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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

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Spatial pattern pathway

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Cell cell interactions using single cell data

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Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Arhgap11a (spascer ID:228482)

Gene summary for Arhgap11a

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Arhgap11a

Gene ID

228482

Gene nameRho GTPase activating protein 11A
Synonyms6530401L14Rik|mKIAA0013
Cytomap2|2 E4
Type of geneprotein-coding
Descriptionrho GTPase-activating protein 11AGAP (1-12)rho-type GTPase-activating protein 11A
Modification date20220424
UniProtAcc

Q80Y19


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Arhgap11a

GO:0005096

GTPase activator activity

21873635

Function

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Spatial pattern events for Arhgap11a

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Arhgap11aMouseEmbryorep_2 331887761.02e-06
Arhgap11aMouseKidneyrep_5 348531513.48e-13
Arhgap11aMouseBrainrep_1 334690251.30e-15
Arhgap11aMouseIntestinerep_4 351497213.12e-07
Arhgap11aMouseTesticlerep_6 347316005.03e-08
Arhgap11aMouseLymphA1 09.40e-13
Arhgap11aMouseLymphB1 03.66e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_rep_5_H&E
boxplot

boxplot
Brain_rep_1_H&E
boxplot


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Spatial pattern pathway has Arhgap11a envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Arhgap11aGOBP_Positive_Regulation_Of_Catalytic_ActivityMouseSpinal cordL7CN45_C1 3.2e-07
Arhgap11aGOBP_Positive_Regulation_Of_Gtpase_ActivityMouseSpinal cordL7CN45_C1 7.5e-06
Arhgap11aGOBP_Positive_Regulation_Of_Hydrolase_ActivityMouseSpinal cordL7CN45_C1 1.8e-08
Arhgap11aGOBP_Positive_Regulation_Of_Molecular_FunctionMouseSpinal cordL7CN45_C1 3.2e-07
Arhgap11aGOBP_Regulation_Of_Hydrolase_ActivityMouseSpinal cordL7CN45_C1 2.3e-07
Arhgap11aGOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_TransductionMouseSpinal cordL7CN45_C1 5.6e-06
Arhgap11aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseSpinal cordL8CN11_D1 5.6e-09
Arhgap11aGOBP_Regulation_Of_Gtpase_ActivityMouseBrainrep_27 4.2e-05
Arhgap11aGOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_TransductionMouseBrainrep_27 6.4e-05
Arhgap11aGOBP_Positive_Regulation_Of_Gtpase_ActivityMouseBrainrep_1 2.1e-36
Arhgap11aGOBP_Positive_Regulation_Of_Hydrolase_ActivityMouseBrainrep_1 1.0e-11
Arhgap11aGOBP_Regulation_Of_Gtpase_ActivityMouseBrainrep_1 5.6e-32
Arhgap11aGOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_TransductionMouseBrainrep_1 5.2e-13
Arhgap11aGOBP_Small_Gtpase_Mediated_Signal_TransductionMouseBrainrep_1 5.1e-22
Arhgap11aGOBP_Positive_Regulation_Of_Catalytic_ActivityMouseBrainrep_3 8.5e-79
Arhgap11aGOBP_Positive_Regulation_Of_Molecular_FunctionMouseBrainrep_3 2.6e-94
Arhgap11aGOBP_Regulation_Of_Hydrolase_ActivityMouseBrainrep_31.4e-120
Arhgap11aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseBrainrep_31.3e-132
Arhgap11aGOBP_Regulation_Of_Hydrolase_ActivityMouseEmbryorep_14 8.5e-07
