	MS-1	1.0e-12
Leo1	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Leo1	GOBP_Gastrulation	Mouse	Lymph	MS-2	2.0e-07
Leo1	GOBP_Regulation_Of_Mrna_3_End_Processing	Mouse	Lymph	MS-2	1.8e-09
Leo1	GOBP_Endodermal_Cell_Differentiation	Mouse	Brain	rep_4	8.2e-10
Leo1	GOBP_Formation_Of_Primary_Germ_Layer	Mouse	Brain	rep_4	3.1e-21
Leo1	GOBP_Endoderm_Formation	Mouse	Brain	rep_7	6.4e-08
Leo1	GOBP_Endoderm_Formation	Mouse	Brain	HP_ad_rep3	8.6e-08
Leo1	GOBP_Endodermal_Cell_Differentiation	Mouse	Brain	HP_ad_rep3	3.4e-08
Leo1	GOBP_Cell_Cell_Signaling	Mouse	Brain	HP_ad_rep7	1.6e-08
Leo1	GOBP_Cell_Fate_Commitment	Mouse	Brain	HP_ad_rep7	1.5e-09
Leo1	GOBP_Chromatin_Organization	Mouse	Brain	HP_ad_rep7	7.6e-11
Leo1	GOBP_Chromosome_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Leo1	GOBP_Dna_Templated_Transcription_Elongation	Mouse	Brain	HP_ad_rep7	1.4e-14
Leo1	GOBP_Endoderm_Development	Mouse	Brain	HP_ad_rep7	1.3e-07
Leo1	GOBP_Histone_H2b_Ubiquitination	Mouse	Brain	HP_ad_rep7	1.9e-09
Leo1	GOBP_Histone_Ubiquitination	Mouse	Brain	HP_ad_rep7	3.1e-12
Leo1	GOBP_Immune_System_Development	Mouse	Brain	HP_ad_rep7	8.3e-09
Leo1	GOBP_Maintenance_Of_Cell_Number	Mouse	Brain	HP_ad_rep7	1.6e-11
Leo1	GOBP_Mrna_3_End_Processing	Mouse	Brain	HP_ad_rep7	3.7e-18
Leo1	GOBP_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-09
Leo1	GOBP_Mrna_Processing	Mouse	Brain	HP_ad_rep7	2.3e-09
Leo1	GOBP_Myeloid_Cell_Differentiation	Mouse	Brain	HP_ad_rep7	1.2e-09
Leo1	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Brain	HP_ad_rep7	1.7e-11
Leo1	GOBP_Negative_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Brain	HP_ad_rep7	6.6e-08
Leo1	GOBP_Positive_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Brain	HP_ad_rep7	1.1e-11
Leo1	GOBP_Positive_Regulation_Of_Mrna_3_End_Processing	Mouse	Brain	HP_ad_rep7	1.9e-22
Leo1	GOBP_Positive_Regulation_Of_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.4e-09
Leo1	GOBP_Positive_Regulation_Of_Mrna_Processing	Mouse	Brain	HP_ad_rep7	7.3e-11
Leo1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-11
Leo1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Mouse	Brain	HP_ad_rep7	7.3e-11
Leo1	GOBP_Positive_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Brain	HP_ad_rep7	1.2e-10
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation	Mouse	Brain	HP_ad_rep7	1.7e-09
Leo1	GOBP_Protein_Modification_By_Small_Protein_Conjugation_Or_Removal	Mouse	Brain	HP_ad_rep7	6.9e-09
Leo1	GOBP_Protein_Monoubiquitination	Mouse	Brain	HP_ad_rep7	3.3e-07
Leo1	GOBP_Regulation_Of_Dna_Templated_Transcription_Elongation	Mouse	Brain	HP_ad_rep7	6.7e-10
Leo1	GOBP_Regulation_Of_Hemopoiesis	Mouse	Brain	HP_ad_rep7	2.0e-08
Leo1	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	1.8e-09
Leo1	GOBP_Regulation_Of_Mrna_3_End_Processing	Mouse	Brain	HP_ad_rep7	2.9e-11
Leo1	GOBP_Regulation_Of_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	9.2e-08
Leo1	GOBP_Regulation_Of_Mrna_Processing	Mouse	Brain	HP_ad_rep7	2.2e-11
Leo1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Brain	HP_ad_rep7	1.1e-08
Leo1	GOBP_Regulation_Of_Myeloid_Cell_Differentiation	Mouse	Brain	HP_ad_rep7	4.4e-11
Leo1	GOBP_Regulation_Of_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Brain	HP_ad_rep7	1.6e-12
Leo1	GOBP_Rna_3_End_Processing	Mouse	Brain	HP_ad_rep7	1.1e-14
Leo1	GOBP_Rna_Polyadenylation	Mouse	Brain	HP_ad_rep7	1.6e-11
Leo1	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Leo1	GOBP_Transcription_Elongation_From_Rna_Polymerase_Ii_Promoter	Mouse	Brain	HP_ad_rep7	9.4e-09
Leo1	GOBP_Formation_Of_Primary_Germ_Layer	Mouse	Brain	HP_adpolb_rep1	1.4e-09
Leo1	GOBP_Cell_Fate_Commitment_Involved_In_Formation_Of_Primary_Germ_Layer	Mouse	Brain	HP_adpolb_rep3	4.4e-07
Leo1	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	HP_polb_rep9	6.3e-08
Leo1	GOBP_Cell_Cell_Signaling_By_Wnt	Mouse	Brain	HP_polb_rep9	1.7e-14
Leo1	GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_Signaling	Mouse	Brain	HP_polb_rep9	1.2e-14
Leo1	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
Leo1	GOBP_Embryonic_Morphogenesis	Mouse	Brain	HP_polb_rep9	3.7e-09
Leo1	GOBP_Histone_Monoubiquitination	Mouse	Brain	HP_polb_rep9	2.2e-11
Leo1	GOBP_Regulation_Of_Cell_Differentiation	Mouse	Brain	HP_polb_rep9	6.5e-09

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Leo1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Leo1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Leo1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Leo1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Leo1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source