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Spatial pattern gene: Slc16a4 (spascer ID:229699) |
Gene summary for Slc16a4 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Slc16a4 | Gene ID | 229699 |
| Gene name | solute carrier family 16 (monocarboxylic acid transporters), member 4 |
| Synonyms | AW146050|MCT 5 |
| Cytomap | 3|3 F2.3 |
| Type of gene | protein-coding |
| Description | monocarboxylate transporter 5 |
| Modification date | 20220424 |
| UniProtAcc | Q8R0M8 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Slc16a4 | GO:0005887 | integral component of plasma membrane | 21873635 | Component |
| Slc16a4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity | 21873635 | Function |
| Slc16a4 | GO:0015718 | monocarboxylic acid transport | 21873635 | Process |
| Slc16a4 | GO:0016021 | integral component of membrane | 21873635 | Component |
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Spatial pattern events for Slc16a4 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Slc16a4 | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Slc16a4 | Mouse | Kidney | IRI | 34003797 | 3.92e-15 |
| Slc16a4 | Mouse | Kidney | Sham | 34003797 | 2.58e-15 |
| Slc16a4 | Mouse | Kidney | rep_1 | 34853151 | 2.42e-15 |
| Slc16a4 | Mouse | Kidney | rep_3 | 34853151 | 2.94e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_3_H&E  |  |
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Spatial pattern pathway has Slc16a4 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Slc16a4 | GOBP_Carboxylic_Acid_Transport | Mouse | Spinal cord | L7bCN02_E1 | 9.0e-06 |
| Slc16a4 | GOBP_Monocarboxylic_Acid_Transport | Mouse | Spinal cord | L7CN45_C1 | 8.4e-09 |
| Slc16a4 | GOBP_Organic_Anion_Transport | Mouse | Spinal cord | L7CN45_C1 | 9.2e-06 |
| Slc16a4 | GOBP_Transmembrane_Transport | Mouse | Spinal cord | L7CN45_C1 | 3.5e-08 |
| Slc16a4 | GOBP_Transmembrane_Transport | Mouse | Brain | rep_1 | 3.1e-23 |
| Slc16a4 | GOBP_Organic_Anion_Transport | Mouse | Brain | rep_3 | 1.5e-10 |
| Slc16a4 | GOBP_Carboxylic_Acid_Transport | Mouse | Brain | rep_7 | 1.4e-34 |
| Slc16a4 | GOBP_Carboxylic_Acid_Transport | Mouse | Embryo | rep_14 | 2.3e-35 |
| Slc16a4 | GOBP_Monocarboxylic_Acid_Transport | Mouse | Embryo | rep_14 | 8.5e-25 |
| Slc16a4 | GOBP_Organic_Anion_Transport | Mouse | Embryo | rep_14 | 5.6e-22 |
| Slc16a4 | GOBP_Monocarboxylic_Acid_Transport | Mouse | Embryo | rep_1 | 7.1e-54 |
| Slc16a4 | GOBP_Carboxylic_Acid_Transport | Mouse | Embryo | rep_2 | 2.0e-146 |
| Slc16a4 | GOBP_Organic_Anion_Transport | Mouse | Embryo | rep_2 | 6.5e-51 |
| Slc16a4 | GOBP_Transmembrane_Transport | Mouse | Kidney | Nep | 4.2e-26 |
| Slc16a4 | GOBP_Carboxylic_Acid_Transport | Mouse | Kidney | rep_2 | 5.6e-40 |
| Slc16a4 | GOBP_Monocarboxylic_Acid_Transport | Mouse | Kidney | rep_2 | 1.9e-22 |
| Slc16a4 | GOBP_Organic_Anion_Transport | Mouse | Kidney | rep_2 | 1.5e-34 |
| Slc16a4 | GOBP_Transmembrane_Transport | Mouse | Kidney | rep_2 | 2.7e-23 |
| Slc16a4 | GOBP_Transmembrane_Transport | Mouse | Liver | rep_16 | 1.4e-13 |
| Slc16a4 | GOBP_Carboxylic_Acid_Transport | Mouse | Lymph | MS-1 | 1.1e-07 |
| Slc16a4 | GOBP_Monocarboxylic_Acid_Transport | Mouse | Lymph | MS-1 | 4.3e-13 |
| Slc16a4 | GOBP_Organic_Anion_Transport | Mouse | Lymph | MS-1 | 1.6e-07 |
| Slc16a4 | GOBP_Carboxylic_Acid_Transport | Mouse | Brain | rep_4 | 1.4e-14 |
| Slc16a4 | GOBP_Organic_Anion_Transport | Mouse | Brain | rep_4 | 3.4e-08 |
| Slc16a4 | GOBP_Organic_Anion_Transport | Mouse | Brain | HP_ad_rep7 | 1.4e-08 |
| Slc16a4 | GOBP_Transmembrane_Transport | Mouse | Brain | HP_ad_rep7 | 3.4e-07 |
| Slc16a4 | GOBP_Carboxylic_Acid_Transport | Mouse | Brain | HP_adpolb_rep1 | 1.6e-08 |
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Slc16a4 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Slc16a4 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Slc16a4 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Slc16a4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Slc16a4 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
