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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Large2 (spascer ID:228366)

Gene summary for Large2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Large2
	Gene ID	228366
	Gene name	LARGE xylosyl- and glucuronyltransferase 2
	Synonyms	5730485C17Rik\|AI891893\|Gyltl1b\|Largel\|mKIAA4105
	Cytomap	2\|2 E1
	Type of gene	protein-coding
	Description	xylosyl- and glucuronyltransferase LARGE2LARGE xylosyl- and glucuronyltransferase 2glycoslytransferase-like 1Bglycosyltransferase-like 1Bglycosyltransferase-like protein LARGE2
	Modification date	20220424
	UniProtAcc	Q5XPT3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Large2	GO:0005794	Golgi apparatus	21873635	Component
Large2	GO:0015020	glucuronosyltransferase activity	21873635	Function
Large2	GO:0035269	protein O-linked mannosylation	21873635	Process
Large2	GO:0042285	xylosyltransferase activity	21873635	Function

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Spatial pattern events for Large2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Large2	Mouse	Kidney	CLP	34003797	2.19e-15
Large2	Mouse	Kidney	Sham	34003797	2.58e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_Sham_H&E

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Spatial pattern pathway has Large2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Large2	GOBP_Muscle_Cell_Cellular_Homeostasis	Mouse	Spinal cord	CN93_D2	9.4e-08
Large2	GOBP_Anatomical_Structure_Homeostasis	Mouse	Spinal cord	CN94_E1	6.4e-06
Large2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Spinal cord	CN94_E1	3.5e-06
Large2	GOBP_Mannosylation	Mouse	Spinal cord	CN94_E1	9.9e-06
Large2	GOBP_Protein_Mannosylation	Mouse	Spinal cord	CN94_E1	2.5e-08
Large2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Spinal cord	L7bCN01_D2	9.0e-06
Large2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Large2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Large2	GOBP_Cellular_Homeostasis	Mouse	Spinal cord	L7CN45_C1	5.7e-08
Large2	GOBP_Glycosylation	Mouse	Spinal cord	L7CN45_C1	8.2e-08
Large2	GOBP_Homeostatic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Large2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Large2	GOBP_Protein_O_Linked_Glycosylation	Mouse	Spinal cord	L7CN45_C1	3.4e-06
Large2	GOBP_Protein_O_Linked_Mannosylation	Mouse	Spinal cord	L7CN45_C1	3.2e-06
Large2	GOBP_Protein_O_Linked_Mannosylation	Mouse	Brain	rep_19	2.5e-07
Large2	GOBP_Mannosylation	Mouse	Brain	rep_41	4.3e-06
Large2	GOBP_Protein_Mannosylation	Mouse	Brain	rep_41	9.3e-07
Large2	GOBP_Cellular_Homeostasis	Mouse	Brain	rep_71	6.9e-06
Large2	GOBP_Mannosylation	Mouse	Brain	rep_1	3.7e-14
Large2	GOBP_Protein_Mannosylation	Mouse	Brain	rep_1	3.6e-28
Large2	GOBP_Protein_O_Linked_Mannosylation	Mouse	Brain	rep_1	1.6e-44
Large2	GOBP_Anatomical_Structure_Homeostasis	Mouse	Brain	rep_3	1.8e-76
Large2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Brain	rep_3	2.7e-27
Large2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Large2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Brain	rep_3	6.4e-155
Large2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Brain	rep_3	1.9e-173
Large2	GOBP_Glycosylation	Mouse	Brain	rep_3	1.2e-150
Large2	GOBP_Muscle_Cell_Cellular_Homeostasis	Mouse	Brain	rep_3	5.1e-135
Large2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Large2	GOBP_Protein_O_Linked_Glycosylation	Mouse	Brain	rep_3	4.3e-204
Large2	GOBP_Homeostatic_Process	Mouse	Brain	rep_7	2.5e-13
Large2	GOBP_Muscle_Cell_Cellular_Homeostasis	Mouse	Embryo	rep_6	4.4e-17
Large2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Embryo	rep_14	4.5e-09
Large2	GOBP_Mannosylation	Mouse	Embryo	rep_14	5.0e-30
Large2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Large2	GOBP_Protein_Mannosylation	Mouse	Embryo	rep_14	1.7e-21
Large2	GOBP_Protein_O_Linked_Glycosylation	Mouse	Embryo	rep_14	1.6e-23
Large2	GOBP_Protein_O_Linked_Mannosylation	Mouse	Embryo	rep_14	1.5e-09
