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Spatial pattern gene: Creb5 (spascer ID:231991) |
Gene summary for Creb5 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Creb5 | Gene ID | 231991 |
| Gene name | cAMP responsive element binding protein 5 |
| Synonyms | 9430076C15Rik|CRE-BPa|Crebpa|D430026C09Rik |
| Cytomap | 6 B3|6 25.9 cM |
| Type of gene | protein-coding |
| Description | cyclic AMP-responsive element-binding protein 5 |
| Modification date | 20220424 |
| UniProtAcc | Q8K1L0 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Creb5 | GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding | 21873635 | Function |
| Creb5 | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | 21873635 | Function |
| Creb5 | GO:0006357 | regulation of transcription by RNA polymerase II | 21873635 | Process |
| Creb5 | GO:0035497 | cAMP response element binding | 21873635 | Function |
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Spatial pattern events for Creb5 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Creb5 | Mouse | Brain | S2 | 34413515 | 2.85e-15 |
| Creb5 | Mouse | Brain | S4 | 34413515 | 4.65e-15 |
| Creb5 | Mouse | Brain | S6 | 34413515 | 5.07e-15 |
| Creb5 | Mouse | Brain | S7 | 34413515 | 1.55e-15 |
| Creb5 | Mouse | Embryo | 1D | 34210887 | 5.56e-07 |
| Creb5 | Mouse | Embryo | 1E | 34210887 | 6.22e-09 |
| Creb5 | Mouse | Embryo | 1F | 34210887 | 1.21e-10 |
| Creb5 | Mouse | Embryo | 1G | 34210887 | 6.15e-15 |
| Creb5 | Mouse | Embryo | 2H | 34210887 | 5.16e-11 |
| Creb5 | Mouse | Embryo | 3D | 34210887 | 6.89e-07 |
| Creb5 | Mouse | Embryo | 3G | 34210887 | 6.05e-08 |
| Creb5 | Mouse | Embryo | 4D | 34210887 | 1.42e-06 |
| Creb5 | Mouse | Embryo | 4E | 34210887 | 4.53e-15 |
| Creb5 | Mouse | Testicle | rep_4 | 34731600 | 1.29e-13 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
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Spatial pattern pathway has Creb5 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Creb5 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | rep_1 | 2.5e-12 |
| Creb5 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Embryo | rep_3 | 0.0e+00 |
| Creb5 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Kidney | rep_2 | 4.5e-10 |
| Creb5 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Lymph | MS-1 | 4.4e-12 |
| Creb5 | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-11 |
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Creb5 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Creb5 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Creb5 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Creb5 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Creb5 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Creb5 | C0004238 | Atrial Fibrillation | 2 | CTD_human |
| Creb5 | C0235480 | Paroxysmal atrial fibrillation | 2 | CTD_human |
| Creb5 | C2585653 | Persistent atrial fibrillation | 2 | CTD_human |
| Creb5 | C3468561 | familial atrial fibrillation | 2 | CTD_human |
| Creb5 | C0000809 | Abortion, Habitual | 1 | CTD_human |