Arhgap11aGOBP_Positive_Regulation_Of_Catalytic_ActivityMouseEmbryorep_1 2.2e-98
Arhgap11aGOBP_Positive_Regulation_Of_Hydrolase_ActivityMouseEmbryorep_1 1.6e-15
Arhgap11aGOBP_Small_Gtpase_Mediated_Signal_TransductionMouseEmbryorep_3 5.2e-68
Arhgap11aGOBP_Positive_Regulation_Of_Catalytic_ActivityMouseKidneyNep 1.8e-46
Arhgap11aGOBP_Positive_Regulation_Of_Hydrolase_ActivityMouseKidneyNep 1.4e-48
Arhgap11aGOBP_Positive_Regulation_Of_Molecular_FunctionMouseKidneyNep 1.8e-46
Arhgap11aGOBP_Regulation_Of_Hydrolase_ActivityMouseKidneyNep 1.3e-36
Arhgap11aGOBP_Positive_Regulation_Of_Catalytic_ActivityMouseKidneyrep_2 2.1e-66
Arhgap11aGOBP_Positive_Regulation_Of_Gtpase_ActivityMouseKidneyrep_2 2.1e-81
Arhgap11aGOBP_Positive_Regulation_Of_Hydrolase_ActivityMouseKidneyrep_2 3.6e-50
Arhgap11aGOBP_Positive_Regulation_Of_Molecular_FunctionMouseKidneyrep_2 2.2e-45
Arhgap11aGOBP_Regulation_Of_Gtpase_ActivityMouseKidneyrep_2 1.2e-71
Arhgap11aGOBP_Regulation_Of_Hydrolase_ActivityMouseKidneyrep_2 1.4e-60
Arhgap11aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseKidneyrep_2 1.4e-17
Arhgap11aGOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_TransductionMouseKidneyrep_2 1.0e-93
Arhgap11aGOBP_Small_Gtpase_Mediated_Signal_TransductionMouseKidneyrep_2 1.2e-75
Arhgap11aGOBP_Regulation_Of_Gtpase_ActivityMouseLiverCN16-D2 1.9e-10
Arhgap11aGOBP_Small_Gtpase_Mediated_Signal_TransductionMouseLiverCN16-D2 1.3e-07
Arhgap11aGOBP_Positive_Regulation_Of_Catalytic_ActivityMouseLymphMS-1 2.2e-13
Arhgap11aGOBP_Positive_Regulation_Of_Molecular_FunctionMouseLymphMS-1 1.9e-12
Arhgap11aGOBP_Regulation_Of_Hydrolase_ActivityMouseLymphMS-1 1.9e-08
Arhgap11aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseLymphMS-1 1.0e-14
Arhgap11aGOBP_Small_Gtpase_Mediated_Signal_TransductionMouseLymphMS-1 3.5e-10
Arhgap11aGOBP_Positive_Regulation_Of_Gtpase_ActivityMouseBrainrep_4 7.8e-12
Arhgap11aGOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_TransductionMouseBrainrep_4 6.8e-16
Arhgap11aGOBP_Positive_Regulation_Of_Catalytic_ActivityMouseBrainHP_ad_rep7 2.8e-07
Arhgap11aGOBP_Positive_Regulation_Of_Hydrolase_ActivityMouseBrainHP_ad_rep7 4.8e-07
Arhgap11aGOBP_Positive_Regulation_Of_Molecular_FunctionMouseBrainHP_ad_rep7 2.8e-07
Arhgap11aGOBP_Small_Gtpase_Mediated_Signal_TransductionMouseBrainHP_ad_rep7 4.6e-08
Arhgap11aGOBP_Regulation_Of_Gtpase_ActivityMouseBrainHP_polb_rep9 4.2e-09
Arhgap11aGOBP_Regulation_Of_Hydrolase_ActivityMouseBrainHP_polb_rep9 6.0e-09
Arhgap11aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseBrainHP_polb_rep9 3.9e-11
Arhgap11aGOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_TransductionMouseBrainHP_polb_rep9 5.2e-07
Arhgap11aGOBP_Positive_Regulation_Of_Gtpase_ActivityMouseBrainHP_wt_rep2 2.1e-07

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Arhgap11a function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Arhgap11a function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Arhgap11a envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Arhgap11a

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Arhgap11a

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Arhgap11aC2239176Liver carcinoma1CTD_human