Large2	GOBP_Homeostatic_Process	Mouse	Embryo	rep_1	2.0e-30
Large2	GOBP_Glycosylation	Mouse	Embryo	rep_3	2.6e-64
Large2	GOBP_Protein_O_Linked_Glycosylation	Mouse	Embryo	rep_3	2.6e-64
Large2	GOBP_Anatomical_Structure_Homeostasis	Mouse	Kidney	rep_2	8.4e-22
Large2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Kidney	rep_2	1.3e-08
Large2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Large2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Kidney	rep_2	2.5e-89
Large2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Kidney	rep_2	1.1e-102
Large2	GOBP_Glycosylation	Mouse	Kidney	rep_2	5.3e-81
Large2	GOBP_Homeostatic_Process	Mouse	Kidney	rep_2	2.2e-10
Large2	GOBP_Mannosylation	Mouse	Kidney	rep_2	5.8e-67
Large2	GOBP_Muscle_Cell_Cellular_Homeostasis	Mouse	Kidney	rep_2	3.0e-66
Large2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Large2	GOBP_Protein_Mannosylation	Mouse	Kidney	rep_2	3.6e-56
Large2	GOBP_Protein_O_Linked_Glycosylation	Mouse	Kidney	rep_2	3.5e-72
Large2	GOBP_Protein_O_Linked_Mannosylation	Mouse	Kidney	rep_2	4.1e-34
Large2	GOBP_Muscle_Cell_Cellular_Homeostasis	Mouse	Liver	CN16-D1	1.4e-17
Large2	GOBP_Protein_O_Linked_Mannosylation	Mouse	Liver	CN65-C1	1.3e-09
Large2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Liver	CN73-C1	3.2e-07
Large2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Large2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Liver	CN73-C1	9.7e-08
Large2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Liver	CN73-C1	1.4e-07
Large2	GOBP_Glycosylation	Mouse	Liver	CN73-C1	2.0e-07
Large2	GOBP_Mannosylation	Mouse	Liver	CN73-C1	1.4e-07
Large2	GOBP_Protein_Mannosylation	Mouse	Liver	rep_15	6.9e-07
Large2	GOBP_Anatomical_Structure_Homeostasis	Mouse	Liver	rep_16	8.1e-23
Large2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Liver	rep_16	2.6e-08
Large2	GOBP_Protein_O_Linked_Mannosylation	Mouse	Liver	rep_23	5.3e-08
Large2	GOBP_Anatomical_Structure_Homeostasis	Mouse	Lymph	MS-1	1.1e-14
Large2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Large2	GOBP_Cellular_Homeostasis	Mouse	Lymph	MS-1	8.2e-11
Large2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Lymph	MS-1	4.4e-07
Large2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Lymph	MS-1	1.1e-07
Large2	GOBP_Glycosylation	Mouse	Lymph	MS-1	4.8e-08
Large2	GOBP_Homeostatic_Process	Mouse	Lymph	MS-1	2.3e-12
Large2	GOBP_Mannosylation	Mouse	Lymph	MS-1	2.0e-09
Large2	GOBP_Muscle_Cell_Cellular_Homeostasis	Mouse	Lymph	MS-1	1.4e-09
Large2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Large2	GOBP_Protein_Mannosylation	Mouse	Lymph	MS-1	3.8e-11
Large2	GOBP_Muscle_Cell_Cellular_Homeostasis	Mouse	Brain	rep_4	1.4e-19
Large2	GOBP_Protein_O_Linked_Mannosylation	Mouse	Brain	rep_4	1.1e-15
Large2	GOBP_Protein_O_Linked_Mannosylation	Mouse	Brain	HP_ad_rep3	2.3e-07
Large2	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	9.8e-07
Large2	GOBP_Glycosylation	Mouse	Brain	HP_ad_rep7	3.3e-08
Large2	GOBP_Mannosylation	Mouse	Brain	HP_ad_rep7	1.6e-14
Large2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Large2	GOBP_Protein_Mannosylation	Mouse	Brain	HP_ad_rep7	4.9e-20
Large2	GOBP_Protein_O_Linked_Glycosylation	Mouse	Brain	HP_ad_rep7	5.4e-13
Large2	GOBP_Muscle_Cell_Cellular_Homeostasis	Mouse	Brain	HP_ad_rep8	1.6e-09
Large2	GOBP_Glycoprotein_Metabolic_Process	Mouse	Brain	HP_adpolb_rep1	2.0e-07
Large2	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Large2	GOBP_Cellular_Homeostasis	Mouse	Brain	HP_polb_rep9	1.2e-09
Large2	GOBP_Glycoprotein_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.4e-10
Large2	GOBP_Homeostatic_Process	Mouse	Brain	HP_polb_rep9	6.4e-11

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Large2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Large2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Large2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Large2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Large2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source